Serotype-specific opsonization of Treponema hyodysenteriae.

Abstract:

:Treponema hyodysenteriae was shown to attach to mouse peritoneal cells in the absence of serum opsonins in vitro. If serotype-specific antiserum from pigs was added to the media and treponemes of that corresponding serotype were employed in the assay, the amount of attachment increased an average of 3.7 times that of the control without pig sera. However, the amount of attachment was increased an average of only 1.5 times that of the control if organisms of any noncorresponding serotype of T. hyodysenteriae were used in the assay. Since the lipopolysaccharide (LPS) extracted from T. hyodysenteriae is the basis for serotyping the treponeme, the ability of these distinct LPS types to block attachment by blocking opsonization of the organisms was tested. Attachment, using corresponding antisera and treponemes, was blocked by LPS extracted from treponemes of that serotype, but not by LPS extracted from treponemes of other serotypes. These results indicate that antibody response to T. hyodysenteriae infection in pigs is serotype-specific. Furthermore, since opsonization and subsequent attachment of bacteria to phagocytes is known to be a protective mechanism, we suggest that the LPS may be an important antigen in the stimulation of host defense against the treponeme.

journal_name

Infect Immun

journal_title

Infection and immunity

authors

Nuessen ME,Joens LA

doi

10.1128/IAI.38.3.1029-1032.1982

subject

Has Abstract

pub_date

1982-12-01 00:00:00

pages

1029-32

issue

3

eissn

0019-9567

issn

1098-5522

journal_volume

38

pub_type

杂志文章
  • Ex vivo desequestration of Plasmodium falciparum-infected erythrocytes from human placenta by chondroitin sulfate A.

    abstract::We performed ex vivo experiments with Plasmodium falciparum-infected human placentas from primi- and multigravida women from Cameroon. All women, independent of their gravida status, had anti-chondroitin sulfate A (CSA) adhesion antibodies which cross-reacted with heterologous strains, such as FCR3 and Palo-Alto(FUP)1...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:

    authors: Gysin J,Pouvelle B,Fievet N,Scherf A,Lépolard C

    更新日期:1999-12-01 00:00:00

  • Mechanisms of resistance of Porphyromonas gingivalis to killing by serum complement.

    abstract::The complement system plays an important role in the host defense against infection, and the formation of the terminal complement complex on the bacterial surface has been shown to be particularly important in killing of gram-negative bacteria. The gram-negative periodontal pathogen Porphyromonas gingivalis is resista...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00304-06

    authors: Slaney JM,Gallagher A,Aduse-Opoku J,Pell K,Curtis MA

    更新日期:2006-09-01 00:00:00

  • Isolation of Neisseria gonorrhoeae mutants that show enhanced trafficking across polarized T84 epithelial monolayers.

    abstract::Initiation of a gonococcal infection involves attachment of Neisseria gonorrhoeae to the plasma membrane of an epithelial cell in the mucosal epithelium and its internalization, transepithelial trafficking, and exocytosis from the basal membrane. Piliation and expression of certain Opa proteins and the immunoglobulin ...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/iai.68.2.896-905.2000

    authors: Hopper S,Wilbur JS,Vasquez BL,Larson J,Clary S,Mehr IJ,Seifert HS,So M

    更新日期:2000-02-01 00:00:00

  • Mitogenic stimulation of murine spleen cells: relation to susceptibility to Salmonella infection.

    abstract::The screening of several inbred strains of mice suggested that the capacity of their spleen cells to respond to the mitogenic effect of lipopolysaccharide (LPS) of gram-negative bacteria was correlated with their resistance to intraperitoneal infection with Salmonella typhimurium. An infection of LPS into mice caused ...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.15.1.26-33.1977

    authors: von Jeney N,Günther E,Jann K

    更新日期:1977-01-01 00:00:00

  • Interaction of Bartonella henselae with endothelial cells promotes monocyte/macrophage chemoattractant protein 1 gene expression and protein production and triggers monocyte migration.

    abstract::Bacillary angiomatosis (BA), one of the many clinical manifestations resulting from infection with the facultative intracellular bacterium Bartonella henselae, is characterized by angiogenic lesions. Macrophages have been identified as important effector cells contributing to the angiogenic process during B. henselae ...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.73.9.5735-5742.2005

    authors: McCord AM,Burgess AW,Whaley MJ,Anderson BE

    更新日期:2005-09-01 00:00:00

  • Involvement of fractalkine/CX3CL1 expression by dendritic cells in the enhancement of host immunity against Legionella pneumophila.

    abstract::Legionnaires' disease is clinically manifested as severe pneumonia caused by Legionella pneumophila. However, the dendritic cell (DC)-centered immunological framework of the host defense against L. pneumophila has not been fully delineated. For this study, we focused on a potent chemoattractant for lymphocytes, fracta...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.73.9.5350-5357.2005

    authors: Kikuchi T,Andarini S,Xin H,Gomi K,Tokue Y,Saijo Y,Honjo T,Watanabe A,Nukiwa T

    更新日期:2005-09-01 00:00:00

  • Antrum- and corpus mucosa-infiltrating CD4(+) lymphocytes in Helicobacter pylori gastritis display a Th1 phenotype.

    abstract::In this study, cytokine patterns produced by CD4(+) T cells isolated from antrum or corpus gastral biopsy specimens of 10 patients with Helicobacter pylori-positive gastritis were compared. To this end, expression of intracellular cytokines (interleukin-4 [IL-4] and gamma interferon) and of CD4 was assessed by flow cy...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.66.11.5543-5546.1998

    authors: Sommer F,Faller G,Konturek P,Kirchner T,Hahn EG,Zeus J,Röllinghoff M,Lohoff M

    更新日期:1998-11-01 00:00:00

  • Incremental Contributions of FbaA and Other Impetigo-Associated Surface Proteins to Fitness and Virulence of a Classical Group A Streptococcal Skin Strain.

    abstract::Group A streptococci (GAS) are highly prevalent human pathogens whose primary ecological niche is the superficial epithelial layers of the throat and/or skin. Many GAS strains with a strong tendency to cause pharyngitis are distinct from strains that tend to cause impetigo; thus, genetic differences between them may c...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00374-17

    authors: Rouchon CN,Ly AT,Noto JP,Luo F,Lizano S,Bessen DE

    更新日期:2017-10-18 00:00:00

  • Experimental model for dermal granulomatous hypersensitivity in Q fever.

    abstract::Q fever has been associated with granulomatous changes in clinical biopsy material obtained from liver and bone marrow. Local reactions to skin testing have been described in previously sensitized humans, but histological studies of such reactions have not been reported. We note that delayed hypersensitivity reactions...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.39.1.388-393.1983

    authors: Ascher MS,Berman MA,Parker D,Turk JL

    更新日期:1983-01-01 00:00:00

  • Antigenic specificity of convalescent serum from cattle with haemophilus somnus-induced experimental abortion.

    abstract::The antigens of Haemophilus somnus recognized by convalescent bovine serum were studied by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotting with a protein A-peroxidase conjugate. The same two 76K and 40K antigens were predominant in whole-bacterium preparations and in outer-membrane-enric...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.55.6.1381-1386.1987

    authors: Corbeil LB,Arthur JE,Widders PR,Smith JW,Barbet AF

    更新日期:1987-06-01 00:00:00

  • Ability of oral bacteria to degrade fibronectin.

    abstract::The fibronectin-degrading ability of 116, mainly oral, strains was assayed by using plasma-derived fibronectin adsorbed to a polystyrene surface. Ability to degrade fibronectin was revealed in strains of Bacteroides gingivalis, Bacteroides intermedius, Bacteroides loeschii, Staphylococcus aureus, Staphylococcus epider...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.51.2.707-711.1986

    authors: Wikström M,Linde A

    更新日期:1986-02-01 00:00:00

  • Regulatory T Cells Contribute to Resistance against Lyme Arthritis.

    abstract::The symptoms of Lyme disease are caused by inflammation induced by species of the Borrelia burgdorferisensu lato complex. The various presentations of Lyme disease in the population suggest that differences exist in the intensity and regulation of the host response to the spirochete. Previous work has described correl...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00160-20

    authors: Siebers EM,Liedhegner ES,Lawlor MW,Schell RF,Nardelli DT

    更新日期:2020-10-19 00:00:00

  • The outer membranes of Brucella spp. are resistant to bactericidal cationic peptides.

    abstract::The actions of polymyxin B, rabbit polymorphonuclear lysosome extracts, 14 polycationic peptides (including defensin NP-2, cecropin P1, lactoferricin B, and active peptides from cationic protein 18 and bactenecin), EDTA, and Tris on Brucella spp. were studied, with other gram-negative bacteria as controls. Brucella sp...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.63.8.3054-3061.1995

    authors: Martínez de Tejada G,Pizarro-Cerdá J,Moreno E,Moriyón I

    更新日期:1995-08-01 00:00:00

  • Glucose and glycolysis are required for the successful infection of macrophages and mice by Salmonella enterica serovar typhimurium.

    abstract::Salmonella is a widespread zoonotic enteropathogen that causes gastroenteritis and fatal typhoidal disease in mammals. During systemic infection of mice, Salmonella enterica serovar Typhimurium resides and replicates in macrophages within the "Salmonella-containing vacuole" (SCV). It is surprising that the substrates ...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00093-09

    authors: Bowden SD,Rowley G,Hinton JC,Thompson A

    更新日期:2009-07-01 00:00:00

  • Comparative infectivity of trachoma organisms in HeLa 229 cells and egg cultures.

    abstract::Thirty-two trachoma strains were simultaneously titrated in the yolk sac of embryonated chicken eggs and in HeLa 229 cells pretreated with diethylaminoethyl-dextran to determine the relative sensitivity of the two culture systems for detection of the infection. The strains tested were both yolk sac- and HeLa cell-esta...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.12.5.1078-1082.1975

    authors: Kuo CC,Wang SP,Grayston JT

    更新日期:1975-11-01 00:00:00

  • Cooperation, quorum sensing, and evolution of virulence in Staphylococcus aureus.

    abstract::The virulence and fitness in vivo of the major human pathogen Staphylococcus aureus are associated with a cell-to-cell signaling mechanism known as quorum sensing (QS). QS coordinates the production of virulence factors via the production and sensing of autoinducing peptide (AIP) signal molecules by the agr locus. Her...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.01216-13

    authors: Pollitt EJ,West SA,Crusz SA,Burton-Chellew MN,Diggle SP

    更新日期:2014-03-01 00:00:00

  • Impairment of melibiose utilization in Streptococcus mutans serotype c gtfA mutants.

    abstract::The Streptococcus mutans serotype c gtfA gene encodes a 55-kilodalton sucrose-hydrolyzing enzyme. Analysis of S. mutans gtfA mutants revealed that the mutant strains were specifically impaired in the ability to use melibiose as a sole carbon source. S. mutans gtfA mutant strains synthesized less alpha-galactosidase ac...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.57.3.992-995.1989

    authors: Barletta RG,Curtiss R 3rd

    更新日期:1989-03-01 00:00:00

  • Macrophage Migration Inhibition Studies with Cells from Mice Vaccinated with Cell Walls of Mycobacterium bovis BCG: Characterization of the Experimental System.

    abstract::The macrophage migration inhibition test was applied to the study of delayed hypersensitivity in mice vaccinated intravenously with oil-treated cell walls of Mycobacterium bovis BCG. Migration inhibition of peritoneal exudate cells from sensitized mice was demonstrated directly upon incubation of the cells with purifi...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.1.6.587-594.1970

    authors: Yamamoto K,Anacker RL

    更新日期:1970-06-01 00:00:00

  • Neutrophils are essential for rapid clearance of Enterococcus faecium in mice.

    abstract::A progressive increase in infections with multiresistant Enterococcus faecium has been reported, especially in cancer patients and neutropenic patients. Despite its increasing importance as a nosocomial pathogen, knowledge of the pathogenesis of E. faecium infections is highly limited. In this study, we investigated t...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00863-08

    authors: Leendertse M,Willems RJ,Giebelen IA,Roelofs JJ,Bonten MJ,van der Poll T

    更新日期:2009-01-01 00:00:00

  • Role of antiviral antibodies in resistance against coxsackievirus B3 infection: interaction between preexisting antibodies and an interferon inducer.

    abstract::An experimental model of coxsackievirus B3 infection in newborn mice was utilized to examine the protective role of antiviral antibodies and an interferon inducer, polyinosinic acid-polycytidylic acid [poly(I:C)]. Subcutaneous administration to the infected mice of specific antiviral antibodies resulted in significant...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.37.2.720-727.1982

    authors: Cho CT,Feng KK,McCarthy VP,Lenahan MF

    更新日期:1982-08-01 00:00:00

  • Surface hydrophobicity, adherence, and aggregation of cell surface protein antigen mutants of Streptococcus mutans serotype c.

    abstract::The pac gene of the serotype c strain Streptococcus mutans MT8148 encodes a cell surface protein antigen (PAc) of approximate 190 kilodaltons. The serotype c strain S. mutans GS-5 does not produce the 190-kilodalton PAc but produces a lower-molecular-weight protein that reacts with anti-PAc serum. The SphI-BamHI fragm...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.58.2.289-296.1990

    authors: Koga T,Okahashi N,Takahashi I,Kanamoto T,Asakawa H,Iwaki M

    更新日期:1990-02-01 00:00:00

  • Immunity to influenza in ferrets. X. Intranasal immunization of ferrets with inactivated influenza A virus vaccines.

    abstract::The response of ferrets after intranasal inoculation of inactivated A/Hong Kong/68 (H3N2) influenza virus vaccines is reported. Normal ferrets given either saline vaccine in drops or freeze-dried vaccine in an aerosol intranasally did not produce detectable serum or nasal hemagglutination inhibiting antibody and were ...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.9.6.985-990.1974

    authors: McLaren C,Potter CW,Jennings R

    更新日期:1974-06-01 00:00:00

  • Cloning and expression in Escherichia coli of the gene encoding the heat-modifiable major outer membrane protein of Haemophilus influenzae type b.

    abstract::One major outer membrane protein (P1) of Haemophilus influenzae type b (Hib), with an apparent molecular weight of 34,000 (34K) as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), has been shown to be heat modifiable. After heating at 100 degrees C for 5 min in 2% SDS, the P1 protein...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.55.12.2993-3000.1987

    authors: Gonzales FR,Leachman S,Norgard MV,Radolf JD,McCracken GH Jr,Evans C,Hansen EJ

    更新日期:1987-12-01 00:00:00

  • The down-regulation of cathepsin G in THP-1 monocytes after infection with Mycobacterium tuberculosis is associated with increased intracellular survival of bacilli.

    abstract::Cathepsin G (CatG) is a serine protease found in the azurophilic granules of monocytes that is known to have antimicrobial properties, but its role in Mycobacterium tuberculosis infection is unknown. We found that M. tuberculosis infection of human THP-1 monocytic cells induced the down-regulation of CatG mRNA express...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.72.10.5712-5721.2004

    authors: Rivera-Marrero CA,Stewart J,Shafer WM,Roman J

    更新日期:2004-10-01 00:00:00

  • Capsule reduces adherence of enterotoxigenic Escherichia coli to isolated intestinal epithelial cells of pigs.

    abstract::Previous reports have demonstrated that heat-stable (A-type) capsule on piliated enterotoxigenic Escherichia coli enhances colonization of enterotoxigenic E. coli in the small intestine and enhances virulence of enterotoxigenic E. coli. In this report, four encapsulated enterotoxigenic E. coli strains and one encapsul...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.45.3.737-740.1984

    authors: Runnels PL,Moon HW

    更新日期:1984-09-01 00:00:00

  • Etiology of chronic pneumonia in rats and a study of the experimental disease in mice.

    abstract::The lungs of conventional rats with chronic pneumonia contained Streptobacillus moniliformis and Mycoplasma pulmonis. These organisms singly and in combination failed to produce lung disease when inoculated into specific pathogen-free rats. On the other hand, diseased lung homogenate not containing cultivable organism...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.6.1.83-91.1972

    authors: Gay FW,Maguire ME,Baskerville A

    更新日期:1972-07-01 00:00:00

  • Molecular cloning and characterization of a 35.5-kilodalton lipoprotein of Treponema pallidum.

    abstract::A clone expressing a 35.5-kDa recombinant treponemal protein was isolated from a genomic DNA library constructed from Treponema pallidum street strain 14. Polyclonal antiserum raised against the recombinant protein reacted with a corresponding native protein of comparable size in T. pallidum that is specific to the pa...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.59.4.1521-1528.1991

    authors: Hubbard CL,Gherardini FC,Bassford PJ Jr,Stamm LV

    更新日期:1991-04-01 00:00:00

  • Host defenses in murine malaria: analysis of plasmodial infection-caused defects in macrophage microbicidal capacities.

    abstract::Macrophage-dependent killing of facultative intracellular bacteria was markedly impaired by overt erythrocytic Plasmodium yoelii or Plasmodium berghei infection of mice. P. yoelii infection was capable of ablating not only the macrophage microbicidal capacity of "normal" animals but also the bactericidal capacities of...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.31.1.396-407.1981

    authors: Murphy JR

    更新日期:1981-01-01 00:00:00

  • Scavenger receptor A dampens induction of inflammation in response to the fungal pathogen Pneumocystis carinii.

    abstract::Alveolar macrophages are the effector cells largely responsible for clearance of Pneumocystis carinii from the lungs. Binding of organisms to beta-glucan and mannose receptors has been shown to stimulate phagocytosis of the organisms. To further define the mechanisms used by alveolar macrophages for clearance of P. ca...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00393-07

    authors: Hollifield M,Bou Ghanem E,de Villiers WJ,Garvy BA

    更新日期:2007-08-01 00:00:00

  • Failure of CD4 T Cell-Deficient Hosts To Control Chronic Nontyphoidal Salmonella Infection Leads to Exacerbated Inflammation, Chronic Anemia, and Altered Myelopoiesis.

    abstract::Immunocompromised patients are more susceptible to recurrent nontyphoidal Salmonella (NTS) bacteremia. A key manifestation of HIV infection is the loss of CD4 T cells, which are crucial for immunity to Salmonella infection. We characterized the consequences of CD4 T cell depletion in mice where virulent Salmonella est...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00417-20

    authors: Loomis WP,Delaney MA,Johnson ML,Cookson BT

    更新日期:2020-12-15 00:00:00