Macrophage Migration Inhibition Studies with Cells from Mice Vaccinated with Cell Walls of Mycobacterium bovis BCG: Characterization of the Experimental System.

abstract：:In mammals, the natural resistance-associated macrophage protein 1 gene, Nramp1, plays a major role in resistance to mycobacterial infections. Chesapeake Bay striped bass (Morone saxatilis) is currently experiencing an epizootic of mycobacteriosis that threatens the health of this ecologically and economically importa...

journal_title：Infection and immunity

authors： Burge EJ,Gauthier DT,Ottinger CA,Van Veld PA

更新日期：2004-03-01 00:00:00

abstract：:Candida albicans is a commensal organism that under certain circumstances can become pathogenic. During systemic infection C. albicans is disseminated via the circulation to distant organs, where it causes multiple organ failure. Despite the severity of systemic C. albicans infection, little is known about the mechani...

journal_title：Infection and immunity

authors： Grubb SE,Murdoch C,Sudbery PE,Saville SP,Lopez-Ribot JL,Thornhill MH

更新日期：2009-09-01 00:00:00

abstract：:Each of the serotypes of Haemophilus influenzae (types a to f) may colonize the respiratory tract of humans, but only type b strains commonly cause invasive systemic infections. To investigate the role of complement in immunity to encapsulated non-type b strains, rats were depleted of C3 with cobra venom factor and ch...

journal_title：Infection and immunity

authors： Corrall CJ,Winkelstein JA,Moxon ER

更新日期：1982-03-01 00:00:00

abstract：:Anti-rabbit alveolar macrophage goat serum (AMS), adsorbed of hemolysins and hemagglutinins, exhibited complement-dependent cytotoxicity for the following rabbit target cells: alveolar macrophages, thymocytes, and kidney (RK-13) cells. The intravenous injection of AMS, sufficient to reduce markedly the dermal tubercul...

journal_title：Infection and immunity

authors： Moore VL,Myrvik QN

更新日期：1970-12-01 00:00:00

abstract：:Toxoplasma gondii is a ubiquitous parasite that persists for the life of a healthy mammalian host. A latent, chronic infection can reactivate upon immunosuppression and cause life-threatening diseases, such as encephalitis. A key to the pathogenesis is the parasite's interconversion between the tachyzoite (in acute in...

journal_title：Infection and immunity

authors： Kim SK,Karasov A,Boothroyd JC

更新日期：2007-04-01 00:00:00

abstract：:Reinfection of immune mice with Leishmania major elicits a secondary gamma interferon (IFN-gamma) response to which specific CD8+ T cells are essential. We have shown previously that specific CD8+ T cells from reinfected immune mice release substantially higher levels of IFN-gamma, a cytokine essential for the efficie...

journal_title：Infection and immunity

authors： Müller I,Kropf P,Louis JA,Milon G

更新日期：1994-06-01 00:00:00

abstract：:Although the periodontal pathogen Porphyromonas gingivalis must withstand high levels of nitrosative stress while in the oral cavity, the mechanisms of nitrosative stress defense are not well understood in this organism. Previously we showed that the transcriptional regulator HcpR plays a significant role in defense, ...

journal_title：Infection and immunity

authors： Belvin BR,Gui Q,Hutcherson JA,Lewis JP

更新日期：2019-03-25 00:00:00

abstract：:The outer membrane proteins of Bordetella avium were examined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Sarkosyl-insoluble outer membrane protein-enriched profiles from 50 virulent B. avium isolates, containing major 21,000- and 37,000-molecular-weight proteins (21K and 37K proteins, respectively) ...

journal_title：Infection and immunity

authors： Leyh R,Griffith RW

更新日期：1992-03-01 00:00:00

abstract：:Cholera toxin (CT) and related Escherichia coli enterotoxins LTI and LTIIb have a conserved hydrophobic region at the AB(5) interface postulated to be important for toxin assembly. Hydrophobic residue F223 in the A subunit of CT (CTA) as well as residues 174, L77, and T78 in the B subunit of CT (CTB) were replaced ind...

journal_title：Infection and immunity

authors： Tinker JK,Erbe JL,Hol WG,Holmes RK

更新日期：2003-07-01 00:00:00

abstract：:Chlamydia trachomatis L2 is an obligate intracellular microorganism with a unique biphasic life cycle. The extracellular form, the elementary body (EB), is infectious but metabolically inactive. Attachment of EBs to host cells is medicated by a heparan sulfate-like glycosaminoglycan. Following attachment, the EB is in...

journal_title：Infection and immunity

authors： Birkelund S,Johnsen H,Christiansen G

更新日期：1994-11-01 00:00:00

abstract：:Using a PCR-based strategy and degenerate oligonucleotides, we isolated a Legionella pneumophila gene that showed high sequence similarity to members of the fliI gene family. An insertion mutation that disrupted the fliI open reading frame was recombined onto the L. pneumophila chromosome and analyzed for its effects ...

journal_title：Infection and immunity

authors： Merriam JJ,Mathur R,Maxfield-Boumil R,Isberg RR

更新日期：1997-06-01 00:00:00

abstract：:T lymphocyte subpopulations in the peripheral blood of children with congenital cytomegalovirus infections and in controls were enumerated with monoclonal antibodies. Infants of less than 1 year of age with symptomatic infections showed significant increases in the proportion of suppressor cells and decreases in the r...

journal_title：Infection and immunity

authors： Pass RF,Roper MA,August AM

更新日期：1983-09-01 00:00:00

abstract：:Vitamin E protects nonimmunized and immunized mice against fatal Diplococcus pneumoniae type I (DpI) infection. A dietary supplementation of 180 mg of dl-alpha-tocopheryl acetate per kg of diet increased survival of nonimmunized mice from 20 to 80% when challenged with 20 organisms, and of mice immunized with 0.5 ng o...

journal_title：Infection and immunity

authors： Heinzerling RH,Tengerdy RP,Wick LL,Lueker DC

更新日期：1974-12-01 00:00:00

abstract：:A 46-kDa hemolytic protein, referred to as cystalysin, from Treponema denticola ATCC 35404 was overexpressed in Escherichia coli LC-67. Both the native and recombinant 46-kDa proteins were purified to homogeneity. Both proteins expressed identical biological and functional characteristics. In addition to its biologica...

journal_title：Infection and immunity

authors： Chu L,Ebersole JL,Kurzban GP,Holt SC

更新日期：1997-08-01 00:00:00

abstract：:Secretion of immunoglobulin A1 (IgA1) proteases is a characteristic of Haemophilus influenzae and several other bacterial pathogens causing infectious diseases, including meningitis. Indirect evidence suggests that the proteases are important virulence factors. In this study, we cloned the iga gene encoding immunoglob...

journal_title：Infection and immunity

authors： Poulsen K,Brandt J,Hjorth JP,Thøgersen HC,Kilian M

更新日期：1989-10-01 00:00:00

abstract：:Curli are thin, coiled fibers expressed on the surface of Escherichia coli that bind several matrix and plasma proteins such as fibronectin, laminin, plasminogen, tissue plasminogen activator, and H-kininogen. In this work, we examined the interactions between curli-expressing E. coli and human major histocompatibilit...

journal_title：Infection and immunity

authors： Olsén A,Wick MJ,Mörgelin M,Björck L

更新日期：1998-03-01 00:00:00

abstract：:Vibrio cholerae is a monoflagellated gram-negative bacterium that causes the severe diarrheal disease cholera. In contrast to Salmonella enterica serovar Typhimurium infection, which is accompanied by both acute diarrhea and high-level inflammation, V. cholerae infection is largely noninflammatory in human hosts. Bact...

journal_title：Infection and immunity

authors： Yoon SS,Mekalanos JJ

更新日期：2008-03-01 00:00:00

abstract：:The distribution of dengue-2 antigens was studied in infected monkey kidney cells (LLC MK2) using an indirect, horseradish peroxidase-conjugated immunoglobulin technique. This procedure allowed both light and electron microscopic examination of serial-step sections of individual cells cut in a plane perpendicular to t...

journal_title：Infection and immunity

authors： Cardiff RD,Lund JK

更新日期：1976-06-01 00:00:00

abstract：:Amebic erythrophagocytosis is characteristic of invasive amebiasis, and mutants deficient in erythrocyte ingestion are avirulent. We sought to understand the molecular mechanisms underlying erythrocyte phagocytosis by Entamoeba histolytica. Following adherence to amebae, erythrocytes became round and crenulated, and p...

journal_title：Infection and immunity

authors： Boettner DR,Huston CD,Sullivan JA,Petri WA Jr

更新日期：2005-06-01 00:00:00

abstract：:Leishmaniae are protozoans which, depending upon both the host and parasite species, can cause either a healing or nonhealing infection. While C57BL/10 mice are able to heal following infection with Leishmania major, they fail to heal following infection with Leishmania amazonensis. In order to address the role of Th1...

journal_title：Infection and immunity

authors： Afonso LC,Scott P

更新日期：1993-07-01 00:00:00

abstract：:Eperythrozoon coccoides is a common blood parasite of rodents and the etiological agent of a chronic infection present in many mouse colonies. After primary infection, mice develop a parasitemia and anemia followed by a chronic, latent infection. During the acute phase of infection, mice manifest a striking suppressio...

journal_title：Infection and immunity

authors： Glasgow LA,Odugbemi T,Dwyer P,Ritterson AL

更新日期：1971-10-01 00:00:00

abstract：:The eib genes of Escherichia coli encode surface-exposed proteins which bind immunoglobulins (Ig) such as the Fc fragment of human IgG (IgG Fc) in a nonimmune manner. The Eib proteins belong to a family which includes YadA of Yersinia, UspA2 of Moraxella, and DsrA of Haemophilus ducreyi. This family of surface-exposed...

journal_title：Infection and immunity

authors： Sandt CH,Hill CW

更新日期：2001-12-01 00:00:00

abstract：:Pyolysin (PLO), the hemolytic exotoxin expressed by Arcanobacterium (Actinomyces) pyogenes, is a member of the thiol-activated cytolysin family of bacterial toxins. Insertional inactivation of the plo gene results in loss of expression of PLO with a concomitant loss in hemolytic activity. The plo mutant, PLO-1, has an...

journal_title：Infection and immunity

authors： Jost BH,Songer JG,Billington SJ

更新日期：1999-04-01 00:00:00

abstract：:Bordetella pertussis is the causative agent of whooping cough, a potentially lethal respiratory disease in children. In immunocompetent individuals, B. pertussis infection elicits an effective adaptive immune response driven by activated CD4(+) T cells. However, live B. pertussis persists in the host for 3 to 4 weeks ...

journal_title：Infection and immunity

authors： Shumilla JA,Lacaille V,Hornell TM,Huang J,Narasimhan S,Relman DA,Mellins ED

更新日期：2004-03-01 00:00:00

abstract：:Escherichia coli and other members of the family Enterobacteriaceae express surface fibrillar structures, fimbriae, that promote bacterial adhesion to host receptors. Type 1 fimbriae possess a lectinlike component, FimH, that is commonly thought to cause binding to mannose-containing oligosaccharides of host receptors...

journal_title：Infection and immunity

authors： Sokurenko EV,Courtney HS,Abraham SN,Klemm P,Hasty DL

更新日期：1992-11-01 00:00:00

abstract：:Colonization of the mucosa of the stomach and the duodenum by Helicobacter pylori is the major cause of acute and chronic gastroduodenal pathologies in humans. Duodenal ulcer formation strongly correlates with the expression of an antigen (CagA) that is usually coeexpressed with the vacuolating cytotoxin (VacA), a pro...

journal_title：Infection and immunity

authors： Xiang Z,Censini S,Bayeli PF,Telford JL,Figura N,Rappuoli R,Covacci A

更新日期：1995-01-01 00:00:00

abstract：:Tuberculosis (TB) remains an enormous global health problem, and a new vaccine against TB more potent than the current inadequate vaccine, Mycobacterium bovis BCG, is urgently needed. We describe a recombinant BCG vaccine (rBCG30) expressing and secreting the 30-kDa major secretory protein of Mycobacterium tuberculosi...

journal_title：Infection and immunity

authors： Horwitz MA,Harth G

更新日期：2003-04-01 00:00:00

abstract：:Inoculation of herpes simplex virus on the forehead and/or snout of hairless mice resulted in a significantly lower mortality rate than inoculation of the skin in the lumbosacral area. Latent herpes simplex virus infections were detected in all forehead-inoculated and in 90% of snout-inoculated mice. Phosphonoacetic a...

journal_title：Infection and immunity

authors： Klein RJ,Friedman-Kien AE,Yellin PB

更新日期：1978-04-01 00:00:00

abstract：:Peptide 9 (TDAYNQKLSERRAN) and peptide 10 (NATAEGRAINRRVE) represent surface-exposed epitopes of outer membrane protein F of Pseudomonas aeruginosa. Rats immunized with four intramuscular inoculations on days 0, 14, 28, and 42 with either peptide 9 or peptide 10 conjugated to keyhole limpet hemocyanin were afforded pr...

journal_title：Infection and immunity

authors： Gilleland LB,Gilleland HE Jr

更新日期：1995-06-01 00:00:00

abstract：:Infection with Histoplasma capsulatum results in a subclinical infection in immunocompetent hosts due to an effective cellular immune response. By contrast, immunodeficient individuals can have a severe disseminated and potentially fatal disease. In a previous study, it was demonstrated that normal mice infected intra...

journal_title：Infection and immunity

authors： Zhou P,Sieve MC,Tewari RP,Seder RA

更新日期：1997-03-01 00:00:00