Distribution of dengue-2 antigens by electron immunocytochemistry.

abstract：:Bordetella pertussis, a causative agent of whooping cough, expresses BrkA, which confers serum resistance, but the closely related human pathogen that also causes whooping cough, Bordetella parapertussis, does not. Interestingly, B. parapertussis, but not B. pertussis, produces an O antigen, a factor shown in other mo...

journal_title：Infection and immunity

authors： Goebel EM,Wolfe DN,Elder K,Stibitz S,Harvill ET

更新日期：2008-04-01 00:00:00

abstract：:Tissue macrophages are the obligatory host cells for Leishmania donovani, the causative agent of visceral leishmaniasis. In this study we sought to determine whether activated macrophages, as defined by the functional criterion of tumor cell cytotoxicity, were also able to exert a microbicidal effect on ingested L. do...

journal_title：Infection and immunity

authors： Haidaris CG,Bonventre PF

更新日期：1981-09-01 00:00:00

abstract：:The dermotropism of Cryptococcus neoformans SLHA in congenitally athymic (nu/nu) and doubly immunodeficient beige-athymic (bg/bg-nu/nu) mice is described. Both bg/bg-nu/nu and nu/nu mice developed cutaneous cryptococcosis within 7 to 12 days following intravenous challenge with 10(4) encapsulated yeast cells. Macrosco...

journal_title：Infection and immunity

authors： Salkowski CA,Balish E

更新日期：1991-05-01 00:00:00

abstract：:Colonization of the mucosa of the stomach and the duodenum by Helicobacter pylori is the major cause of acute and chronic gastroduodenal pathologies in humans. Duodenal ulcer formation strongly correlates with the expression of an antigen (CagA) that is usually coeexpressed with the vacuolating cytotoxin (VacA), a pro...

journal_title：Infection and immunity

authors： Xiang Z,Censini S,Bayeli PF,Telford JL,Figura N,Rappuoli R,Covacci A

更新日期：1995-01-01 00:00:00

abstract：:Toxoplasma gondii is an obligate intracellular parasite that resides in the cytoplasm of its host in a unique membrane-bound vacuole known as the parasitophorous vacuole (PV). The membrane surrounding the parasite is remodeled by the dense granules, secretory organelles that release an array of proteins into the vacuo...

journal_title：Infection and immunity

authors： Rome ME,Beck JR,Turetzky JM,Webster P,Bradley PJ

更新日期：2008-11-01 00:00:00

abstract：:Salmonella enterica subspecies I serovars are common bacterial pathogens causing diseases ranging from enterocolitis to systemic infections. Some serovars are adapted to specific hosts, whereas others have a broad host range. The molecular mechanisms defining the virulence characteristics and the host range of a given...

journal_title：Infection and immunity

authors： Suar M,Jantsch J,Hapfelmeier S,Kremer M,Stallmach T,Barrow PA,Hardt WD

更新日期：2006-01-01 00:00:00

abstract：:Genetic resistance to lethal infection with Rickettsia tsutsugamushi was studied in over 30 inbred strains, inbred hybrids, and outbred stocks of mice. Inbred mice infected intraperitoneally with the Gilliam strain of R. tsutsugamushi showed three patterns of response: susceptible (A/HeJ, C3H/HeDub, C3H/HeJ, C3H/HeN, ...

journal_title：Infection and immunity

authors： Groves MG,Osterman JV

更新日期：1978-02-01 00:00:00

abstract：:Protective immunity to Plasmodium falciparum malaria acquired after natural exposure is largely antibody mediated. IgG-specific P. falciparum EMP1 (PfEMP1) proteins on the infected erythrocyte surface are particularly important. The transient antibody responses and the slowly acquired protective immunity probably refl...

journal_title：Infection and immunity

authors： Ampomah P,Stevenson L,Ofori MF,Barfod L,Hviid L

更新日期：2014-05-01 00:00:00

abstract：:Antisera against isolated cell surface preparations (PCSP-As) of Leishmania donovani promastigotes were used to detect extracellular antigens produced during the growth of these organisms in four different growth media. The PCSP-As precipitated two major antigenically identical but electrophoretically distinct compone...

journal_title：Infection and immunity

authors： Kaneshiro ES,Gottlieb M,Dwyer DM

更新日期：1982-08-01 00:00:00

abstract：:The influence of D-alanine and carbohydrate substitution of lipoteichoic acids (LTAs) on the binding of antibody directed to the polyglycerol phosphate (PGP) portion was found to be at least partially dependent upon the mode of presentation of the antigen. There were greater differences in binding of anti-PGP immunogl...

journal_title：Infection and immunity

authors： Kessler RE,Thivierge BH

更新日期：1983-08-01 00:00:00

abstract：:To assess the relationship between the within-host diversity of malaria infections and the susceptibility of the host to subsequent infection, we genotyped 60 children's successive infections from birth through 3 years of life. MSP-1 Block2 genotypes were used to estimate the complexity of infection (COI). Malaria tra...

journal_title：Infection and immunity

authors： Branch OH,Takala S,Kariuki S,Nahlen BL,Kolczak M,Hawley W,Lal AA

更新日期：2001-12-01 00:00:00

abstract：:We purified three proline-rich antimicrobial peptides from elastase-treated extracts of sheep and goat leukocytes and subjected two of them, OaBac5alpha and ChBac5, to detailed analysis. OaBac5alpha and ChBac5 were homologous to each other and to bovine Bac5. Both exhibited potent, broad-spectrum antimicrobial activit...

journal_title：Infection and immunity

authors： Shamova O,Brogden KA,Zhao C,Nguyen T,Kokryakov VN,Lehrer RI

更新日期：1999-08-01 00:00:00

abstract：:The role of glycosylinositol phospholipid 1 (GIPL-1) of Leishmania (Leishmania) major in the interaction of promastigotes and amastigotes with macrophages was analyzed. Monoclonal antibody MEST-1, which recognizes glycolipids containing terminal galactofuranose (Galf) residues (E. Suzuki, M. S. Toledo, H. K. Takahashi...

journal_title：Infection and immunity

authors： Suzuki E,Tanaka AK,Toledo MS,Takahashi HK,Straus AH

更新日期：2002-12-01 00:00:00

abstract：:Lipopolysaccharides (LPS), either in the free form or complexed to CD14, a LPS receptor, are elicitors of the immune system. Lactoferrin (Lf), a LPS-chelating glycoprotein, protects animals against septic shock. Since optimal protection requires administration of Lf prior to lethal doses of LPS, we hypothesized that i...

journal_title：Infection and immunity

authors： Baveye S,Elass E,Fernig DG,Blanquart C,Mazurier J,Legrand D

更新日期：2000-12-01 00:00:00

abstract：:To assess the humoral immunological responses at the subclass level in shigellosis, specific antibody responses against Shigella dysenteriae 1 lipopolysaccharide (LPS), S. flexneri Y LPS, invasion plasmid-coded protein antigens (Ipa), and Shiga toxin were analyzed. Antibody responses of 41 patients with S. dysenteriae...

journal_title：Infection and immunity

authors： Islam D,Wretlind B,Ryd M,Lindberg AA,Christensson B

更新日期：1995-05-01 00:00:00

abstract：:The cellular source of interleukin-6 (IL-6) during infection of mice with Listeria monocytogenes was investigated both in vitro and in vivo. Peritoneal cells taken at intervals from infected mice and cultured in vitro without added stimulus produced high titers of IL-6 peaking 2 days postinfection in a time course sim...

journal_title：Infection and immunity

authors： Liu Z,Cheers C

更新日期：1993-06-01 00:00:00

abstract：:We have demonstrated that possession of the gene for thermostable direct hemolysin-related hemolysin (trh) coincides with the presence of the urease gene among clinical Vibrio parahaemolyticus strains and that the location of the two genes are in close proximity on the chromosome. Here, we cloned and sequenced the 15,...

journal_title：Infection and immunity

authors： Park KS,Iida T,Yamaichi Y,Oyagi T,Yamamoto K,Honda T

更新日期：2000-10-01 00:00:00

abstract：:While investigating the requirement for phagosomal alkalinization in the host defense against pulmonary aspergillosis, we observed high morbidity of p47(phox)(-/-) mice infected with pH-insensitive Aspergillus nidulans mutants despite a paucity of fungal growth. Fatal infection also resulted from a normally avirulent ...

journal_title：Infection and immunity

authors： Bignell E,Negrete-Urtasun S,Calcagno AM,Arst HN Jr,Rogers T,Haynes K

更新日期：2005-08-01 00:00:00

abstract：:Streptococcus iniae causes meningoencephalitis and death in commercial fish species and has recently been identified as an emerging human pathogen producing fulminant soft tissue infection. As identified by pulsed-field gel electrophoresis (PFGE), strains causing disease in either fish or humans belong to a single clo...

journal_title：Infection and immunity

authors： Fuller JD,Bast DJ,Nizet V,Low DE,de Azavedo JC

更新日期：2001-04-01 00:00:00

abstract：:In the mouse model of Lyme borreliosis, the host immune response during infection with Borrelia burgdorferi results in the remission of carditis and arthritis, as well as global reduction of spirochete numbers in tissues, without elimination of infection. These events were recapitulated by passive transfer of immune s...

journal_title：Infection and immunity

authors： Barthold SW,Hodzic E,Tunev S,Feng S

更新日期：2006-08-01 00:00:00

abstract：:In this study, the role of the hepatobiliary system in the early pathogenesis of Salmonella enteritidis infection was investigated in a rat model. Intravenous (i.v.) challenge with lipopolysaccharide (LPS) has previously been shown to enhance the translocation of normal gut flora. We first confirmed that LPS can simil...

journal_title：Infection and immunity

authors： Islam AF,Moss ND,Dai Y,Smith MS,Collins AM,Jackson GD

更新日期：2000-01-01 00:00:00

abstract：:Cattle are an important reservoir of Shiga toxin-producing enterohemorrhagic Escherichia coli (EHEC) O157:H7 strains, foodborne pathogens that cause hemorrhagic colitis and hemolytic uremic syndrome in humans. EHEC O157:H7 strains are not pathogenic in calves >3 weeks old. Our objective was to determine if EHEC O157:H...

journal_title：Infection and immunity

authors： Dean-Nystrom EA,Bosworth BT,Cray WC Jr,Moon HW

更新日期：1997-05-01 00:00:00

abstract：:A dextranase preparation (AD17) partially purified from a culture liquor of Spicaria violacea strain IFO 6120 significantly inhibited the formation of artifcial dental plaque on a steel wire or on an extracted tooth surface. Changes in the surface morphology of Streptococcus mutans cells due to AD17 action were studie...

journal_title：Infection and immunity

authors： Hamada S,Mizuno J,Murayama Y,Ooshima Y,Masuda N

更新日期：1975-12-01 00:00:00

abstract：:The enteric pathogen Shigella is one of the leading causes of moderate-to-severe diarrhea and death in young children in developing countries. Transformed cell lines and animal models have been widely used to study Shigella pathogenesis. In addition to altered physiology, transformed cell lines are composed of a singl...

journal_title：Infection and immunity

authors： Ranganathan S,Doucet M,Grassel CL,Delaine-Elias B,Zachos NC,Barry EM

更新日期：2019-03-25 00:00:00

abstract：:Athymic BALB/c nude mice and euthymic BALB/c mice were infected with Rickettsia akari by the intraperitoneal route. The rickettsialpox infection was terminated in euthymic mice with only two intraperitoneal injections of the antibiotic oxytetracycline, whereas prolonged treatment was necessary to terminate the infecti...

journal_title：Infection and immunity

authors： Kenyon RH,Pedersen CE Jr

更新日期：1980-05-01 00:00:00

abstract：:A plaque assay system for pathogenic rickettsiae, which utilizes primary chick embryo tissue cultures, is described. It proved to be a highly reproducible measure of infectiousness for Rickettsia rickettsi and R. typhi, which were employed in most studies; as well as for R. canada, R. prowazeki, R. sibirica, R. akari,...

journal_title：Infection and immunity

authors： Wike DA,Tallent G,Peacock MG,Ormsbee RA

更新日期：1972-05-01 00:00:00

abstract：:Monoclonal antibodies secreted by six hybridomas and recognizing antigenic sites on glycoproteins gC, gAB, gD, gE, and gF of herpes simplex virus type 2 were examined for their ability to protect BALB/c mice from lethal infection by the virus. Administration of monoclonal antibodies to individual glycoproteins intrape...

journal_title：Infection and immunity

authors： Balachandran N,Bacchetti S,Rawls WE

更新日期：1982-09-01 00:00:00

abstract：:This study determined the role of crl in the production of curli by, the hemagglutination activity of, and fibronectin binding by avian pathogenic Escherichia coli chi 7122. Curli, an extracellular structure that binds fibronectin, was recently described (A. Olsén, A. Jonsson, and S. Normark, Nature [London] 338:652-6...

journal_title：Infection and immunity

authors： Provence DL,Curtiss R 3rd

更新日期：1992-11-01 00:00:00

abstract：:Rhodococcus equi is a facultative intracellular pathogen of macrophages, relying on the presence of a conjugative virulence plasmid harboring a 21-kb pathogenicity island (PAI) for growth in host macrophages. The PAI encodes a family of 6 virulence-associated proteins (Vaps) in addition to 20 other proteins. The contr...

journal_title：Infection and immunity

authors： Coulson GB,Miranda-CasoLuengo AA,Miranda-CasoLuengo R,Wang X,Oliver J,Willingham-Lane JM,Meijer WG,Hondalus MK

更新日期：2015-08-01 00:00:00

abstract：:Fourteen freshly isolated strains of Streptococcus sanguis were obtained from the dental plaque of five healthy adults. Whole saliva was collected concomitant with the plaque isolates from the five subjects, and a second whole saliva sample was collected 10 weeks later. All possible combinations of the first five sali...

journal_title：Infection and immunity

authors： Liljemark WF,Bloomquist CG,Ofstehage JC

更新日期：1979-12-01 00:00:00