Effects of substitution on polyglycerol phosphate-specific antibody binding to lipoteichoic acids.

abstract：:Interstitial lung macrophages from tuberculosis-susceptible I/St and tuberculosis-resistant A/Sn mice demonstrated significant constitutive differences in gene expression levels, whereas in vitro infection of these cells with Mycobacterium tuberculosis had only a modulatory impact on gene expression. We conclude that ...

journal_title：Infection and immunity

authors： Orlova MO,Majorov KB,Lyadova IV,Eruslanov EB,M'lan CE,Greenwood CM,Schurr E,Apt AS

更新日期：2006-06-01 00:00:00

abstract：:Studies were carried out to determine whether treatment of mice with the synthetic adjuvant muramyl dipeptide afforded any resistance to infection with the obligate intracellular protozoan Toxoplasma gondii. Marked resistance to lethal challenge infection was observed in CBA but not C57BL/6 mice pretreated with muramy...

journal_title：Infection and immunity

authors： Krahenbuhl JL,Sharma SD,Ferraresi RW,Remington JS

更新日期：1981-02-01 00:00:00

abstract：:The antigenically conserved proteins of Treponema pallidum subsp. pallidum and four nonpathogenic cultivatable treponemes were investigated by phase partitioning with the nonionic detergent Triton X-114 and immunoblot analysis. None of the T. pallidum integral membrane proteins identified by phase partitioning (deterg...

journal_title：Infection and immunity

authors： Radolf JD,Norgard MV

更新日期：1988-07-01 00:00:00

abstract：:The interaction of Borrelia burgdorferi, the causative agent of Lyme borreliosis, with phagocytic cells induces the activation of NF-kappaB and the expression of proinflammatory cytokines including tumor necrosis factor alpha (TNF-alpha). B. burgdorferi-induced TNF-alpha production is also dependent on the activation ...

journal_title：Infection and immunity

authors： Olson CM,Hedrick MN,Izadi H,Bates TC,Olivera ER,Anguita J

更新日期：2007-01-01 00:00:00

abstract：:We investigated the effect of a pH 4-treated human immunoglobulin preparation for intravenous use (pH4-G) on the production of tumor necrosis factor alpha (TNF-alpha) in vivo. The level of TNF-alpha in the sera of rabbits receiving pH4-G before lipopolysaccharide (LPS) injection was lower than that in rabbits receivin...

journal_title：Infection and immunity

authors： Shimozato T,Iwata M,Tamura N

更新日期：1990-05-01 00:00:00

abstract：:Trypanosoma cruzi species is categorized into six discrete typing units (TcI to TcVI) of which TcI is most abundantly noted in the sylvatic transmission cycle and considered the major cause of human disease. In our study, the TcI strains Colombiana (COL), SylvioX10/4 (SYL), and a cultured clone (TCC) exhibited differe...

journal_title：Infection and immunity

authors： Zago MP,Hosakote YM,Koo SJ,Dhiman M,Piñeyro MD,Parodi-Talice A,Basombrio MA,Robello C,Garg NJ

更新日期：2016-05-24 00:00:00

abstract：:In this study we used Escherichia coli strain F11(P155) of porcine origin. The heat-stable enterotoxin (ST) was produced with a batch fermentor under agitation (500 rpm) and forced aeration (5 liters/min) in Casamino Acids yeast extract medium containing 0.2% glucose. The pH varied from 7.2 to 7.8. The maximum amount ...

journal_title：Infection and immunity

authors： Lallier R,Lariviere S,St-Pierre S

更新日期：1980-05-01 00:00:00

abstract：:The ApxIIA protein secreted from Actinobacillus pleuropneumoniae is both hemolytic and cytotoxic. However, when the cloned apxII operon is expressed in Escherichia coli, two forms of the ApxIIA protein can be recovered. Toxin which remains intracellular has hemolytic and cytotoxic activities, while toxin that is secre...

journal_title：Infection and immunity

authors： Tu AH,Hausler C,Young R,Struck DK

更新日期：1994-05-01 00:00:00

abstract：:Mycobacterium tuberculosis grows within the phagocytic vacuoles of macrophages, where it encounters a moderately acidic and possibly nutrient-restricted environment. Other mycobacterial species encounter acidic conditions in soil and aquatic environments. We have evaluated the influence of pH and divalent cation level...

journal_title：Infection and immunity

authors： Piddington DL,Kashkouli A,Buchmeier NA

更新日期：2000-08-01 00:00:00

abstract：:The she gene of Shigella flexneri 2a, which also harbors the internal enterotoxin genes set1A and set1B (F. R. Noriega, GenBank accession no. U35656, 1995) encodes a homolog of the virulence-related immunoglobulin A (IgA) protease-like family of secreted proteins, Tsh, EspC, SepA, and Hap, from an avian pathogenic Esc...

journal_title：Infection and immunity

authors： Rajakumar K,Sasakawa C,Adler B

更新日期：1997-11-01 00:00:00

abstract：:Our previous work suggests that one mechanism through which connective tissue breakdown might occur in periodontal diseases is the production of metalloproteinases, including collagenase, by gingival fibroblasts. In this study we investigated whether highly purified preparations of lipopolysaccharide (LPS) and lipotei...

journal_title：Infection and immunity

authors： Heath JK,Atkinson SJ,Hembry RM,Reynolds JJ,Meikle MC

更新日期：1987-09-01 00:00:00

abstract：:Live attenuated bacteria hold great promise as multivalent mucosal vaccines against a variety of pathogens. A major challenge of this approach has been the successful delivery of sufficient amounts of vaccine antigens to adequately prime the immune system without overattenuating the live vaccine. Here we used a live a...

journal_title：Infection and immunity

authors： Galen JE,Wang JY,Carrasco JA,Lloyd SA,Mellado-Sanchez G,Diaz-McNair J,Franco O,Buskirk AD,Nataro JP,Pasetti MF

更新日期：2015-01-01 00:00:00

abstract：:The objective of this research was to determine whether gram-negative bacteria frequently isolated from periodontally diseased sites contained polyclonal B-cell activators. Polyclonal B-cell activation, which results in nonspecific activation of multiple B-cell clones was analyzed by a hemolysis-in-gel assay designed ...

journal_title：Infection and immunity

authors： Bick PH,Carpenter AB,Holdeman LV,Miller GA,Ranney RR,Palcanis KG,Tew JG

更新日期：1981-10-01 00:00:00

abstract：:Monoclonal antibody WM-25 inhibited the in vitro growth of 13 F38 isolates from goats with contagious caprine pleuropneumonia but not 7 heterologous mycoplasma isolates representing four different species. In contrast to results with polyclonal antisera, growth inhibition by monoclonal antibody WM-25 was specific for ...

journal_title：Infection and immunity

authors： Rurangirwa FR,McGuire TC,Musoke AJ,Kibor A

更新日期：1987-12-01 00:00:00

abstract：:An immunogenic aminopeptidase was purified from Brucella melitensis strain VTRM1. The purification procedure consisted of ammonium sulfate fractionation and three chromatographic steps. This procedure resulted in a yield of 29% and a 144-fold increase in specific activity. The aminopeptidase appeared to be a monomeric...

journal_title：Infection and immunity

authors： Contreras-Rodriguez A,Ramirez-Zavala B,Contreras A,Schurig GG,Sriranganathan N,Lopez-Merino A

更新日期：2003-09-01 00:00:00

abstract：:In this analysis we have examined in detail the effects of low concentrations of zinc on the growth and dimorphism of Candida albicans. Evidence is presented that micromolar concentrations of zinc added to growth cultures grown at 25 degrees C (i) cause a twofold increase in the final concentration of spheres at satio...

journal_title：Infection and immunity

authors： Bedell GW,Soll DR

更新日期：1979-10-01 00:00:00

abstract：:Ingestion of 14C-amino acid-labeled Chlamydia psittaci (6BC) by mouse fibroblasts (L cells) was inhibited when the host cells were incubated for 30 min at 37 degrees C in Earle salts containing 10 mug of crystalline trypsin per ml. Tryptic digestion also inhibited the ingestion of 1-mum polystrene latex beads. Trypsin...

journal_title：Infection and immunity

authors： Byrne GI

更新日期：1976-09-01 00:00:00

abstract：:As part of a study of virulence gene regulation in Streptococcus pneumoniae, we have identified a gene encoding a homologue of the staphylococcal catabolite control protein CcpA in the pneumococcal genome sequence. The pneumococcal protein, designated RegM, has significant similarity to members of the LacI/GalR family...

journal_title：Infection and immunity

authors： Giammarinaro P,Paton JC

更新日期：2002-10-01 00:00:00

abstract：:Lipid compositions of 40 patient isolates of Mycobacterium tuberculosis derived from Madras, Burma, Rangoon, and East Africa were studied, and two major populations of tubercle bacilli were distinguished. Nearly all of the strains previously designated as attenuated for the guinea pig (D. A. Mitchison) are characteriz...

journal_title：Infection and immunity

authors： Goren MB,Brokl O,Schaefer WB

更新日期：1974-01-01 00:00:00

abstract：:Glucose metabolism and respiration of Candida albicans were compared under conditions which permitted either maximal filamentous or maximal yeast growth. Changes in metabolism were monitored by comparing the quantities of ethanol produced, CO2 evolved, and oxygen consumed. Filamenting cultures produced more ethanol an...

journal_title：Infection and immunity

authors： Land GA,McDonald WC,Stjernholm RL,Friedman L

更新日期：1975-07-01 00:00:00

abstract：:Elevated levels of immunoglobulin E anti-Candida antibodies were observed in the sera of patients with systemic and vaginal candidiasis and in cervicovaginal washings of the latter. ...

journal_title：Infection and immunity

authors： Mathur S,Goust JM,Horger EO 3rd,Fudenberg HH

更新日期：1977-10-01 00:00:00

abstract：:Fifteen clinical isolates of Trichomonas vaginalis were evaluated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis with transfer to nitrocellulose and by immunoblots probed with human sera. All T. vaginalis isolates showed similar banding patterns by Coomassie brilliant blue and silver staining of the elec...

journal_title：Infection and immunity

authors： Garber GE,Proctor EM,Bowie WR

更新日期：1986-01-01 00:00:00

abstract：:Pneumonic plague, caused by inhalation of Yersinia pestis, represents a major bioterrorism threat for which no vaccine is available. Based on the knowledge that genetic delivery of monoclonal antibodies (MAbs) with adenovirus (Ad) gene transfer vectors results in rapid, high-level antibody expression, we evaluated the...

journal_title：Infection and immunity

authors： Sofer-Podesta C,Ang J,Hackett NR,Senina S,Perlin D,Crystal RG,Boyer JL

更新日期：2009-04-01 00:00:00

abstract：:The effect of a standard regimen of cimetidine on the gastric flora of 20 male volunteers was studied in a double-blind manner and compared with the effects of a standard antacid regimen. Postprandial microbial titers in gastric aspirates were significantly higher at 4, 8, and 16 weeks of therapy in subjects taking an...

journal_title：Infection and immunity

authors： Snepar R,Poporad GA,Romano JM,Kobasa WD,Kaye D

更新日期：1982-05-01 00:00:00

abstract：:Strategies to limit complement deposition on Streptococcus pneumoniae are established as virulence features for invasive disease, but their role in respiratory tract infection requires further analysis. We evaluated complement C3 protein deposition on discordant S. pneumoniae isolates of the same serotype (6A) and the...

journal_title：Infection and immunity

authors： Sabharwal V,Ram S,Figueira M,Park IH,Pelton SI

更新日期：2009-03-01 00:00:00

abstract：:The chromosomal iroBCDEN gene cluster first described for Salmonella enterica is involved in the uptake of catecholate-type siderophore compounds. An orthologous gene cluster has recently been detected in Escherichia coli strains which cause extraintestinal disease. This E. coli iroBCDEN gene cluster has an impact on ...

journal_title：Infection and immunity

authors： Sorsa LJ,Dufke S,Heesemann J,Schubert S

更新日期：2003-06-01 00:00:00

abstract：:Neutrophil serine proteases cathepsin G (CG), neutrophil elastase (NE), and proteinase 3 (PR3) have recently been shown to contribute to killing of Streptococcus pneumoniae in vitro. However, their relevance in lung-protective immunity against different serotypes of S. pneumoniae in vivo has not been determined so far...

journal_title：Infection and immunity

authors： Hahn I,Klaus A,Janze AK,Steinwede K,Ding N,Bohling J,Brumshagen C,Serrano H,Gauthier F,Paton JC,Welte T,Maus UA

更新日期：2011-12-01 00:00:00

abstract：:We used the Salmonella typhi galactose epimerase (galE) mutant strain Ty21a, shown to be a safe, effective, living, attenuated oral typhoid vaccine, as a recipient for a recombinant plasmid containing the gene for production of the nontoxic B subunit of the heat-labile enterotoxin of Escherichia coli. The S. typhi der...

journal_title：Infection and immunity

authors： Clements JD,El-Morshidy S

更新日期：1984-11-01 00:00:00

abstract：:Cell-mediated immune (CMI) responses and tumor necrosis factor alpha (TNF-alpha) have been shown to be essential in acquired protection against Cryptococcus neoformans. Induction of a protective anticryptococcal CMI response includes increases in dendritic cells (DC) and activated CD4(+) T cells in draining lymph node...

journal_title：Infection and immunity

authors： Bauman SK,Huffnagle GB,Murphy JW

更新日期：2003-01-01 00:00:00

abstract：:Under certain circumstances, soluble antigens, particulate antigens, and/or microorganisms have been shown to bind to primate erythrocytes via complement receptor 1 (CR1) in the presence of specific antibodies and complement. This immune adherence reaction, specific for CR1, can lead to neutralization of antigens in t...

journal_title：Infection and immunity

authors： Powers JH,Buster BL,Reist CJ,Martin E,Bridges M,Sutherland WM,Taylor RP,Scheld WM

更新日期：1995-04-01 00:00:00