Pathogenicity of Escherichia coli O157:H7 in the intestines of neonatal calves.

abstract：:Culture filtrate from Mycobacterium tuberculosis contains protective antigens of relevance for the generation of a new antituberculosis vaccine. We have identified two previously uncharacterized M. tuberculosis proteins (TB7.3 and TB10.4) from the highly active low-mass fraction of culture filtrate. The molecules were...

journal_title：Infection and immunity

authors： Skjøt RL,Oettinger T,Rosenkrands I,Ravn P,Brock I,Jacobsen S,Andersen P

更新日期：2000-01-01 00:00:00

abstract：:We purified three proline-rich antimicrobial peptides from elastase-treated extracts of sheep and goat leukocytes and subjected two of them, OaBac5alpha and ChBac5, to detailed analysis. OaBac5alpha and ChBac5 were homologous to each other and to bovine Bac5. Both exhibited potent, broad-spectrum antimicrobial activit...

journal_title：Infection and immunity

authors： Shamova O,Brogden KA,Zhao C,Nguyen T,Kokryakov VN,Lehrer RI

更新日期：1999-08-01 00:00:00

abstract：:Bacteria exhibit extensive genetic heterogeneity within species. In many cases, these differences account for virulence properties unique to specific strains. Several such loci have been discovered in the genome of the type b serotype of Haemophilus influenzae, a human pathogen able to cause meningitis, pneumonia, and...

journal_title：Infection and immunity

authors： Bergman NH,Akerley BJ

更新日期：2003-03-01 00:00:00

abstract：:The protein P2 comprises a large proportion of the outer membrane of nontypable Haemophilus influenzae and functions as a porin. In view of the importance of the protein as a surface antigen, the present study was designed to purify and analyze P2 with particular emphasis on detection of antigenic determinants express...

journal_title：Infection and immunity

authors： Murphy TF,Bartos LC

更新日期：1988-05-01 00:00:00

abstract：:In order to further characterize human host defenses against Coccidioides immitis, extracts of this fungus were tested in vitro for their ability to attract polymorphonuclear leukocytes derived from peripheral blood of uninfected subjects. Soluble substances prepared from the mycelial (saprophytic) and spherule (tissu...

journal_title：Infection and immunity

authors： Galgiani JN,Isenberg RA,Stevens DA

更新日期：1978-09-01 00:00:00

abstract：:We compared the immune defense of mice with chronic granulomatous disease (CGD mice) with that of wild-type C57BL/6 mice for their response to Sporothrix schenckii. A subcutaneous injection of 5 x 10(4) CFU S. schenckii strain IFM41598 into CGD mice resulted in systemic infection and death within 84 days. In contrast,...

journal_title：Infection and immunity

authors： Kajiwara H,Saito M,Ohga S,Uenotsuchi T,Yoshida S

更新日期：2004-09-01 00:00:00

abstract：:We previously showed the requirement of both T cells and gamma interferon (IFN-gamma)-producing non-T cells for the genetic resistance of BALB/c mice to the development of toxoplasmic encephalitis (TE). In order to define the role of IFN-gamma production and the perforin-mediated cytotoxicity of T cells in this resist...

journal_title：Infection and immunity

authors： Wang X,Kang H,Kikuchi T,Suzuki Y

更新日期：2004-08-01 00:00:00

abstract：:An improved enterocyte adhesion assay has been used to examine a collection of 44 strains of enterotoxigenic Escherichia coli (ETEC) for their ability to adhere to the brush border of isolated human duodenal enterocytes. Fourteen strains showed good adhesion; in each case the ability to adhere correlated with the prod...

journal_title：Infection and immunity

authors： Knutton S,Lloyd DR,Candy DC,McNeish AS

更新日期：1985-06-01 00:00:00

abstract：:Endotoxin-resistant C3H/HeJ mice were used to test the hypothesis that a macrophage product, possibly interleukin-1, might mediate the depression of liver cytochrome P-450-dependent drug metabolism in endotoxin-treated mice. Depression of liver drug metabolism by endotoxin was observed in normal mice (C3H/HeN) but not...

journal_title：Infection and immunity

authors： Ghezzi P,Saccardo B,Villa P,Rossi V,Bianchi M,Dinarello CA

更新日期：1986-12-01 00:00:00

abstract：:A zone of extracellular digestion of the mucin layer around Candida albicans blastoconidia was observed by transmission electron microscopy in the jejunum of mice inoculated intragastrically (G. T. Cole, K. R. Seshan, L. M. Pope, and R. J. Yancey, J. Med. Vet. Mycol. 26:173-185, 1988). This observation prompted the hy...

journal_title：Infection and immunity

authors： Colina AR,Aumont F,Deslauriers N,Belhumeur P,de Repentigny L

更新日期：1996-11-01 00:00:00

abstract：:Protective immunity in mice to the infective third-stage larvae (L3) of Strongyloides stercoralis was shown to be dependent on immunoglobulin M (IgM), complement activation, and granulocytes. The objectives of the present study were to determine whether IgG was also a protective antibody isotype and to define the spec...

journal_title：Infection and immunity

authors： Ligas JA,Kerepesi LA,Galioto AM,Lustigman S,Nolan TJ,Schad GA,Abraham D

更新日期：2003-12-01 00:00:00

abstract：:Purification of the envelope antigen of Yersinia pestis EV with passive hemagglutination activity is described. The purification procedure consisted of pancreatin digestion, chromatography on human erythrocyte stroma set on Celite, and rechromatography on Sephadex G-200. Chemical, physical, and biological properties o...

journal_title：Infection and immunity

authors： Głosnicka R,Gruszkiewicz E

更新日期：1980-11-01 00:00:00

abstract：:The protection and immune response to infection caused by the parasite Schistosoma mansoni were studied by comparison of two murine irradiated-vaccine models. Mice were exposed from 1 to 4 times to infective-stage cercariae attenuated with either a moderate dose (15 kilorads) or a high dose (50 kilorads) of radiation....

journal_title：Infection and immunity

authors： Reynolds SR,Harn DA

更新日期：1992-01-01 00:00:00

abstract：:Hamster trachea organ cultres were shown to consume measurable amounts of oxygen when incubated in a closed micro-chamber. Several simple and complex media were evaluated, and the optimal system involved incubating 2 to 4 mg of tracheal tissue in Tyrodes balanced salt solution at 37 C for 60 min, with oxygen activity ...

journal_title：Infection and immunity

authors： Gabridge MG

更新日期：1975-09-01 00:00:00

abstract：:Phospholipase A2 and lysophospholipase activities were detected in the culture supernatant fluids of a virulent strain of Vibrio vulnificus. The phospholipase A2 was inactivated by heating at 56 degrees C for 30 min, had an apparent molecular weight of greater than or equal to 80,000 (estimated by gel filtration with ...

journal_title：Infection and immunity

authors： Testa J,Daniel LW,Kreger AS

更新日期：1984-08-01 00:00:00

abstract：:Interleukin-10 (IL-10)-producing B cells (B10 cells) play a critical role in the immune system balance by negatively regulating inflammatory responses. This study was conducted to determine the effect of local B10 cell induction on periodontal inflammation and bone loss in ligature-induced experimental periodontitis i...

journal_title：Infection and immunity

authors： Yu P,Hu Y,Liu Z,Kawai T,Taubman MA,Li W,Han X

更新日期：2016-12-29 00:00:00

abstract：:An Escherichia coli oligonucleotide microarray based on three sequenced genomes was validated for comparative genomic microarray hybridization and used to study the diversity of E. coli O157 isolates from human infections and food and animal sources. Among 26 test strains, 24 (including both Shiga toxin [Stx]-positive...

journal_title：Infection and immunity

authors： Wu G,Carter B,Mafura M,Liebana E,Woodward MJ,Anjum MF

更新日期：2008-02-01 00:00:00

abstract：:Chlamydia trachomatis is an obligate intracellular pathogen that causes sexually transmitted disease. In women, chlamydial infections may cause pelvic inflammatory disease (PID), ectopic pregnancy, and infertility. The role of antibodies in protection against a primary Chlamydia infection is unclear and was a focus of...

journal_title：Infection and immunity

authors： Shillova N,Howe SE,Hyseni B,Ridgell D,Fisher DJ,Konjufca V

更新日期：2020-12-15 00:00:00

abstract：:In vitro, Clostridium perfringens enterotoxin (CPE) binds to human ileal epithelium and induces morphological damage concurrently with reduced short-circuit current, transepithelial resistance, and net water absorption. CPE also binds to the human colon in vitro but causes only slight morphological and transport chang...

journal_title：Infection and immunity

authors： Fernández Miyakawa ME,Pistone Creydt V,Uzal FA,McClane BA,Ibarra C

更新日期：2005-12-01 00:00:00

abstract：:Antibody rises to various virus subcomponents were measured by enzyme-linked immunosorbent assay in the paired sera of volunteers experimentally infected with human coronavirus 229E group viruses. Most of the antibody made during infection was directed against the virus surface projections, with only small amounts of ...

journal_title：Infection and immunity

authors： Macnaughton MR,Hasony HJ,Madge MH,Reed SE

更新日期：1981-03-01 00:00:00

abstract：:Kinetoplastid membrane protein 11 (KMP-11) from Leishmania donovani is an abundant 11-kDa surface membrane glycoprotein. Lymph node cells from mice of six different H-2 haplotypes immunized with KMP-11 or with L. donovani promastigotes were stimulated to proliferate in vitro KMP-11. Primed purified T cells required an...

journal_title：Infection and immunity

authors： Tolson DL,Jardim A,Schnur LF,Stebeck C,Tuckey C,Beecroft RP,Teh HS,Olafson RW,Pearson TW

更新日期：1994-11-01 00:00:00

abstract：:Vibrio vulnificus causes rapidly progressing septicemia with an extremely high mortality rate (≥50%), even with aggressive antibiotic treatment. The bacteria secrete multifunctional autoprocessing repeats-in-toxin (MARTX) toxins, which are involved in the pathogenesis of Gram-negative Vibrio species. Recently, we repo...

journal_title：Infection and immunity

authors： Lee TH,Cha SS,Lee CS,Rhee JH,Chung KM

更新日期：2014-11-01 00:00:00

abstract：:Cytokine gene expression in cells migrating in afferent and efferent intestinal lymph was monitored for extended time periods in individual sheep experimentally infected with the nematode Trichostrongylus colubriformis. Animals from stable selection lines with increased levels of either genetic resistance (R) or susce...

journal_title：Infection and immunity

authors： Pernthaner A,Cole SA,Morrison L,Hein WR

更新日期：2005-04-01 00:00:00

abstract：:Host resistance to African trypanosomiasis is partially dependent on an early and strong T-independent B-cell response against the variant surface glycoprotein (VSG) coat expressed by trypanosomes. The repetitive array of surface epitopes displayed by a monotypic surface coat, in which identical VSG molecules are clos...

journal_title：Infection and immunity

authors： Dubois ME,Demick KP,Mansfield JM

更新日期：2005-05-01 00:00:00

abstract：:The properties of two candidate Salmonella typhi-based live oral typhoid vaccine strains, BRD691 (S. typhi Ty2 harboring mutations in aroA and aroC) and BRD1116 (S. typhi Ty2 harboring mutations in aroA, aroC, and htrA), were compared in a number of in vitro and in vivo assays. BRD1116 exhibited an increased susceptib...

journal_title：Infection and immunity

authors： Lowe DC,Savidge TC,Pickard D,Eckmann L,Kagnoff MF,Dougan G,Chatfield SN

更新日期：1999-02-01 00:00:00

abstract：:Loss of the actin filament capping protein CapG has no apparent effect on the phenotype of mice maintained under sterile conditions; however, bone marrow-derived macrophages from CapG(-/-) mice exhibited distinct motility defects. We examined the ability of CapG(-/-) mice to clear two intracellular bacteria, Listeria ...

journal_title：Infection and immunity

authors： Parikh SS,Litherland SA,Clare-Salzler MJ,Li W,Gulig PA,Southwick FS

更新日期：2003-11-01 00:00:00

abstract：:The compositions of lipopolysaccharides I and II, isolated from Coxiella burnetii phase I and pure phase II cells, respectively, showed drastic and clear-cut differences. Lipopolysaccharide II exhibited a comparatively simple composition. It contained, in addition to glucosamine (from lipid A) and a 2-keto-3-deoxyoctu...

journal_title：Infection and immunity

authors： Schramek S,Mayer H

更新日期：1982-10-01 00:00:00

abstract：:Vibrio cholerae O1 bacteria harvested directly from ligated or nonligated intestines of rabbits with experimental cholera expressed at least 7 to 8 novel, in vivo-specific cell envelope (env) proteins that were not found on vibrios after in vitro culture in various ordinary liquid media. At the same time, several of t...

journal_title：Infection and immunity

authors： Jonson G,Svennerholm AM,Holmgren J

更新日期：1989-06-01 00:00:00

abstract：:Apical membrane antigen 1 (AMA-1) is an invasion-related Plasmodium antigen that is expressed during both intracellular and extracellular asexual stages of the parasite's life cycle, making it an ideal target for induction of humoral and cellular immune responses that can protect against malaria. We show here that whe...

journal_title：Infection and immunity

authors： Bouillet LÉ,Dias MO,Dorigo NA,Moura AD,Russell B,Nosten F,Renia L,Braga EM,Gazzinelli RT,Rodrigues MM,Soares IS,Bruna-Romero O

更新日期：2011-09-01 00:00:00

abstract：:The combining sites of type 1 fimbrial lectins of various species of enterobacteria were studied by measuring the inhibitory activity of linear and branched oligosaccharides and several glycosides of D-mannose on the agglutination of yeast cells by the organisms. The results showed that all five strains of Escherichia...

journal_title：Infection and immunity

authors： Firon N,Ofek I,Sharon N

更新日期：1984-03-01 00:00:00