Gamma interferon production, but not perforin-mediated cytolytic activity, of T cells is required for prevention of toxoplasmic encephalitis in BALB/c mice genetically resistant to the disease.

abstract：:Mutation of sarA resulted in a reduced capacity to form a biofilm in six of the eight Staphylococcus aureus strains we tested (UAMS-1, UAMS-601, SA113, SC-01, S6C, and DB). The exceptions were Newman, which formed a poor biofilm under all conditions, and RN6390, which consistently formed a biofilm only after mutation ...

journal_title：Infection and immunity

authors： Beenken KE,Blevins JS,Smeltzer MS

更新日期：2003-07-01 00:00:00

abstract：:Female C57BL/6J mice were infected with Trypanosoma cruzi and subsequently given macrophages or lymphocytes from syngeneic donors which had recovered from the acute infection. Mice which received immune peritoneal macrophages, splenic lymphocytes, or lymph node lymphocytes developed lower mean parasitemias and cumulat...

journal_title：Infection and immunity

authors： Burgess DE,Hanson WL

更新日期：1979-09-01 00:00:00

abstract：:The hemolysins of Serpulina hyodysenteriae are active at 27 to 40 degrees C and pH 3 to 9 and are unaffected by enzymatic inhibitors. Pore formation was demonstrated by the inhibition of hemolysis with molecules of 2.0 to 2.3 nm in diameter and the release of 86rubidium from erythrocytes without hemoglobin release aft...

journal_title：Infection and immunity

authors： Hyatt DR,Joens LA

更新日期：1997-11-01 00:00:00

abstract：:Cytotoxic T lymphocytes (CTL) against herpes simplex virus (HSV) were induced in vitro from human peripheral blood lymphocytes by stimulation with HSV antigen. CTL generated by HSV type 1 (HSV-1) antigen stimulation killed not only HSV-1-infected target cells but also HSV type 2 (HSV-2)-infected target cells, though a...

journal_title：Infection and immunity

authors： Yasukawa M,Shiroguchi T,Kobayashi Y

更新日期：1983-04-01 00:00:00

abstract：:We investigated the effects of peripheral blood mononuclear cells expanded with irrelevant control and mycobacterial antigens on the intracellular growth of Mycobacterium bovis bacillus Calmette-Guérin (BCG) in human macrophages. More than 90% of the cells present after 1 week of in vitro expansion were CD3(+). T cell...

journal_title：Infection and immunity

authors： Worku S,Hoft DF

更新日期：2003-04-01 00:00:00

abstract：:Antibody responses against proteins located on the surface or in the apical organelles of merozoites are presumed to be important components of naturally acquired protective immune responses against the malaria parasite Plasmodium falciparum. However, many merozoite antigens are highly polymorphic, and antibodies indu...

journal_title：Infection and immunity

authors： Cortés A,Mellombo M,Masciantonio R,Murphy VJ,Reeder JC,Anders RF

更新日期：2005-01-01 00:00:00

abstract：:Protection against infection with virulent blood (trypomastigote) forms of Trypanosoma cruzi was accomplished in mice by immunization with culture (mainly epimastigote) forms killed by treatment with sodium perchlorate. Sodium chloride, used instead of sodium perchlorate, with all other conditions kept the same, faile...

journal_title：Infection and immunity

authors： Kierszenbaum F,Budzko DB

更新日期：1975-09-01 00:00:00

abstract：:We have studied polyacryl starch microparticles as an adjuvant in oral vaccination in mice. Secreted antigens from Salmonella enterica serovar Enteritidis were administered covalently conjugated to microparticles, or as free antigens, orally or intramuscularly and evaluated for their immunogenicity and ability to elic...

journal_title：Infection and immunity

authors： Strindelius L,Degling Wikingsson L,Sjöholm I

更新日期：2002-03-01 00:00:00

abstract：:The contribution of murine Toll-like receptors 2 and 4 (TLR2 and -4, respectively) to cytokine induction by heat-killed bacteria was analyzed in vitro and in vivo. Gram-negative bacteria induced cytokines primarily via TLR4; the contribution of TLR2 was only minor. Neither TLR4 nor, surprisingly, TLR2 was required in ...

journal_title：Infection and immunity

authors： Lembo A,Kalis C,Kirschning CJ,Mitolo V,Jirillo E,Wagner H,Galanos C,Freudenberg MA

更新日期：2003-10-01 00:00:00

abstract：:We used an in vitro opsonophagocytic killing assay to measure the functional activity of antibody directed at the mucoid exopolysaccharide (MEP) antigen expressed by Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. Rabbit antibodies raised to purified MEP were able to mediate phagocytic killing i...

journal_title：Infection and immunity

authors： Ames P,DesJardins D,Pier GB

更新日期：1985-08-01 00:00:00

abstract：:Streptococcus suis serotype 2 is a porcine and human pathogen with adhesive and invasive properties. In other streptococci, large surface-associated proteins (>100 kDa) of the MSCRAMM family (microbial surface components recognizing adhesive matrix molecules) are key players in interactions with host tissue. In this s...

journal_title：Infection and immunity

authors： Baums CG,Kaim U,Fulde M,Ramachandran G,Goethe R,Valentin-Weigand P

更新日期：2006-11-01 00:00:00

abstract：:A virus-specific cell surface antigen(s) was detected on mouse adenovirus-infected cells by the immunofluorescent antibody technique. It was demonstrated in infected cells regardless of the mouse strain or animal species used. It became detectable on the cell surface about 6 h postinfection and was demonstrated in 90%...

journal_title：Infection and immunity

authors： Inada T,Uetake H

更新日期：1977-10-01 00:00:00

abstract：:Porphyromonas gingivalis has been implicated as an etiologic agent of adult periodontitis. We have previously shown that P. gingivalis can degrade the epithelial cell-cell junction complexes, thus suggesting that this bacterium can invade the underlying connective tissues via a paracellular pathway. However, the preci...

journal_title：Infection and immunity

authors： Katz J,Yang QB,Zhang P,Potempa J,Travis J,Michalek SM,Balkovetz DF

更新日期：2002-05-01 00:00:00

abstract：:In an attempt to clarify the mechanism(s) of increased susceptibility to oral infection in diabetics, we examined the levels of salivary antibacterial factors, including lysozyme, lactoperoxidase, and lactoferrin, in diabetic hamsters whose condition was induced with streptozotocin. Saliva was collected from these ham...

journal_title：Infection and immunity

authors： Muratsu K,Morioka T

更新日期：1985-05-01 00:00:00

abstract：:The effects of passive administration of neutralizing monoclonal antibodies (MAB) to respiratory syncytial virus glycoproteins (GP90 and VP70) was evaluated in cotton rats challenged with respiratory syncytial virus. Animals injected with MAB to VP70 had lower mean viral titers in lung tissues than did controls (log10...

journal_title：Infection and immunity

authors： Walsh EE,Schlesinger JJ,Brandriss MW

更新日期：1984-02-01 00:00:00

abstract：:A purified A-antigen preparation of Blastomyces dermatitidis was determined to be composed of five major glycoprotein bands, visible with Coomassie blue and periodic acid-Schiff staining of polyacrylamide gels. At least 20 additional protein bands were detected by using a silver stain, which was 100 times more sensiti...

journal_title：Infection and immunity

authors： Young KD,Larsh HW

更新日期：1981-07-01 00:00:00

abstract：:Haemophilus ducreyi expresses 2 OmpA homologs, designated MOMP and OmpA2, whose genes are arranged in tandem on the chromosome. Northern blot analysis indicated that momp and ompA2 are transcribed independently. Sequences of the momp open reading frame (ORF) lacking the transcriptional start site were amplified by PCR...

journal_title：Infection and immunity

authors： Throm RE,Al-Tawfiq JA,Fortney KR,Katz BP,Hood AF,Slaughter CA,Hansen EJ,Spinola SM

更新日期：2000-05-01 00:00:00

abstract：:The typically recovered quantity of nontypeable Haemophilus influenzae (NTHi) bacteria in an ex vivo middle ear (ME) aspirate from the chinchilla model of experimental otitis media is insufficient for direct analysis of gene expression by microarray or of lipopolysaccharide glycoforms by mass spectrometry. This prompt...

journal_title：Infection and immunity

authors： Leroy M,Cabral H,Figueira M,Bouchet V,Huot H,Ram S,Pelton SI,Goldstein R

更新日期：2007-08-01 00:00:00

abstract：:Mutant analysis was used to identify Moraxella catarrhalis gene products necessary for biofilm development in a crystal violet-based assay involving 24-well tissue culture plates. The wild-type M. catarrhalis strains that formed the most extensive biofilms in this system proved to be refractory to transposon mutagenes...

journal_title：Infection and immunity

authors： Pearson MM,Laurence CA,Guinn SE,Hansen EJ

更新日期：2006-03-01 00:00:00

abstract：:The mucosal and systemic immune responses after primary and booster immunizations with two attenuated live oral vaccine strains derived from a noninvasive (Vibrio cholerae) and an invasive (Salmonella typhi) enteric pathogen were comparatively evaluated. Vaccination with S. typhi Ty21a elicited antibody-secreting cell...

journal_title：Infection and immunity

authors： Viret JF,Favre D,Wegmüller B,Herzog C,Que JU,Cryz SJ Jr,Lang AB

更新日期：1999-07-01 00:00:00

abstract：:An effective vaccine for Vibrio cholerae is not yet available for use in the developing world, where the burden of cholera disease is highest. Characterizing the proteins that are expressed by V. cholerae in the human host environment may provide insight into the pathogenesis of cholera and assist with the development...

journal_title：Infection and immunity

authors： LaRocque RC,Krastins B,Harris JB,Lebrun LM,Parker KC,Chase M,Ryan ET,Qadri F,Sarracino D,Calderwood SB

更新日期：2008-09-01 00:00:00

abstract：:Glycosylation of the flagellar core proteins (FlaBs) was detected in Treponema pallidum Nichols and in the type or reference strains of seven oral Treponema species. In several nonmotile strains of oral treponemes, the FlaBs were undetectable by both antibody and glycan staining. In contrast, a spontaneous low-motilit...

journal_title：Infection and immunity

authors： Wyss C

更新日期：1998-12-01 00:00:00

abstract：:Seven antigens of Borrelia hermsii, B. parkeri, and B. turicatae with isoelectric points in the range of 4.4 to 5.0 and molecular masses of 40 to 43 kilodaltons played a role in the relapse phenomenon of relapsing fever. Based upon location of the antigens in the outer envelope, the molecular weight, and Western blot ...

journal_title：Infection and immunity

authors： Kehl KS,Farmer SG,Komorowski RA,Knox KK

更新日期：1986-12-01 00:00:00

abstract：:A series of experiments was conducted to study the influence of embryonal bursectomy (EBX) on the early and late pathogenesis of Marek's disease (MD). The early lytic infection in the lymphoid organs normally associated with oncogenic MD virus infection in intact chickens was not seen in EBX chickens. Therefore, the d...

journal_title：Infection and immunity

authors： Schat KA,Calnek BW,Fabricant J

更新日期：1981-01-01 00:00:00

abstract：:The target organs of infection in guinea pigs with asymptomatic acquired or congenital syphilis were identified by PCR and in some cases by rabbit infectivity test (RIT). The prevalence of Treponema pallidum DNA was examined in the following seven organs: the inguinal and mesenteric lymph nodes, spleen, liver, kidney,...

journal_title：Infection and immunity

authors： Wicher K,Abbruscato F,Wicher V,Baughn R,Noordhoek GT

更新日期：1996-08-01 00:00:00

abstract：:We used the Salmonella typhi galactose epimerase (galE) mutant strain Ty21a, shown to be a safe, effective, living, attenuated oral typhoid vaccine, as a recipient for a recombinant plasmid containing the gene for production of the nontoxic B subunit of the heat-labile enterotoxin of Escherichia coli. The S. typhi der...

journal_title：Infection and immunity

authors： Clements JD,El-Morshidy S

更新日期：1984-11-01 00:00:00

abstract：:As part of a study of virulence gene regulation in Streptococcus pneumoniae, we have identified a gene encoding a homologue of the staphylococcal catabolite control protein CcpA in the pneumococcal genome sequence. The pneumococcal protein, designated RegM, has significant similarity to members of the LacI/GalR family...

journal_title：Infection and immunity

authors： Giammarinaro P,Paton JC

更新日期：2002-10-01 00:00:00

abstract：:A major problem in the study of chlamydial genital infections in animal models has been the use of varied doses of chlamydiae for infection in different laboratories. It is clearly desirable to use a dose which approximates that of natural sexual infection, but that dose to date has not been determined because of the ...

journal_title：Infection and immunity

authors： Rank RG,Bowlin AK,Reed RL,Darville T

更新日期：2003-11-01 00:00:00

abstract：:Cells of Candida albicans strain WO-1 and related strains switch frequently and reversibly between a white-colony-forming unit (white phase) and a gray-colony-forming unit (opaque phase). Cells in the budding white phase exhibit the usual smooth round phenotype observed in other C. albicans strains, but cells in the b...

journal_title：Infection and immunity

authors： Anderson J,Cundiff L,Schnars B,Gao MX,Mackenzie I,Soll DR

更新日期：1989-02-01 00:00:00

abstract：:Chlamydia trachomatis is an obligate intracellular pathogen that causes sexually transmitted disease. In women, chlamydial infections may cause pelvic inflammatory disease (PID), ectopic pregnancy, and infertility. The role of antibodies in protection against a primary Chlamydia infection is unclear and was a focus of...

journal_title：Infection and immunity

authors： Shillova N,Howe SE,Hyseni B,Ridgell D,Fisher DJ,Konjufca V

更新日期：2020-12-15 00:00:00