Analysis of the lytic activity of the Serpulina hyodysenteriae hemolysin.

abstract：:Infectious agents are often considered potential triggers of chronic inflammatory disease, including autoimmunity; however, direct evidence is usually lacking. Here we show that following control of acute infection of mice with the myotropic Colombiana strain of Trypanosoma cruzi, parasites persisted in tissue at low ...

journal_title：Infection and immunity

authors： Roffê E,Marino APMP,Weaver J,Wan W,de Araújo FF,Hoffman V,Santiago HC,Murphy PM

更新日期：2016-03-24 00:00:00

abstract：:Free lipid A of Bordetella pertussis, Neisseria meningitidis, and Escherichia coli lipopolysaccharide (LPS) was prepared by hydrolysis in acetate buffer (pH 4.5); in addition, lipid A from B. pertussis and E. coli was prepared by hydrolysis in mineral acid (HCl). The precipitates obtained were purified by extraction m...

journal_title：Infection and immunity

authors： Caroff M,Cavaillon JM,Fitting C,Haeffner-Cavaillon N

更新日期：1986-11-01 00:00:00

abstract：:Recently, our laboratory and others have demonstrated that human peripheral blood T and NK lymphocytes directly inhibit the growth of Cryptococcus neoformans. In this study, we further define the conditions under which lymphocyte-mediated fungistasis against C. neoformans occurs and examine whether mechanisms implicat...

journal_title：Infection and immunity

authors： Levitz SM,North EA,Dupont MP,Harrison TS

更新日期：1995-09-01 00:00:00

abstract：:Activation of macrophages was assessed in strains of mice inoculated intraperitoneally with 1,000 times the 50% lethal dose of Rickettsia akari. Macrophages from mice resistant to R. akari infection (C3H/HeN, C57BL/10J, and BALB/cN) were nonspecifically tumoricidal 2 to 4 days after rickettsial inoculation. Moreover, ...

journal_title：Infection and immunity

authors： Nacy CA,Meltzer MS

更新日期：1982-06-01 00:00:00

abstract：:The structural gene of pneumolysin was randomly mutagenized. A screen, developed to identify mutants with reduced hemolytic activity, identified substitutions within the cysteine-containing region and also at residues toward the N terminus of the toxin. These are the first reported changes within the N-terminal region...

journal_title：Infection and immunity

authors： Hill J,Andrew PW,Mitchell TJ

更新日期：1994-02-01 00:00:00

abstract：:Rabbit synovial cells (SC), articular chondrocytes (AC), and epiphyseal (EC) chondrocytes were grown in vitro. A portion of the spectrum of human pathogenic viruses infective for the cells was determined. Responses of the cells to different viruses or a chemical inducer of interferon varied, with EC responding vigorou...

journal_title：Infection and immunity

authors： Craig CP,Gordon SL,Greer RB

更新日期：1973-09-01 00:00:00

abstract：:Classical and El Tor strains of Vibrio cholerae were examined for production of bacteriophage or bacteriophage-related material by electron microscopy of mitomycin C-induced cultures. The strains were also tested for pathogenicity by using the ligated ileal loops of adult rabbits. Of the 27 strains tested, 25 showed a...

journal_title：Infection and immunity

authors： Parker C,Richardson SH,Romig WR

更新日期：1970-04-01 00:00:00

abstract：:EspC is an autotransporter protein secreted by enteropathogenic Escherichia coli (EPEC). The pathogenic role of EspC in EPEC infection is unknown. We have shown that the purified EspC produces enterotoxicity and cytotoxicity; for the latter effect, EspC must be internalized. However, the internalization mechanism is u...

journal_title：Infection and immunity

authors： Vidal JE,Navarro-García F

更新日期：2006-04-01 00:00:00

abstract：:Accurate diagnosis and early treatment of tuberculosis (TB) and latent TB infection (LTBI) are vital to prevent and control TB. The lack of specific biomarkers hinders these efforts. This study's purpose was to screen immunological markers that discriminate Mycobacterium tuberculosis infection outcomes in a setting wh...

journal_title：Infection and immunity

authors： Teklu T,Kwon K,Wondale B,HaileMariam M,Zewude A,Medhin G,Legesse M,Pieper R,Ameni G

更新日期：2018-03-22 00:00:00

abstract：:The plasma level of the chemokine CCL3 is elevated in patients with chronic severe schistosomiasis mansoni. We have previously shown that CCL3(-/-) mice with experimental infection showed diminished pathology and worm burden compared to those of wild-type (WT) mice. To elucidate further the role of CC chemokines durin...

journal_title：Infection and immunity

authors： Souza AL,Souza PR,Pereira CA,Fernandes A,Guabiraba R,Russo RC,Vieira LQ,Corrêa A Jr,Teixeira MM,Negrão-Corrêa D

更新日期：2011-04-01 00:00:00

abstract：:Establishment and maintenance of chronic lung infections with mucoid Pseudomonas aeruginosa in patients with cystic fibrosis (CF) require that the bacteria avoid host defenses. Elaboration of the extracellular, O-acetylated mucoid exopolysaccharide, or alginate, is a major microbial factor in resistance to immune effe...

journal_title：Infection and immunity

authors： Pier GB,Coleman F,Grout M,Franklin M,Ohman DE

更新日期：2001-03-01 00:00:00

abstract：:Isoelectric focusing and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) with acrylamide copolymerized with gelatin (substrate-SDS-PAGE) were combined to evaluate the proteinases of both long-term-grown and fresh isolates of Trichomonas vaginalis. This two-dimensional substrate-SDS-PAGE resolved a...

journal_title：Infection and immunity

authors： Neale KA,Alderete JF

更新日期：1990-01-01 00:00:00

abstract：:Some strains of Streptococcus mutans were found to recognize and bind collagen type I. Binding of 125I-labeled collagen type I was specific in that collagen types I and II, but not unrelated proteins, were able to inhibit binding of the labeled ligand to bacteria. Collagen binding to S. mutans was partially reversible...

journal_title：Infection and immunity

authors： Switalski LM,Butcher WG,Caufield PC,Lantz MS

更新日期：1993-10-01 00:00:00

abstract：:Saccharomyces boulardii, a nonpathogenic yeast, is effective in treating some patients with Clostridium difficile diarrhea and colitis. We have previously reported that S. boulardii inhibits rat ileal secretion in response to C. difficile toxin A possibly by releasing a protease that digests the intestinal receptor fo...

journal_title：Infection and immunity

authors： Castagliuolo I,LaMont JT,Nikulasson ST,Pothoulakis C

更新日期：1996-12-01 00:00:00

abstract：:Neisseria meningitidis is a major cause of sepsis and meningitis but is also a common commensal, present in the nasopharynx of between 8 and 20% of healthy individuals. During carriage, the bacterium is found on the surface of the nasopharyngeal epithelium and in deeper tissues, while to develop disease the meningococ...

journal_title：Infection and immunity

authors： Sutherland TC,Quattroni P,Exley RM,Tang CM

更新日期：2010-09-01 00:00:00

abstract：:Legionnaires' disease is clinically manifested as severe pneumonia caused by Legionella pneumophila. However, the dendritic cell (DC)-centered immunological framework of the host defense against L. pneumophila has not been fully delineated. For this study, we focused on a potent chemoattractant for lymphocytes, fracta...

journal_title：Infection and immunity

authors： Kikuchi T,Andarini S,Xin H,Gomi K,Tokue Y,Saijo Y,Honjo T,Watanabe A,Nukiwa T

更新日期：2005-09-01 00:00:00

abstract：:Counts of acid-fast bacilli were made on homogenates of whole liver, whole spleen, and two femurs of CBA mice killed at various time intervals after intravenous infection with Mycobacterium lepraemurium. The growth curves so obtained showed that the bacillus multiplied faster in bone marrow than in liver or spleen. No...

journal_title：Infection and immunity

authors： Brown IN,Krenzien HN

更新日期：1976-02-01 00:00:00

abstract：:Candida-associated denture stomatitis (DS) is a persistent and chronic oral infection of the denture-bearing palatal mucosa. DS stems from the ability of the fungal opportunistic pathogen Candida albicans to adhere to denture material and invade palatal tissue. Although DS is the most prevalent form of oral candidiasi...

journal_title：Infection and immunity

authors： Sultan AS,Rizk AM,Vila T,Ji Y,Masri R,Jabra-Rizk MA

更新日期：2019-11-18 00:00:00

abstract：:The parameters of a persistent-state measles virus infection in BGM/MV cells were examined. The BGM/MV cell line was established by cocultivation of measles virus-infected primary C3H mouse brain cells with a stable line of African green monkey kidney cells (BGM). Initially, a morphologically mixed population of cells...

journal_title：Infection and immunity

authors： Menna JH,Collins AR,Flanagan TD

更新日期：1975-01-01 00:00:00

abstract：:Lipoprotein I (OprI) is one of the major proteins of the outer membrane of Pseudomonas aeruginosa. OprI is a candidate for a vaccine against P. aeruginosa, because it cross-reacts antigenically in all serotype strains of the International Antigenic Typing Scheme. We recently cloned and expressed the gene coding for Op...

journal_title：Infection and immunity

authors： Finke M,Duchêne M,Eckhardt A,Domdey H,von Specht BU

更新日期：1990-07-01 00:00:00

abstract：:Complement-containing immune complexes can be presented to phagocytes by human erythrocytes bearing complement receptor 1 (CR1). Although this has long been assumed to be a mechanism by which humans are able to protect themselves from "extracellular" bacteria such as pneumococci, there is little direct evidence. In th...

journal_title：Infection and immunity

authors： Li J,Wang JP,Ghiran I,Cerny A,Szalai AJ,Briles DE,Finberg RW

更新日期：2010-07-01 00:00:00

abstract：:A crude complex containing group C polysaccharide, outer membrane proteins, and lipopolysaccharide (LPS) was isolated from the cell-free culture liquid of Neisseria meningitidis serogroup C, serotype 2a. Group C polysaccharide and LPS were removed from this complex, resulting in an outer membrane complex and a purifie...

journal_title：Infection and immunity

authors： Beuvery EC,Miedema F,van Delft RW,Haverkamp J,Leussink AB,te Pas BJ,Teppema KS,Tiesjema RH

更新日期：1983-04-01 00:00:00

abstract：:The influence of D-alanine and carbohydrate substitution of lipoteichoic acids (LTAs) on the binding of antibody directed to the polyglycerol phosphate (PGP) portion was found to be at least partially dependent upon the mode of presentation of the antigen. There were greater differences in binding of anti-PGP immunogl...

journal_title：Infection and immunity

authors： Kessler RE,Thivierge BH

更新日期：1983-08-01 00:00:00

abstract：:Complement receptor type 3 (CR3) was initially described as an opsonic receptor. Subsequently, CR3-mediated lectin-sugar recognition mechanisms have been shown to play a major role in the nonopsonic phagocytosis of several pathogens, among them Mycobacterium tuberculosis. Little is known about the binding and signal t...

journal_title：Infection and immunity

authors： Le Cabec V,Cols C,Maridonneau-Parini I

更新日期：2000-08-01 00:00:00

abstract：:Many pathogenic Escherichia coli produce the toxin alpha-hemolysin (Hly), and lipopolysaccharide (LPS), interleukin-1 (IL-1), and tumor necrosis factor (TNF) have all been recognized as important effector molecules during infections by gram-negative organisms. Despite the characterization of many in vitro effects of h...

journal_title：Infection and immunity

authors： Gleason TG,Houlgrave CW,May AK,Crabtree TD,Sawyer RG,Denham W,Norman JG,Pruett TL

更新日期：1998-09-01 00:00:00

abstract：:Herein we characterized various genetic markers and the biological behavior of a natural recombinant strain of Toxoplasma gondii (P-Br). From nine genetic markers analyzed, three (B1, ROP1, and SAG1) and three (cS10-A6, GRA6, and SAG3) markers belong to parasites from the type I and type III lineages, respectively. Th...

journal_title：Infection and immunity

authors： Fux B,Rodrigues CV,Portela RW,Silva NM,Su C,Sibley D,Vitor RW,Gazzinelli RT

更新日期：2003-11-01 00:00:00

abstract：:The pac gene of the serotype c strain Streptococcus mutans MT8148 encodes a cell surface protein antigen (PAc) of approximate 190 kilodaltons. The serotype c strain S. mutans GS-5 does not produce the 190-kilodalton PAc but produces a lower-molecular-weight protein that reacts with anti-PAc serum. The SphI-BamHI fragm...

journal_title：Infection and immunity

authors： Koga T,Okahashi N,Takahashi I,Kanamoto T,Asakawa H,Iwaki M

更新日期：1990-02-01 00:00:00

abstract：:Viral hepatitis caused by infection with murine hepatitis virus strain A59 has been shown to affect the mitotic response after partial hepatectomy in mice. Normal mice showed a delayed response, whereas nude mice did not show any response, even 5 days after partial hepatectomy. ...

journal_title：Infection and immunity

authors： Carthew P

更新日期：1981-08-01 00:00:00

abstract：:Groups of female C57BL/6 and C3H/St mice were inoculated intraperitoneally (i.p.) with 10(9), 10(7), and 10(5) bacilli and into the right hind footpad with 10(7) and 10(5) bacilli of Mycobacterium lepraemurium. The incidence of death from leprosy and the mean survival time of leprous mice were recorded. In addition, t...

journal_title：Infection and immunity

authors： Turcotte R

更新日期：1980-06-01 00:00:00

abstract：:Rabbit endogenous pyrogens occurred in two forms. One was an apparently single protein with a pI of 7.3; the other was a family of proteins with pI values of 4.5 to 5.0. We selected two of the latter, with pI values of 4.6 and 4.72, as representative of the group and compared them with the pI 7.3 pyrogen. Antisera rai...

journal_title：Infection and immunity

authors： Murphy PA,Cebula TA,Levin J,Windle BE

更新日期：1981-10-01 00:00:00