Systemic Mycobacterium lepraemurium infection in mice: differences in doubling time in liver, spleen, and bone marrow, and a method for measuring the proportion of viable organisms in an inoculum.

abstract：:The ability of Toxoplasma gondii tachyzoites to differentiate into latent bradyzoite forms is essential for pathogenesis of clinical disease. We examined the effects of cyclic nucleotides on T. gondii bradyzoite differentiation in vitro. Differentiation of tachyzoites to bradyzoites was measured in an immunofluorescen...

journal_title：Infection and immunity

authors： Kirkman LA,Weiss LM,Kim K

更新日期：2001-01-01 00:00:00

abstract：:To elucidate the mechanism of the high incidence of lower respiratory tract infections in patients with diabetes mellitus, we investigated the kinetics of production of macrophage inflammatory protein 2 (MIP-2), an important mediator of lung neutrophil recruitment, using mice with streptozotocin-induced diabetes. Intr...

journal_title：Infection and immunity

authors： Amano H,Yamamoto H,Senba M,Oishi K,Suzuki S,Fukushima K,Mukaida N,Matsushima K,Eguchi K,Nagatake T

更新日期：2000-05-01 00:00:00

abstract：:Shiga-like toxins (SLTs), which are produced by certain strains of Escherichia coli, are composed of enzymatically active A and B subunit multimers responsible for the toxin's binding. We have previously purified large amounts of the SLT-I B subunit by using a hyperexpression vector in Vibrio cholerae under the contro...

journal_title：Infection and immunity

authors： Acheson DW,De Breucker SA,Jacewicz M,Lincicome LL,Donohue-Rolfe A,Kane AV,Keusch GT

更新日期：1995-01-01 00:00:00

abstract：:The major antigenic determinants of the lipoglycans from Acholeplasma granularum and Acholeplasma axanthum were found to be the oligosaccharide sequences Glcp(beta 1 leads to 2)-Glcp(alpha 1 leads to 4)-Glcp and Glcp(beta 1 leads to 2)-Glcp(beta 1 leads to 2)-Glcp, respectively. The disaccharides sophorose and maltose...

journal_title：Infection and immunity

authors： Al-Samarrai TH,Smith PF,Lynn RJ

更新日期：1983-05-01 00:00:00

abstract：:Hamster (Mesocricetus auratus) neutrophil granules contain at least four microbicidal peptides belonging to the defensin family. These compounds were purified from granule acid extracts by reverse-phase chromatography and termed HaNP-1 to -4 (hamster neutrophil peptide). HaNP-1 and HaNP-3 revealed the most bactericida...

journal_title：Infection and immunity

authors： Mak P,Wójcik K,Thogersen IB,Dubin A

更新日期：1996-11-01 00:00:00

abstract：:Six strains of Rickettsia rickettsii from Montana and North Carolina were examined in an effort to identify rickettsial constituents associated with virulence. Fever responses, scrotal reactions, and mortalities of male guinea pigs inoculated intraperitoneally with 1,000 PFU of rickettsial strains revealed that the tw...

journal_title：Infection and immunity

authors： Anacker RL,Philip RN,Williams JC,List RH,Mann RE

更新日期：1984-06-01 00:00:00

abstract：:Our previous animal studies showed that maternal Porphyromonas gingivalis infection in a subcutaneous chamber is associated with hepatic and uterine translocation, as well as systemic induction of maternal inflammatory responses, both of which were associated with fetal growth restriction (FGR). However, P. gingivalis...

journal_title：Infection and immunity

authors： Lin D,Smith MA,Elter J,Champagne C,Downey CL,Beck J,Offenbacher S

更新日期：2003-09-01 00:00:00

abstract：:Pseudomonas aeruginosa invades various epithelial cell types in vitro and in vivo. The P. aeruginosa genome possesses a gene (flhA) which encodes a protein that is believed to be part of the export apparatus for flagellum assembly and which is homologous to invA of Salmonella spp. Because invA is required for invasion...

journal_title：Infection and immunity

authors： Fleiszig SM,Arora SK,Van R,Ramphal R

更新日期：2001-08-01 00:00:00

abstract：:The enzymes responsible for reducing H2O2 were surveyed in 49 strains of Leptospira by using semiquantitative assays for catalase and peroxidase. The survey revealed a differential distribution of catalase and peroxidase activities between the two leptospiral complexes. The pathogenic Leptospira interrogans strains ga...

journal_title：Infection and immunity

authors： Corin RE,Boggs E,Cox CD

更新日期：1978-12-01 00:00:00

abstract：:The comparative immunogenicity of the two cross-reacting group 6 pneumococcal capsular polysaccharides, type 6A(6) and type 6B(26), was studied with hyperimmune rabbit typing antisera and with sera from adult volunteers injected with polyvalent pneumococcal vaccines containing either 50 mug of type 6A (U.S. designatio...

journal_title：Infection and immunity

authors： Robbins JB,Lee CJ,Rastogi SC,Schiffman G,Henrichsen J

更新日期：1979-12-01 00:00:00

abstract：:Changes in the structural components of the Streptococcus pyogenes membrane between exponential and early stationary phases of growth are reported. The overall protein composition ranged from 70 to 73% of the dry weight of the membranes, irrespective of the phase of growth from which they were isolated. Amino acid ana...

journal_title：Infection and immunity

authors： van de Rijn I,Kessler RE

更新日期：1979-12-01 00:00:00

abstract：:The adherence of Enterococcus faecalis strains to human T24 cells was examined by scanning electron microscopy. Five highly adhesive strains were identified from 30 strains isolated from the urine of patients with urinary tract infections. No efficiently adhesive strains were found among the 30 strains isolated from t...

journal_title：Infection and immunity

authors： Shiono A,Ike Y

更新日期：1999-04-01 00:00:00

abstract：:In previous work, we identified xanthine oxidase (XO) as an important enzyme in the interaction between the host and enteropathogenic Escherichia coli(EPEC) and Shiga-toxigenic E. coli(STEC). Many of the biological effects of XO were due to the hydrogen peroxide produced by the enzyme. We wondered, however, if uric ac...

journal_title：Infection and immunity

authors： Crane JK,Broome JE,Lis A

更新日期：2016-03-24 00:00:00

abstract：:A clone expressing a 35.5-kDa recombinant treponemal protein was isolated from a genomic DNA library constructed from Treponema pallidum street strain 14. Polyclonal antiserum raised against the recombinant protein reacted with a corresponding native protein of comparable size in T. pallidum that is specific to the pa...

journal_title：Infection and immunity

authors： Hubbard CL,Gherardini FC,Bassford PJ Jr,Stamm LV

更新日期：1991-04-01 00:00:00

abstract：:Interactions between Yersinia enterocolitica and rabbit ileal mucus were examined. Strains carrying the Yersinia virulence plasmid, pYV, adhered to crude mucus but not to intestinal luminal contents that had been immobilized on polystyrene. Using an Y. enterocolitica O:9 mutant in which the yadA gene (formerly called ...

journal_title：Infection and immunity

authors： Paerregaard A,Espersen F,Jensen OM,Skurnik M

更新日期：1991-01-01 00:00:00

abstract：:Total-cell DNA isolated from a highly virulent serotype Ic strain of a group B streptococcus was used to construct a gene bank with bacteriophage lambda L47.1 in Escherichia coli K-12. Recombinant phage plaques in the bank were immunoblotted by using anti-alpha- and anti-beta-specific antibodies directed towards the I...

journal_title：Infection and immunity

authors： Cleat PH,Timmis KN

更新日期：1987-05-01 00:00:00

abstract：:Synthetic oligosaccharides derived from the capsular polysaccharide (PRP) of Haemophilus influenzae type b were conjugated to carrier proteins via a thioether linkage. Conjugates were made of trimeric and tetrameric ribose-ribitol-phosphate and tetanus toxoid or diphtheria toxin. All conjugates elicited anti-PRP antib...

journal_title：Infection and immunity

authors： Peeters CC,Evenberg D,Hoogerhout P,Käyhty H,Saarinen L,van Boeckel CA,van der Marel GA,van Boom JH,Poolman JT

更新日期：1992-05-01 00:00:00

abstract：:Colostrum was collected and pooled from each of five cows in three experimental groups: group I cows received intramuscular and intramammary inoculations of adjuvanted modified live Ohio Agricultural Research and Development Center rotavirus vaccine; group II cows were injected intramuscularly with a commercial modifi...

journal_title：Infection and immunity

authors： Saif LJ,Redman DR,Smith KL,Theil KW

更新日期：1983-09-01 00:00:00

abstract：:Salmonella enterica serovars Typhimurium and Dublin lysed primary bovine alveolar macrophages and immortalized J774.2 macrophage-like cells in the absence of either the morphological changes or DNA fragmentation characteristic of apoptosis. Macrophage lysis was dependent on a subset of caspases and an intact sipB gene...

journal_title：Infection and immunity

authors： Watson PR,Gautier AV,Paulin SM,Bland AP,Jones PW,Wallis TS

更新日期：2000-06-01 00:00:00

abstract：:The effect of infection with low-virulence, tissue culture-propagated strains of reticuloendotheliosis virus (REV) on protective vaccinal immunity against Marek's disease (MD) lymphomas was investigated. Vaccinated chickens inoculated at hatching with greater than 10(4) focus-forming units of REV and challenged with M...

journal_title：Infection and immunity

authors： Witter RL,Lee LF,Bacon LD,Smith EJ

更新日期：1979-10-01 00:00:00

abstract：:Helicobacter pylori strains frequently express Lewis X (Le(x)) and/or Le(y) on their cell surfaces as constituents of the O antigens of their lipopolysaccharide molecules. To assess the effect of Le(x) and Le(y) expression on the ability of H. pylori to colonize the mouse stomach and to adhere to epithelial cells, iso...

journal_title：Infection and immunity

authors： Takata T,El-Omar E,Camorlinga M,Thompson SA,Minohara Y,Ernst PB,Blaser MJ

更新日期：2002-06-01 00:00:00

abstract：:The production and role of tumor necrosis factor alpha (TNF-alpha) in pneumococcal pneumonia were investigated in a mouse pneumonia model. When approximately 10(6) CFU of Streptococcus pneumoniae TUM19 were used to inoculate CBA/J mice intranasally, TNF-alpha levels in the lungs and serum began to increase from 1 and ...

journal_title：Infection and immunity

authors： Takashima K,Tateda K,Matsumoto T,Iizawa Y,Nakao M,Yamaguchi K

更新日期：1997-01-01 00:00:00

abstract：:Periodontitis is the inflammatory response in periodontal tissues elicited by bacterial colonization in periodontal pockets. In this response, pocket epithelial cells are the first cells to come into contact with bacteria. To elucidate this mechanism, we determined the adherence of the periodontopathic bacterium Eiken...

journal_title：Infection and immunity

authors： Yumoto H,Nakae H,Fujinaka K,Ebisu S,Matsuo T

更新日期：1999-01-01 00:00:00

abstract：:Detailed structural studies were undertaken on five isolates of bovine rotavirus which showed variability in the migration patterns of their genome segments on electrophoresis in polyacrylamide gels. The individual genome segments of each isolate were characterized by partial digestion of terminally radiolabeled RNA w...

journal_title：Infection and immunity

authors： Clarke IN,McCrae MA

更新日期：1982-05-01 00:00:00

abstract：:We studied the influence of staphylococcal toxic shock syndrome toxin 1 and streptococcal erythrogenic (pyrogenic) toxin A (ETA) on intact and digitonin-permeabilized human polymorphonuclear granulocytes (PMNs). As was shown by reversed-phase high-performance liquid chromatography analysis, toxic shock syndrome toxin ...

journal_title：Infection and immunity

authors： Hensler T,Köller M,Geoffroy C,Alouf JE,König W

更新日期：1993-03-01 00:00:00

abstract：:Protection against colibacillosis in neonatal piglets was obtained by immunization of pregnant dams with procholeragenoid. Procholeragenoid is a stable high-molecular-weight aggregate of cholera toxin formed during the heating of cholera toxin. Procholeragenoid retained approximately 1% of the toxicity of native toxin...

journal_title：Infection and immunity

authors： Fürer E,Cryz SJ Jr,Dorner F,Nicolet J,Wanner M,Germanier R

更新日期：1982-03-01 00:00:00

abstract：:The morphology and pathology of cultured mouse glomeruli were examined at the cellular and subcellular levels after infection with a physiological isotonic L-form of Streptococcus pyogenes type 12 or exposure to streptococcal lipoteichoic acid. These changes, as viewed by light microscopy, were identical regardless of...

journal_title：Infection and immunity

authors： Tomlinson K,Leon O,Panos C

更新日期：1983-12-01 00:00:00

abstract：:Cryptosporidial infections in severe combined immune deficient (SCID) mice produce a chronic disease state which in the later stages leads to extraintestinal involvement and hepatic dysfunction. To further characterize the infection dynamics in this model and monitor the changes in the hepatic system, a dose titration...

journal_title：Infection and immunity

authors： Mead JR,Ilksoy N,You X,Belenkaya Y,Arrowood MJ,Fallon MT,Schinazi RF

更新日期：1994-05-01 00:00:00

abstract：:The levels of protection found in vaccine studies of murine visceral leishmaniasis are significantly lower than for cutaneous leishmaniasis; whether this is due to the high-challenge murine model employed and/or is a consequence of differences required in tissue-specific local immune responses is not understood. Conse...

journal_title：Infection and immunity

authors： Ahmed S,Colmenares M,Soong L,Goldsmith-Pestana K,Munstermann L,Molina R,McMahon-Pratt D

更新日期：2003-01-01 00:00:00

abstract：:Neisseria gonorrhoeae is the causative agent of the sexually transmitted disease gonorrhea, and infection with this organism is typically associated with an intense inflammatory response. In many individuals, however, the infection is asymptomatic and can progress to serious secondary complications. The type IV pili o...

journal_title：Infection and immunity

authors： Plant LJ,Jonsson AB

更新日期：2006-01-01 00:00:00