Morphological changes and pathology of mouse glomeruli infected with a streptococcal L-form or exposed to lipoteichoic acid.

abstract：:We developed an efficient electrotransformation system for the pathogenic fungus Histoplasma capsulatum and used it to examine the effects of features of the transforming DNA on transformation efficiency and fate of the transforming DNA and to demonstrate fungal expression of two recombinant Escherichia coli genes, hp...

journal_title：Infection and immunity

authors： Woods JP,Heinecke EL,Goldman WE

更新日期：1998-04-01 00:00:00

abstract：:Cells of several strains of Streptococcus gordonii attached in much higher numbers to experimental pellicles formed from samples of submandibular or parotid saliva on hydroxyapatite (HA) beads than to buffer controls. The nature of the salivary components responsible were investigated by preparing experimental pellicl...

journal_title：Infection and immunity

authors： Gibbons RJ,Hay DI,Schlesinger DH

更新日期：1991-09-01 00:00:00

abstract：:This study was undertaken to ascertain the relationship between complement-derived chemotactic factors and complement component 1 inactivator (C1INA) enhancement of neutrophil chemotaxis. Studies were also designed to determine whether the C1s- reactive or binding site on C1INA was functional in altering chemotactic r...

journal_title：Infection and immunity

authors： Patrick RA,Hollers JC,Liu DY,Giese BH,Smith CW

更新日期：1980-06-01 00:00:00

abstract：:Outer surface protein A (OspA) of the Lyme disease spirochete is primarily produced in the tick vector. OspA, which is a receptor for attaching spirochetes to the tick gut, is down regulated as the spirochetes leave the tick and enter the mammalian host. Although OspA is not a major antigen produced in the mammal, the...

journal_title：Infection and immunity

authors： Strother KO,Hodzic E,Barthold SW,de Silva AM

更新日期：2007-06-01 00:00:00

abstract：:Filifactor alocis is a recently recognized periodontal pathogen; however, little is known regarding its interactions with the immune system. As the first-responder phagocytic cells, neutrophils are recruited in large numbers to the periodontal pocket, where they play a crucial role in the innate defense of the periodo...

journal_title：Infection and immunity

authors： Armstrong CL,Miralda I,Neff AC,Tian S,Vashishta A,Perez L,Le J,Lamont RJ,Uriarte SM

更新日期：2016-11-18 00:00:00

abstract：:Chlamydia pneumoniae is a human respiratory pathogen. Unlike the other two Chlamydia species, no species-specific antigen has been defined for C. pneumoniae. An immunoreactive clone containing a 0.8-kb fragment was isolated from a C. pneumoniae (AR-39) genomic library by using anti-C. pneumoniae rabbit immune serum. B...

journal_title：Infection and immunity

authors： Perez Melgosa M,Kuo CC,Campbell LA

更新日期：1994-03-01 00:00:00

abstract：:In this study we demonstrate the capability of Chlamydia trachomatis to infect cultured human mesothelial cell (MC) monolayers and to induce the production of the proinflammatory cytokines interleukin 1beta (IL-1beta) and IL-8. Seventy-two hours after initial infection, both the procoagulant activity of MC and the act...

journal_title：Infection and immunity

authors： van Westreenen M,Pronk A,Diepersloot RJ,de Groot PG,Leguit P

更新日期：1998-05-01 00:00:00

abstract：:The P2 porin protein is the most abundant protein in the outer membrane of Haemophilus influenzae type b (Hib). Biochemical and immunochemical techniques were used to characterize the P2 proteins from a number of different Hib strains. P2 proteins from Hib outer membrane vesicles were resolved by sodium dodecyl sulfat...

journal_title：Infection and immunity

authors： Hansen EJ,Pelzel SE,Orth K,Moomaw CR,Radolf JD,Slaughter CA

更新日期：1989-11-01 00:00:00

abstract：:The outer membrane proteins of Bordetella avium were examined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Sarkosyl-insoluble outer membrane protein-enriched profiles from 50 virulent B. avium isolates, containing major 21,000- and 37,000-molecular-weight proteins (21K and 37K proteins, respectively) ...

journal_title：Infection and immunity

authors： Leyh R,Griffith RW

更新日期：1992-03-01 00:00:00

abstract：:By using the powerful separation technique of capillary gas chromatography combined with the selectivity of mass spectrometric detection, muramic acid was not detectable in purified elementary bodies of Chlamydia psittaci Cal 10 (less than or equal to 0.006%) or C. trachomatis serovar E (less than or equal to 0.02%). ...

journal_title：Infection and immunity

authors： Fox A,Rogers JC,Gilbart J,Morgan S,Davis CH,Knight S,Wyrick PB

更新日期：1990-03-01 00:00:00

abstract：:Three monoclonal antibodies (MAbs), all of the immunoglobulin G1 subclass, were raised against Cryptococcus neoformans by using the technique of cyclophosphamide ablation of B-cell responses against shared epitopes of the cross-reactive fungus Trichosporon beigelii. MAb 3C2 was reactive against the encapsulated and no...

journal_title：Infection and immunity

authors： Hamilton AJ,Jeavons L,Hobby P,Hay RJ

更新日期：1992-01-01 00:00:00

abstract：:Immunization of monkeys with the 82-kDa rhoptry protein (p82) of Plasmodium falciparum can protect them against a lethal blood stage challenge, and monoclonal antibodies to p82 inhibit parasite growth in vitro. The role that a p82-specific immune response might play in human immunity to the parasite is not known. To d...

journal_title：Infection and immunity

authors： Howard RF,Jensen JB,Franklin HL

更新日期：1993-07-01 00:00:00

abstract：:Microsporidia are obligate intracellular parasites that are ubiquitous in nature and have been recognized as causing an important emerging disease among immunocompromised individuals. Limited knowledge exists about the immune response against these organisms, and virtually nothing is known about the receptors involved...

journal_title：Infection and immunity

authors： Fischer J,Suire C,Hale-Donze H

更新日期：2008-10-01 00:00:00

abstract：:The localization and population levels of the indigenous bacterial flora of conventional rats were investigated by cultural and histological techniques. Lactobacilli predominate in the stomach and upper part of the small intestine and associate with keratinized cells of the nonglandular portion of stomach. Mixtures of...

journal_title：Infection and immunity

authors： Morotomi M,Watanabe T,Suegara N,Kawai Y,Mutai M

更新日期：1975-05-01 00:00:00

abstract：:An immune response (fluorescent antibody to membrane antigen) was detected in guinea pigs inoculated with varicella-zoster virus (VZV) adapted to guinea pig embryonic cells, including the Oka vaccine strain, even when inoculation was by an external route, i.e., nasal or corneal. Live or UV-inactivated virus having the...

journal_title：Infection and immunity

authors： Matsunaga Y,Yamanishi K,Takahashi M

更新日期：1982-08-01 00:00:00

abstract：:The selC tRNA gene is a common site for the insertion of pathogenicity islands in a variety of bacterial enteric pathogens. We demonstrate here that Escherichia coli that produces Shiga toxin 2d and does not harbor the locus of enterocyte effacement (LEE) contains, instead, a novel genomic island. In one representativ...

journal_title：Infection and immunity

authors： Schmidt H,Zhang WL,Hemmrich U,Jelacic S,Brunder W,Tarr PI,Dobrindt U,Hacker J,Karch H

更新日期：2001-11-01 00:00:00

abstract：:CD14, the leukocyte receptor for lipopolysaccharide (LPS), is important in the response of human polymorphonuclear leukocytes (PMNs) to infection with gram-negative bacteria. The level of CD14 on the PMN surface increases after exposure to some inflammatory stimuli such as N-formyl-methionyl-leucyl-phenylalanine (fMLP...

journal_title：Infection and immunity

authors： Rodeberg DA,Morris RE,Babcock GF

更新日期：1997-11-01 00:00:00

abstract：:The role of CD19(+) CD5(+) and CD19(+) CD5(-) B cell subpopulations in the antibody response to pneumococcal capsular polysaccharides (caps-PSs) is controversial. In the present study, we evaluated the role of human CD19(+) CD5(+) and CD19(+) CD5(-) cell populations in the serotype-specific antibody response to caps-P...

journal_title：Infection and immunity

authors： Moens L,Verbinnen B,Covens K,Wuyts G,Johnson M,Roalfe L,Goldblatt D,Meyts I,Bossuyt X

更新日期：2015-07-01 00:00:00

abstract：:Citrobacter rodentium is an attaching and effacing pathogen which causes transmissible colonic hyperplasia in mice. Infection with C. rodentium serves as a model for infection of humans with enteropathogenic and enterohemorrhagic Escherichia coli. To identify novel colonization factors of C. rodentium, we screened a s...

journal_title：Infection and immunity

authors： Hart E,Yang J,Tauschek M,Kelly M,Wakefield MJ,Frankel G,Hartland EL,Robins-Browne RM

更新日期：2008-11-01 00:00:00

abstract：:Immunization with live Plasmodium sporozoites under chloroquine prophylaxis (Spz plus CQ) induces sterile immunity against sporozoite challenge in rodents and, more importantly, in humans. Full protection is obtained with substantially fewer parasites than with the classic immunization with radiation-attenuated sporoz...

journal_title：Infection and immunity

authors： Mauduit M,Tewari R,Depinay N,Kayibanda M,Lallemand E,Chavatte JM,Snounou G,Rénia L,Grüner AC

更新日期：2010-05-01 00:00:00

abstract：:At least five proteins are secreted extracellularly by enteropathogenic Escherichia coli (EPEC), a leading cause of infant diarrhea in developing countries. However only one, EspC, is known to be secreted independently of the type III secretion apparatus encoded by genes located within the 35.6-kb locus of enterocyte ...

journal_title：Infection and immunity

authors： Mellies JL,Navarro-Garcia F,Okeke I,Frederickson J,Nataro JP,Kaper JB

更新日期：2001-01-01 00:00:00

abstract：:Legionella pneumophila organisms are able to infect and multiply within the ciliated protozoan Tetrahymena pyriformis. This ability may be associated with virulence, because an attenuated strain of L. pneumophila fails to multiply within this protozoan, whereas a virulent strain increases 10,000-fold in number when co...

journal_title：Infection and immunity

authors： Fields BS,Barbaree JM,Shotts EB Jr,Feeley JC,Morrill WE,Sanden GN,Dykstra MJ

更新日期：1986-09-01 00:00:00

abstract：:Rabbits were immunized with the synthetic peptide EENVEHDA or (EENV)2, corresponding to a tandemly repeated sequence in the C-terminal part of the Plasmodium falciparum antigen Pf155/RESA, or with Escherichia coli-derived fusion proteins containing the corresponding repeats. For all sera, the capacity of the total imm...

journal_title：Infection and immunity

authors： Wåhlin B,Berzins K,Perlmann H,Anders RF,Perlmann P

更新日期：1990-09-01 00:00:00

abstract：:In vivo administration of bacterial lipopolysaccharide to mice induced DNA fragmentation in the thymus. Fragmented DNA was confirmed by agarose gel electrophoresis and laser flow cytometry. DNA fragmentation was predominantly detected in the thymus of young mice, while it was undetectable in the spleen, bone marrow, a...

journal_title：Infection and immunity

authors： Zhang YH,Takahashi K,Jiang GZ,Kawai M,Fukada M,Yokochi T

更新日期：1993-12-01 00:00:00

abstract：:We wished to find a simple, biologically relevant method to evaluate the virulence of dengue viruses for human beings. Since cells of mononuclear phagocyte lineage may be important sites of dengue infection in primates, we evaluated the permissiveness of these cells to dengue virus as a correlate of virus virulence. T...

journal_title：Infection and immunity

authors： Halstead SB,Tom MC,Elm JL Jr

更新日期：1981-01-01 00:00:00

abstract：:Herein we characterized various genetic markers and the biological behavior of a natural recombinant strain of Toxoplasma gondii (P-Br). From nine genetic markers analyzed, three (B1, ROP1, and SAG1) and three (cS10-A6, GRA6, and SAG3) markers belong to parasites from the type I and type III lineages, respectively. Th...

journal_title：Infection and immunity

authors： Fux B,Rodrigues CV,Portela RW,Silva NM,Su C,Sibley D,Vitor RW,Gazzinelli RT

更新日期：2003-11-01 00:00:00

abstract：:Clostridium botulinum neurotoxins (BoNTs) are the most toxic proteins for humans. The current clostridial-derived vaccines against BoNT intoxication have limitations including production and accessibility. Conditions were established to express the soluble receptor binding domain (heavy-chain receptor [HCR]) of BoNT s...

journal_title：Infection and immunity

authors： Baldwin MR,Tepp WH,Pier CL,Bradshaw M,Ho M,Wilson BA,Fritz RB,Johnson EA,Barbieri JT

更新日期：2005-10-01 00:00:00

abstract：:The American opossum is the only experimental animal that regularly develops bacterial endocarditis spontaneously. There was no relation between the ability of opossums to clear bacteria from the bloodstream and the subsequent development of endocarditis. ...

journal_title：Infection and immunity

authors： Musher DM,Richie Y

更新日期：1974-06-01 00:00:00

abstract：:Ehrlichia chaffeensis, a tick-transmitted obligate intracellular rickettsial agent, causes human monocytic ehrlichiosis. In recent reports, we described substantial advances in developing random and targeted gene disruption methods to investigate the functions of E. chaffeensis genes. We reported earlier that the Hima...

journal_title：Infection and immunity

authors： Wang Y,Nair ADS,Alhassan A,Jaworski DC,Liu H,Trinkl K,Hove P,Ganta CK,Burkhardt N,Munderloh UG,Ganta RR

更新日期：2020-09-18 00:00:00

abstract：:In Pseudomonas aeruginosa, the second messenger cyclic-di-GMP and Gac/Rsm signaling pathways are associated with the transition from acute to chronic infection. Therefore, identification of the molecular mechanisms that govern lifestyle choice in bacteria is very important. Here, we identified a novel cyclic-di-GMP mo...

journal_title：Infection and immunity

authors： Jiao H,Li F,Wang T,Yam JKH,Yang L,Liang H

更新日期：2021-01-19 00:00:00