Chlamydia trachomatis infection of human mesothelial cells alters proinflammatory, procoagulant, and fibrinolytic responses.

abstract：:Previous research in this laboratory, using photoactivatable radioiodinated lipopolysaccharide derivatized with sulfosuccinimidyl-2-(p-azidosalicylamide)-1,3'-dithiopropionate (125I-ASD-LPS), has resulted in the identification of a specific LPS receptor with a molecular mass of approximately 73 kDa on murine lymphocyt...

journal_title：Infection and immunity

authors： Halling JL,Hamill DR,Lei MG,Morrison DC

更新日期：1992-03-01 00:00:00

abstract：:The lipooligosaccharide (LOS) present in the outer membrane of Haemophilus ducreyi is likely a virulence factor for this sexually transmitted pathogen. An open reading frame in H. ducreyi 35000 was found to encode a predicted protein that had 87% identity with the protein product of the gmhA (isn) gene of Haemophilus ...

journal_title：Infection and immunity

authors： Bauer BA,Stevens MK,Hansen EJ

更新日期：1998-09-01 00:00:00

abstract：:Chemiluminescence of human alveolar macrophages (AM) was evaluated in vitro. Unstimulated AM generated chemiluminescence that remained constant during incubation. Addition of heat-killed Staphylococcus aureus 502A (HKB) or a chemical agent, phorbol myristate acetate, produced high rates of chemiluminescence that were ...

journal_title：Infection and immunity

authors： Beall GD,Repine JE,Hoidal JR,Rasp FL

更新日期：1977-07-01 00:00:00

abstract：:Helicobacter pylori mutants deficient in 6-phosphogluconate dehydratase (6PGD) were constructed. Colonization densities were lower and minimum infectious doses were higher for mutant strains than for wild-type strains. In spite of better colonization, however, wild-type strains did not displace the mutant in cocoloniz...

journal_title：Infection and immunity

authors： Wanken AE,Conway T,Eaton KA

更新日期：2003-05-01 00:00:00

abstract：:Cytoadherence-linked asexual gene 9 (Clag9), a conserved Plasmodium protein expressed during the asexual blood stages, is involved in the cytoadherence of infected red blood cells (RBCs) to the endothelial lining of blood vessels. Here, we show that Plasmodium falciparum Clag9 (PfClag9) is a component of the PfClag9-R...

journal_title：Infection and immunity

authors： Chourasia BK,Deshmukh A,Kaur I,Paul G,Panda A,Rathore S,Singh SK,Theisen M,Mohmmed A,Malhotra P

更新日期：2020-01-22 00:00:00

abstract：:Cells of Yersinia pestis strain EV76 are known to cease growth after a shift from 26 to 37 degrees C in neutral Ca2+-deficient medium; this effect is potentiated by Mg2+. With 2.5 mM Mg2+ and no added Ca2+, restriction was relaxed at elevated pH at which maximum cell yields occurred in the presence of 20 mM exogenous ...

journal_title：Infection and immunity

authors： Zahorchak RJ,Brubaker RR

更新日期：1982-12-01 00:00:00

abstract：:We used a murine model to determine whether chronic corticosteroid therapy has uniform effects on bacterial clearance processes in different tissues. After a 2-week regimen of oral prednisolone, Swiss Webster mice were challenged with Pseudomonas aeruginosa strain PAO1 or virulent derivatives of PAO1 (IP-8 and IT-10)....

journal_title：Infection and immunity

authors： Nugent KM,Cox CD,Pesanti EL

更新日期：1984-03-01 00:00:00

abstract：:Enteropathogenic strains of Yersinia enterocolitica harbor a virulence plasmid (70 kilobases) which specifies, at 37 degrees C, a calcium requirement for growth, autoagglutinability, resistance to the bactericidal activity of human serum, and the expression of some outer membrane proteins (OMPs). To map the genes enco...

journal_title：Infection and immunity

authors： Balligand G,Laroche Y,Cornelis G

更新日期：1985-06-01 00:00:00

abstract：:Experiments were performed to study the effect of antibody to Streptococcus mutans glucosyltransferase (GTF) on the implantation of these organisms in hamsters. Salivary (immunoglobulin A) and serum (immunoglobulin G) antibodies to GTF and GTF-inhibiting activity were elicited by injection of GTF in Freund complete ad...

journal_title：Infection and immunity

authors： Smith DJ,Taubman MA,Ebersole JL

更新日期：1982-08-01 00:00:00

abstract：:The unpredictable nature of bioterrorism and the absence of real-time detection systems have highlighted the need for an efficient postexposure therapy for Bacillus anthracis infection. One approach is passive immunization through the administration of antibodies that mitigate the biological action of anthrax toxin. W...

journal_title：Infection and immunity

authors： Albrecht MT,Li H,Williamson ED,LeButt CS,Flick-Smith HC,Quinn CP,Westra H,Galloway D,Mateczun A,Goldman S,Groen H,Baillie LW

更新日期：2007-11-01 00:00:00

abstract：:Streptococcal protective antigen (Spa) is a newly described surface protein of group A streptococci that was recently shown to evoke protective antibodies (J. B. Dale, E. Y. Chiang, S. Liu, H. S. Courtney, and D. L. Hasty, J. Clin. Investig. 103:1261--1268, 1999). In this study, we have determined the complete sequenc...

journal_title：Infection and immunity

authors： McLellan DG,Chiang EY,Courtney HS,Hasty DL,Wei SC,Hu MC,Walls MA,Bloom JJ,Dale JB

更新日期：2001-05-01 00:00:00

abstract：:Endocarditis was induced in the rabbit by the placement of a polyethylene catheter in the right heart. The catheter was filled with stable L-phase variants of Staphylococcus aureus to determine if the variant form would colonize the damaged endocardium and produce further tissue injury similar to that produced by the ...

journal_title：Infection and immunity

authors： Linnemann CC Jr,Watanakunakorn C,Bakie C

更新日期：1973-05-01 00:00:00

abstract：:Previously, in our laboratory, we established a two-chamber system to study translocation of Enterococcus faecalis across monolayers of polarized human colon carcinoma-derived T84 cells. By using the same system in the present study, we now show that disruption of gelE of strain OG1RF, which also has a polar effect on...

journal_title：Infection and immunity

authors： Zeng J,Teng F,Murray BE

更新日期：2005-03-01 00:00:00

abstract：:Candida albicans is a ubiquitous mucosal commensal that is normally prevented from causing acute or chronic invasive disease. Neutrophils contribute to protection in oral infection but exacerbate vulvovaginal candidiasis. To dissect the role of neutrophils during mucosal candidiasis, we took advantage of a new, transp...

journal_title：Infection and immunity

authors： Gratacap RL,Scherer AK,Seman BG,Wheeler RT

更新日期：2017-08-18 00:00:00

abstract：:Hemolytic-uremic syndrome (HUS) is a serious complication predominantly associated with infection by enterohemorrhagic Escherichia coli (EHEC), such as E. coli O157:H7. EHEC can produce Shiga toxin 1 (Stx1) and/or Shiga toxin 2 (Stx2), both of which are exotoxins comprised of active (A) and binding (B) subunits. In pi...

journal_title：Infection and immunity

authors： Mukherjee J,Chios K,Fishwild D,Hudson D,O'Donnell S,Rich SM,Donohue-Rolfe A,Tzipori S

更新日期：2002-02-01 00:00:00

abstract：:Although often considered a strict human pathogen, Streptococcus pneumoniae has been reported to infect and cause pneumonia in horses, although the pathology appears restricted compared to that of human infections. Here we report on the molecular characterization of a group of S. pneumoniae isolates obtained from hors...

journal_title：Infection and immunity

authors： Whatmore AM,King SJ,Doherty NC,Sturgeon D,Chanter N,Dowson CG

更新日期：1999-06-01 00:00:00

abstract：:Protection against colibacillosis in neonatal piglets was obtained by immunization of pregnant dams with procholeragenoid. Procholeragenoid is a stable high-molecular-weight aggregate of cholera toxin formed during the heating of cholera toxin. Procholeragenoid retained approximately 1% of the toxicity of native toxin...

journal_title：Infection and immunity

authors： Fürer E,Cryz SJ Jr,Dorner F,Nicolet J,Wanner M,Germanier R

更新日期：1982-03-01 00:00:00

abstract：:The interactions between Capnocytophaga ochracea ATCC 33596 and Streptococcus sanguis H1, Actinomyces naeslundii PK984, or Actinomyces israelii PK16 are dependent on specific recognitions between heat-sensitive adhesins on C. ochracea and heat-stable structures (probably carbohydrate-containing receptors) on the surfa...

journal_title：Infection and immunity

authors： Weiss EI,London J,Kolenbrander PE,Kagermeier AS,Andersen RN

更新日期：1987-05-01 00:00:00

abstract：:The leukotrienes and tumor necrosis factor (TNF) play an important role in the pathophysiology of septic shock, in which hypotension, leukopenia, thrombocytopenia, and hemoconcentration are observed. This study was performed to examine the effects of a 5-lipoxygenase inhibitor (AA-861), a selective leukotriene recepto...

journal_title：Infection and immunity

authors： Ogata M,Matsumoto T,Kamochi M,Yoshida SI,Mizuguchi Y,Shigematsu A

更新日期：1992-06-01 00:00:00

abstract：:A concentrated bacterial culture supernatant from the hemolytic Moraxella bovis strain UQV 148NF was used to immunize mice and generate monoclonal antibodies (MAbs). One, MAb G3/D7, neutralized the hemolytic activity of M. bovis and recognized a 94-kDa protein by Western blot analysis in hemolytic M. bovis strains rep...

journal_title：Infection and immunity

authors： Billson FM,Harbour C,Michalski WP,Tennent JM,Egerton JR,Hodgson JL

更新日期：2000-06-01 00:00:00

abstract：:Athymic BALB/c nude mice and euthymic BALB/c mice were infected with Rickettsia akari by the intraperitoneal route. The rickettsialpox infection was terminated in euthymic mice with only two intraperitoneal injections of the antibiotic oxytetracycline, whereas prolonged treatment was necessary to terminate the infecti...

journal_title：Infection and immunity

authors： Kenyon RH,Pedersen CE Jr

更新日期：1980-05-01 00:00:00

abstract：:We demonstrate that a mucoid, alginate-producing strain of Pseudomonas aeruginosa isolated from the lungs of a cystic fibrosis (CF) patient secretes multiple enzymes with nucleoside diphosphate kinase (Ndk), ATPase, adenylate kinase, 5'-nucleotidase, and ATP-modifying enzymatic activities. The secretion is triggered a...

journal_title：Infection and immunity

authors： Zaborina O,Misra N,Kostal J,Kamath S,Kapatral V,El-Idrissi ME,Prabhakar BS,Chakrabarty AM

更新日期：1999-10-01 00:00:00

abstract：:Malaria infection caused by Plasmodium parasites continues to cause enormous morbidity and mortality in areas where it is endemic, and there is no licensed vaccine capable of inducing sterile protection. Hyperimmunization with attenuated whole sporozoites can induce sterile protective immune responses targeting preery...

journal_title：Infection and immunity

authors： Billman ZP,Seilie AM,Murphy SC

更新日期：2016-07-21 00:00:00

abstract：:The genetics of resistance to a naturally occurring respiratory infection caused by Sendai virus was examined in F1, F2, and backcross progeny of resistant C57BL/6J and susceptible DBA/2J mice and in 25 recombinant inbred strains. An intranasal inoculum of 0.1 50% tissue culture infective dose (low dose) of Sendai vir...

journal_title：Infection and immunity

authors： Brownstein DG

更新日期：1983-07-01 00:00:00

abstract：:Once in the cytoplasm of mammalian cells, Shigella flexneri expresses a motile phenotype caused by polar directional assembly of actin. This process depends on accumulation of IcsA (VirG), a 120-kDa protein with ATPase activity, at the pole of the bacterium opposite to that at which ongoing septation occurs. IcsA is a...

journal_title：Infection and immunity

authors： d'Hauteville H,Dufourcq Lagelouse R,Nato F,Sansonetti PJ

更新日期：1996-02-01 00:00:00

abstract：:Experimental Helicobacter pylori infection was studied in Mongolian gerbils with fresh human isolates that carry or do not carry cagA (cagA-positive or cagA-negative, respectively), multiply passaged laboratory strains, wild-type strain G1.1, or isogenic ureA, cagA, or vacA mutants of G1.1. Animals were sacrificed 1 t...

journal_title：Infection and immunity

authors： Wirth HP,Beins MH,Yang M,Tham KT,Blaser MJ

更新日期：1998-10-01 00:00:00

abstract：:Inner ear dysfunction secondary to chronic otitis media (OM), including high-frequency sensorineural hearing loss or vertigo, is not uncommon. Although chronic middle ear inflammation is believed to cause inner ear dysfunction by entry of OM pathogen components or cytokines from the middle ear into the inner ear, the ...

journal_title：Infection and immunity

authors： Moon SK,Woo JI,Lee HY,Park R,Shimada J,Pan H,Gellibolian R,Lim DJ

更新日期：2007-07-01 00:00:00

abstract：:Streptococcus pneumoniae infection leads to multifold increases in sialyltransferase, galactosyltransferase, alpha 2-fucosyltransferase, and alpha 3-fucosyltransferase activity of rat liver. Such changes may reflect an increased demand for glycosylation of acute-phase proteins synthesized and secreted by the liver dur...

journal_title：Infection and immunity

authors： Canonico PG,Little JS,Powanda MC,Bostian KA,Beisel WR

更新日期：1980-07-01 00:00:00

abstract：:Immunization with live Plasmodium sporozoites under chloroquine prophylaxis (Spz plus CQ) induces sterile immunity against sporozoite challenge in rodents and, more importantly, in humans. Full protection is obtained with substantially fewer parasites than with the classic immunization with radiation-attenuated sporoz...

journal_title：Infection and immunity

authors： Mauduit M,Tewari R,Depinay N,Kayibanda M,Lallemand E,Chavatte JM,Snounou G,Rénia L,Grüner AC

更新日期：2010-05-01 00:00:00

abstract：:Acquired cellular immunity to infection with Mycobacterium tuberculosis is believed to reside in the capacity of mononuclear phagocytes of immunized animals to inhibit intracellular multiplication of the parasite. However, in macrophage tissue culture systems, it has been customary to employ streptomycin in the medium...

journal_title：Infection and immunity

authors： Patterson RJ,Youmans GP

更新日期：1970-01-01 00:00:00