Involvement of the Haemophilus ducreyi gmhA gene product in lipooligosaccharide expression and virulence.

abstract：:Antibodies induced in sera and saliva of rats and rabbits immunized with ribosomal preparations from Streptococcus mutans 6715 inhibited transport of glucose by the phosphotransferase system by greater than 60%, acid production from sucrose by greater than 95%, and growth of the homologous S. mutans by greater than 59...

journal_title：Infection and immunity

authors： Gregory RL,Michalek SM,Shechmeister IL,McGhee JR

更新日期：1984-07-01 00:00:00

abstract：:We identified a T-cell determinant of the 35-kDa antigen of Mycobacterium leprae which is discriminatory against cross-sensitization by its closely related homologue in Mycobacterium avium. From synthetic peptides covering the entire sequence, those with the highest affinity and permissive binding to purified HLA-DR m...

journal_title：Infection and immunity

authors： Wilkinson RJ,Wilkinson KA,Jurcevic S,Hills A,Sinha S,Sengupta U,Lockwood DN,Katoch K,Altman D,Ivanyi J

更新日期：1999-03-01 00:00:00

abstract：:Antigenic competition between bovine gamma globulin (BGG) and endotoxin from a smooth strain (S-ET) and a rough (R-ET) heptoseless mutant strain of Salmonella minnesota was studied in mice. Both endotoxins acted as adjuvants for enhancing the antibody response to BGG. However, other work showed that the R-ET had minim...

journal_title：Infection and immunity

authors： Leong DL,Rudbach JA

更新日期：1971-02-01 00:00:00

abstract：:This work evaluated the kinetics of events that occur in the placenta of Calomys callosus after Toxoplasma gondii infection. Animals on the first day of pregnancy (dop) and virgin nonpregnant females were perorally infected with 20 cysts of T. gondii strain ME49. After 100 days of infection, the virgin animals were ma...

journal_title：Infection and immunity

authors： Ferro EA,Silva DA,Bevilacqua E,Mineo JR

更新日期：2002-12-01 00:00:00

abstract：:Borrelia burgdorferi, the causative agent of Lyme disease, loses its ability to infect and cause disease in mammalian hosts after repeated in vitro passage. To identify proteins preferentially expressed by the low-passage strain and thus representing potential virulence factors, the polypeptide profiles of virulent, l...

journal_title：Infection and immunity

authors： Norris SJ,Carter CJ,Howell JK,Barbour AG

更新日期：1992-11-01 00:00:00

abstract：:Several strains of gram-negative bacteria (seven genera, eight species) isolated from patients with urinary tract infections were found to hydrolyze myeloma immunoglobulin A (IgA) protein. Human IgG and IgM and colostrum IgA were not degraded by these organisms. Examination of cleavage digests showed two fragments of ...

journal_title：Infection and immunity

authors： Milazzo FH,Delisle GJ

更新日期：1984-01-01 00:00:00

abstract：:The tetraspanins are a superfamily of transmembrane proteins with diverse functions and can form extended microdomains within the plasma membrane in conjunction with partner proteins, which probably includes receptors for bacterial adhesins. Neisseria meningitidis, the causative agent of meningococcal disease, attache...

journal_title：Infection and immunity

authors： Green LR,Monk PN,Partridge LJ,Morris P,Gorringe AR,Read RC

更新日期：2011-06-01 00:00:00

abstract：:For the first time, hepatitis A viral antigen (HAAg) was shown in liver biopsy tissue from a patient in the acute phase of hepatitis type A by light and electron microscopy, using the peroxidase-antibody technique. Under light microscopy, the staining for HAAg appeared as a fine, granular reaction product, scattered t...

journal_title：Infection and immunity

authors： Shimizu YK,Shikata T,Beninger PR,Sata M,Setoyama H,Abe H,Tanikawa K

更新日期：1982-04-01 00:00:00

abstract：:A cell wall complex has been isolated by gentle methods from both the medium supernatant fluid and whole organisms of Neissieria meningitidis cultures. The two types of preparations have been shown to be essentially identical on the basis of chemical composition, electron microscopy, and polyacrylamide gel electrophor...

journal_title：Infection and immunity

authors： Zollinger WD,Kasper DL,Veltri BJ,Artenstein MS

更新日期：1972-11-01 00:00:00

abstract：:Iron is an important element for the growth of microorganisms as well as in the defense of the host by serving as a catalyst for the generation of free radicals via the Fenton/Haber-Weiss reactions. The iron transporter natural resistance-associated macrophage protein 1 (Nramp1) confers resistance to the growth of a v...

journal_title：Infection and immunity

authors： Zhong W,Lafuse WP,Zwilling BS

更新日期：2001-11-01 00:00:00

abstract：:We have characterized the natural immune responses to the 19-kDa domain of merozoite surface protein 1 in individuals from an area of western Kenya in which malaria is holoendemic. We used the three known natural variant forms of the yeast-expressed recombinant 19-kDa fragment that are referred to as the E-KNG, Q-KNG,...

journal_title：Infection and immunity

authors： Shi YP,Sayed U,Qari SH,Roberts JM,Udhayakumar V,Oloo AJ,Hawley WA,Kaslow DC,Nahlen BL,Lal AA

更新日期：1996-07-01 00:00:00

abstract：:Previous attempts to induce mucosal antibodies in rhesus monkeys by enteric immunization have resulted in only modest and short-lived responses, dominated by immunoglobulin M (IgM) antibodies in the plasma. In this study, two groups of rhesus monkeys were immunized intranasally three times at 2-week intervals with a b...

journal_title：Infection and immunity

authors： Russell MW,Moldoveanu Z,White PL,Sibert GJ,Mestecky J,Michalek S M

更新日期：1996-04-01 00:00:00

abstract：:We have constructed an improved recombination-based in vivo expression technology (RIVET) and used it as a screening method to identify Vibrio cholerae genes that are transcriptionally induced during infection of infant mice. The improvements include the introduction of modified substrate cassettes for resolvase that ...

journal_title：Infection and immunity

authors： Osorio CG,Crawford JA,Michalski J,Martinez-Wilson H,Kaper JB,Camilli A

更新日期：2005-02-01 00:00:00

abstract：:Legionella pneumophila, the gram-negative agent of Legionnaires' disease, possesses type IV pili and a type II protein secretion (Lsp) system, both of which are dependent upon the PilD prepilin peptidase. By analyzing multiple pilD mutants and various types of Lsp mutants as well as performing trans-complementation of...

journal_title：Infection and immunity

authors： Rossier O,Starkenburg SR,Cianciotto NP

更新日期：2004-01-01 00:00:00

abstract：:We have previously determined that complement receptors on human mononuclear phagocytes and complement component C3 in nonimmune serum mediate phagocytosis of the intracellular bacterial pathogen Mycobacterium leprae, the agent of leprosy. We have also determined that C3 fixes selectively to the major surface glycolip...

journal_title：Infection and immunity

authors： Schlesinger LS,Horwitz MA

更新日期：1994-01-01 00:00:00

abstract：:In a mouse model of thermal injury, an increase in burn size produced a decrease in the ratio of Candida albicans cells adherent to the marginal zone to those adherent to the white pulp of the spleen, an increase in the number of Candida cells in the circulation and in the kidneys, and an increase in mortality. ...

journal_title：Infection and immunity

authors： Neely AN,Orloff MM,Holder IA,Healy DP

更新日期：1997-08-01 00:00:00

abstract：:The hallmarks of pulmonary Mycobacterium tuberculosis infection are lung granulomas. These organized structures are composed of host immune cells whose purpose is to contain or clear infection, creating a complex hub of immune and bacterial cell activity, as well as limiting pathology in the lungs. Yet, given cellular...

journal_title：Infection and immunity

authors： Wong EA,Joslyn L,Grant NL,Klein E,Lin PL,Kirschner DE,Flynn JL

更新日期：2018-08-22 00:00:00

abstract：:Coxiella burnetii is the causative agent of Q fever, a zoonotic disease that threatens both human and animal health. Due to the paucity of experimental animal models, little is known about how host factors interface with bacterial components and affect pathogenesis. Here, we used Drosophila melanogaster, in conjunctio...

journal_title：Infection and immunity

authors： Bastos RG,Howard ZP,Hiroyasu A,Goodman AG

更新日期：2017-06-20 00:00:00

abstract：:In nature, mixed Borrelia burgdorferi infections are common and possibly can be acquired by either superinfection or coinfection. Superinfection by heterologous B. burgdorferi strains has been established experimentally, although the ability of homologous B. burgdorferi clones to superinfect a host has not been studie...

journal_title：Infection and immunity

authors： Rogovskyy AS,Bankhead T

更新日期：2014-11-01 00:00:00

abstract：:The M1inv+ subclone of M1 group A streptococci that spread globally in the late 1980s and early 1990s was previously identified by restriction fragment length polymorphism (RFLP), M protein, and SpeA exotoxin sequence analyses. Strains representing this subclone were characterized with regard to carriage of bacterioph...

journal_title：Infection and immunity

authors： Cleary PP,LaPenta D,Vessela R,Lam H,Cue D

更新日期：1998-11-01 00:00:00

abstract：:Experiments were performed to investigate the usefulness of an enzyme-linked immunosorbent assay utilizing avidin-biotin interaction as a diagnostic tool for detection of Toxoplasma antigen in blood. The lower limit of sensitivity of the assay by this method was ca. 4 ng/ml, and standard assays provided a linear plot ...

journal_title：Infection and immunity

authors： Ise Y,Iida T,Sato K,Suzuki T,Shimada K,Nishioka K

更新日期：1985-04-01 00:00:00

abstract：:Members of our group reported recently that neisseria infection of human epithelial cells results in accelerated degradation of the major lysosomal integral membrane protein LAMP1 and that this is due to hydrolysis of this glycoprotein at its immunoglobulin A1 (IgA1)-like hinge by the neisseria type 2 IgA1 protease (L...

journal_title：Infection and immunity

authors： Ayala P,Lin L,Hopper S,Fukuda M,So M

更新日期：1998-10-01 00:00:00

abstract：:Commercial fluid used for peritoneal lavage in peritonitis and in peritoneal dialysis suppressed the activity of peripheral blood leukocytes as measured by chemiluminescence, phagocytosis, and bacterial killing. Suppression was found to be due to the low pH and high osmolality of the fluid. The pH was adjusted to noni...

journal_title：Infection and immunity

authors： Duwe AK,Vas SI,Weatherhead JW

更新日期：1981-07-01 00:00:00

abstract：:Immunity to pneumococcal colonization in mice by exposure to live or killed pneumococci has been shown to be antibody independent but dependent on CD4+ T cells. Here we show that intranasal immunization with pneumococcal proteins (pneumococcal surface protein C, adhesin A, and a pneumolysoid) can elicit a similar mech...

journal_title：Infection and immunity

authors： Basset A,Thompson CM,Hollingshead SK,Briles DE,Ades EW,Lipsitch M,Malley R

更新日期：2007-11-01 00:00:00

abstract：:A panel of monoclonal antibodies (MAbs) specific for the heat-stable enterotoxin (STh) of enterotoxigenic Escherichia coli was produced. All four MAbs (8G7, 53-4, 11C, and SH1) bound to native STh in an enzyme-linked immunosorbent assay to various degrees, with clone SH1 showing the best affinity. The MAbs were screen...

journal_title：Infection and immunity

authors： Takeda T,Nair GB,Suzuki K,Zhe HX,Yokoo Y,De Mol P,Hemelhof W,Butzler JP,Takeda Y,Shimonishi Y

更新日期：1993-01-01 00:00:00

abstract：:Infection of L cells with Chlamydia psittaci inhibited the burst of deoxyribonucleic acid synthesis that occurs when the host cells are released from a double thymidine block. ...

journal_title：Infection and immunity

authors： Tribby II,Moulder JW

更新日期：1971-02-01 00:00:00

abstract：:Lipopolysaccharides (LPS), either in the free form or complexed to CD14, a LPS receptor, are elicitors of the immune system. Lactoferrin (Lf), a LPS-chelating glycoprotein, protects animals against septic shock. Since optimal protection requires administration of Lf prior to lethal doses of LPS, we hypothesized that i...

journal_title：Infection and immunity

authors： Baveye S,Elass E,Fernig DG,Blanquart C,Mazurier J,Legrand D

更新日期：2000-12-01 00:00:00

abstract：:The macrophage has previously been implicated in contributing to the renal inflammation associated with hemolytic-uremic syndrome (HUS). However, there is currently no in vivo model detailing the contribution of the renal macrophage to the kidney disease associated with HUS. Therefore, renal macrophage recruitment and...

journal_title：Infection and immunity

authors： Keepers TR,Gross LK,Obrig TG

更新日期：2007-03-01 00:00:00

abstract：:Haemophilus somnus causes pneumonia, reproductive failure, infectious myocarditis, thrombotic meningoencephalitis, and other diseases in cattle. Although vasculitis is commonly seen as a result of systemic H. somnus infections, the pathogenesis of vascular damage is poorly characterized. In this study, we demonstrated...

journal_title：Infection and immunity

authors： Sylte MJ,Corbeil LB,Inzana TJ,Czuprynski CJ

更新日期：2001-03-01 00:00:00

abstract：:Mutant cultures that lacked the ability to produce filamentous hemagglutinin were obtained by UV irradiation of Bordetella pertussis strain 18-323. Various biological activities of these mutants were compared with those of the parent culture. It was found that the leukocytosis-promoting, histamine-sensitizing, and mou...

journal_title：Infection and immunity

authors： Watanabe M,Nakase Y

更新日期：1982-03-01 00:00:00