Characterization of lectinlike surface components on Capnocytophaga ochracea ATCC 33596 that mediate coaggregation with gram-positive oral bacteria.

Abstract:

:The interactions between Capnocytophaga ochracea ATCC 33596 and Streptococcus sanguis H1, Actinomyces naeslundii PK984, or Actinomyces israelii PK16 are dependent on specific recognitions between heat-sensitive adhesins on C. ochracea and heat-stable structures (probably carbohydrate-containing receptors) on the surfaces of these gram-positive coaggregation partners. The coaggregation of C. ochracea with each of these three organisms was inhibited by L-rhamnose and D-fucose and to a lesser extent by beta-methyl-galactoside. The reaction with S. sanguis was the most sensitive, while the coaggregation with A. israelii was the least sensitive and was only partially inhibited by each of the sugars that were considered to be effective inhibitors. A more effective inhibition of the coaggregation between C. ochracea and A. israelii was achieved by adding a combination of the 6-deoxysugars and N-acetylneuraminic acid. To further characterize the coaggregations, naturally occurring coaggregation-defective (Cog-) mutants of C. ochracea were obtained from several different selections. Three phenotypically distinct groups of mutants were were isolated. Type 1 mutants failed to coaggregate with S. sanguis only. Type 2 mutants lost ability to interact with both S. sanguis and A. naeslundii. Type 3 mutants failed to coaggregate with all three coaggregation partners. Characterization of the Cog- mutants by sugar inhibition studies made it possible to distinguish three classes of adhesin activity.

journal_name

Infect Immun

journal_title

Infection and immunity

authors

Weiss EI,London J,Kolenbrander PE,Kagermeier AS,Andersen RN

doi

10.1128/IAI.55.5.1198-1202.1987

subject

Has Abstract

pub_date

1987-05-01 00:00:00

pages

1198-202

issue

5

eissn

0019-9567

issn

1098-5522

journal_volume

55

pub_type

杂志文章
  • Localization of electron-dense tracers during entry of Rickettsia tsutsugamushi into polymorphonuclear leukocytes.

    abstract::The invasion of Rickettsia tsutsugamushi, Gilliam strain, into guinea pig polymorphonuclear leukocytes (PMNs) and the localization and distribution of tracers were followed during the process by electron microscopy. The seven tracers used were: cationized ferritin, ferritin, thorium dioxide (ThO2), carbon particles, l...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.30.1.231-243.1980

    authors: Rikihisa Y,Ito S

    更新日期:1980-10-01 00:00:00

  • Chemical analysis of changes in membrane composition during growth of Streptococcus pyogenes.

    abstract::Changes in the structural components of the Streptococcus pyogenes membrane between exponential and early stationary phases of growth are reported. The overall protein composition ranged from 70 to 73% of the dry weight of the membranes, irrespective of the phase of growth from which they were isolated. Amino acid ana...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.26.3.883-891.1979

    authors: van de Rijn I,Kessler RE

    更新日期:1979-12-01 00:00:00

  • Estimating the relative contributions of virulence factors for pathogenic microbes.

    abstract::Many pathogenic microbes have multiple virulence factors that can cause damage to the host and thus contribute to an overall virulence phenotype for that organism. Although current techniques are suitable for demonstrating that a particular microbial characteristic contributes to virulence, no formal approach for defi...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.74.3.1500-1504.2006

    authors: McClelland EE,Bernhardt P,Casadevall A

    更新日期:2006-03-01 00:00:00

  • Pyruvate formate lyase is required for pneumococcal fermentative metabolism and virulence.

    abstract::Knowledge of the in vivo physiology and metabolism of Streptococcus pneumoniae is limited, even though pneumococci rely on efficient acquisition and metabolism of the host nutrients for growth and survival. Because the nutrient-limited, hypoxic host tissues favor mixed-acid fermentation, we studied the role of the pne...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00178-09

    authors: Yesilkaya H,Spissu F,Carvalho SM,Terra VS,Homer KA,Benisty R,Porat N,Neves AR,Andrew PW

    更新日期:2009-12-01 00:00:00

  • Survival of Staphylococcus epidermidis in Fibroblasts and Osteoblasts.

    abstract::Staphylococcus epidermidis is a leading cause of infections associated with indwelling medical devices, including prosthetic joint infection. While biofilm formation is assumed to be the main mechanism underlying the chronic infections S. epidermidis causes, we hypothesized that S. epidermidis also evades immune killi...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00237-18

    authors: Perez K,Patel R

    更新日期:2018-09-21 00:00:00

  • Factors affecting colonization and dissemination of Candida albicans from the gastrointestinal tract of mice.

    abstract::Male ICR Swiss mice (2 to 3 months old) were fed Candida albicans in their drinking water for 3 days, followed by no treatment, antibiotics in their drinking water (daily), or immunosuppressants given by intraperitoneal injection (two to three times weekly) over a 3- to 4-week period. The organs of animals were proces...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.55.7.1558-1563.1987

    authors: Ekenna O,Sherertz RJ

    更新日期:1987-07-01 00:00:00

  • Complement receptor 1 expression on mouse erythrocytes mediates clearance of Streptococcus pneumoniae by immune adherence.

    abstract::Complement-containing immune complexes can be presented to phagocytes by human erythrocytes bearing complement receptor 1 (CR1). Although this has long been assumed to be a mechanism by which humans are able to protect themselves from "extracellular" bacteria such as pneumococci, there is little direct evidence. In th...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.01263-09

    authors: Li J,Wang JP,Ghiran I,Cerny A,Szalai AJ,Briles DE,Finberg RW

    更新日期:2010-07-01 00:00:00

  • Purification and characterization of the extracellular C3d-binding protein of Candida albicans.

    abstract::A C3d-binding glycoprotein was purified from the culture filtrate of Candida albicans by preparative isoelectric focusing. The protein possessed a pI of 3.9 to 4.1 and could inhibit rosetting of EAC3d (sheep erythrocytes conjugated to C3d) by pseudohyphae of C. albicans. When analyzed by polyacrylamide gel electrophor...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.58.2.309-314.1990

    authors: Saxena A,Calderone R

    更新日期:1990-02-01 00:00:00

  • Heterophil antigen in bovine sera detectable by immune adherence hemagglutination with infectious mononucleosis sera.

    abstract::Bovine sera for tissue culture use were shown to contain heterophil antigen of the Paul-Bunnell-Davidsohn type by immune adherence hemagglutination tests with sera from patients with infectious mononucleosis. The antibody titers observed were comparable to those determined by two other methods; i.e., the immune adhere...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.19.3.923-927.1978

    authors: Lennette ET,Henle G,Henle W,Horwitz CA

    更新日期:1978-03-01 00:00:00

  • Cell-mediated immunity to Bordetella pertussis: role of Th1 cells in bacterial clearance in a murine respiratory infection model.

    abstract::A murine respiratory infection model was used to study the mechanism of protective immunity to Bordetella pertussis. We found that nude mice, which are deficient in T cells, developed a persistent infection and failed to clear the bacteria after aerosol inoculation. In contrast, normal adult nonimmune mice cleared a r...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.61.2.399-410.1993

    authors: Mills KH,Barnard A,Watkins J,Redhead K

    更新日期:1993-02-01 00:00:00

  • Degradation of protease inhibitors, immunoglobulins, and other serum proteins by Serratia protease and its toxicity to fibroblast in culture.

    abstract::We investigated the effect of the extracellular protease of Serratia marcescens on human serum constituents such as immunoglobulins, fibronectin, alpha 1-protease inhibitor, alpha 2-macroglobulin, lysozyme, and transferrin. At a very low concentration of Serratia 56-kilodalton protease (56K protease), purified human p...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.53.3.522-529.1986

    authors: Molla A,Matsumoto K,Oyamada I,Katsuki T,Maeda H

    更新日期:1986-09-01 00:00:00

  • Downregulation of chicken interleukin-17 receptor A during Eimeria infection.

    abstract::Both interleukin-17A (IL-17A) and IL-17F are proinflammatory cytokines that have an important role in intestinal homeostasis via receptor signaling. These cytokines have been characterized in chickens, but very little is known about their receptors and their functional activity. We provide here the first description o...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.02141-14

    authors: Kim WH,Jeong J,Park AR,Yim D,Kim S,Chang HH,Yang SH,Kim DH,Lillehoj HS,Min W

    更新日期:2014-09-01 00:00:00

  • Effect of phenethyl alcohol on Staphylococcus aureus alpha-lysin production.

    abstract::Phenethyl alcohol, at the maximum concentration which did not inhibit growth (0.3% [vol/vol]), inhibited the production of alpha-lysin and exoproteases but not that of delta-lysin in Staphylococcus aureus Wood 46. The inhibition of alpha-lysin was reversible, and transient accumulation of cell-associated alpha-lysin o...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.47.1.112-117.1985

    authors: Lee KY,Birkbeck TH

    更新日期:1985-01-01 00:00:00

  • Immunostimulatory, but not antiendotoxin, activity of lipid X is due to small amounts of contaminating N,O-acylated disaccharide-1-phosphate: in vitro and in vivo reevaluation of the biological activity of synthetic lipid X.

    abstract::Lipid X, a precursor in the biosynthesis of lipid A, has been claimed to possess most of the immunostimulatory activity but none of the toxicity of endotoxin. However, recent work shows that synthetic lipid X can be contaminated with small amounts of N,O-acylated disaccharide-1-phosphate (H. Aschauer, A. Grob, J. Hild...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.59.7.2351-2358.1991

    authors: Lam C,Hildebrandt J,Schütze E,Rosenwirth B,Proctor RA,Liehl E,Stütz P

    更新日期:1991-07-01 00:00:00

  • High levels of susceptibility and T helper 2 response in MyD88-deficient mice infected with Leishmania major are interleukin-4 dependent.

    abstract::Myeloid differentiation protein 88 (MyD88) is a general adaptor for the signaling cascade through receptors of the Toll/IL-1R family. When infected with Leishmania major parasites, MyD88-deficient mice displayed a dramatically enhanced parasite burden in their tissues similar to that found in susceptible BALB/c mice. ...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/iai.71.12.7215-7218.2003

    authors: Debus A,Gläsner J,Röllinghoff M,Gessner A

    更新日期:2003-12-01 00:00:00

  • Antibody responses in adult volunteers to pneumococcal polysaccharide types 19F and 19A administered singly and in combination.

    abstract::The immunogenicity of the two major group 19 pneumococcal polysaccharides, types 19F and 19A, was studied in human volunteers. Antibody responses after vaccination with either 50 micrograms of type 19F polysaccharide, 50 micrograms of type 19A polysaccharide, or 25 micrograms of both polysaccharides premixed in a sing...

    journal_title:Infection and immunity

    pub_type: 临床试验,杂志文章

    doi:10.1128/IAI.36.3.1261-1262.1982

    authors: Penn RL,Lewin EB,Douglas RG Jr,Schiffman G,Lee CJ,Robbins JB

    更新日期:1982-06-01 00:00:00

  • Multiple antigen peptide vaccines against Plasmodium falciparum malaria.

    abstract::The multiple antigen peptide (MAP) approach is an effective method to chemically synthesize and deliver multiple T-cell and B-cell epitopes as the constituents of a single immunogen. Here we report on the design, chemical synthesis, and immunogenicity of three Plasmodium falciparum MAP vaccines that incorporated antig...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.00533-10

    authors: Mahajan B,Berzofsky JA,Boykins RA,Majam V,Zheng H,Chattopadhyay R,de la Vega P,Moch JK,Haynes JD,Belyakov IM,Nakhasi HL,Kumar S

    更新日期:2010-11-01 00:00:00

  • Construction and characterization of a potential live oral carrier-based vaccine against Vibrio cholerae O139.

    abstract::The rfb region from Vibrio cholerae O139 strain MO45 was cloned from cosmid gene banks established in Escherichia coli HB101, using an immunoblot assay for screening of the correct clones. Immunoblot analysis of lipopolysaccharide (LPS) preparations revealed the presence of two types of positive clones: (i) those expr...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.64.9.3565-3570.1996

    authors: Favre D,Cryz SJ Jr,Viret JF

    更新日期:1996-09-01 00:00:00

  • Impact of mosquito bites on asexual parasite density and gametocyte prevalence in asymptomatic chronic Plasmodium falciparum infections and correlation with IgE and IgG titers.

    abstract::An immunomodulatory role of arthropod saliva has been well documented, but evidence for an effect on Plasmodium sp. infectiousness remains controversial. Mosquito saliva may orient the immune response toward a Th2 profile, thereby priming a Th2 response against subsequent antigens, including Plasmodium. Orientation to...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.06414-11

    authors: Lawaly R,Konate L,Marrama L,Dia I,Diallo D,Diène Sarr F,Schneider BS,Casademont I,Diallo M,Brey PT,Sakuntabhai A,Mecheri S,Paul R

    更新日期:2012-06-01 00:00:00

  • A double, long polar fimbria mutant of Escherichia coli O157:H7 expresses Curli and exhibits reduced in vivo colonization.

    abstract::Escherichia coli O157:H7 causes food and waterborne enteric infections that can result in hemorrhagic colitis and life-threatening hemolytic uremic syndrome. Intimate adherence of the bacteria to intestinal epithelial cells is mediated by intimin, but E. coli O157:H7 also possess several other putative adhesins, inclu...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.05945-11

    authors: Lloyd SJ,Ritchie JM,Rojas-Lopez M,Blumentritt CA,Popov VL,Greenwich JL,Waldor MK,Torres AG

    更新日期:2012-03-01 00:00:00

  • Comparison of techniques for primary isolation of respiratory Mycoplasma pulmonis from rats.

    abstract::Studies were performed to determine the optimal sites for primary isolation of Mycoplasma pulmonis from the respiratory system of laboratory rats. In a preliminary study, a group of 42 rats was cultured for respiratory M. pulmonis at several sites. Tracheal washes yielded the highest number of positive cultures (61.9%...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.26.2.590-593.1979

    authors: Lentsch RH,Wagner JE,Owens DR

    更新日期:1979-11-01 00:00:00

  • Participation of complement in host defense against encapsulated Haemophilus influenzae types a, c, and d.

    abstract::Each of the serotypes of Haemophilus influenzae (types a to f) may colonize the respiratory tract of humans, but only type b strains commonly cause invasive systemic infections. To investigate the role of complement in immunity to encapsulated non-type b strains, rats were depleted of C3 with cobra venom factor and ch...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.35.3.759-763.1982

    authors: Corrall CJ,Winkelstein JA,Moxon ER

    更新日期:1982-03-01 00:00:00

  • Polyclonal B-cell activation induced by extracts of Gram-negative bacteria isolated from periodontally diseased sites.

    abstract::The objective of this research was to determine whether gram-negative bacteria frequently isolated from periodontally diseased sites contained polyclonal B-cell activators. Polyclonal B-cell activation, which results in nonspecific activation of multiple B-cell clones was analyzed by a hemolysis-in-gel assay designed ...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.34.1.43-49.1981

    authors: Bick PH,Carpenter AB,Holdeman LV,Miller GA,Ranney RR,Palcanis KG,Tew JG

    更新日期:1981-10-01 00:00:00

  • Toxic shock syndrome-associated staphylococcal and streptococcal pyrogenic toxins are potent inducers of tumor necrosis factor production.

    abstract::Toxic shock syndrome-associated staphylococcal and streptococcal exotoxins were tested for an ability to induce the production of tumor necrosis factor (TNF). Staphylococcal enterotoxins B and C1, along with streptococcal pyrogenic exotoxin A, all induced TNF production in a dose-dependent manner, with production peak...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.57.1.291-294.1989

    authors: Fast DJ,Schlievert PM,Nelson RD

    更新日期:1989-01-01 00:00:00

  • Production of Bacteriophage-Associated Materials by Vibrio cholerae: Possible Correlation with Pathogenicity.

    abstract::Classical and El Tor strains of Vibrio cholerae were examined for production of bacteriophage or bacteriophage-related material by electron microscopy of mitomycin C-induced cultures. The strains were also tested for pathogenicity by using the ligated ileal loops of adult rabbits. Of the 27 strains tested, 25 showed a...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.1.4.417-420.1970

    authors: Parker C,Richardson SH,Romig WR

    更新日期:1970-04-01 00:00:00

  • Copy number of pilus gene clusters in Haemophilus influenzae and variation in the hifE pilin gene.

    abstract::Brazilian purpuric fever (BPF)-associated Haemophilus influenzae biogroup aegyptius strain F3031 contains two identical copies of a five gene cluster (hifA to hifE) encoding pili similar to well-characterized Hif fimbriae of H. influenzae type b. HifE, the putative pilus tip adhesin of F3031, shares only 40% amino aci...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.66.4.1622-1631.1998

    authors: Read TD,Satola SW,Opdyke JA,Farley MM

    更新日期:1998-04-01 00:00:00

  • Quantitation of immunoglobulin-bearing lymphocytes and lymphocyte response to mitogens in horses persistently infected by equine infectious anemia virus.

    abstract::A defect in lymphocyte function could be responsible for persistent infection by the equine infectious anemia virus. The number of lymphocytes bearing surface immunoglobulin, as detected by immunofluorescence, and lymphocyte response to mitogens were the same in uninfected and equine infectious anemia-infected animals...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.8.4.679-682.1973

    authors: Banks KL,Henson JB

    更新日期:1973-10-01 00:00:00

  • Production of immunoglobulin M (IgM) autoantibodies to IgG in rabbits inoculated with Mycoplasma salivarium cells grown in medium supplemented with rabbit serum.

    abstract::Mycoplasma salivarium cells propagated in PPLO broth (Difco Laboratories, Detroit, Mich.) supplemented with rabbit serum (10% [vol/vol]) and harvested by centrifugation were shown to contain rabbit immunoglobulin G (IgG) (approximately 4 to 10% of total cell proteins) and to produce IgM autoantibodies to IgG when inoc...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.55.1.263-265.1987

    authors: Watanabe T,Shibata K,Hasegawa K

    更新日期:1987-01-01 00:00:00

  • Production of mouse lymphotoxin by phytohemagglutinin-stimulated spleen cells requires two cell fractions.

    abstract::The appearance of lymphotoxin in the culture fluid of phytohemagglutinin (PHA)-stimulated mouse spleen cells required two cell fractions that were separated by adherence to plastic. Upon stimulation with PHA, neither cell fraction alone produced significant amounts of lymphotoxin; however, when the cell fractions were...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.36.3.1028-1035.1982

    authors: Aksamit RR,Leonard EJ

    更新日期:1982-06-01 00:00:00

  • Mediation of immunity to Eimeria vermiformis in mice by L3T4+ T cells.

    abstract::Immunity to infection with Eimeria vermiformis was transferred in NIH mice by both the nylon wool-adherent (B-cell-enriched) and nonadherent (T-cell-enriched) fractions of lymphocytes (spleen and mesenteric lymph node) taken from infected donors. Transfer was more variable with the adherent fraction, and when contamin...

    journal_title:Infection and immunity

    pub_type: 杂志文章

    doi:10.1128/IAI.56.7.1760-1765.1988

    authors: Rose ME,Joysey HS,Hesketh P,Grencis RK,Wakelin D

    更新日期:1988-07-01 00:00:00