Quantitation of immunoglobulin-bearing lymphocytes and lymphocyte response to mitogens in horses persistently infected by equine infectious anemia virus.

abstract：:Representative strains of oral streptococci were tested for Fc immunoglobulin G (IgG) reactivity by two different techniques, agglutination of rabbit-IgG sensitized sheep erythrocytes and uptake of human and rabbit 125I-radiolabeled IgG. None of the S. mutans serotypes a through e reacted with the Fc region of either ...

journal_title：Infection and immunity

authors： Shea C,Ferretti JJ

更新日期：1981-12-01 00:00:00

abstract：:The type III secretion system (T3SS) of pathogenic bordetellae employs a self-associating tip complex protein Bsp22. This protein is immunogenic during infections by Bordetella bronchiseptica and could be used as a protective antigen to immunize mice against B. bronchiseptica challenge. Since low-passage clinical isol...

journal_title：Infection and immunity

authors： Villarino Romero R,Bibova I,Cerny O,Vecerek B,Wald T,Benada O,Zavadilova J,Osicka R,Sebo P

更新日期：2013-08-01 00:00:00

abstract：:Tuberculosis is rising in the developing world due to poor health care, human immunodeficiency virus type 1 infection, and the low protective efficacy of the Mycobacterium bovis BCG vaccine. A new vaccination strategy that could protect adults in the developing world from tuberculosis could have a huge impact on publi...

journal_title：Infection and immunity

authors： Williams A,Goonetilleke NP,McShane H,Clark SO,Hatch G,Gilbert SC,Hill AV

更新日期：2005-06-01 00:00:00

abstract：:Meningococcal sodC encodes periplasmic copper- and zinc-cofactored superoxide dismutase (Cu,Zn SOD) which catalyzes the conversion of the superoxide radical anion to hydrogen peroxide, preventing a sequence of reactions leading to production of toxic hydroxyl free radicals. From its periplasmic location, Cu,Zn SOD was...

journal_title：Infection and immunity

authors： Wilks KE,Dunn KL,Farrant JL,Reddin KM,Gorringe AR,Langford PR,Kroll JS

更新日期：1998-01-01 00:00:00

abstract：:Tubercle bacilli failed to grow in iron-void media enriched with solutions of iron-containing transferrin (Tr) or ferritin (F) because these substances do not provide the bacilli with iron, which is essential for their growth. Animal serum and macrophages possessed no iron carrier with an ability to satisfy the need o...

journal_title：Infection and immunity

authors： Golden CA,Kochan I,Spriggs DR

更新日期：1974-01-01 00:00:00

abstract：:Helicobacter pylori colonizes the gastric epithelium of at least 50% of the world's human population, playing a causative role in the development of chronic gastritis, peptic ulcers, and gastric adenocarcinoma. Current evidence indicates that H. pylori can invade epithelial cells in the gastric mucosa. However, relati...

journal_title：Infection and immunity

authors： Terebiznik MR,Vazquez CL,Torbicki K,Banks D,Wang T,Hong W,Blanke SR,Colombo MI,Jones NL

更新日期：2006-12-01 00:00:00

abstract：:Representative isolates of nonmucoid Pseudomonas aeruginosa were studied to investigate the hypothesis that mucinophilic and chemotactic properties in this species act as potential factors in the initial stages of pulmonary colonization in patients with cystic fibrosis (CF). Transmission electron microscopy with a sur...

journal_title：Infection and immunity

authors： Nelson JW,Tredgett MW,Sheehan JK,Thornton DJ,Notman D,Govan JR

更新日期：1990-06-01 00:00:00

abstract：:An effective vaccine for Vibrio cholerae is not yet available for use in the developing world, where the burden of cholera disease is highest. Characterizing the proteins that are expressed by V. cholerae in the human host environment may provide insight into the pathogenesis of cholera and assist with the development...

journal_title：Infection and immunity

authors： LaRocque RC,Krastins B,Harris JB,Lebrun LM,Parker KC,Chase M,Ryan ET,Qadri F,Sarracino D,Calderwood SB

更新日期：2008-09-01 00:00:00

abstract：:Schistosoma mansoni-infected wild-type (WT) mice develop a Th2 response and chronic disease. In contrast, infected interleukin-4 double-deficient (IL-4(-/-)) mice develop a Th1-like response and an acute, lethal syndrome. Disease severity in these animals correlates with excessive and prolonged production of nitric ox...

journal_title：Infection and immunity

authors： Patton EA,La Flamme AC,Pedras-Vasoncelos JA,Pearce EJ

更新日期：2002-01-01 00:00:00

abstract：:Various features of salmonellosis were examined in a burned-mouse model. In this model, which uses an outbred mouse strain, a challenge dose of ca. 100 CFU with any of several strains of Salmonella typhimurium caused a fatal infection. A variety of mutated strains attenuated for virulence in Salmonella-susceptible par...

journal_title：Infection and immunity

authors： Carsiotis M,Stocker BA,Holder IA

更新日期：1989-09-01 00:00:00

abstract：:The effects of infection with Rowson-Parr virus (RPV), an associated virus present in Friend virus (FV) preparations, on the splenic plaque-forming cell response to sheep red cells in adult mice and on the plaque-forming cell response of peritoneal cells in vitro have been investigated. The results support the hypothe...

journal_title：Infection and immunity

authors： Bendinelli M,Nardini L

更新日期：1973-02-01 00:00:00

abstract：:Most Campylobacter jejuni strains are sensitive and most Campylobacter fetus strains are resistant to the bactericidal activity in normal human serum. We purified lipopolysaccharides from Campylobacter strains to determine whether their composition and structure relate to serum susceptibility. The lipopolysaccharide o...

journal_title：Infection and immunity

authors： Perez Perez GI,Blaser MJ

更新日期：1985-02-01 00:00:00

abstract：:Despite effective antimicrobial chemotherapy, control of Chlamydia trachomatis urogenital infection will likely require a vaccine. We have assessed the protective effect of an outer membrane protein-based vaccine by using a murine model of chlamydial genital infection. Female mice were first vaccinated with Chlamydia ...

journal_title：Infection and immunity

authors： Farris CM,Morrison SG,Morrison RP

更新日期：2010-10-01 00:00:00

abstract：:Bacterial infection with group B Streptococcus (GBS) represents a prominent threat to neonates and fetuses in the Western world, causing severe organ damage and even death. To improve current therapeutic strategies and to investigate new approaches, an appropriate in vivo model to study the immune response of a human ...

journal_title：Infection and immunity

authors： Ernst W,Zimara N,Hanses F,Männel DN,Seelbach-Göbel B,Wege AK

更新日期：2013-05-01 00:00:00

abstract：:We have investigated the role of lipoteichoic acid in mediating the adherence of different serotypes of group B streptococci to human adult and neonatal epithelial cells. Pretreatment of neonatal buccal and vaginal epithelial cells with lipoteichoic acid, but not with deacylated lipoteichoic acid, induced a marked inh...

journal_title：Infection and immunity

authors： Teti G,Tomasello F,Chiofalo MS,Orefici G,Mastroeni P

更新日期：1987-12-01 00:00:00

abstract：:A strain of a nutritionally deficient streptococcus was shown to undergo morphological aberrations according to pyridoxal concentrations in the growth medium. Filamentous rod-shaped cells, observed by electron microscopy, predominated in the presence of decreasing concentrations. Multiple invaginations in the outer ce...

journal_title：Infection and immunity

authors： Clark RB,Gordon RE,Bottone EJ,Reitano M

更新日期：1983-10-01 00:00:00

abstract：:Salmonella choleraesuis chi 3781, an attenuated [delta cya-12 delta(crp-cdt)19] mutant, was electroporated with the plasmid pBA31-R7, which codes for the expression of a 31-kDa protein from Brucella abortus (BCSP31). Recombinant S. choleraesuis chi 3781 stably maintained the pBA31-R7 plasmid and continued to express t...

journal_title：Infection and immunity

authors： Stabel TJ,Mayfield JE,Morfitt DC,Wannemuehler MJ

更新日期：1993-02-01 00:00:00

abstract：:The intestinal mucosa forms the first line of defense against infections mediated by enteric pathogens such as salmonellae. Here we exploited intestinal "organoids" (iHOs) generated from human induced pluripotent stem cells (hIPSCs) to explore the interaction of Salmonella enterica serovar Typhimurium with iHOs. Imagi...

journal_title：Infection and immunity

authors： Forbester JL,Goulding D,Vallier L,Hannan N,Hale C,Pickard D,Mukhopadhyay S,Dougan G

更新日期：2015-07-01 00:00:00

abstract：:A monoclonal antibody was used to characterize a 135-kDa surface-located membrane protein (Lmp1) generally present in Mycoplasma hominis strains. The monoclonal antibody, 552, was applied to identify the corresponding gene in an expression library of M. hominis PG21 DNA. The M. hominis PG21 lmp1 gene was sequenced, an...

journal_title：Infection and immunity

authors： Ladefoged SA,Birkelund S,Hauge S,Brock B,Jensen LT,Christiansen G

更新日期：1995-01-01 00:00:00

abstract：:The adipocytokine leptin links nutritional status to immune function. Leptin signaling protects from amebiasis, but the molecular mechanism is not understood. We developed an in vitro model of ameba-host cell interaction to test the hypothesis that leptin prevents ameba-induced apoptosis in host epithelial cells. We d...

journal_title：Infection and immunity

authors： Marie CS,Verkerke HP,Paul SN,Mackey AJ,Petri WA Jr

更新日期：2012-05-01 00:00:00

abstract：:A radioimmunoprecipitation method has been devised which permits the direct identification of those proteins which are both exposed on the cell surface of Haemophilus influenzae type b and accessible to antibody. Both extrinsically and intrinsically radiolabeled cells of this organism were employed as the sources of a...

journal_title：Infection and immunity

authors： Hansen EJ,Frisch CF,Johnston KH

更新日期：1981-09-01 00:00:00

abstract：:Porphyromonas gingivalis, a bacterium associated with active chronic periodontitis lesions, produces several proteolytic enzymes that are thought to be involved in host colonization, perturbation of the immune system, and tissue destruction. The aim of the present study was to investigate the contribution of Arg- and ...

journal_title：Infection and immunity

authors： Grenier D,Imbeault S,Plamondon P,Grenier G,Nakayama K,Mayrand D

更新日期：2001-08-01 00:00:00

abstract：:CC chemokine receptor 4 (CCR4) and its two ligands, CCL17 and CCL22, are critically involved in different immune processes. In models of lipopolysaccharide-induced shock, CCR4-deficient (CCR4(-/-)) mice showed improved survival rates associated with attenuated proinflammatory cytokine release. Using CCR4(-/-) mice wit...

journal_title：Infection and immunity

authors： Traeger T,Kessler W,Assfalg V,Cziupka K,Koerner P,Dassow C,Breitbach K,Mikulcak M,Steinmetz I,Pfeffer K,Heidecke CD,Maier S

更新日期：2008-11-01 00:00:00

abstract：:The generation of nitric oxide (NO) by activated macrophages is believed to control mycobacterial infection in the murine system. In this study we examined the effect of Mycobacterium bovis BCG infection on the L-arginine-dependent NO pathway in J774.1 murine macrophages. We have confirmed previous results by demonstr...

journal_title：Infection and immunity

authors： Peteroy-Kelly M,Venketaraman V,Connell ND

更新日期：2001-09-01 00:00:00

abstract：:Avian pathogenic Escherichia coli (APEC) cause extraintestinal disease in avian species via respiratory tract infection. Virulence factors associated with APEC include type 1 and P fimbriae, curli, aerobactin, lipopolysaccharide (LPS), K1 capsular antigen, temperature-sensitive hemagglutinin (Tsh), and an uncharacteri...

journal_title：Infection and immunity

authors： Mellata M,Dho-Moulin M,Dozois CM,Curtiss R 3rd,Lehoux B,Fairbrother JM

更新日期：2003-01-01 00:00:00

abstract：:Four monoclonal antibodies (MAbs) were produced by immunizing mice with a disrupted yeast cell homogenate of Histoplasma capsulatum. MAbs 1 and 2 reacted only with the yeast cell antigens of H. capsulatum and Blastomyces dermatitidis, whereas MAbs 3 and 4 showed broader cross-reactivity. MAb 3 cross-reacted with B. de...

journal_title：Infection and immunity

authors： Kamel SM,Wheat LJ,Garten ML,Bartlett MS,Tansey MR,Tewari RP

更新日期：1989-03-01 00:00:00

abstract：:Mycobacterium tuberculosis, the primary etiologic agent of tuberculosis, is the world's leading cause of death from a single infectious agent, and new vaccines and drugs to combat it are urgently needed. The major extracellular proteins of M. tuberculosis, which are released into its phagosome in macrophages, its host...

journal_title：Infection and immunity

authors： Harth G,Lee BY,Horwitz MA

更新日期：1997-06-01 00:00:00

abstract：:The selection of influenza B virus recombinants from plaques in bovine kidney cell monolayers is described. Two sets of recombinants were each derived from parents of high and low virulence for humans, respectively. Recombination frequency was apparently high, and reassortment of genes made it possible to obtain atten...

journal_title：Infection and immunity

authors： Beare AS,Sherwood JE,Callow KA,Craig JW

更新日期：1977-02-01 00:00:00

abstract：:In the lungs of mice vaccinated with Mycobacterium bovis BCG, there was an accumulation of CD4 cells expressing the activated effector phenotype CD44hi CD62 ligandlo) (CD62Llo) which were capable of secreting gamma interferon. Upon cell transfer, however, cells expressing a resting/naïve phenotype (CD44lo CD62Lhi) wer...

journal_title：Infection and immunity

authors： Kipnis A,Irwin S,Izzo AA,Basaraba RJ,Orme IM

更新日期：2005-11-01 00:00:00

abstract：:Inbred BALB/c mice were either immunized with Triton X-100-extracted antigens of blood-stage Plasmodium yoelii or infected with P. yoelii and cured in three successive schedules. Whereas the immunized BALB/c became only partially protected from subsequent challenge infection with blood-stage P. yoelii, the convalescen...

journal_title：Infection and immunity

authors： Kironde FA,Kumar A,Nayak AR,Kraikov JL

更新日期：1991-11-01 00:00:00