Abstract:
:The effects of infection with Rowson-Parr virus (RPV), an associated virus present in Friend virus (FV) preparations, on the splenic plaque-forming cell response to sheep red cells in adult mice and on the plaque-forming cell response of peritoneal cells in vitro have been investigated. The results support the hypothesis that RPV might be responsible for a considerable proportion of the early immunodepressive effects caused by FV preparations.
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Bendinelli M,Nardini Ldoi
10.1128/IAI.7.2.160-166.1973subject
Has Abstractpub_date
1973-02-01 00:00:00pages
160-6issue
2eissn
0019-9567issn
1098-5522journal_volume
7pub_type
杂志文章abstract::Nerve damage is a clinical hallmark of leprosy and a major source of patient morbidity. We investigated the possibility that human Schwann cells are susceptible to cell death through the activation of Toll-like receptor 2 (TLR2), a pattern recognition receptor of the innate immune system. TLR2 was detected on the surf...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.71.3.1427-1433.2003
更新日期:2003-03-01 00:00:00
abstract::A model of invasive Haemophilus influenzae type b disease in rats was used to compare the net in vivo and in vitro multiplication rates of this bacterium. In both the blood of rats and in vitro cultures (fresh rat blood or enriched broth) there was an exponential increase in the number of CFU per milliliter with calcu...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.52.3.911-913.1986
更新日期:1986-06-01 00:00:00
abstract::Several immunological, hematological, and pathological responses associated with Marek's disease were determined. Four-week-old Marek's disease-infected and control chickens were injected with Salmonella pullorum antigen. About one-half of all infected chickens tested were unresponsive to antigenic challenge. Antibody...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.4.5.567-574.1971
更新日期:1971-11-01 00:00:00
abstract::The bactericidal and opsonizing effects of normal human serum on six strains of Salmonella typhimurium LT-2 having different lipopolysaccharide (LPS) composition were demonstrated through five indices. Complement activity in the presence of antibody was important for the opsonization of all six strains and for the bac...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.49.3.647-653.1985
更新日期:1985-09-01 00:00:00
abstract::Recent epidemiological observations suggest that clinical evolution of Plasmodium falciparum infections might be influenced by the concurrent presence of another Plasmodium species, and such mixed-species infections are now known to occur frequently in residents of most areas of endemicity. We used mice infected with ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.73.8.4777-4786.2005
更新日期:2005-08-01 00:00:00
abstract::Pseudomonas aeruginosa invades various epithelial cell types in vitro and in vivo. The P. aeruginosa genome possesses a gene (flhA) which encodes a protein that is believed to be part of the export apparatus for flagellum assembly and which is homologous to invA of Salmonella spp. Because invA is required for invasion...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.69.8.4931-4937.2001
更新日期:2001-08-01 00:00:00
abstract::In this study we have characterized the association of a polysaccharide-deficient, lipid-rich lipopolysaccharide (LPS) with rabbit erythrocytes (RaRBC). With polymyxin B sulfate-mediated hemolysis as a probe, we have shown that Salmonella minnesota R595 LPS interacts with RaRBC in two distinguishable steps. The first ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.43.2.600-606.1984
更新日期:1984-02-01 00:00:00
abstract::Phagosome acidification is an important component of the microbicidal response by infected eukaryotic cells. Thus, intracellular pathogens that reside within phagosomes must either block phagosome acidification or be able to survive at low pH. In this work, we studied the effect of phagosomal acidification on the surv...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.68.9.5401-5404.2000
更新日期:2000-09-01 00:00:00
abstract::The Mycobacterium tuberculosis exported repetitive protein (Erp) is a virulence determinant required for growth in cultured macrophages and in vivo. To better understand the role of Erp in Mycobacterium pathogenesis, we generated a mutation in the erp homologue of Mycobacterium marinum, a close genetic relative of M. ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.02061-05
更新日期:2006-06-01 00:00:00
abstract::Pathogenic leptospires have the ability to survive and disseminate to multiple organs after penetrating the host. Several pathogens, including spirochetes, have been shown to express surface proteins that interact with the extracellular matrix (ECM). This adhesin-mediated binding process seems to be a crucial step in ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00460-06
更新日期:2006-11-01 00:00:00
abstract::Individuals living in areas where malaria is endemic are repeatedly exposed to many different malaria parasite antigens. Studies on naturally acquired antibody-mediated immunity to clinical malaria have largely focused on the presence of responses to individual antigens and their associations with decreased morbidity....
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01585-07
更新日期:2008-05-01 00:00:00
abstract::The involvement of tumor necrosis factor (TNF) in resistance to Toxoplasma gondii infection was examined by means of experiments in which mice were treated with anti-TNF antibodies prior to infection with ME49, a low-virulence Toxoplasma strain. In (BALB/cBy x C57BL/6J)F1 (CB6F1) mice, which are highly resistant to in...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.60.5.1979-1983.1992
更新日期:1992-05-01 00:00:00
abstract::The virulence of Neisseria gonorrhoeae for chicken embryos can be modified in a predictable manner by the addition of microbial siderophores to the inoculum. "Meningobactin" and "gonobactin," siderophores isolated from iron-limited cultures of meningococci and gonococci, respectively, enhance the virulence of the rela...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.32.2.609-613.1981
更新日期:1981-05-01 00:00:00
abstract::Mycoplasma arthritidis causes acute polyarthritis in rats and chronic proliferative arthritis in mice. M. arthritidis-induced arthritis serves as a model for arthritis caused by infectious agents and as a model for examining the role of the superantigen MAM (M. arthritidis T-cell mitogen) in the development of autoimm...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.73.1.245-249.2005
更新日期:2005-01-01 00:00:00
abstract::The recent finding that high numbers of strict anaerobes are present in the respiratory tract of cystic fibrosis (CF) patients has drawn attention to the pathogenic contribution of the CF microbiome to airway disease. In this study, we investigated the specific interactions of the most dominant bacterial CF pathogen, ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.02234-14
更新日期:2015-01-01 00:00:00
abstract::Mucosal immune responses to fungal infection range from T helper type 2 (Th2) cell-directed allergic inflammation to Th1-predominant neutrophilic inflammation, but the mechanisms directing these divergent mucosal immune outcomes and the role of T cells in host defense against mucosal fungal infections are not known. H...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.05209-11
更新日期:2011-11-01 00:00:00
abstract::The levels of protection found in vaccine studies of murine visceral leishmaniasis are significantly lower than for cutaneous leishmaniasis; whether this is due to the high-challenge murine model employed and/or is a consequence of differences required in tissue-specific local immune responses is not understood. Conse...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.71.1.401-410.2003
更新日期:2003-01-01 00:00:00
abstract::Existing evidence suggests that oxidative insults and antioxidant defense mechanisms play a critical role in the host cell response during infection of endothelial cells by Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever. Heme oxygenase (HO), a rate-limiting enzyme in the pathway for heme ca...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.70.8.4045-4052.2002
更新日期:2002-08-01 00:00:00
abstract::One mechanism by which interferons (IFNs) can inhibit chlamydial infection is by the induction of the enzyme indoleamine 2,3-dioxygenase (IDO), which restricts the availability of tryptophan, which is required for chlamydial growth. Other immunomodulating agents, including interleukin-1 (IL-1), can interact synergisti...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.63.5.1870-1875.1995
更新日期:1995-05-01 00:00:00
abstract::Inactivated Marek's disease virus-infected chicken kidney cells and inactivated MSB-1 lymphoblastoid Marek's disease tumor cells were used to immunize chickens as virus- and tumor-associated antigens, respectively. Immune and nonimmune birds were then challenged by exposure to live virulent Marek's disease virus. Both...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.26.2.547-553.1979
更新日期:1979-11-01 00:00:00
abstract::Porphyromonas gingivalis, a periodontopathic bacterium, is known to invade oral epithelial cells in periodontal lesions, although the mechanism is unclear. In the present study, goat polyclonal anti-intercellular adhesion molecule 1 (anti-ICAM-1) antibody inhibited the invasion of P. gingivalis into KB cells (human or...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.73.10.6290-6298.2005
更新日期:2005-10-01 00:00:00
abstract::We have previously described (L. M. Vaughan, P. R. Smith, and T. J. Foster, Infect. Immun. 61:2172-2181, 1993) the construction of a kanamycin-resistant aromatic-dependent mutant of Aeromonas salmonicida, the causative agent of furunculosis, and its use as a live vaccine. Here we describe the construction of an unmark...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.64.9.3863-3869.1996
更新日期:1996-09-01 00:00:00
abstract::We have shown previously that Klebsiella pneumoniae receptors for coliphages T3 and T7 also mediate mannose-inhibitable adherence to human epithelial cells and protect bacteria from phagocytosis and intracellular killing by human polymorphonuclear cells. In this paper we analyze the possible role of such mannose-inhib...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.39.2.520-527.1983
更新日期:1983-02-01 00:00:00
abstract::We investigated the effects of peripheral blood mononuclear cells expanded with irrelevant control and mycobacterial antigens on the intracellular growth of Mycobacterium bovis bacillus Calmette-Guérin (BCG) in human macrophages. More than 90% of the cells present after 1 week of in vitro expansion were CD3(+). T cell...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.71.4.1763-1773.2003
更新日期:2003-04-01 00:00:00
abstract::Agglutinogen 1 of Bordetella pertussis strain 353/Z (serotype 1) was separated from protective antigen and histamine-sensitizing factor by starch-block electrophoresis. Most of the agglutinogen 1 migrated towards the cathode in starch-block electrophoresis, although some remained near the origin. Fractions containing ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.3.2.243-248.1971
更新日期:1971-02-01 00:00:00
abstract::A simple and convenient method was developed for the preparation of Streptococcus pneumoniae type 14 polysaccharide (Pn14PS)-tetanus toxoid (TT) conjugate vaccines, using terminally linked Pn14PS fragments of different lengths. Native Pn14PS was simultaneously depolymerized and activated for conjugation by partial N-d...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.66.6.2441-2446.1998
更新日期:1998-06-01 00:00:00
abstract::Continuous virus production is a characteristic of chicken embryo fibroblasts (CEF) infected and transformed by a nondefective Schmidt-Ruppin subgroup A Rous sarcoma virus. This virus production has been examined with particular attention to the amount of newly budded virus which remained cell-associated, and to the a...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.10.4.834-843.1974
更新日期:1974-10-01 00:00:00
abstract::An enterotoxin produced by Bacteroides fragilis was purified to homogeneity and characterized as to its biological activity and basic molecular properties. Toxin preparations were prepared by growing B. fragilis VPI 13784 in brain heart infusion broth to early stationary phase, immediately precipitating the culture su...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.60.4.1343-1350.1992
更新日期:1992-04-01 00:00:00
abstract::Heat-labile enterotoxins from Escherichia coli strains of porcine and human origin polymerize on heating to form high-molecular-weight aggregates, "procoligenoids," analogous to procholeragenoid derived from the cholera enterotoxin. This aggregation is accompanied by loss of biological activity (toxicity). Further hea...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.45.2.518-521.1984
更新日期:1984-08-01 00:00:00
abstract::A recombinant plasmid designated pAW305, containing a 6-kilobase insert of Treponema pallidum DNA, directed the expression of a 38-kilodalton (kDa) treponemal antigen in Escherichia coli. The 38-kDa antigen copurified with the outer membrane fraction of the E. coli cell envelope after treatment with nonionic detergent...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.52.2.586-593.1986
更新日期:1986-05-01 00:00:00