Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells.

abstract：:The adherence of Treponema denticola GM-1, TD-4, and MS25 to human gingival fibroblasts (HGFs) was studied to serve as an introduction to investigations into the interactions of these oral bacteria with human host cells. Under both aerobic (5% CO2) and anaerobic (85% N2 plus 10% H2 plus 5% CO2) environments, the inter...

journal_title：Infection and immunity

authors： Weinberg A,Holt SC

更新日期：1990-06-01 00:00:00

abstract：:Pseudomonas aeruginosa elastase rapidly inactivates alpha 1-proteinase inhibitor by splitting its Pro-357-Met-358 peptide bond. The present study was aimed at testing whether this reaction takes place in the presence of leukocyte elastase. To this end was added alpha 1-proteinase inhibitor to a mixture of the two elas...

journal_title：Infection and immunity

authors： Padrines M,Bieth JG

更新日期：1989-12-01 00:00:00

abstract：:Whooping cough results from infection of the respiratory tract with Bordetella pertussis, and the secreted adenylate cyclase toxin (ACT) is essential for the bacterium to establish infection. Despite extensive study of the mechanism of ACT cytotoxicity and its effects over a range of concentrations in vitro, ACT has n...

journal_title：Infection and immunity

authors： Eby JC,Gray MC,Warfel JM,Paddock CD,Jones TF,Day SR,Bowden J,Poulter MD,Donato GM,Merkel TJ,Hewlett EL

更新日期：2013-05-01 00:00:00

abstract：:Bordetella bronchiseptica is closely related to Bordetella pertussis, which produces respiratory disease primarily in mammals other than humans. However, its importance as a human pathogen is being increasingly recognized. Although a large amount of research on Bordetella has been generated regarding protein virulence...

journal_title：Infection and immunity

authors： Sisti F,Fernández J,Rodríguez ME,Lagares A,Guiso N,Hozbor DF

更新日期：2002-04-01 00:00:00

abstract：:In a mouse model of thermal injury, an increase in burn size produced a decrease in the ratio of Candida albicans cells adherent to the marginal zone to those adherent to the white pulp of the spleen, an increase in the number of Candida cells in the circulation and in the kidneys, and an increase in mortality. ...

journal_title：Infection and immunity

authors： Neely AN,Orloff MM,Holder IA,Healy DP

更新日期：1997-08-01 00:00:00

abstract：:The initial encounter of Leishmania cells and cells from the immune system is fundamentally important in the outcome of infection and determines disease development or resistance. We evaluated the anti-Leishmania amazonensis response of naive volunteers by using an in vitro priming (IVP) system and comparing the respo...

journal_title：Infection and immunity

authors： Pompeu MM,Brodskyn C,Teixeira MJ,Clarêncio J,Van Weyenberg J,Coelho IC,Cardoso SA,Barral A,Barral-Netto M

更新日期：2001-12-01 00:00:00

abstract：:At pH 7.4 and in the presence of NaHCO3, human milk and bovine colostrum inhibited the growth of Escherichia coli O111. Adding sufficient iron to saturate the iron-binding capacity of the lactoferrin present in the milk or colostrum prevented bacteriostasis. At pH 6.8 neither molk nor colostrum inhibited E. coli 0111....

journal_title：Infection and immunity

authors： Griffiths E,Humphreys J

更新日期：1977-02-01 00:00:00

abstract：:Nonvertebrate model hosts represent valuable tools for the study of host-pathogen interactions because they facilitate the identification of bacterial virulence factors and allow the discovery of novel components involved in host innate immune responses. In this report, we determined that the greater wax moth caterpil...

journal_title：Infection and immunity

authors： Miyata S,Casey M,Frank DW,Ausubel FM,Drenkard E

更新日期：2003-05-01 00:00:00

abstract：:Naturally occurring antibodies for Vibrio fetus with whole-cell and O antigen specificities were detected in sera of mature cattle by means of the agglutination and indirect immunofluorescence reactions. O antibodies occurred in each of 21 sera examined, and whole-cell antibodies, in lower concentrations, occurred in ...

journal_title：Infection and immunity

authors： Duncan JR,Wilkie BN,Winter AJ

更新日期：1972-05-01 00:00:00

abstract：:OKM5 antigen and thrombospondin are currently under investigation as potential receptors on the surface of human monocytes, endothelial cells, and melanomas responsible for the cytoadherence of Plasmodium falciparum-infected erythrocytes. We have studies the binding capacity of six human melanoma cell lines and relate...

journal_title：Infection and immunity

authors： Panton LJ,Leech JH,Miller LH,Howard RJ

更新日期：1987-11-01 00:00:00

abstract：:A recombinant plasmid designated pAW305, containing a 6-kilobase insert of Treponema pallidum DNA, directed the expression of a 38-kilodalton (kDa) treponemal antigen in Escherichia coli. The 38-kDa antigen copurified with the outer membrane fraction of the E. coli cell envelope after treatment with nonionic detergent...

journal_title：Infection and immunity

authors： Fehniger TE,Radolf JD,Walfield AM,Cunningham TM,Miller JN,Lovett MA

更新日期：1986-05-01 00:00:00

abstract：:Meningococcal sodC encodes periplasmic copper- and zinc-cofactored superoxide dismutase (Cu,Zn SOD) which catalyzes the conversion of the superoxide radical anion to hydrogen peroxide, preventing a sequence of reactions leading to production of toxic hydroxyl free radicals. From its periplasmic location, Cu,Zn SOD was...

journal_title：Infection and immunity

authors： Wilks KE,Dunn KL,Farrant JL,Reddin KM,Gorringe AR,Langford PR,Kroll JS

更新日期：1998-01-01 00:00:00

abstract：:Help from CD4 T cells is often important for the establishment of primary and memory CD8 T-cell responses. However, it has yet to be determined whether T helper polarization affects the delivery of help and/or whether responding CD8 T cells helped by Th1 or Th2 cells express distinct effector properties. To address th...

journal_title：Infection and immunity

authors： Ekkens MJ,Shedlock DJ,Jung E,Troy A,Pearce EL,Shen H,Pearce EJ

更新日期：2007-05-01 00:00:00

abstract：:Anaplasma marginale subsp. centrale was the first vaccine used to protect against a rickettsial disease and is still in widespread use a century later. As its use preceded development of either cryopreservation or cell culture, the vaccine strain was maintained for decades by sequential passage among donor animals, ex...

journal_title：Infection and immunity

authors： Herndon DR,Ueti MW,Reif KE,Noh SM,Brayton KA,Agnes JT,Palmer GH

更新日期：2013-05-01 00:00:00

abstract：:Oophorectomized, estrogen-treated rats were immunized by the intravaginal or intranasal route with a mannoprotein extract (MP) or secreted aspartyl proteinases (Sap) of Candida albicans, with or without cholera toxin as a mucosal adjuvant. Both routes of immunization were equally effective in (i) inducing anti-MP and ...

journal_title：Infection and immunity

authors： De Bernardis F,Boccanera M,Adriani D,Girolamo A,Cassone A

更新日期：2002-05-01 00:00:00

abstract：:Saccharomyces boulardii, a nonpathogenic yeast, is effective in treating some patients with Clostridium difficile diarrhea and colitis. We have previously reported that S. boulardii inhibits rat ileal secretion in response to C. difficile toxin A possibly by releasing a protease that digests the intestinal receptor fo...

journal_title：Infection and immunity

authors： Castagliuolo I,LaMont JT,Nikulasson ST,Pothoulakis C

更新日期：1996-12-01 00:00:00

abstract：:Serotypes A and B of the relapsing fever spirochete Borrelia turicatae produce different disease manifestations in infected mice. Whereas serotype B causes more severe arthritis and reaches higher densities in the blood of mice than serotype A, serotype A invades the central nervous system earlier than serotype B duri...

journal_title：Infection and immunity

authors： Pennington PM,Cadavid D,Barbour AG

更新日期：1999-09-01 00:00:00

abstract：:Bordetella pertussis was grown in iron (Fe)-free defined medium to limit the growth of the organism. Doubling times of the Fe-starved organism increased by approximately 1 h, and a 40% reduction in the final extent of growth in Fe-depleted medium was observed. Under these conditions, a hydroxamate siderophore named bo...

journal_title：Infection and immunity

authors： Agiato LA,Dyer DW

更新日期：1992-01-01 00:00:00

abstract：:Interstitial lung macrophages from tuberculosis-susceptible I/St and tuberculosis-resistant A/Sn mice demonstrated significant constitutive differences in gene expression levels, whereas in vitro infection of these cells with Mycobacterium tuberculosis had only a modulatory impact on gene expression. We conclude that ...

journal_title：Infection and immunity

authors： Orlova MO,Majorov KB,Lyadova IV,Eruslanov EB,M'lan CE,Greenwood CM,Schurr E,Apt AS

更新日期：2006-06-01 00:00:00

abstract：:Synthetic Escherichia coli lipid A and synthetic S-[2,3-bis-(palmitoyloxy)propyl]-N-palmitoylpentapeptide (tripalmitoyl pentapeptide [TPP]), representing the mitogenically active principles of bacterial lipopolysaccharide (LPS) and lipoprotein, respectively, were compared for their mitogenic activities on splenocytes ...

journal_title：Infection and immunity

authors： Brade L,Bessler WG,Brade H

更新日期：1988-05-01 00:00:00

abstract：:A nonproteolytic strain of Clostridium botulinum type B produces two toxins of different molecular weight (16S and 12S) that are indistinguishable from the corresponding toxins of a proteolytic strain in molecular weight and construction but differ in potential toxicity, activation ratio, and hemagglutinability. Succe...

journal_title：Infection and immunity

authors： Miyazaki S,Kozaki S,Sakaguchi S,Sakaguchi G

更新日期：1976-03-01 00:00:00

abstract：:Lipopolysaccharide (LPS) can induce mouse macrophages to produce a number of cytokines and other inflammatory mediators. Our laboratory previously reported that LPS-dependent macrophage-derived tumor necrosis factor alpha (TNF-alpha) production could be significantly potentiated by pretreatment with LPS at substimulat...

journal_title：Infection and immunity

authors： Hirohashi N,Morrison DC

更新日期：1996-03-01 00:00:00

abstract：:The leading malaria vaccine candidate, RTS,S, based on the Plasmodium falciparum circumsporozoite protein (CSP), will likely be the first publicly adopted malaria vaccine. However, this and other subunit vaccines, such as virus-vectored thrombospondin-related adhesive protein (TRAP), provide only intermediate to low l...

journal_title：Infection and immunity

authors： Bauza K,Atcheson E,Malinauskas T,Blagborough AM,Reyes-Sandoval A

更新日期：2015-12-14 00:00:00

abstract：:Thirty-two clinical isolates of Shiga-like toxin (SLT)-producing Escherichia coli associated with single cases or outbreaks of bloody diarrhea, hemorrhagic colitis, the hemolytic uremic syndrome, or edema disease of swine were examined for multiple copies of genes belonging to the slt-I or slt-II toxin families. Five ...

journal_title：Infection and immunity

authors： Schmitt CK,McKee ML,O'Brien AD

更新日期：1991-03-01 00:00:00

abstract：:Purified cell walls representing a wide variety in teichoic acid and peptidoglycan structure prepared from eight different gram-positive bacterial species induced the production of tumor necrosis factor alpha (TNF-alpha) and interleukin-6 from human monocytes in the presence of 10% plasma or serum. Significant amounts...

journal_title：Infection and immunity

authors： Heumann D,Barras C,Severin A,Glauser MP,Tomasz A

更新日期：1994-07-01 00:00:00

abstract：:Virus population dynamics in the lungs, trachea, and nasopharynx of Swiss-ICR mice were studied after respiratory challenge with mouse-adapted preparations of strain A2/Aichi/2/68 influenza virus. Markedly higher doses of virus were required to produce infection with nasopharyngeal challenge than with bronchoalveolar ...

journal_title：Infection and immunity

authors： Larson EW,Dominik JW,Rowberg AH,Higbee GA

更新日期：1976-02-01 00:00:00

abstract：:The kinetics and homing characteristics of T-cell responses in humans after mucosal immunizations have not been well characterized. Therefore, we have investigated the magnitude and duration of such responses as well as the homing receptor expression of antigen-specific peripheral blood T cells by using an oral model ...

journal_title：Infection and immunity

authors： Lundin BS,Johansson C,Svennerholm AM

更新日期：2002-10-01 00:00:00

abstract：:The Escherichia coli blood culture isolate BK658 (O75:K1:H7) expresses F1A and F1B fimbriae as well as a third fimbrial type which reacts with anti-S-fimbrial antiserum but fails to show S-specific binding properties (i.e., agglutination of bovine erythrocytes). To characterize these fimbriae, we cloned the respective...

journal_title：Infection and immunity

authors： Pawelzik M,Heesemann J,Hacker J,Opferkuch W

更新日期：1988-11-01 00:00:00

abstract：:Borrelia burgdorferi is a causative agent of Lyme disease, the most common arthropod-borne disease in the United States. B. burgdorferi evades host immune defenses to establish a persistent, disseminated infection. Previous work showed that P66-deficient B. burgdorferi (Δp66) is cleared quickly after inoculation in mi...

journal_title：Infection and immunity

authors： Curtis MW,Hahn BL,Zhang K,Li C,Robinson RT,Coburn J

更新日期：2018-01-22 00:00:00

abstract：:A differential-display PCR procedure identified the capsular assembly gene kpsD after Escherichia coli type 1 fimbrial binding to mannose-coated Sepharose beads. Limiting-dilution reverse-transcribed PCRs confirmed down-regulation of the kpsD gene, and Northern blot and lacZ fusion analyses showed down-regulation of t...

journal_title：Infection and immunity

authors： Schwan WR,Beck MT,Hultgren SJ,Pinkner J,Woolever NL,Larson T

更新日期：2005-02-01 00:00:00