Tailoring a Combination Preerythrocytic Malaria Vaccine.

abstract：:We have previously demonstrated that protection from allergic inflammation by Ascaris suum infection was characterized by a global increase in interleukin-10 (IL-10) and the development of protective CD4(+)/CD25(+) T cells (L. Schopf, S. Luccioli, V. Bundoc, P. Justice, C. C. Chan, B. J. Wetzel, H. H. Norris, J. F. Ur...

journal_title：Infection and immunity

authors： McConchie BW,Norris HH,Bundoc VG,Trivedi S,Boesen A,Urban JF Jr,Keane-Myers AM

更新日期：2006-12-01 00:00:00

abstract：:Aeromonas salmonicida causes furunculosis in salmonids and is a threat to Atlantic salmon aquaculture. The epithelial surfaces that the pathogen colonizes are covered by a mucus layer predominantly comprised of secreted mucins. By using mass spectrometry to identify mucin glycan structures with and without enzymatic r...

journal_title：Infection and immunity

authors： Padra JT,Sundh H,Sundell K,Venkatakrishnan V,Jin C,Samuelsson T,Karlsson NG,Lindén SK

更新日期：2017-07-19 00:00:00

abstract：:Localized juvenile periodontosis is associated with a defect of neutrophil chemotaxis that is characterized by selective depletion of a surface protein with a molecular mass of 110 kDa (GP110). Data on partial characterization of GP110 suggest that it is a glycoprotein which is enriched in Lys, Glu, His, Leu, and Ala ...

journal_title：Infection and immunity

authors： Tripathi SC,Van Dyke TE

更新日期：1992-07-01 00:00:00

abstract：:Ten micrograms of trehalose-6,6' -dimycolate (cord factor) injected into the footpads of mice increased the antibody response to sheep red blood cells (SRBC) subsequently injected into the same sites. There is a relationship between the antibody response and the cellular reaction induced locally and in the draining ly...

journal_title：Infection and immunity

authors： Bekierkunst A,Yarkoni E,Flechner I,Morecki S,Vilkas E,Lederer E

更新日期：1971-09-01 00:00:00

abstract：:Nine goats were injected transthoracically with Pasteurella haemolytica A1 to determine if an extracellular bacterial enzyme, neuraminidase, was produced in vivo during infection with this organism. The principal group of goats (n = 9) each received 1 ml of 7.25 x 10(5) live P. haemolytica A1 cells in polyacrylate bea...

journal_title：Infection and immunity

authors： Straus DC,Purdy CW

更新日期：1994-10-01 00:00:00

abstract：:Naturally occurring antibodies against [Gal alpha-1,3-Gal] structures (anti-Gal antibodies) are the primary effectors of human hyperacute rejection (HAR) of nonhuman tissue. Unlike most mammals, humans lack a functional alpha-1,3-galactosyltransferase (GalT) gene and produce abundant anti-Gal antibodies, putatively in...

journal_title：Infection and immunity

authors： Posekany KJ,Pittman HK,Bradfield JF,Haisch CE,Verbanac KM

更新日期：2002-11-01 00:00:00

abstract：:Mice immunized subcutaneously with heat-killed Escherichia coli were protected from pyelonephritis produced by the intravenous route, but there was little or no protection from ascending infection. No significant protection from ascending or hematogenous pyelonephritis was demonstrated when immunization was accomplish...

journal_title：Infection and immunity

authors： Montgomerie JZ,Kalmanson GM,Hubert EG,Guze LB

更新日期：1972-09-01 00:00:00

abstract：:Corynebacterium renale type I (strain 115), 1.7 X 10(7) to 4.5 X 10(7) organisms, introduced intravenously into mice disappeared from the blood less than 24 h after inoculation and did not produce pyelonephritis. The same strain, 1 X 10(7) to 5 X 10(7) organisms, inoculated into the urinary bladder of mice was not rec...

journal_title：Infection and immunity

authors： Shimono E,Yanagawa R

更新日期：1977-04-01 00:00:00

abstract：:An acute and persistent eosinophil infiltration is observed during Mycobacterium bovis BCG pleural infection in mice. Eosinophil accumulation, lipid body formation, and eotaxin production were significantly reduced in BCG-infected Toll-like receptor-2 (TLR2)-deficient mice compared to wild-type mice. Neutralization of...

journal_title：Infection and immunity

authors： D'Avila H,Almeida PE,Roque NR,Castro-Faria-Neto HC,Bozza PT

更新日期：2007-03-01 00:00:00

abstract：:The effect of continuous exposure to 80% oxygen on newborn mice with Ureaplasma urealyticum pneumonia was determined. Mice were inoculated intranasally with either U. urealyticum or sterile broth and then housed in either 80% oxygen or room air (21% oxygen). The mice were sacrificed at either 7 or 14 days after inocul...

journal_title：Infection and immunity

authors： Crouse DT,Cassell GH,Waites KB,Foster JM,Cassady G

更新日期：1990-11-01 00:00:00

abstract：:Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic lung infections in cystic fibrosis patients. Iron is essential for bacterial growth, and P. aeruginosa expresses multiple iron uptake systems, whose role in lung infection deserves further investigation. P. aeruginosa Fe(3+) uptake sy...

journal_title：Infection and immunity

authors： Minandri F,Imperi F,Frangipani E,Bonchi C,Visaggio D,Facchini M,Pasquali P,Bragonzi A,Visca P

更新日期：2016-07-21 00:00:00

abstract：:Mice were protected against a lethal infection with Listeria monocytogenes when treated with low doses of an anti-CD3 monoclonal antibody (MAb). Injection of anti-CD3 MAb induced rapid production of endogenous tumor necrosis factor (TNF) in the spleens and endogenous gamma interferon (IFN-gamma) in the bloodstreams an...

journal_title：Infection and immunity

authors： Nakane A,Okamoto M,Asano M,Kohanawa M,Minagawa T

更新日期：1993-07-01 00:00:00

abstract：:The mechanism of adsorption of the Streptococcus mutans enzymes responsible for the synthesis of insoluble dextran-levan to the S. mutans cell-wall binding sites has been studied. Certain characteristics of these binding sites are presented. The adsorption of these enzymes to the cell surface occurred rapidly without ...

journal_title：Infection and immunity

authors： Mukasa H,Slade HD

更新日期：1974-02-01 00:00:00

abstract：:l-Arginine (1 M) eluted measles virus adsorbed on monkey erythrocytes without affecting the infectious and hemagglutinating activities of the virus. This phenomenon was also observed for encephalomyocarditis virus and Newcastle disease virus. ...

journal_title：Infection and immunity

authors： Lebon P,Protat A,Moline P

更新日期：1975-06-01 00:00:00

abstract：:Human colostrum, parotid saliva, and serum were assayed for the presence of naturally occurring antibodies to five serotypes of Streptococcus mutans. Appreciable levels of agglutinins to strains AHT, BHT, 10449, 6715, and LM-7 (groups a leads to e, respectively) were detected in normal colostrum and saliva, whereas re...

journal_title：Infection and immunity

authors： Arnold RR,Mestecky J,McGhee JR

更新日期：1976-08-01 00:00:00

abstract：:Escherichia coli O45 isolates associated with swine postweaning diarrhea in Québec were characterized with respect to virulence determinants genetically and investigated for their attaching and effacing (A/E) activities by experimental inoculation of gnotobiotic piglets and by the HEp-2 cell adherence assay. All of 32...

journal_title：Infection and immunity

authors： Zhu C,Harel J,Jacques M,Desautels C,Donnenberg MS,Beaudry M,Fairbrother JM

更新日期：1994-10-01 00:00:00

abstract：:The formation of water-insoluble glucan by extracellular glucosyltransferase from Streptococcus mutans 6715 found to be greatly stimulated by various mono- or divalent cations. An enzyme preparation, obtained by ethanol fractionation, was able to catalyze the formation of water-insoluble glucan from sucrose in the pre...

journal_title：Infection and immunity

authors： Mukasa H,Shimamura A,Tsumori H

更新日期：1979-03-01 00:00:00

abstract：:Streptococcus pneumoniae infection leads to multifold increases in sialyltransferase, galactosyltransferase, alpha 2-fucosyltransferase, and alpha 3-fucosyltransferase activity of rat liver. Such changes may reflect an increased demand for glycosylation of acute-phase proteins synthesized and secreted by the liver dur...

journal_title：Infection and immunity

authors： Canonico PG,Little JS,Powanda MC,Bostian KA,Beisel WR

更新日期：1980-07-01 00:00:00

abstract：:The response of the intracellular pathogen Rhodococcus equi to H(2)O(2) treatment, a situation potentially encountered after the oxidative burst of alveolar macrophages, was analyzed. Compared to other bacteria, including Deinococcus radiodurans, R. equi showed exceptionally high resistance to this stress. A proteomic...

journal_title：Infection and immunity

authors： Benoit S,Benachour A,Taouji S,Auffray Y,Hartke A

更新日期：2002-07-01 00:00:00

abstract：:Rabbit endogenous pyrogens occurred in two forms. One was an apparently single protein with a pI of 7.3; the other was a family of proteins with pI values of 4.5 to 5.0. We selected two of the latter, with pI values of 4.6 and 4.72, as representative of the group and compared them with the pI 7.3 pyrogen. Antisera rai...

journal_title：Infection and immunity

authors： Murphy PA,Cebula TA,Levin J,Windle BE

更新日期：1981-10-01 00:00:00

abstract：:Ehrlichia chaffeensis is an obligately intracellular gram-negative bacterium and is the etiologic agent of human monocytic ehrlichiosis (HME). Although E. chaffeensis induces the generation of several cytokines and chemokines by leukocytes, E. chaffeensis lacks lipopolysaccharide and peptidoglycan. Bioinfomatic analys...

journal_title：Infection and immunity

authors： Huang H,Lin M,Wang X,Kikuchi T,Mottaz H,Norbeck A,Rikihisa Y

更新日期：2008-08-01 00:00:00

abstract：:IL12RB1 is a human gene that is important for resistance to Mycobacterium tuberculosis infection. IL12RB1 is expressed by multiple leukocyte lineages, and encodes a type I transmembrane protein (IL12Rβ1) that associates with IL12p40 and promotes the development of host-protective T(H)1 cells. Recently, we observed tha...

journal_title：Infection and immunity

authors： Ray AA,Fountain JJ,Miller HE,Cooper AM,Robinson RT

更新日期：2015-02-01 00:00:00

abstract：:A live, attenuated, recombinant influenza vaccine (Alice strain) administered intranasally was evaluated in high school students and compared with intranasal placebo and subcutaneous, inactivated, bivalent influenza vaccine. The Alice strain was antigenic, increasing the geometric mean titer (GMT) from a prestudy leve...

journal_title：Infection and immunity

authors： Schiff GM,Linnemann CC Jr,shea L,Lange B,Rotte T

更新日期：1975-04-01 00:00:00

abstract：:Most Helicobacter pylori strains express the BabA adhesin, which binds to ABO/Leb blood group antigens on gastric mucin and epithelial cells and is found more commonly in strains that cause peptic ulcers or gastric cancer, rather than asymptomatic infection. We and others have previously reported that in mice, gerbils...

journal_title：Infection and immunity

authors： Hansen LM,Gideonsson P,Canfield DR,Borén T,Solnick JV

更新日期：2017-05-23 00:00:00

abstract：:Infection with Cryptosporidium parvum, a ubiquitous protozoan parasite of virtually all mammals, can cause mild to severe diarrhea in immunocompetent hosts and life-threatening diarrhea in immunocompromised hosts. Passive immunotherapy of experimentally infected animals and naturally infected humans with hyperimmune b...

journal_title：Infection and immunity

authors： Fayer R,Guidry A,Blagburn BL

更新日期：1990-09-01 00:00:00

abstract：:We previously showed that cytotoxic necrotizing factor 1 (CNF1) contributes to Escherichia coli K1 invasion of human brain microvascular endothelial cells (HBMEC) and interacts with the receptor on the surface of HBMEC. CNF1 is the cytoplasmic protein, and it remains incompletely understood how CNF1 is secreted across...

journal_title：Infection and immunity

authors： Yu H,Kim KS

更新日期：2010-02-01 00:00:00

abstract：:Tuberculosis remains a leading killer worldwide, and new approaches for its treatment and prevention are urgently needed. This effort will benefit greatly from a better understanding of gene regulation in Mycobacterium tuberculosis, particularly with respect to this pathogen's response to its host environment. We exam...

journal_title：Infection and immunity

authors： Purkayastha A,McCue LA,McDonough KA

更新日期：2002-03-01 00:00:00

abstract：:It has been previously reported that although inducible nitric oxide synthase (iNOS) gene knockout (NOS2(-/-)) mice resolve Chlamydia trachomatis genital infection, the production of reactive nitrogen species (RNS) via iNOS protects a significant proportion of mice from hydrosalpinx formation and infertility. We now r...

journal_title：Infection and immunity

authors： Ramsey KH,Sigar IM,Rana SV,Gupta J,Holland SM,Byrne GI

更新日期：2001-12-01 00:00:00

abstract：:Anaplasma phagocytophilum is an obligate intracellular bacterium that infects myeloid cells in the mammalian host. Msp2 (p44) is the major immunodominant outer-membrane protein of these bacteria. We hypothesized that Msp2 acts as an adhesin for A. phagocytophilum entry into granulocytes. This potential role was invest...

journal_title：Infection and immunity

authors： Park J,Choi KS,Dumler JS

更新日期：2003-07-01 00:00:00

abstract：:Transcutaneous immunization (TCI) is a new method for vaccine delivery that has been shown to induce immunity relevant to enteric disease vaccines. We evaluated the clinical safety and immunogenicity of a recombinant subunit vaccine against enterotoxigenic Escherichia coli (ETEC) delivered by TCI. Adult volunteers rec...

journal_title：Infection and immunity

authors： Güereña-Burgueño F,Hall ER,Taylor DN,Cassels FJ,Scott DA,Wolf MK,Roberts ZJ,Nesterova GV,Alving CR,Glenn GM

更新日期：2002-04-01 00:00:00