Natural and immune antibodies for Vibrio fetus in serum and secretions of cattle.

abstract：:We determined the heavy (H)- and light (L)-chain variable (V) region nucleotide and translated amino acid sequences of the human immunoglobulin M(kappa) monoclonal antibody (MAb) 5E1, which is specific for the polysaccharide capsule of Escherichia coli K1 and Neisseria meningitidis group B (poly[alpha(2-->8)-N-acetyln...

journal_title：Infection and immunity

authors： Azmi FH,Lucas AH,Raff HV,Granoff DM

更新日期：1994-05-01 00:00:00

abstract：:Gamma interferon (IFN-γ) induces expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO1) in human epithelial cells, the permissive cells for the obligate intracellular bacterium Chlamydia trachomatis. IDO1 depletes tryptophan by catabolizing it to kynurenine with consequences for C. trachom...

journal_title：Infection and immunity

authors： Ibana JA,Belland RJ,Zea AH,Schust DJ,Nagamatsu T,AbdelRahman YM,Tate DJ,Beatty WL,Aiyar AA,Quayle AJ

更新日期：2011-11-01 00:00:00

abstract：:Lung dendritic cells were identified by immunohistochemistry in lung tissue sections from C57BL/6 mice. Following isolation from the lungs using CD11c magnetic beads, the flow cytometric analysis of I-A(b+) and CD11c(+) cells indicated a mixed population of dendritic cells at different stages of maturation, with most ...

journal_title：Infection and immunity

authors： Gonzalez-Juarrero M,Orme IM

更新日期：2001-02-01 00:00:00

abstract：:Type III and type VI secretion systems (T3SSs and T6SSs, respectively) are critical virulence determinants in several Gram-negative pathogens. In Burkholderia pseudomallei, the T3SS-3 and T6SS-1 clusters have been implicated in bacterial virulence in mammalian hosts. We recently discovered a regulatory cascade that co...

journal_title：Infection and immunity

authors： Chen Y,Wong J,Sun GW,Liu Y,Tan GY,Gan YH

更新日期：2011-08-01 00:00:00

abstract：:The outcome of coccidioidomycosis depends to a large extent on the effectiveness of the T-cell-mediated immune (CMI) response to the fungal pathogen. For this reason, identification of Coccidioides immitis antigens which stimulate T cells is important for understanding the nature of host defense against the organism a...

journal_title：Infection and immunity

authors： Kirkland TN,Thomas PW,Finley F,Cole GT

更新日期：1998-02-01 00:00:00

abstract：:Toxin A (TcdA) and toxin B (TcdB) are major virulence factors of Clostridium difficile. These two toxins intoxicate cultured cells by similar mechanisms, and TcdB generally is more potent than TcdA in cultured cells. The exact reason for this difference is unclear. Here, we report that the cellular effects of TcdA can...

journal_title：Infection and immunity

authors： He X,Sun X,Wang J,Wang X,Zhang Q,Tzipori S,Feng H

更新日期：2009-06-01 00:00:00

abstract：:Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections (UTIs). A murine UTI model has revealed an infection cascade whereby UPEC undergoes cycles of invasion of the bladder epithelium, intracellular proliferation in polysaccharide-containing biofilm-like masses called intracellular bact...

journal_title：Infection and immunity

authors： Anderson GG,Goller CC,Justice S,Hultgren SJ,Seed PC

更新日期：2010-03-01 00:00:00

abstract：:We studied the oligosaccharides (OS) of outer membrane lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis. OS from the LOS of an individual neisserial strain always eluted from Sephadex G-50S as multiple peaks; the polyacrylamide gel elution profiles were nearly identical to the polyacrylam...

journal_title：Infection and immunity

authors： Griffiss JM,O'Brien JP,Yamasaki R,Williams GD,Rice PA,Schneider H

更新日期：1987-08-01 00:00:00

abstract：:Lactoperoxidase catalyzes the oxidation of thiocyanate by hydrogen peroxide into hypothiocyanite, a reaction which can protect bacterial and mammalian cells from killing by hydrogen peroxide. The present study demonstrates, however, that lactoperoxidase in the presence of thiocyanate can actually potentiate the bacter...

journal_title：Infection and immunity

authors： Carlsson J,Edlund MB,Hänström L

更新日期：1984-06-01 00:00:00

abstract：:T cell-independent antibody responses develop rapidly, within 3 to 4 days, and are critical for preventing blood-borne pathogens from evolving into life-threatening infections. The interaction of BAFF, also known as BLyS, with its receptors BAFFR and TACI on B cells is critical for B cell homeostasis and function. Usi...

journal_title：Infection and immunity

authors： Dickinson GS,Sun G,Bram RJ,Alugupalli KR

更新日期：2014-01-01 00:00:00

abstract：:An effective vaccine for Vibrio cholerae is not yet available for use in the developing world, where the burden of cholera disease is highest. Characterizing the proteins that are expressed by V. cholerae in the human host environment may provide insight into the pathogenesis of cholera and assist with the development...

journal_title：Infection and immunity

authors： LaRocque RC,Krastins B,Harris JB,Lebrun LM,Parker KC,Chase M,Ryan ET,Qadri F,Sarracino D,Calderwood SB

更新日期：2008-09-01 00:00:00

abstract：:Shigella flexneri 2a is an invasive enteric pathogen that may produce diarrhea when ingested by human beings and subhuman primates. We have previously shown that shigella diarrhea correlates with water and electrolyte transport abnormalities in the jejunum and colon. Dysentery alone is associated only with colonic tra...

journal_title：Infection and immunity

authors： Kinsey MD,Formal SB,Dammin GJ,Giannella RA

更新日期：1976-08-01 00:00:00

abstract：:The in vivo induction of colony-stimulating activity (CSA) by N-acetylmuramyl-L-alanine-D-isoglutamine has been demonstrated recently. In this study we increased our understanding of this property by testing muramyl peptides of several structures and activities for their capacity to induce CSA in vivo. A comparison of...

journal_title：Infection and immunity

authors： Galelli A,Lefrancier P,Chedid L

更新日期：1984-11-01 00:00:00

abstract：:The 25-kb linear plasmid lp25 and one of the 28-kb linear plasmids (lp28-1) are required for experimental infection in Borrelia burgdorferi, the etiologic agent of Lyme disease. The loss of these plasmids either eliminates infectivity (lp25) or significantly increases the 50% infective dose during a 2-week infection p...

journal_title：Infection and immunity

authors： Labandeira-Rey M,Seshu J,Skare JT

更新日期：2003-08-01 00:00:00

abstract：:Shiga toxigenic Escherichia coli (STEC) strains are a diverse group of organisms capable of causing severe gastrointestinal disease in humans. Within the STEC family, eae-positive STEC strains, particularly those belonging to serogroups O157 and O111, appear to have greater virulence for humans. However, in spite of b...

journal_title：Infection and immunity

authors： Paton AW,Paton JC

更新日期：1999-11-01 00:00:00

abstract：:Intestinal epithelial activation of nuclear factor kappa B (NF-κB) exerts both detrimental and beneficial functions in response to various luminal insults, including ones associated with mucosa-associated pathogens. Gastrointestinal infection with enteropathogenic Escherichia coli (EPEC) causes severe injuries in epit...

journal_title：Infection and immunity

authors： Choi HJ,Kim J,Do KH,Park SH,Moon Y

更新日期：2013-06-01 00:00:00

abstract：:ATP and UTP have been proposed for use as therapeutic treatment of the abnormal ion transport in the airway epithelium in cystic fibrosis (CF), the most characteristic feature of which is permanent infection by Pseudomonas aeruginosa. As for diverse gram-negative bacteria, this pathogenic bacterium accumulates diffusi...

journal_title：Infection and immunity

authors： Saleh A,Figarella C,Kammouni W,Marchand-Pinatel S,Lazdunski A,Tubul A,Brun P,Merten MD

更新日期：1999-10-01 00:00:00

abstract：:Clinical trials of novel tuberculosis (TB) vaccines are expensive, while global resources for TB vaccine development are limited. Therefore, there is a need for robust and predictive preclinical data to support advancement of candidate vaccines into clinical trials. Here, we provide a rationale for using the nonhuman ...

journal_title：Infection and immunity

authors： Laddy DJ,Bonavia A,Hanekom WA,Kaushal D,Williams A,Roederer M,Seder RA,Sharpe S,Verreck FAW,Darrah PA

更新日期：2018-01-22 00:00:00

abstract：:The effects of tolerance to Escherichia coli endotoxin on the phagocytic and bactericidal activity of the hepatic reticuloendothelial system against viable E. coli were examined using ex vivo perfused rat livers. Livers were isolated from control and endotoxin-tolerant rats and perfused with a medium containing 5% hom...

journal_title：Infection and immunity

authors： Ruggiero G,Andreana A,Utili R,Galante D

更新日期：1980-03-01 00:00:00

abstract：:Fibronectin-binding proteins mediate Staphylococcus aureus internalization into nonphagocytic cells in vitro. We have investigated whether fibronectin-binding proteins are virulence factors in the pathogenesis of pneumonia by using S. aureus strain 8325-4 and isogenic mutants in which fibronectin-binding proteins were...

journal_title：Infection and immunity

authors： McElroy MC,Cain DJ,Tyrrell C,Foster TJ,Haslett C

更新日期：2002-07-01 00:00:00

abstract：:Ocular exposure of mice to live elementary bodies of Chlamydia trachomatis serovar A results in immunological sensitization of the mice. This reactivity is manifested by the development of early (5 h) and delayed-type (24 h) dermal reactivity and serovar-specific antibody formation against either live or irradiated (1...

journal_title：Infection and immunity

authors： Colley DG,Goodman TG,Barsoum IS

更新日期：1986-10-01 00:00:00

abstract：:Cholera toxin (CT) and related Escherichia coli enterotoxins LTI and LTIIb have a conserved hydrophobic region at the AB(5) interface postulated to be important for toxin assembly. Hydrophobic residue F223 in the A subunit of CT (CTA) as well as residues 174, L77, and T78 in the B subunit of CT (CTB) were replaced ind...

journal_title：Infection and immunity

authors： Tinker JK,Erbe JL,Hol WG,Holmes RK

更新日期：2003-07-01 00:00:00

abstract：:Previously, in our laboratory, we established a two-chamber system to study translocation of Enterococcus faecalis across monolayers of polarized human colon carcinoma-derived T84 cells. By using the same system in the present study, we now show that disruption of gelE of strain OG1RF, which also has a polar effect on...

journal_title：Infection and immunity

authors： Zeng J,Teng F,Murray BE

更新日期：2005-03-01 00:00:00

abstract：:In 2001, a bioterrorism attack involving Bacillus anthracis spore-laced letters resulted in 22 cases of inhalation anthrax, with five fatalities. This incident identified gaps in our health care system and precipitated a renewed interest in identifying both therapeutics and rapid diagnostic assays. To address those ga...

journal_title：Infection and immunity

authors： Rossi CA,Ulrich M,Norris S,Reed DS,Pitt LM,Leffel EK

更新日期：2008-12-01 00:00:00

abstract：:Streptococcus mutans, a major pathogen of dental caries, is considered one of the causative agents of infective endocarditis (IE). Recently, bacterial DNA encoding 120-kDa cell surface collagen-binding proteins (CBPs) has frequently been detected from S. mutans-positive IE patients. In addition, some of the CBP-positi...

journal_title：Infection and immunity

authors： Otsugu M,Nomura R,Matayoshi S,Teramoto N,Nakano K

更新日期：2017-11-17 00:00:00

abstract：:Attachment of Treponema denticola ATCC 35405 to laminin, a major basement membrane protein, and to other proteins was studied. Microdilution plates were coated with the proteins, and the attachment of T. denticola was measured by the enzyme-linked immunosorbent assay technique. Compared with bovine serum albumin (BSA)...

journal_title：Infection and immunity

authors： Haapasalo M,Singh U,McBride BC,Uitto VJ

更新日期：1991-11-01 00:00:00

abstract：:P.69 pertactin (P.69 Prn), an adhesion molecule from the causative agent of pertussis, Bordetella pertussis, is present in cellular and most acellular vaccines that are currently used worldwide. Although both humoral immunity and cellular immunity directed against P.69 Prn have been implicated in protective immune mec...

journal_title：Infection and immunity

authors： Stenger RM,Poelen MC,Moret EE,Kuipers B,Bruijns SC,Hoogerhout P,Hijnen M,King AJ,Mooi FR,Boog CJ,van Els CA

更新日期：2009-02-01 00:00:00

abstract：:Fibronectin binds to Streptococcus pyogenes, and this binding is inhibited by lipoteichoic acid (LTA). Previous studies have shown that LTA can be released from S. pyogenes by treatment with penicillin. Penicillin released LTA from both S. pyogenes and Staphylococcus aureus; however, the binding of fibronectin correla...

journal_title：Infection and immunity

authors： Nealon TJ,Beachey EH,Courtney HS,Simpson WA

更新日期：1986-02-01 00:00:00

abstract：:Twenty monoclonal antibodies have been prepared to the erythrocytes from CBA/Ca mice infected with the rodent malaria Plasmodium chabaudi. By immunofluorescence, 15 of these antibodies recognized parasite antigens expressed only during the development of mature trophozoites to schizonts and merozoites, 2 recognized pa...

journal_title：Infection and immunity

authors： Boyle DB,Newbold CI,Smith CC,Brown KN

更新日期：1982-10-01 00:00:00

abstract：:Several pathogenic fungal organisms enter eukaryotic cells and manipulate the host cell environment to favor their own growth and survival. Aspergillus fumigatus is a saprophytic fungus that causes invasive lung disease in the immunocompromised host. To determine whether A. fumigatus could enter eukaryotic cells, we s...

journal_title：Infection and immunity

authors： Wasylnka JA,Moore MM

更新日期：2002-06-01 00:00:00