Identification of a surrogate marker for infection in the African green monkey model of inhalation anthrax.

abstract：:Previous reports have demonstrated that heat-stable (A-type) capsule on piliated enterotoxigenic Escherichia coli enhances colonization of enterotoxigenic E. coli in the small intestine and enhances virulence of enterotoxigenic E. coli. In this report, four encapsulated enterotoxigenic E. coli strains and one encapsul...

journal_title：Infection and immunity

authors： Runnels PL,Moon HW

更新日期：1984-09-01 00:00:00

abstract：:Ehrlichia chaffeensis is a recently isolated minute gram-negative obligatory intracellular bacterium of monocytes/macrophages and is the etiologic agent of human monocytic ehrlichiosis. It is not known how macrophages respond when they encounter ehrlichiae in terms of cytokine production. In this study, we examined cy...

journal_title：Infection and immunity

authors： Lee EH,Rikihisa Y

更新日期：1996-10-01 00:00:00

abstract：:Host control of Coxiella burnetii infections is believed to be mediated primarily by activated monocytes/macrophages. The activation of macrophages by cytokines leads to the production of reactive oxygen intermediates (ROI) and reactive nitrogen intermediates (RNI) that have potent antimicrobial activities. The contri...

journal_title：Infection and immunity

authors： Brennan RE,Russell K,Zhang G,Samuel JE

更新日期：2004-11-01 00:00:00

abstract：:This work evaluated the kinetics of events that occur in the placenta of Calomys callosus after Toxoplasma gondii infection. Animals on the first day of pregnancy (dop) and virgin nonpregnant females were perorally infected with 20 cysts of T. gondii strain ME49. After 100 days of infection, the virgin animals were ma...

journal_title：Infection and immunity

authors： Ferro EA,Silva DA,Bevilacqua E,Mineo JR

更新日期：2002-12-01 00:00:00

abstract：:The virulence of Neisseria gonorrhoeae for chicken embryos can be modified in a predictable manner by the addition of microbial siderophores to the inoculum. "Meningobactin" and "gonobactin," siderophores isolated from iron-limited cultures of meningococci and gonococci, respectively, enhance the virulence of the rela...

journal_title：Infection and immunity

authors： Finkelstein RA,Yancey RJ

更新日期：1981-05-01 00:00:00

abstract：:Lipoteichoic acids (LTAs) belong to the immunostimulatory class of molecules of gram-positive bacteria (GPB). Previous investigations showed that the macrophage scavenger receptor (SR), a glycosylated trimeric transmembrane protein, binds directly to many GPB, possibly via LTA. SR binding to other ligands is dependent...

journal_title：Infection and immunity

authors： Greenberg JW,Fischer W,Joiner KA

更新日期：1996-08-01 00:00:00

abstract：:Oral or intravenous inoculation of previously unexposed juvenile and adult ferrets with Campylobacter jejuni uniformly resulted in intestinal colonization lasting 2 to 12 days. Disease varied from mild to moderate diarrhea, which resolved in 2 to 3 days. Orally infected animals developed agglutinin titers of 8 to 256 ...

journal_title：Infection and immunity

authors： Bell JA,Manning DD

更新日期：1990-06-01 00:00:00

abstract：:The hydrolysis of urea by ureases of oral bacteria in dental plaque can cause a considerable increase in plaque pH, which can inhibit the development of dental caries. There is also indirect evidence that urea metabolism may promote the formation of calculus and that ammonia release from urea could exacerbate periodon...

journal_title：Infection and immunity

authors： Morou-Bermudez E,Burne RA

更新日期：2000-12-01 00:00:00

abstract：:Nasopharyngeal colonization represents the initial interaction between Haemophilus influenzae and its human host. Factors that influence bacterial carriage likely affect transmission and incidence of infection. Therefore, we investigated host factors involved in limiting H. influenzae colonization in BALB/c mice, as c...

journal_title：Infection and immunity

authors： Zola TA,Lysenko ES,Weiser JN

更新日期：2009-08-01 00:00:00

abstract：:Fusobacterium nucleatum is closely associated with human periodontal diseases and may also be a causative agent in other infections, such as pericarditis, septic arthritis, and abscesses of tonsils and liver. Initiation and outcome of infective diseases depend critically on the host cell signaling system altered by th...

journal_title：Infection and immunity

authors： Uitto VJ,Baillie D,Wu Q,Gendron R,Grenier D,Putnins EE,Kanervo A,Firth JD

更新日期：2005-02-01 00:00:00

abstract：:Intestinal mucus is postulated to play a role in preventing colonization of the gastrointestinal tract by microbial pathogens. To evaluate the ability of both crude mucus and purified mucin, a glycoprotein of goblet cell origin, to inhibit mucosal adherence of enteric pathogens, we examined whether mucus and mucin der...

journal_title：Infection and immunity

authors： Drumm B,Roberton AM,Sherman PM

更新日期：1988-09-01 00:00:00

abstract：:The mechanism by which hamsters acquire resistance to yaws or frambesia is poorly understood. This investigation has shown that immune lymphoid cells (spleen and lymph node) could confer on hamsters resistance to infection with Treponema pertenue. Treatment of these immune cells with a specific antithymocyte serum (AT...

journal_title：Infection and immunity

authors： Chan JK,Schell RF,LeFrock JL

更新日期：1979-07-01 00:00:00

abstract：:The antigenic cross-reactivity between Treponema pallidum and several pathogenic members of the family Spirochaetaceae was examined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotting techniques. Blots of T. pallidum antigens were incubated with antiserum from rabbits infected or immunize...

journal_title：Infection and immunity

authors： Baker-Zander SA,Lukehart SA

更新日期：1984-10-01 00:00:00

abstract：:Cells of the marine fish pathogen Vibrio anguillarum 775 harboring a plasmid associated with virulence can grow unaffected in the presence of iron-binding compounds such as transferrin. In contrast, the growth of isogenic plasmidless derivatives is inhibited by the presence of iron chelators. Radioactive from (55Fe3+)...

journal_title：Infection and immunity

authors： Crosa JH,Hodges LL

更新日期：1981-01-01 00:00:00

abstract：:Legionella pneumophila, the gram-negative agent of Legionnaires' disease, possesses type IV pili and a type II protein secretion (Lsp) system, both of which are dependent upon the PilD prepilin peptidase. By analyzing multiple pilD mutants and various types of Lsp mutants as well as performing trans-complementation of...

journal_title：Infection and immunity

authors： Rossier O,Starkenburg SR,Cianciotto NP

更新日期：2004-01-01 00:00:00

abstract：:Incubation of large granular lymphocytes (LGL) with glutaraldehyde-fixed bacteria stimulated in the supernatant the production of interferon (IFN), which proved to be mainly IFN-gamma. Even though IFN-gamma was produced upon exposure of LGL to bacteria, anti-IFN-gamma antibodies failed to interfere with induction of c...

journal_title：Infection and immunity

authors： Tarkkanen J,Saksela E

更新日期：1991-08-01 00:00:00

abstract：:B-cell-deficient mice were prepared by administration of rabbit anti-mouse-mu antiserum to newborn animals within 12 h of birth onwards. Such immunodeficient animals, along with the normal controls, were infected intravenously with Cryptococcus neoformans. There was no difference in the mortality pattern, viable count...

journal_title：Infection and immunity

authors： Monga DP,Kumar R,Mohapatra LN,Malaviya AN

更新日期：1979-10-01 00:00:00

abstract：:Binding of Escherichia coli strain 431 heat-stable enterotoxin (STa) and activation of intestinal particulate guanylate cyclase by E. coli STa were studied with rat intestinal epithelial cells and brush border membranes (BBMs). The rates of guanylate cyclase stimulation by 431 STa in cells and BBMs were rapid, with ma...

journal_title：Infection and immunity

authors： Dreyfus LA,Robertson DC

更新日期：1984-11-01 00:00:00

abstract：:The nucleotide sequences of three previously undescribed Pseudomonas aeruginosa pilin structural genes are presented. Comparisons of deduced pilin primary structure and flanking DNA sequence allowed placement of these and six previously published sequences into one of two groups. Epitope mapping, using overlapping imm...

journal_title：Infection and immunity

authors： Castric PA,Deal CD

更新日期：1994-02-01 00:00:00

abstract：:The virulence and fitness in vivo of the major human pathogen Staphylococcus aureus are associated with a cell-to-cell signaling mechanism known as quorum sensing (QS). QS coordinates the production of virulence factors via the production and sensing of autoinducing peptide (AIP) signal molecules by the agr locus. Her...

journal_title：Infection and immunity

authors： Pollitt EJ,West SA,Crusz SA,Burton-Chellew MN,Diggle SP

更新日期：2014-03-01 00:00:00

abstract：:During bacterial infection of the bovine mammary gland, large numbers of leukocytes migrate into the udder, resulting in the establishment of a host response against the pathogen. Currently, the specific leukocyte populations mediating this immune response are not well defined. In the studies described here, we analyz...

journal_title：Infection and immunity

authors： Soltys J,Quinn MT

更新日期：1999-12-01 00:00:00

abstract：:Brucellosis is a bacterial disease of animals and humans. Brucella abortus barely activates the innate immune system at the onset of infection, and this bacterium is resistant to the microbicidal action of complement. Since complement stands as the first line of defense during bacterial invasions, we explored the role...

journal_title：Infection and immunity

authors： González-Espinoza G,Barquero-Calvo E,Lizano-González E,Alfaro-Alarcón A,Arias-Gómez B,Chaves-Olarte E,Lomonte B,Moreno E,Chacón-Díaz C

更新日期：2018-09-21 00:00:00

abstract：:We studied the oligosaccharides (OS) of outer membrane lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis. OS from the LOS of an individual neisserial strain always eluted from Sephadex G-50S as multiple peaks; the polyacrylamide gel elution profiles were nearly identical to the polyacrylam...

journal_title：Infection and immunity

authors： Griffiss JM,O'Brien JP,Yamasaki R,Williams GD,Rice PA,Schneider H

更新日期：1987-08-01 00:00:00

abstract：:Monoclonal antibodies against Ureaplasma urealyticum serotype 4 were produced by immunizing BALB/c mice with whole-cell antigens of the U. urealyticum serotype 4 reference strain. Ten monoclonal antibodies differentiated into two groups were found: one group included five monoclonal antibodies recognizing a band in im...

journal_title：Infection and immunity

authors： Cheng X,Naessens A,Lauwers S

更新日期：1993-05-01 00:00:00

abstract：:In evolving to an obligate intracellular niche, Chlamydia has streamlined its genome by eliminating superfluous genes as it relies on the host cell for a variety of nutritional needs like amino acids. However, Chlamydia can experience amino acid starvation when the human host cell in which the bacteria reside is expos...

journal_title：Infection and immunity

authors： Ouellette SP,Rueden KJ,Rucks EA

更新日期：2016-08-19 00:00:00

abstract：:In vivo expression of pili by Escherichia coli in the urine of 41 adults with lower urinary tract infections was analyzed by immunostaining with polyclonal antiserum to type 1 and P pili. Type 1 pili were detected in 31 of 41 urine specimens, while P pili were detected in 6 of 18 specimens. The piliation status of bac...

journal_title：Infection and immunity

authors： Kisielius PV,Schwan WR,Amundsen SK,Duncan JL,Schaeffer AJ

更新日期：1989-06-01 00:00:00

abstract：:A chemically defined medium developed for Neisseria gonorrhoeae was modified to support the growth of Campylobacter jejuni and Campylobacter coli. A total of 76 isolates of C. jejuni and 14 isolates of C. coli were tested on this medium, which was designated Campylobacter defined medium (CDM), over a 3-month period. A...

journal_title：Infection and immunity

authors： Tenover FC,Knapp JS,Patton C,Plorde JJ

更新日期：1985-05-01 00:00:00

abstract：:Hydrosalpinx induction in mice by Chlamydia muridarum infection, a model that has been used to study C. trachomatis pathogenesis in women, is known to depend on the cryptic plasmid that encodes eight genes designated pgp1 to pgp8. To identify the plasmid-encoded pathogenic determinants, we evaluated C. muridarum trans...

journal_title：Infection and immunity

authors： Liu Y,Huang Y,Yang Z,Sun Y,Gong S,Hou S,Chen C,Li Z,Liu Q,Wu Y,Baseman J,Zhong G

更新日期：2014-12-01 00:00:00

abstract：:Bacterial recognition of host sialic acid-containing receptors plays an important role in microbial colonization of the human oral cavity. The sialic acid-binding adhesin of Streptococcus gordonii DL1 was previously associated with the hsa gene encoding a 203-kDa protein. The predicted protein sequence consists of an ...

journal_title：Infection and immunity

authors： Takahashi Y,Yajima A,Cisar JO,Konishi K

更新日期：2004-07-01 00:00:00

abstract：:Earlier work had shown that a collection of anaerobic bacteria, in conjunction with facultative anaerobes, may be implanted into germfree mice, thereby rendering the animals "normal" with respect to a variety of parameters tested. The present experiments indicate that a different collection of anaerobic bacteria, isol...

journal_title：Infection and immunity

authors： Freter R,Abrams GD

更新日期：1972-08-01 00:00:00