Efficient B cell responses to Borrelia hermsii infection depend on BAFF and BAFFR but not TACI.

abstract：:An immunological assay utilizing double-diffusion principles was developed for identification of Pseudomonas aeruginosa mutants deficient in toxin A. Mutations were chemically induced, and mutants were isolated from P. aeruginosa strain PA103. Quantitative assays, both enzymatic and immunological, indicated that five ...

journal_title：Infection and immunity

authors： Ohman DE,Sadoff JC,Iglewski BH

更新日期：1980-06-01 00:00:00

abstract：:Cryptosporidial infections in severe combined immune deficient (SCID) mice produce a chronic disease state which in the later stages leads to extraintestinal involvement and hepatic dysfunction. To further characterize the infection dynamics in this model and monitor the changes in the hepatic system, a dose titration...

journal_title：Infection and immunity

authors： Mead JR,Ilksoy N,You X,Belenkaya Y,Arrowood MJ,Fallon MT,Schinazi RF

更新日期：1994-05-01 00:00:00

abstract：:Cytokine mRNA expression in biopsies of Mycobacterium ulcerans-infected human tissue was investigated using real-time PCR, and the findings were correlated with the clinical stages of disease and histopathologies. A broad range of cytokine mRNAs were detected in 16 early nodules and 28 late-stage ulcers, including tho...

journal_title：Infection and immunity

authors： Phillips R,Horsfield C,Mangan J,Laing K,Etuaful S,Awuah P,Nyarko K,Osei-Sarpong F,Butcher P,Lucas S,Wansbrough-Jones M

更新日期：2006-05-01 00:00:00

abstract：:Numerous bacterial pathogens use type III secretion systems (T3SSs) or T4SSs to inject or translocate virulence proteins into eukaryotic cells. Several different reporter systems have been developed to measure the translocation of these proteins. In this study, a peptide tag-based reporter system was developed and use...

journal_title：Infection and immunity

authors： Garcia JT,Ferracci F,Jackson MW,Joseph SS,Pattis I,Plano LR,Fischer W,Plano GV

更新日期：2006-10-01 00:00:00

abstract：:In a previous report (Y. Ohmori, S. Hanazawa, S. Amano, T. Miyoshi, K. Hirose, and S. Kitano, infect. Immun. 55:947-954, 1987), we showed that human gingival fibroblasts spontaneously produce thymocyte-activating factor (FTAF), which stimulates mitogen-induced thymocyte proliferation. In the present study, we examined...

journal_title：Infection and immunity

authors： Hanazawa S,Hirose K,Ohmori Y,Amano S,Kitano S

更新日期：1988-01-01 00:00:00

abstract：:Gamma interferon (IFN-gamma)-primed human gingival fibroblasts (HGF) have been shown to produce higher levels of interleukin-8 (IL-8) upon stimulation with bacterial products and inflammatory cytokines than nonprimed controls. In this study, we examined whether priming of HGF with IFN-gamma up-regulates IL-8 productio...

journal_title：Infection and immunity

authors： Tamai R,Sakuta T,Matsushita K,Torii M,Takeuchi O,Akira S,Akashi S,Espevik T,Sugawara S,Takada H

更新日期：2002-03-01 00:00:00

abstract：:Ehrlichia chaffeensis and Anaplasma phagocytophilum are agents of human monocytic and granulocytic ehrlichioses, respectively. They are extremely sensitive to mechanical stress and are pleomorphic gram-negative bacteria. Membrane incorporation of cholesterol from the eukaryotic host is known to be essential for other ...

journal_title：Infection and immunity

authors： Lin M,Rikihisa Y

更新日期：2003-09-01 00:00:00

abstract：:Helicobacter pylori infection is thought to be involved in the development of several gastric diseases. Two H. pylori virulence factors (vacuolating cytotoxin A and cytotoxin-associated gene A) reportedly interact with lipid rafts in gastric epithelial cells. The role of Toll-like receptor (TLR)-mediated signaling in ...

journal_title：Infection and immunity

authors： Lu DY,Chen HC,Yang MS,Hsu YM,Lin HJ,Tang CH,Lee CH,Lai CK,Lin CJ,Shyu WC,Lin FY,Lai CH

更新日期：2012-05-01 00:00:00

abstract：:An Escherichia coli oligonucleotide microarray based on three sequenced genomes was validated for comparative genomic microarray hybridization and used to study the diversity of E. coli O157 isolates from human infections and food and animal sources. Among 26 test strains, 24 (including both Shiga toxin [Stx]-positive...

journal_title：Infection and immunity

authors： Wu G,Carter B,Mafura M,Liebana E,Woodward MJ,Anjum MF

更新日期：2008-02-01 00:00:00

abstract：:Chlamydia trachomatis serovar L2 is an obligate intracellular bacterium which is internalized in target epithelial cells by endocytosis and resides within a membrane-bound vesicle. Over the next several hours following entry, individual serovar L2-containing vesicles fuse with one another to form a single membrane-bou...

journal_title：Infection and immunity

authors： Schramm N,Bagnell CR,Wyrick PB

更新日期：1996-04-01 00:00:00

abstract：:Polymorphoneutrophils (PMNs) are important effector cells in host defense against pneumonia. However, PMNs can also induce inflammation and tissue damage. To investigate the contribution of PMNs to host defense against pneumococcal pneumonia, we determined the effect of the PMN-depleting rat monoclonal antibody RB6-8C...

journal_title：Infection and immunity

authors： Marks M,Burns T,Abadi M,Seyoum B,Thornton J,Tuomanen E,Pirofski LA

更新日期：2007-04-01 00:00:00

abstract：:The lungs of conventional rats with chronic pneumonia contained Streptobacillus moniliformis and Mycoplasma pulmonis. These organisms singly and in combination failed to produce lung disease when inoculated into specific pathogen-free rats. On the other hand, diseased lung homogenate not containing cultivable organism...

journal_title：Infection and immunity

authors： Gay FW,Maguire ME,Baskerville A

更新日期：1972-07-01 00:00:00

abstract：:Formation of compact colonies of Staphylococcus aureus in serum-soft agar is mainly a result of a reaction between protein A and the Fc-part of immunoglobulin G and not a clumping factor-fibrinogen reaction. ...

journal_title：Infection and immunity

authors： Forsum U,Forsgren A,Hjelm E

更新日期：1972-10-01 00:00:00

abstract：:Pili have been demonstrated to be the adhesins of Pseudomonas aeruginosa for mouse epidermal cells. The mechanisms of adhesion of P. aeruginosa to mouse epidermal cells was studied by using four mutants derived from a single strain: flagellated and piliated (F+P+), flagellated and nonpiliated (F+P-), nonflagellated an...

journal_title：Infection and immunity

authors： Sato H,Okinaga K

更新日期：1987-08-01 00:00:00

abstract：:The interaction of plasma fibronectin with C1q of the complement system has been demonstrated in the past several years. In addition, the antibody-independent binding of C1q to bacteria, as well as the binding of plasma fibronectin to bacteria, is well documented. This study examines whether the binding of C1q to bact...

journal_title：Infection and immunity

authors： Sorvillo JM,Pearlstein E

更新日期：1985-09-01 00:00:00

abstract：:A system is described for studying adoptive immunity to tuberculosis in syngeneic mice. Donor mice were immunized with 10(4) BCG intravenously, and lymphoid cells were harvested 28 days later. Adoptive immunity was measured in recipient mice in terms of the inhibition of growth of BCG in the liver and spleen following...

journal_title：Infection and immunity

authors： Lefford MJ

更新日期：1975-06-01 00:00:00

abstract：:A single intradermal administration of recombinant interleukin-7 (IL-7) has been shown to aggravate the course of murine schistosomiasis, to favor the development of Th2-associated antibodies specific for the parasite, and to alter migration kinetics and/or migratory route of the parasite within its vertebrate host. H...

journal_title：Infection and immunity

authors： Wolowczuk I,Nutten S,Roye O,Delacre M,Capron M,Murray RM,Trottein F,Auriault C

更新日期：1999-08-01 00:00:00

abstract：:Mast cell-deficient W/Wv mice and their mast cell-sufficient littermates were given infections of Trichinella spiralis. W/Wv mice were slower than their littermates to expel adult T. spiralis. Repair of the mast cell deficiency of W/Wv mice by bone marrow grafting was accompanied by accelerated expulsion of T. spirali...

journal_title：Infection and immunity

authors： Ha TY,Reed ND,Crowle PK

更新日期：1983-07-01 00:00:00

abstract：:The biochemical properties of polymorphonuclear neutrophils from blood and peritoneal exudates of rabbits were compared. All enzymes measured showed almost identical activities in both types of cells, except for alkaline phosphodiesterase, the activity of which was seven times higher in peritoneal neutrophils. During ...

journal_title：Infection and immunity

authors： Takamori K,Yamashita T

更新日期：1980-08-01 00:00:00

abstract：:Escherichia coli F-18 is a human fecal isolate that makes type 1 fimbriae, encoded by the fim gene cluster, and is an excellent colonizer of the streptomycin-treated mouse intestine. E. coli F-18 fimA::tet, lacking type 1 fimbriae, was constructed by bacteriophage P1 transduction of the fim region of the E. coli K-12 ...

journal_title：Infection and immunity

authors： Sweeney NJ,Klemm P,McCormick BA,Moller-Nielsen E,Utley M,Schembri MA,Laux DC,Cohen PS

更新日期：1996-09-01 00:00:00

abstract：:Feline leukemia-sarcoma group-specific antigens were located in human embryo cells infected with feline leukemia and feline sarcoma viruses. This was done by using the fluorescent-antibody and enzyme-labeled antibody techniques at both light and electron microscopic levels. The antigens were found to be exclusively in...

journal_title：Infection and immunity

authors： Ubertini TR

更新日期：1972-03-01 00:00:00

abstract：:The purpose of the present study was to analyze Chlamydia pneumoniae-induced, antigen-specific, cell-mediated immunity. Peripheral blood mononuclear cells of four persons infected with C. pneumoniae Kajaani 6 and 17 healthy volunteers were stimulated with antigen composed of whole elementary bodies of C. pneumoniae Ka...

journal_title：Infection and immunity

authors： Surcel HM,Syrjälä H,Leinonen M,Saikku P,Herva E

更新日期：1993-05-01 00:00:00

abstract：:Leukosis viruses of seven subgroups were tested for oncogenicity in chickens susceptible to virus infection and to development of lymphoid leukosis (LL) tumors. All subgroup A viruses and the subgroup B virus tested produced a high incidence of LL and other related neoplasms. Viruses of subgroup C and RAV-61 of subgro...

journal_title：Infection and immunity

authors： Purchase HG,Okazaki W,Vogt PK,Hanafusa H,Burmester BR,Crittenden LB

更新日期：1977-02-01 00:00:00

abstract：:Mononuclear phagocytes provide the major habitat of intracellular bacteria, including Mycobacterium tuberculosis and Mycobacterium bovis. The capacity of B-cell stimulatory factor 2 (interleukin-6 [IL-6]) to activate tuberculostatic functions was investigated by using murine bone marrow-derived macrophages (BMM phi). ...

journal_title：Infection and immunity

authors： Flesch IE,Kaufmann SH

更新日期：1990-01-01 00:00:00

abstract：:Corynebacteriophage 782, a phage highly related to the beta family of corynebacteriophages but lacking a tox allele, was isolated from a nontoxinogenic clinical isolate of Corynebacterium diphtheriae. Phage 782 exhibits beta immunity but has a wider host range than beta, forming plaques on strains of C. ulcerans and C...

journal_title：Infection and immunity

authors： Cianciotto N,Groman N

更新日期：1985-07-01 00:00:00

abstract：:Acute lethality was induced in rabbits by the sequential injection of Propionibacterium acnes and lipopolysaccharide (LPS). P. acnes induced the infiltration of inflammatory cells into the liver lobules during the early phase, and LPS in the late phase caused death in association with pathological changes mimicking he...

journal_title：Infection and immunity

authors： Ikeda N,Mukaida N,Kaneko S,Fujioka N,Su S,Nariuchi H,Unoura M,Harada K,Nakanuma Y,Kobayashi K

更新日期：1995-12-01 00:00:00

abstract：:Bactericidal activity and binding of a 57,000-dalton cationic antimicrobial neutrophil granule protein (CAP57) are determined by the presence on bacteria of O-antigen polysaccharide chains and the availability of negatively charged groups in the lipid A region, the inner core region, or both regions of lipopolysacchar...

journal_title：Infection and immunity

authors： Farley MM,Shafer WM,Spitznagel JK

更新日期：1988-06-01 00:00:00

abstract：:Mice were protected against a lethal infection with Listeria monocytogenes when treated with low doses of an anti-CD3 monoclonal antibody (MAb). Injection of anti-CD3 MAb induced rapid production of endogenous tumor necrosis factor (TNF) in the spleens and endogenous gamma interferon (IFN-gamma) in the bloodstreams an...

journal_title：Infection and immunity

authors： Nakane A,Okamoto M,Asano M,Kohanawa M,Minagawa T

更新日期：1993-07-01 00:00:00

abstract：:F344 rats chronically infected with Ureaplasma parvum develop two distinct profiles: asymptomatic urinary tract infection (UTI) and UTI complicated by struvite urolithiasis. To identify factors that affect disease outcome, we characterized the temporal host immune response during infection by histopathologic analysis ...

journal_title：Infection and immunity

authors： Reyes L,Alvarez S,Allam A,Reinhard M,Brown MB

更新日期：2009-10-01 00:00:00

abstract：:A rapid and reproducible method of bacteriocin typing is described based on leakage of ultraviolet light-absorbing material (UVAM), detectable in supernatants of bacteriocin-sensitive cultures, by means of a spectrophotometer. The prerequisites for reproducible results, with nonsignificant fluctuations in standard err...

journal_title：Infection and immunity

authors： Farkas-Himsley H,Pagel A

更新日期：1977-04-01 00:00:00