Abstract:
:Mycoplasma salivarium cells propagated in PPLO broth (Difco Laboratories, Detroit, Mich.) supplemented with rabbit serum (10% [vol/vol]) and harvested by centrifugation were shown to contain rabbit immunoglobulin G (IgG) (approximately 4 to 10% of total cell proteins) and to produce IgM autoantibodies to IgG when inoculated into rabbits.
journal_name
Infect Immunjournal_title
Infection and immunityauthors
Watanabe T,Shibata K,Hasegawa Kdoi
10.1128/IAI.55.1.263-265.1987subject
Has Abstractpub_date
1987-01-01 00:00:00pages
263-5issue
1eissn
0019-9567issn
1098-5522journal_volume
55pub_type
杂志文章abstract::Recent reports have suggested that oral vaccination of mice against Helicobacter pylori is dependent on a Th1-mediated immune response. However, oral vaccination in mice neither induces sterilizing immunity nor leads to complete protection from disease. Therefore, in this study we investigated whether a systemic subcu...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.72.2.1029-1035.2004
更新日期:2004-02-01 00:00:00
abstract::A 95-kDa protein was isolated from Staphylococcus saprophyticus 7108 grown on dialysis membranes placed on the surface of brain heart infusion agar. Strain CCM883 did not produce this protein. Ultrathin sections revealed the presence of very thin, tuftlike, 50- to 75-nm-long structures on the surface of strain 7108, w...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.60.3.1055-1060.1992
更新日期:1992-03-01 00:00:00
abstract::Toxin preparations were obtained by growing Clostridium difficile VPI strain 10463 in 2-liter brain heart infusion dialysis flasks at 37 degrees C for 3 days. The initial step of the purification scheme involved ultrafiltration through an XM-100 membrane filter. Two toxic activities, designated toxins A and B, were se...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.35.3.1032-1040.1982
更新日期:1982-03-01 00:00:00
abstract::We have characterized the natural immune responses to the 19-kDa domain of merozoite surface protein 1 in individuals from an area of western Kenya in which malaria is holoendemic. We used the three known natural variant forms of the yeast-expressed recombinant 19-kDa fragment that are referred to as the E-KNG, Q-KNG,...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.64.7.2716-2723.1996
更新日期:1996-07-01 00:00:00
abstract::Glaesserella (Haemophilus) parasuis is a commensal bacterium of the upper respiratory tract in pigs and also the causative agent of Glässer's disease, which causes significant morbidity and mortality in pigs worldwide. Isolates are characterized into 15 serovars by their capsular polysaccharide, which has shown a corr...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00879-19
更新日期:2020-04-20 00:00:00
abstract::Adherence to fibrinogen and fibronectin plays a crucial role in Staphylococcus aureus experimental endocarditis. Previous genetic studies have shown that infection and carriage isolates do not systematically differ in their virulence-related genes, including genes conferring adherence, such as clfA and fnbA. We set ou...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.01274-09
更新日期:2010-04-01 00:00:00
abstract::Pasteurella multocida is the causative agent of fowl cholera in birds. In a previous study using signature-tagged mutagenesis, we identified a mutant, AL251, which was attenuated for virulence in mice and in the natural chicken host. Sequence analysis indicated that AL251 had an insertional inactivation of the gene wa...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.72.6.3436-3443.2004
更新日期:2004-06-01 00:00:00
abstract::Antibody rises to various virus subcomponents were measured by enzyme-linked immunosorbent assay in the paired sera of volunteers experimentally infected with human coronavirus 229E group viruses. Most of the antibody made during infection was directed against the virus surface projections, with only small amounts of ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.31.3.845-849.1981
更新日期:1981-03-01 00:00:00
abstract::Synthetic oligosaccharides derived from the capsular polysaccharide (PRP) of Haemophilus influenzae type b were conjugated to carrier proteins via a thioether linkage. Conjugates were made of trimeric and tetrameric ribose-ribitol-phosphate and tetanus toxoid or diphtheria toxin. All conjugates elicited anti-PRP antib...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.60.5.1826-1833.1992
更新日期:1992-05-01 00:00:00
abstract::Intimate attachment to the host cell leading to the formation of attaching and effacing (A/E) lesions is an essential feature of enterohemorrhagic Escherichia coli (EHEC) O157:H7 pathogenesis. In a related pathogen, enteropathogenic E. coli (EPEC), this activity is dependent upon translocation of the intimin receptor,...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.67.5.2389-2398.1999
更新日期:1999-05-01 00:00:00
abstract::Naegleria fowleri produces fatal meningoencephalitis in humans and in experimentally infected laboratory animals. The course of the disease in mice is dependent upon the infecting dose of amoebae, route of inoculation, and prior exposure to Naegleria antigens. DUB/ICR mice were immunized by various routes and antigen ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.16.3.817-820.1977
更新日期:1977-06-01 00:00:00
abstract::Neonates born to female guinea pigs of either a highly susceptible (C4D) or a resistant (Albany) strain, infected prior to or during pregnancy with a single dose of Treponema pallidum, showed in their sera from the first day of life immunoglobulin M (IgM) antibodies to T. pallidum, circulating immune complexes consist...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.60.1.271-277.1992
更新日期:1992-01-01 00:00:00
abstract::Secretory immunoglobulin A (SIgA) antibodies directed against the O antigen of lipopolysaccharide (LPS) are the primary determinants of mucosal immunity to gram-negative enteric pathogens. However, the underlying mechanisms by which these antibodies interfere with bacterial colonization and invasion of intestinal epit...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.00416-08
更新日期:2008-09-01 00:00:00
abstract::Localized juvenile periodontosis is associated with a defect of neutrophil chemotaxis that is characterized by selective depletion of a surface protein with a molecular mass of 110 kDa (GP110). Data on partial characterization of GP110 suggest that it is a glycoprotein which is enriched in Lys, Glu, His, Leu, and Ala ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.60.7.3015-3016.1992
更新日期:1992-07-01 00:00:00
abstract::Syphilis has been recognized as a disease since the late 1400s, yet there is no practical vaccine available. One impediment to the development of a vaccine is the lack of understanding of multiple reinfections in humans despite the development of robust immune responses during the first episode. It has been shown that...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.71.10.5605-5612.2003
更新日期:2003-10-01 00:00:00
abstract::Cytomegalovirus (CMV) infections are common in renal transplant recipients. We studied 23 recipients prospectively to determine whether infections by other herpes-group and non-herpes-group viruses were also present. Sera, obtained at the time of surgery and periodically thereafter, were tested for antibody to CMV, he...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.14.4.970-975.1976
更新日期:1976-10-01 00:00:00
abstract::Infection with the intracellular protozoan parasite Toxoplasma gondii causes serious public health problems and is of great economic importance worldwide. The micronemal protein MIC3, which is a potent adhesin of T. gondii, could be a significant candidate vaccine against toxoplasmosis. In this study, all CBA/J mice i...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.71.11.6222-6228.2003
更新日期:2003-11-01 00:00:00
abstract::We undertook a morphological and immunochemical comparison of purified outer membrane antigens from oral and nonoral isolates of Bacteroides asaccharolyticus. Electron micrographs of thin sections of whole bacteria revealed a compact, electron-dense capsule external to the outer membrane of oral strains. A loose, web-...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.27.2.589-596.1980
更新日期:1980-02-01 00:00:00
abstract::It is well established that activating-type Fc receptors for immunoglobulin G (FcgammaR), such as FcgammaRI and FcgammaRIII, are essential for inducing inflammatory responses. On the other hand, a unique inhibitory FcgammaR, FcgammaRIIB, inhibits intracellular signaling upon engagement of immunoglobulin G-immune compl...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.73.8.5048-5052.2005
更新日期:2005-08-01 00:00:00
abstract::We studied apoptosis in a human ileocecal adenocarcinoma tumor cell line (HCT-8) infected with Cryptosporidium parvum, from 2 to 72 h postinfection (h.p.i.). At 2 h.p.i., the percentage of annexin V-positive cells in the cell culture had increased to 10% compared to 2.5% in noninfected control culture; sorted infected...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.72.10.6061-6067.2004
更新日期:2004-10-01 00:00:00
abstract::The inhibitory effects of cortisol on cellular immunity were studied in vitro by using hamster peritoneal exudate cells. Two obligate, intracellular protozoa--Toxoplasma gondii and Besnoitia jellisoni-- were used to control for specificity of effects. Results indicate that immune lymphocytes specifically confer immuni...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.15.3.855-862.1977
更新日期:1977-03-01 00:00:00
abstract::Repeated immunizations of CF1 mice with irradiated noninfectious Trypanosoma cruzi trypomastigotes resulted in partial protection against infection with live parasites. It also induced a limited number of antibody species that were reactive in Western blots with trypomastigote but not with epimastigote or amastigote p...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.46.3.826-830.1984
更新日期:1984-12-01 00:00:00
abstract::The immunogenicity of the two major group 19 pneumococcal polysaccharides, types 19F and 19A, was studied in human volunteers. Antibody responses after vaccination with either 50 micrograms of type 19F polysaccharide, 50 micrograms of type 19A polysaccharide, or 25 micrograms of both polysaccharides premixed in a sing...
journal_title:Infection and immunity
pub_type: 临床试验,杂志文章
doi:10.1128/IAI.36.3.1261-1262.1982
更新日期:1982-06-01 00:00:00
abstract::Mice were infected with Chlamydia trachomatis (L2/434) and at various intervals after infection their lymphoid cells were tested directly for cytotoxic activity against Chlamydia-infected L929 cells. In a modified cell-mediated lympholysis assay, splenic, lymph node, and peritoneal exudate cells did not significantly ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.39.3.1271-1274.1983
更新日期:1983-03-01 00:00:00
abstract::Mesophilic Aeromonas hydrophila strains of serotype O34 typically express smooth lipopolysaccharide (LPS) on their surface. A single mutation in the gene that codes for UDP N-acetylgalactosamine 4-epimerase (gne) confers the O(-) phenotype (LPS without O-antigen molecules) on a strain in serotypes O18 and O34, but not...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.74.1.537-548.2006
更新日期:2006-01-01 00:00:00
abstract::Onchocerca volvulus, a human parasitic nematode, is the third leading cause of preventable blindness worldwide. This study describes the molecular cloning of a novel superoxide dismutase (SOD) from the parasite. This putative O. volvulus extracellular SOD (OvEcSOD) is 628 nucleotides (nt) long, including a 22-nt 5' sp...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.62.2.713-716.1994
更新日期:1994-02-01 00:00:00
abstract::Bordetella pertussis fimbriae are composed of a major subunit, Fim2 or Fim3, and the minor subunit FimD. Using immunoelectron microscopy, we provide evidence that FimD is located at the fimbrial tip. The role of FimD in colonization of the mouse respiratory tract was studied by using two fimbrial mutants: a mutant com...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.65.10.4222-4228.1997
更新日期:1997-10-01 00:00:00
abstract::The effects of infection with Rowson-Parr virus (RPV), an associated virus present in Friend virus (FV) preparations, on the splenic plaque-forming cell response to sheep red cells in adult mice and on the plaque-forming cell response of peritoneal cells in vitro have been investigated. The results support the hypothe...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.7.2.160-166.1973
更新日期:1973-02-01 00:00:00
abstract::Staphylococcus aureus and Salmonella enterica serovar Dublin invade osteoblasts and are causative agents of human bone disease. In the present study, we examined the ability of S. aureus and Salmonella serovar Dublin to induce the production of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by normal ...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/IAI.69.3.1581-1586.2001
更新日期:2001-03-01 00:00:00
abstract::Klebsiella pneumoniae is a leading cause of both community-acquired and nosocomial gram-negative-bacterial pneumonia. A further clinical complication of pulmonary K. pneumoniae infection is dissemination of bacteria from the lung into the peripheral blood, resulting in bacteremia concurrent with the localized pulmonar...
journal_title:Infection and immunity
pub_type: 杂志文章
doi:10.1128/iai.70.11.6310-6318.2002
更新日期:2002-11-01 00:00:00