Immunity against infection with Trypanosoma cruzi in mice correlates with presence of antibodies against three trypomastigote polypeptides.

abstract：:Cells infected by Rickettsia rickettsii, the causative agent of Rocky Mountain spotted fever, display unusual intracellular morphological changes characterized by dilatation of the membranes of the endoplasmic reticulum and outer nuclear envelope. These changes are consistent with those that might be expected to occur...

journal_title：Infection and immunity

authors： Silverman DJ,Santucci LA

更新日期：1988-12-01 00:00:00

abstract：:A total of 224 strains were serogrouped by coagglutination (COA) and serotyped by protein I enzyme-linked immunosorbent assay (ELISA). Of these strains, 61 were from patients with disseminated gonococcal infection, 21 were from patients with pelvic inflammatory disease, and 115 were from patients with uncomplicated go...

journal_title：Infection and immunity

authors： Sandstrom EG,Knapp JS,Buchanan TB

更新日期：1982-01-01 00:00:00

abstract：:Infection of resistant or susceptible mice with Trichuris muris provokes mesenteric lymph node responses which are polarized towards Th2 or Th1, respectively. These responses are well documented in the literature. In contrast, little is known about the local responses occurring within the infected intestine. Through m...

journal_title：Infection and immunity

authors： Datta R,deSchoolmeester ML,Hedeler C,Paton NW,Brass AM,Else KJ

更新日期：2005-07-01 00:00:00

abstract：:Antigen 2 (Ag2), a major immunoreactive component of Coccidioides immitis mycelium- and spherule-phase cell walls, was recently cloned in our laboratory and was shown to elicit T-cell responses in Coccidioides-immune mice. In this investigation, we evaluated recombinant Ag2 (rAg2) and PCR-generated Ag2 truncations for...

journal_title：Infection and immunity

authors： Zhu Y,Tryon V,Magee DM,Cox RA

更新日期：1997-08-01 00:00:00

abstract：:Tularemia is caused by the Gram-negative bacterial pathogen Francisella tularensis Infection of macrophages and their subsequent death are believed to play important roles in the progression of disease. Because complement is a particularly effective opsonin for Francisella, we asked whether complement-dependent uptake...

journal_title：Infection and immunity

authors： Brock SR,Parmely MJ

更新日期：2017-09-20 00:00:00

abstract：:Blastomyces dermatitidis is a thermally induced dimorphic fungus capable of causing lung and systemic infections in immunocompetent animal hosts. With the publication of genomic sequences from three different strains of B. dermatitidis and the development of RNA interference as a gene-silencing tool, it has become pos...

journal_title：Infection and immunity

authors： Krajaejun T,Wüthrich M,Gauthier GM,Warner TF,Sullivan TD,Klein BS

更新日期：2010-06-01 00:00:00

abstract：:The capacity of Candida albicans to switch reversibly between the white phenotype and the opaque phenotype is required for the fungus to mate. It also influences virulence during hematogenously disseminated candidiasis. We investigated the roles of the mating type loci (MTL) and white-opaque switching in the capacity ...

journal_title：Infection and immunity

authors： Solis NV,Park YN,Swidergall M,Daniels KJ,Filler SG,Soll DR

更新日期：2018-05-22 00:00:00

abstract：:Optimal growth conditions have been established for production of heat-labile enterotoxin (LT) by both porcine and human strains of enterotoxigenic (ENT(+)) Escherichia coli. There were no unusual growth factor requirements, and some strains produced fairly high levels of LT in a basal salts medium containing 0.5% glu...

journal_title：Infection and immunity

authors： Gilligan PH,Robertson DC

更新日期：1979-01-01 00:00:00

abstract：:Clostridium botulinum neurotoxins (BoNTs) are the most toxic proteins for humans. The current clostridial-derived vaccines against BoNT intoxication have limitations including production and accessibility. Conditions were established to express the soluble receptor binding domain (heavy-chain receptor [HCR]) of BoNT s...

journal_title：Infection and immunity

authors： Baldwin MR,Tepp WH,Pier CL,Bradshaw M,Ho M,Wilson BA,Fritz RB,Johnson EA,Barbieri JT

更新日期：2005-10-01 00:00:00

abstract：:The bacterium Listeria monocytogenes causes meningoencephalitis in humans. In rodents, listeriosis is associated with granulomatous lesions in the liver and the spleen, but not with meningoencephalitis. Here, infant rats were infected intracisternally to generate experimental listeric meningoencephalitis. Dose-depende...

journal_title：Infection and immunity

authors： Remer KA,Jungi TW,Fatzer R,Täuber MG,Leib SL

更新日期：2001-06-01 00:00:00

abstract：:An anti-glucosyltransferase serum was prepared against a pure enzyme preparation from Streptococcus sanguis OMZ 9, which synthesized both soluble and insoluble dextran. Sera, crude gamma globulins, and antibody fractions obtained after gel filtration on a Bio-Gel P200 column were used to study enzyme-antibody interact...

journal_title：Infection and immunity

authors： Klein JP,Schöller M,Frank RM

更新日期：1978-06-01 00:00:00

abstract：:Escherichia coli O157:H7 causes food and waterborne enteric infections that can result in hemorrhagic colitis and life-threatening hemolytic uremic syndrome. Intimate adherence of the bacteria to intestinal epithelial cells is mediated by intimin, but E. coli O157:H7 also possess several other putative adhesins, inclu...

journal_title：Infection and immunity

authors： Lloyd SJ,Ritchie JM,Rojas-Lopez M,Blumentritt CA,Popov VL,Greenwich JL,Waldor MK,Torres AG

更新日期：2012-03-01 00:00:00

abstract：:We have previously described (L. M. Vaughan, P. R. Smith, and T. J. Foster, Infect. Immun. 61:2172-2181, 1993) the construction of a kanamycin-resistant aromatic-dependent mutant of Aeromonas salmonicida, the causative agent of furunculosis, and its use as a live vaccine. Here we describe the construction of an unmark...

journal_title：Infection and immunity

authors： Marsden MJ,Vaughan LM,Foster TJ,Secombes CJ

更新日期：1996-09-01 00:00:00

abstract：:Most patients with juvenile periodontitis manifest serum antibodies, sometimes at very high titers, to antigens of Actinobacillus actinomycetemcomitans, but the antigens inducing the immune response have been only partly characterized. We separated A. actinomycetemcomitans serotype b cells into protein, lipopolysaccha...

journal_title：Infection and immunity

authors： Page RC,Sims TJ,Engel LD,Moncla BJ,Bainbridge B,Stray J,Darveau RP

更新日期：1991-10-01 00:00:00

abstract：:Vesicular stomatitis virus (VSV) infection of beige (bg/bg) mice induced levels of natural killer cytolytic activity comparable to that of uninfected normal bg/+ controls, but considerably less than natural killer activity in VSV-infected bg/+ mice. In contrast, VSV-infected bg/bg and bg/+ mice had essentially equival...

journal_title：Infection and immunity

authors： McKinnon KP,Hale AH,Ruebush MJ

更新日期：1981-04-01 00:00:00

abstract：:We previously reported that infection by Mycobacterium tuberculosis, the causative agent of tuberculosis, leads to secretion of alpha/beta interferon (IFN-alpha/beta). While IFN-alpha/beta ordinarily stimulates formation of signal transducer and stimulator of transcription-1 (STAT-1) homodimers and IFN-stimulated gene...

journal_title：Infection and immunity

authors： Prabhakar S,Qiao Y,Hoshino Y,Weiden M,Canova A,Giacomini E,Coccia E,Pine R

更新日期：2003-05-01 00:00:00

abstract：:Normal ICR mice were infected intravenously, intraperitoneally, or aerogenically with Pasteurella multocida strains isolated from a turkey (S68), calf (V90), or rabbit (J20) lung. Both the turkey and calf isolates were highly virulent for mice and multiplied logarithmically in the lungs, liver, and spleen, resulting i...

journal_title：Infection and immunity

authors： Collins FM,Niederbuhl CJ,Campbell SG

更新日期：1983-02-01 00:00:00

abstract：:The in vivo behavior of revertants of Staphylococcus aureus L-phase variants were studied in mice. The Giorgio strain of S. aureus was induced into L-phase variants by methicillin. After 13 serial passages in methicillin agar and six passages in antibiotic-free agar, reversion occurred. Six revertants, all phage untyp...

journal_title：Infection and immunity

authors： Watanakunakorn C,Glotzbecker C

更新日期：1975-06-01 00:00:00

abstract：:At pH 7.4 and in the presence of NaHCO3, human milk and bovine colostrum inhibited the growth of Escherichia coli O111. Adding sufficient iron to saturate the iron-binding capacity of the lactoferrin present in the milk or colostrum prevented bacteriostasis. At pH 6.8 neither molk nor colostrum inhibited E. coli 0111....

journal_title：Infection and immunity

authors： Griffiths E,Humphreys J

更新日期：1977-02-01 00:00:00

abstract：:A method was developed to test for the ability of Escherichia coli to adhere to isolated intestinal epithelial cells. Of the E. coli tested, those having either K88ac or K88ab antigens adhered to the cells, and those which did not have these antigens did not. Since some enteropathogenic E. coli did not have the abilit...

journal_title：Infection and immunity

authors： Wilson MR,Hohmann AW

更新日期：1974-10-01 00:00:00

abstract：:The var gene-encoded Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family is responsible for antigenic variation and sequestration of infected erythrocytes during malaria. We have previously grouped the 60 PfEMP1 variants of P. falciparum clone 3D7 into groups A and B/A (category A) and groups B, B/C, ...

journal_title：Infection and immunity

authors： Joergensen L,Turner L,Magistrado P,Dahlbäck MA,Vestergaard LS,Lusingu JP,Lemnge M,Salanti A,Theander TG,Jensen AT

更新日期：2006-12-01 00:00:00

abstract：:The ability of a pathogen to evade neutrophil phagocytic killing mechanisms is critically important for dissemination and establishment of a systemic infection. Understanding how pathogens overcome these innate defenses is essential for the development of optimal therapeutic strategies for invasive infections. CpsY is...

journal_title：Infection and immunity

authors： Allen JP,Neely MN

更新日期：2012-05-01 00:00:00

abstract：:A clone bank of Pasteurella haemolytica A1 was constructed by partial digestion of the genomic DNA with Sau3A and ligation of 5- to 10-kilobase-pair fragments into the BamHI site of the plasmid vector pBR322. After transformation into Escherichia coli K-12, a total of 4 X 10(3) recombinant clones was obtained. These w...

journal_title：Infection and immunity

authors： Lo RY,Shewen PE,Strathdee CA,Greer CN

更新日期：1985-12-01 00:00:00

abstract：:Bacteria alter their cell surface in response to changing environments, including those encountered upon invasion of a host during infection. One alteration that occurs in several Gram-positive pathogens is the presentation of cell wall-anchored components of the iron-regulated surface determinant (Isd) system, which ...

journal_title：Infection and immunity

authors： Farrand AJ,Haley KP,Lareau NM,Heilbronner S,McLean JA,Foster T,Skaar EP

更新日期：2015-09-01 00:00:00

abstract：:A set of four monoclonal antibodies was produced against a highly purified pepsin extract of type 5 streptococcal M protein. Three of the four antibodies cross-reacted with purified M proteins from heterologous serotypes and opsonized the respective heterologous organisms. Our studies suggest that monoclonal antibodie...

journal_title：Infection and immunity

authors： Dale JB,Beachey EH

更新日期：1984-10-01 00:00:00

abstract：:The adherence of 58 nontypeable Haemophilus influenzae isolates obtained from patients with otitis media or chronic obstructive pulmonary disease (COPD) and obtained from the throats of healthy individuals to Chang and NCI-H292 epithelial cells was compared. Otitis media isolates, but not COPD isolates, adhered signif...

journal_title：Infection and immunity

authors： van Schilfgaarde M,van Ulsen P,Eijk P,Brand M,Stam M,Kouame J,van Alphen L,Dankert J

更新日期：2000-08-01 00:00:00

abstract：:Salmonella enterica serovar Typhimurium causes self-limiting gastroenteritis in humans and a typhoid-like disease in mice that serves as a model for typhoid infections in humans. A critical step in Salmonella pathogenesis is the invasion of enterocytes and M cells of the small intestine via expression of a type III se...

journal_title：Infection and immunity

authors： Boddicker JD,Jones BD

更新日期：2004-04-01 00:00:00

abstract：:The smooth lipopolysaccharide complex of the outer surface of smooth Brucella abortus cells is believed to be the antigenic component involved in serological tests routinely used for the diagnosis of brucellosis. Sera from cattle vaccinated or infected with B. abortus generally contain antibody directed toward the smo...

journal_title：Infection and immunity

authors： Schurig GG,Jones LM,Speth SL,Berman DT

更新日期：1978-09-01 00:00:00

abstract：:Dendritic cell interactions with pathogenic microbes initiate and direct the development of subsequent adaptive responses. The protozoan pathogen Giardia lamblia infects the mammalian small intestine, leading to nutrient malabsorption and diarrhea but rarely causing inflammation. In order to begin to understand how th...

journal_title：Infection and immunity

authors： Kamda JD,Singer SM

更新日期：2009-02-01 00:00:00

abstract：:Two distinct monoclonal antibodies, one to pertussis toxin subunit S2, called 9G8, and another to subunits S2 and S3, called 11E6, were generated from the hybridomas of myeloma SP2/0 and spleen cells of BALB/c mice immunized mainly with the subunit S234 complex. Binding ability of 9G8 and 11E6 to the subunits was conf...

journal_title：Infection and immunity

authors： Sato H,Sato Y,Ito A,Ohishi I

更新日期：1987-04-01 00:00:00