Elicitation of natural killer cells in beige mice by infection with vesicular stomatitis virus.

abstract：:Protective immunity against pulmonary tuberculosis (TB) is characterized by the formation in the lungs of granulomas consisting of macrophages and activated T cells producing tumor necrosis factor alpha and gamma interferon, both required for the activation of the phagocytes. In 90% of immunocompetent humans, this res...

journal_title：Infection and immunity

authors： Kaplan G,Post FA,Moreira AL,Wainwright H,Kreiswirth BN,Tanverdi M,Mathema B,Ramaswamy SV,Walther G,Steyn LM,Barry CE 3rd,Bekker LG

更新日期：2003-12-01 00:00:00

abstract：:The hallmarks of pulmonary Mycobacterium tuberculosis infection are lung granulomas. These organized structures are composed of host immune cells whose purpose is to contain or clear infection, creating a complex hub of immune and bacterial cell activity, as well as limiting pathology in the lungs. Yet, given cellular...

journal_title：Infection and immunity

authors： Wong EA,Joslyn L,Grant NL,Klein E,Lin PL,Kirschner DE,Flynn JL

更新日期：2018-08-22 00:00:00

abstract：:Proteins were extracted at pH 2.5 from carefully washed brain homogenates of patients with subacute sclerosing panencephalitis. Immunoglobulin G was isolated from the extracts by gel filtration and immunoadsorbent chromatography and was 125I radioiodinated. The labeled immunoglobulin G was reacted with purified measle...

journal_title：Infection and immunity

authors： Weil ML,Norrby E,Itabashi HH,Wilson R,Tourtellotte WW,Heiner DC

更新日期：1979-04-01 00:00:00

abstract：:Three groups of cattle, each group comprising six animals, were inoculated intravenously with populations of bloodstream forms of Trypanosoma vivax. The first group received T. vivax clone ILDat 1.3 derived from an isolate from Nigeria, while the other two received T. vivax stocks IL 1875 or IL 2133 isolated from Coas...

journal_title：Infection and immunity

authors： Nantulya VM,Musoke AJ,Moloo SK

更新日期：1986-11-01 00:00:00

abstract：:The in vivo induction of colony-stimulating activity (CSA) by N-acetylmuramyl-L-alanine-D-isoglutamine has been demonstrated recently. In this study we increased our understanding of this property by testing muramyl peptides of several structures and activities for their capacity to induce CSA in vivo. A comparison of...

journal_title：Infection and immunity

authors： Galelli A,Lefrancier P,Chedid L

更新日期：1984-11-01 00:00:00

abstract：:Streptococcus pneumoniae remains a major causative agent of serious human diseases. The worldwide increase of antibiotic resistant strains revealed the importance of horizontal gene transfer in this pathogen, a scenario that results in the modulation of the species-specific gene pool. We investigated genomic variation...

journal_title：Infection and immunity

authors： Hakenbeck R,Balmelle N,Weber B,Gardès C,Keck W,de Saizieu A

更新日期：2001-04-01 00:00:00

abstract：:A secreted nuclease, SsnA, was identified in the virulent Streptococcus suis isolate SX332 and subsequently in each of the type strains of capsular serotypes 1 through 9. Screening of 258 porcine clinical isolates from surface (nasal mucosa or palatine tonsil) or internal (joint, brain or other internal organ) locatio...

journal_title：Infection and immunity

authors： Fontaine MC,Perez-Casal J,Willson PJ

更新日期：2004-02-01 00:00:00

abstract：:A 60-kilodalton (kDa) immunodominant antigen of Legionella pneumophila is a heat shock protein (HSP) of the GroEL class of HSPs. The gene (htpB) coding the 60-kDa protein was localized to a 3.2-kilobase DNA fragment of L. pneumophila cloned into pUC19 (pSH16) (P. S. Hoffman, C. A. Butler, and F. D. Quinn, Infect. Immu...

journal_title：Infection and immunity

authors： Hoffman PS,Houston L,Butler CA

更新日期：1990-10-01 00:00:00

abstract：:The symptoms of Lyme disease are caused by inflammation induced by species of the Borrelia burgdorferisensu lato complex. The various presentations of Lyme disease in the population suggest that differences exist in the intensity and regulation of the host response to the spirochete. Previous work has described correl...

journal_title：Infection and immunity

authors： Siebers EM,Liedhegner ES,Lawlor MW,Schell RF,Nardelli DT

更新日期：2020-10-19 00:00:00

abstract：:Human gingival fibroblasts were exposed in culture to cell extracts of different black-pigmented Bacteroides species, and their growth was monitored by determining thymidine uptake and counting cells. Of the Bacteroides species tested (B. gingivalis, B. asaccharolyticus, and B. intermedius), B. gingivalis gave the ext...

journal_title：Infection and immunity

authors： Larjava H,Uitto VJ,Eerola E,Haapasalo M

更新日期：1987-01-01 00:00:00

abstract：:Previous attempts to induce mucosal antibodies in rhesus monkeys by enteric immunization have resulted in only modest and short-lived responses, dominated by immunoglobulin M (IgM) antibodies in the plasma. In this study, two groups of rhesus monkeys were immunized intranasally three times at 2-week intervals with a b...

journal_title：Infection and immunity

authors： Russell MW,Moldoveanu Z,White PL,Sibert GJ,Mestecky J,Michalek S M

更新日期：1996-04-01 00:00:00

abstract：:We determined the heavy (H)- and light (L)-chain variable (V) region nucleotide and translated amino acid sequences of the human immunoglobulin M(kappa) monoclonal antibody (MAb) 5E1, which is specific for the polysaccharide capsule of Escherichia coli K1 and Neisseria meningitidis group B (poly[alpha(2-->8)-N-acetyln...

journal_title：Infection and immunity

authors： Azmi FH,Lucas AH,Raff HV,Granoff DM

更新日期：1994-05-01 00:00:00

abstract：:Haemophilus ducreyi, the etiologic agent of the sexually transmitted disease chancroid, has been shown to inhibit phagocytosis of both itself and secondary targets in vitro. Immunodepletion of LspA proteins from H. ducreyi culture supernatant fluid abolished this inhibitory effect, indicating that the LspA proteins ar...

journal_title：Infection and immunity

authors： Mock JR,Vakevainen M,Deng K,Latimer JL,Young JA,van Oers NS,Greenberg S,Hansen EJ

更新日期：2005-12-01 00:00:00

abstract：:An experimental model of coxsackievirus B3 infection in newborn mice was utilized to examine the protective role of antiviral antibodies and an interferon inducer, polyinosinic acid-polycytidylic acid [poly(I:C)]. Subcutaneous administration to the infected mice of specific antiviral antibodies resulted in significant...

journal_title：Infection and immunity

authors： Cho CT,Feng KK,McCarthy VP,Lenahan MF

更新日期：1982-08-01 00:00:00

abstract：:Neisseria gonorrhoeae is an obligate human pathogen that causes the common sexually transmitted infection gonorrhea. Gonococcal infections cause significant morbidity, particularly among women, as the organism ascends to the upper reproductive tract, resulting in pelvic inflammatory disease, ectopic pregnancy, and inf...

journal_title：Infection and immunity

authors： Hollander A,Mercante AD,Shafer WM,Cornelissen CN

更新日期：2011-12-01 00:00:00

abstract：:Guinea pig peritoneal or alveolar macrophages were inoculated with Mycoplasma pneumoniae cells. Extracellular mycoplasms were killed by complement treatment, and the effect of macrophage action on the number of the remaining viable mycoplasmas was observed. The complement killing was to some extent inhibited by the pr...

journal_title：Infection and immunity

authors： Erb P,Bredt W

更新日期：1979-07-01 00:00:00

abstract：:Several pathogenic fungal organisms enter eukaryotic cells and manipulate the host cell environment to favor their own growth and survival. Aspergillus fumigatus is a saprophytic fungus that causes invasive lung disease in the immunocompromised host. To determine whether A. fumigatus could enter eukaryotic cells, we s...

journal_title：Infection and immunity

authors： Wasylnka JA,Moore MM

更新日期：2002-06-01 00:00:00

abstract：:Cysteine proteases, including Arg-gingipain of Porphyromonas gingivalis, have been implicated as important virulence factors in periodontal diseases. These enzymes are also involved in the hemagglutinating activity of the organisms. In order to determine the role of proteases in the colonization of the gingival margin...

journal_title：Infection and immunity

authors： Tokuda M,Duncan M,Cho MI,Kuramitsu HK

更新日期：1996-10-01 00:00:00

abstract：:Members of the babesial rhoptry-associated protein 1 (RAP-1) family express surface-exposed B-cell epitopes and are candidate antigens for vaccine development. The relationship between rap-1 genomic polymorphism and surface-exposed B-cell epitope expression was analyzed by comparison of biological clones of Mexico str...

journal_title：Infection and immunity

authors： Suarez CE,McElwain TF,Echaide I,Torioni de Echaide S,Palmer GH

更新日期：1994-08-01 00:00:00

abstract：:Human granulocytic ehrlichiosis (HGE) is an emerging febrile systemic disease caused by the HGE agent, an obligatory intracellular bacterium of granulocytes. The pathogenicity- and immunity-related mechanisms of HGE are unknown. In this study, several cytokines generated in human peripheral blood leukocytes (PBLs) inc...

journal_title：Infection and immunity

authors： Kim HY,Rikihisa Y

更新日期：2000-06-01 00:00:00

abstract：:Bovine NK cells have recently been characterized and the present study describes the interaction between NK cells, antigen-presenting cells, and secreted mycobacterial proteins. Gamma interferon (IFN-gamma) production by NK cells was seen in approximately 30% of noninfected calves in response to the Mycobacterium tube...

journal_title：Infection and immunity

authors： Olsen I,Boysen P,Kulberg S,Hope JC,Jungersen G,Storset AK

更新日期：2005-09-01 00:00:00

abstract：:Human serum at low concentrations inhibits the growth of Cryptococcus neoformans in vitro. Fractionation of serum yielded a purified inhibitory protein with a molecular mass of approximately 81.8 kDa, a pI of approximately 6.2, and an amino acid sequence that matched that of human transferrin. The inhibitory activity ...

journal_title：Infection and immunity

authors： Sridhar S,Ahluwalia M,Brummer E,Stevens DA

更新日期：2000-06-01 00:00:00

abstract：:Little data are available regarding L-form phagocyte interactions. Due to difficulty with more conventional methods, a serum-free technique of surface phagocytosis employing cellulose ester micropore filters, fluorochrome staining, and reflecting fluorescence microscopy was developed. Intracellular localization of L-f...

journal_title：Infection and immunity

authors： Harwick HJ,Barajas L,Montgomerie JZ,Kalmanson GM,Guze LB

更新日期：1972-06-01 00:00:00

abstract：:The Salmonella typhimurium gene for Mn-cofactored superoxide dismutase (sodA) was cloned by complementation of an Escherichia coli sodA sodB mutant for growth on minimal medium. Sequence analysis revealed an open reading frame of 618 bp encoding a polypeptide with 97% identity to E. coli SodA. A S. typhimurium sodA mu...

journal_title：Infection and immunity

authors： Tsolis RM,Bäumler AJ,Heffron F

更新日期：1995-05-01 00:00:00

abstract：:Cryptosporidial infections in severe combined immune deficient (SCID) mice produce a chronic disease state which in the later stages leads to extraintestinal involvement and hepatic dysfunction. To further characterize the infection dynamics in this model and monitor the changes in the hepatic system, a dose titration...

journal_title：Infection and immunity

authors： Mead JR,Ilksoy N,You X,Belenkaya Y,Arrowood MJ,Fallon MT,Schinazi RF

更新日期：1994-05-01 00:00:00

abstract：:The antihistoplasma activity of recombinant murine gamma interferon (rMuIFN-gamma)-treated macrophages of the RAW 264.7 cell line depends on the generation of nitric oxide (NO.) from L-arginine. Macrophages of the P388D1 cell line treated with rMuIFN-gamma do not produce NO. or inhibit the intracellular growth of Hist...

journal_title：Infection and immunity

authors： Lane TE,Otero GC,Wu-Hsieh BA,Howard DH

更新日期：1994-04-01 00:00:00

abstract：:Naegleria fowleri produces fatal meningoencephalitis in humans and in experimentally infected laboratory animals. The course of the disease in mice is dependent upon the infecting dose of amoebae, route of inoculation, and prior exposure to Naegleria antigens. DUB/ICR mice were immunized by various routes and antigen ...

journal_title：Infection and immunity

authors： John DT,Weik RR,Adams AC

更新日期：1977-06-01 00:00:00

abstract：:Engerotoxins isolated from Vibrio cholerae and toxigenic Escherichia coli cause permeability alterations in rabbit skin. Firm induration and erythema are observed within 18 to 24 h, and visualization of the reaction may be enhanced by intravenous injection of Pontamine sky blue dye. Two skin permeability factors (PF) ...

journal_title：Infection and immunity

authors： Sandefur PD,Peterson JW

更新日期：1976-09-01 00:00:00

abstract：:Random minitransposon mutagenesis was used to identify genes involved in the survival of Bordetella bronchiseptica within eukaryotic cells. One of the mutants which exhibited a reduced ability to survive intracellularly harbored a minitransposon insertion in a locus (ris) which displays a high degree of homology to tw...

journal_title：Infection and immunity

authors： Jungnitz H,West NP,Walker MJ,Chhatwal GS,Guzmán CA

更新日期：1998-10-01 00:00:00

abstract：:To determine whether an ongoing response to Leishmania major would affect the response to a non-cross-reacting, non-leishmanial antigen, susceptible BALB/c mice and resistant C3H mice were infected with L. major parasites expressing Escherichia coli beta-galactosidase (beta-GAL); this parasite was designated L. major-...

journal_title：Infection and immunity

authors： Chakkalath HR,Siddiqui AA,Shankar AH,Dobson DE,Beverley SM,Titus RG

更新日期：2000-02-01 00:00:00