Isolation of skin permeability factors from culture filtrates of Salmonella typhimurium.

abstract：:We have previously shown that a pneumococcal surface protein A (PspA)-based vaccine containing DNA plasmid encoding the Flt3 ligand (FL) gene (pFL) as a nasal adjuvant prevented nasal carriage of Streptococcus pneumoniae. In this study, we further investigated the safety and efficacy of this nasal vaccine for the indu...

journal_title：Infection and immunity

authors： Kataoka K,Fujihashi K,Oma K,Fukuyama Y,Hollingshead SK,Sekine S,Kawabata S,Ito HO,Briles DE,Oishi K

更新日期：2011-07-01 00:00:00

abstract：:Alveolar bone resorption can be induced in specific-pathogen-free mice by oral infection with Porphyromonas gingivalis (P. J. Baker, R. T. Evans, and D. C. Roopenian, Arch. Oral Biol. 39:1035-1040, 1994). Here we used a mouse strain, C57BL/6J, which is relatively resistant to P. gingivalis-induced bone loss to examine...

journal_title：Infection and immunity

authors： Baker PJ,DuFour L,Dixon M,Roopenian DC

更新日期：2000-06-01 00:00:00

abstract：:We developed an efficient electrotransformation system for the pathogenic fungus Histoplasma capsulatum and used it to examine the effects of features of the transforming DNA on transformation efficiency and fate of the transforming DNA and to demonstrate fungal expression of two recombinant Escherichia coli genes, hp...

journal_title：Infection and immunity

authors： Woods JP,Heinecke EL,Goldman WE

更新日期：1998-04-01 00:00:00

abstract：:The Yersinia high-pathogenicity island (HPI) is common to multiple virulence strategies used by Escherichia coli strains associated with urinary tract infection (UTI). Among the genes in this island are ybtP and ybtQ, encoding distinctive ATP binding cassette (ABC) proteins associated with iron(III)-yersiniabactin imp...

journal_title：Infection and immunity

authors： Koh EI,Hung CS,Henderson JP

更新日期：2016-04-22 00:00:00

abstract：:A monoclonal antibody (MAb) to Candida albicans (MAb B6.1) that protects against candidiasis and the nonprotective MAb B6 were compared for ability to support neutrophil (polymorphonuclear leukocyte [PMN]) candidacidal activity. Both MAbs are immunoglobulin M, and each recognizes distinct C. albicans mannan cell wall ...

journal_title：Infection and immunity

authors： Caesar-TonThat TC,Cutler JE

更新日期：1997-12-01 00:00:00

abstract：:BCG vaccines are a family of closely related daughter strains of an attenuated isolate of Mycobacterium bovis derived by in vitro passage from 1908 to 1921. During subsequent laboratory propagation of the vaccine strain until its lyophilization in 1961, BCG Pasteur underwent at least seven further genomic mutations. T...

journal_title：Infection and immunity

authors： Belley A,Alexander D,Di Pietrantonio T,Girard M,Jones J,Schurr E,Liu J,Sherman DR,Behr MA

更新日期：2004-05-01 00:00:00

abstract：:We have cloned and sequenced the d15 gene from two strains of Haemophilus influenzae type b (Hib) and two strains of nontypeable H. influenzae (NTHI). The nucleotide and deduced protein sequences of d15 are highly conserved, with only a small variable region identified near the carboxyl terminus of the protein. Analys...

journal_title：Infection and immunity

authors： Loosmore SM,Yang YP,Coleman DC,Shortreed JM,England DM,Klein MH

更新日期：1997-09-01 00:00:00

abstract：:Deciphering the mechanisms by which Borrelia burgdorferi controls the synthesis of proteins associated with mammalian infection will be an important step toward understanding the pathogenic properties of Lyme disease-causing bacteria. We present results of studies indicating that B. burgdorferi senses a wide variety o...

journal_title：Infection and immunity

authors： Babb K,El-Hage N,Miller JC,Carroll JA,Stevenson B

更新日期：2001-06-01 00:00:00

abstract：:The extracellular adherence protein (Eap) is a multifunctional Staphylococcus aureus protein and broad-spectrum adhesin for several host matrix and plasma proteins. We investigated the interactions of full-length Eap and five recombinant tandem repeat domains with host proteins by use of surface plasmon resonance (BIA...

journal_title：Infection and immunity

authors： Hussain M,Haggar A,Peters G,Chhatwal GS,Herrmann M,Flock JI,Sinha B

更新日期：2008-12-01 00:00:00

abstract：:It has been shown previously that serum from chronically infected patients with cystic fibrosis inhibits the phagocytosis of Pseudomonas aeruginosa by both normal and cystic fibrosis alveolar macrophages. In the present study, the ability of peripheral monocytes and polymorphonuclear leukocytes from normal volunteers ...

journal_title：Infection and immunity

authors： Thomassen MJ,Demko CA,Wood RE,Sherman JM

更新日期：1982-11-01 00:00:00

abstract：:Toll-like receptor (TLR)-based signaling pathways in the host may be modulated by pathogens during the course of infection. We describe a novel immunomodulatory mechanism in which Aspergillus fumigatus conidia induce attenuation of TLR2- and TLR4-mediated interleukin (IL)-6 and IL-1beta proinflammatory responses in hu...

journal_title：Infection and immunity

authors： Chai LY,Kullberg BJ,Vonk AG,Warris A,Cambi A,Latgé JP,Joosten LA,van der Meer JW,Netea MG

更新日期：2009-05-01 00:00:00

abstract：:Protection against infection with virulent blood (trypomastigote) forms of Trypanosoma cruzi was accomplished in mice by immunization with culture (mainly epimastigote) forms killed by treatment with sodium perchlorate. Sodium chloride, used instead of sodium perchlorate, with all other conditions kept the same, faile...

journal_title：Infection and immunity

authors： Kierszenbaum F,Budzko DB

更新日期：1975-09-01 00:00:00

abstract：:Fractionation of the culture medium showed that Streptococcus salivarius ATCC 25975 secreted a glucosyltransferase (Gtf) that was primer independent. On the basis of this observation, a gene library of S. salivarius chromosomal DNA cloned into lambda L47.1 was screened for a gene(s) coding for such an activity. As a r...

journal_title：Infection and immunity

authors： Simpson CL,Giffard PM,Jacques NA

更新日期：1995-02-01 00:00:00

abstract：:The Lyme disease spirochete, Borrelia burgdorferi, controls protein expression patterns during its tick-mammal infection cycle. Earlier studies demonstrated that B. burgdorferi synthesizes 4,5-dihydroxy-2,3-pentanedione (autoinducer-2 [AI-2]) and responds to AI-2 by measurably changing production of several infection-...

journal_title：Infection and immunity

authors： Arnold WK,Savage CR,Antonicello AD,Stevenson B

更新日期：2015-04-01 00:00:00

abstract：:Temperate bacteriophage can transfer toxin-encoding genes between bacteria, often resulting in acquired pathogenicity. However, little is known regarding the effects of the eukaryotic host on the phage-pathogen interaction. Using Streptococcus pyogenes as a model, we demonstrate, both in vitro and in vivo, that the eu...

journal_title：Infection and immunity

authors： Broudy TB,Fischetti VA

更新日期：2003-07-01 00:00:00

abstract：:PtlH is an essential component of the Ptl system, the type IV transporter responsible for secretion of pertussis toxin (PT) across the outer membrane of Bordetella pertussis. The nine Ptl proteins are believed to interact to form a membrane-spanning apparatus through which the toxin is secreted. In this study, we moni...

journal_title：Infection and immunity

authors： Verma A,Burns DL

更新日期：2007-05-01 00:00:00

abstract：:We investigated the cytokine/chemokine secretions and alteration of protein expression from peripheral blood mononuclear cells (PBMCs) cocultured with adult liver flukes (Opisthorchis viverrini) for 6 to 24 h. PBMC-derived proteins were identified by two-dimensional electrophoresis and mass spectrometry, and the cytok...

journal_title：Infection and immunity

authors： Hongsrichan N,Intuyod K,Pinlaor P,Khoontawad J,Yongvanit P,Wongkham C,Roytrakul S,Pinlaor S

更新日期：2014-05-01 00:00:00

abstract：:Ecto-5'-nucleotidase (CD73) is expressed abundantly on the apical surface of intestinal epithelial cells (IECs) and functions as the terminal enzyme in the generation of extracellular adenosine. Previous work demonstrated that adenosine signaling in IECs results in a number of tissue-protective effects during inflamma...

journal_title：Infection and immunity

authors： Kao DJ,Saeedi BJ,Kitzenberg D,Burney KM,Dobrinskikh E,Battista KD,Vázquez-Torres A,Colgan SP,Kominsky DJ

更新日期：2017-09-20 00:00:00

abstract：:The Escherichia coli genome varies in size from 4.5 to 5.5 Mb. It is unclear whether this variation may be distributed finely throughout the genome or is concentrated at just a few chromosomal loci or on plasmids. Further, the functional correlates of size variation in different genome copies are largely unexplored. W...

journal_title：Infection and immunity

authors： Rode CK,Melkerson-Watson LJ,Johnson AT,Bloch CA

更新日期：1999-01-01 00:00:00

abstract：:Free lipid A of Bordetella pertussis, Neisseria meningitidis, and Escherichia coli lipopolysaccharide (LPS) was prepared by hydrolysis in acetate buffer (pH 4.5); in addition, lipid A from B. pertussis and E. coli was prepared by hydrolysis in mineral acid (HCl). The precipitates obtained were purified by extraction m...

journal_title：Infection and immunity

authors： Caroff M,Cavaillon JM,Fitting C,Haeffner-Cavaillon N

更新日期：1986-11-01 00:00:00

abstract：:Significant resistance against influenza virus and Mycobacterium tuberculosis infections was induced when trehalose dimycolate from M. tuberculosis or M. bovis but not M. avium was combined with muramyl dipeptide. Trehalose dimycolate from M. tuberculosis, in contrast to that from M. avium, could confer resistance aga...

journal_title：Infection and immunity

authors： Masihi KN,Brehmer W,Lange W,Werner H,Ribi E

更新日期：1985-12-01 00:00:00

abstract：:A preparation procedure for scanning electron microscopy was developed by which gononcoccal colonies can be studied directly on the agar surface. After glutaraldehyde fixation directly in petri dishes, small agar pieces were cut out and dehydrated stepwise in increasing concentrations of ethanol. The blocks were there...

journal_title：Infection and immunity

authors： Elmros T,Hörstedt P,Winblad B

更新日期：1975-09-01 00:00:00

abstract：:To characterize the mechanism by which interleukin 10 (IL-10) inhibits Th1 responses to intracellular pathogens, we evaluated the interaction between IL-10 and Mycobacterium tuberculosis-induced gamma interferon (IFN-gamma) production by peripheral blood mononuclear cells from persons across the spectrum of tuberculou...

journal_title：Infection and immunity

authors： Gong JH,Zhang M,Modlin RL,Linsley PS,Iyer D,Lin Y,Barnes PF

更新日期：1996-03-01 00:00:00

abstract：:Development of hemolytic uremic syndrome (HUS) after infection by Shigella dysenteriae 1 or enterohemorrhagic Escherichia coli has been associated with the production of Shiga toxins (verotoxins). The putative target of Shiga toxins in HUS is the renal microvascular endothelium. This report shows that preincubation of...

journal_title：Infection and immunity

authors： Kaye SA,Louise CB,Boyd B,Lingwood CA,Obrig TG

更新日期：1993-09-01 00:00:00

abstract：:Recent studies have established the importance of neutrophils in innate resistance to Listeria monocytogenes infection in mice. The purpose of this study was to determine the importance of neutrophils in acquired resistance to L. monocytogenes infection. Previously immunized mice that were depleted of neutrophils by a...

journal_title：Infection and immunity

authors： Czuprynski CJ,Brown JF,Wagner RD,Steinberg H

更新日期：1994-11-01 00:00:00

abstract：:The interaction of the first component of complement with two serum-sensitive strains of Escherichia coli and Klebsiella pneumoniae was studied. It could be demonstrated that highly purified C1, free of immunoglobulin G and immunoglobulin M, binds to E. coli or K. pneumoniae. C1 binding was also found with specificall...

journal_title：Infection and immunity

authors： Loos M,Wellek B,Thesen R,Opferkuch W

更新日期：1978-10-01 00:00:00

abstract：:Naegleria fowleri produces fatal meningoencephalitis in humans and in experimentally infected laboratory animals. The course of the disease in mice is dependent upon the infecting dose of amoebae, route of inoculation, and prior exposure to Naegleria antigens. DUB/ICR mice were immunized by various routes and antigen ...

journal_title：Infection and immunity

authors： John DT,Weik RR,Adams AC

更新日期：1977-06-01 00:00:00

abstract：:The fucose-mannose ligand (FML) complex of Leishmania donovani is a promising vaccine candidate against murine and canine visceral leishmaniasis, and its main component is a 36-kDa nucleoside hydrolase (NH36). In this study, we tested the immune response and protection induced by the purified FML, the recombinant NH36...

journal_title：Infection and immunity

authors： Aguilar-Be I,da Silva Zardo R,Paraguai de Souza E,Borja-Cabrera GP,Rosado-Vallado M,Mut-Martin M,García-Miss Mdel R,Palatnik de Sousa CB,Dumonteil E

更新日期：2005-02-01 00:00:00

abstract：:In this analysis we have examined in detail the effects of low concentrations of zinc on the growth and dimorphism of Candida albicans. Evidence is presented that micromolar concentrations of zinc added to growth cultures grown at 25 degrees C (i) cause a twofold increase in the final concentration of spheres at satio...

journal_title：Infection and immunity

authors： Bedell GW,Soll DR

更新日期：1979-10-01 00:00:00

abstract：:We identified, by two-dimensional electrophoretic analysis and microsequencing, a protein of Chlamydia trachomatis elementary bodies which corresponds to the polypeptide (pgp3) encoded by open reading frame 3 (ORF3). Amino acid analysis showed that the first residue (Gly) found in the native protein is the one encoded...

journal_title：Infection and immunity

authors： Comanducci M,Manetti R,Bini L,Santucci A,Pallini V,Cevenini R,Sueur JM,Orfila J,Ratti G

更新日期：1994-12-01 00:00:00