A monoclonal antibody to Candida albicans enhances mouse neutrophil candidacidal activity.

abstract：:Previous work in our laboratory has shown that corticosterone increases the susceptibility of macrophages from Bcgs mice to the growth of Mycobacterium avium. The innate antimycobacterial activity of macrophages from Bcgr mice was not affected by corticosterone. In contrast to the differential effect of corticosterone...

journal_title：Infection and immunity

authors： Brown DH,LaFuse W,Zwilling BS

更新日期：1995-08-01 00:00:00

abstract：:Streptococcal protective antigen (Spa) is a newly described surface protein of group A streptococci that was recently shown to evoke protective antibodies (J. B. Dale, E. Y. Chiang, S. Liu, H. S. Courtney, and D. L. Hasty, J. Clin. Investig. 103:1261--1268, 1999). In this study, we have determined the complete sequenc...

journal_title：Infection and immunity

authors： McLellan DG,Chiang EY,Courtney HS,Hasty DL,Wei SC,Hu MC,Walls MA,Bloom JJ,Dale JB

更新日期：2001-05-01 00:00:00

abstract：:Glaesserella (Haemophilus) parasuis is a commensal bacterium of the upper respiratory tract in pigs and also the causative agent of Glässer's disease, which causes significant morbidity and mortality in pigs worldwide. Isolates are characterized into 15 serovars by their capsular polysaccharide, which has shown a corr...

journal_title：Infection and immunity

authors： Eberle KC,Hau SJ,Luan SL,Weinert LA,Stasko JA,Wang J,Peters SE,Langford PR,Rycroft AN,Wren BW,Maskell DJ,Tucker AW,Brockmeier SL

更新日期：2020-04-20 00:00:00

abstract：:Toll-like receptor (TLR) signal transduction is a central component of the innate immune response to pathogenic challenge. Although recent studies have begun to elucidate differences in acquired immunity in tissues of the human female reproductive tract, there is a relative paucity of work regarding innate defense mec...

journal_title：Infection and immunity

authors： Pioli PA,Amiel E,Schaefer TM,Connolly JE,Wira CR,Guyre PM

更新日期：2004-10-01 00:00:00

abstract：:The blood-stage development of malaria parasites is initiated by the invasion of merozoites into susceptible erythrocytes. Specific receptor-ligand interactions must occur for the merozoites to first attach to and then invade erythrocytes. Because the invasion process is essential for the parasite's survival and the m...

journal_title：Infection and immunity

authors： Tsuboi T,Kappe SH,al-Yaman F,Prickett MD,Alpers M,Adams JH

更新日期：1994-12-01 00:00:00

abstract：:The interaction between human neutrophils and wild-type Bordetella pertussis or mutants expressing altered lipopolysaccharide or lacking virulence factors-pertussis toxin, adenylate cyclase toxin, dermonecrotic toxin, filamentous hemagglutinin (FHA), pertactin, or BrkA-was examined. In the absence of antibodies, the w...

journal_title：Infection and immunity

authors： Weingart CL,Weiss AA

更新日期：2000-03-01 00:00:00

abstract：:To study the specific role of transmembrane tumor necrosis factor (tmTNF) in protective and pathological responses against the gastrointestinal helminth Trichinella spiralis, we compared the immune responses of TNF-alpha/lymphotoxin alpha (LTalpha)(-/-) mice expressing noncleavable transgenic tmTNF to those of TNF-alp...

journal_title：Infection and immunity

authors： Ierna MX,Scales HE,Mueller C,Lawrence CE

更新日期：2009-09-01 00:00:00

abstract：:Lipopolysaccharide (LPS) structure impacts the bactericidal action of cationic peptides, such as polymyxin B (PMB), and sensitivity to killing by normal human serum (NHS). Cultivation of different subspecies strains of Yersinia pestis isolated from unrelated geographic origins at various temperatures (mammals, 37 degr...

journal_title：Infection and immunity

authors： Anisimov AP,Dentovskaya SV,Titareva GM,Bakhteeva IV,Shaikhutdinova RZ,Balakhonov SV,Lindner B,Kocharova NA,Senchenkova SN,Holst O,Pier GB,Knirel YA

更新日期：2005-11-01 00:00:00

abstract：:Cytokine mRNA expression in biopsies of Mycobacterium ulcerans-infected human tissue was investigated using real-time PCR, and the findings were correlated with the clinical stages of disease and histopathologies. A broad range of cytokine mRNAs were detected in 16 early nodules and 28 late-stage ulcers, including tho...

journal_title：Infection and immunity

authors： Phillips R,Horsfield C,Mangan J,Laing K,Etuaful S,Awuah P,Nyarko K,Osei-Sarpong F,Butcher P,Lucas S,Wansbrough-Jones M

更新日期：2006-05-01 00:00:00

abstract：:Escherichia coli O157:H7 causes food and waterborne enteric infections that can result in hemorrhagic colitis and life-threatening hemolytic uremic syndrome. Intimate adherence of the bacteria to intestinal epithelial cells is mediated by intimin, but E. coli O157:H7 also possess several other putative adhesins, inclu...

journal_title：Infection and immunity

authors： Lloyd SJ,Ritchie JM,Rojas-Lopez M,Blumentritt CA,Popov VL,Greenwich JL,Waldor MK,Torres AG

更新日期：2012-03-01 00:00:00

abstract：:Toxic protein(s) neutralized with anti-C2 toxic serum was extracted from Clostridium botulinum type C spores treated with an alkaline mercaptoethanol solution. C2 toxicity in the spores was located in the spore coat fraction and was more heat stable than that found in culture fluid. ...

journal_title：Infection and immunity

authors： Yamakawa K,Nishida S,Nakamura S

更新日期：1983-08-01 00:00:00

abstract：:Exoenzyme S (ExoS), an ADP-ribosylating enzyme produced by the opportunistic pathogen Pseudomonas aeruginosa, is directly translocated into eukaryotic cells by bacterial contact. Within the cell, ExoS ADP-ribosylates the cell signaling protein Ras and causes inhibition of DNA synthesis and alterations in cytoskeletal ...

journal_title：Infection and immunity

authors： Olson JC,Fraylick JE,McGuffie EM,Dolan KM,Yahr TL,Frank DW,Vincent TS

更新日期：1999-06-01 00:00:00

abstract：:The Lyme disease spirochete, Borrelia burgdorferi, exists in a zoonotic cycle involving an arthropod tick and mammalian host. Dissemination of the organism within and between these hosts depends upon the spirochete's ability to traverse through complex tissues. Additionally, the spirochete outruns the host immune cell...

journal_title：Infection and immunity

authors： Sultan SZ,Manne A,Stewart PE,Bestor A,Rosa PA,Charon NW,Motaleb MA

更新日期：2013-06-01 00:00:00

abstract：:Factors which control the levels of catalase within yeast cells of Histoplasma capsulatum were studied. Only a small fraction of the total catalase activity could be detected in whole cells. The bulk of the activity was revealed in cell-free extracts or in cells permeabilized with acetone. The formation of the enzyme ...

journal_title：Infection and immunity

authors： Howard DH

更新日期：1983-03-01 00:00:00

abstract：:Mutation of retS (rtsM) of Pseudomonas aeruginosa strain PA103 reduces its virulence in both ocular and respiratory murine models of infection. In vitro, retS mutants exhibit loss of the ExsA-regulated type III secretion system (TTSS), reduced twitching motility, and a decrease in association with, invasion of, and su...

journal_title：Infection and immunity

authors： Zolfaghar I,Evans DJ,Ronaghi R,Fleiszig SM

更新日期：2006-07-01 00:00:00

abstract：:Various pathogenic bacteria with the capacity to live within eukaryotic cells activate an apoptotic program in infected host cells. Induction of apoptosis by Listeria monocytogenes in murine dendritic cells and hepatocytes has been described. Here we address the questions of whether and how the pathogen kills macropha...

journal_title：Infection and immunity

authors： Barsig J,Kaufmann SH

更新日期：1997-10-01 00:00:00

abstract：:The parameters of a persistent-state measles virus infection in BGM/MV cells were examined. The BGM/MV cell line was established by cocultivation of measles virus-infected primary C3H mouse brain cells with a stable line of African green monkey kidney cells (BGM). Initially, a morphologically mixed population of cells...

journal_title：Infection and immunity

authors： Menna JH,Collins AR,Flanagan TD

更新日期：1975-01-01 00:00:00

abstract：:The efficacy of the innate immune system depends on its ability to mount an appropriate response to diverse infections and damaging agents. Key components of this system are pattern recognition receptors that detect pathogen-associated and damage-associated molecular patterns (PAMPs and DAMPs). Nlrp1b is a pattern rec...

journal_title：Infection and immunity

authors： Liao KC,Mogridge J

更新日期：2013-02-01 00:00:00

abstract：:One mechanism by which interferons (IFNs) can inhibit chlamydial infection is by the induction of the enzyme indoleamine 2,3-dioxygenase (IDO), which restricts the availability of tryptophan, which is required for chlamydial growth. Other immunomodulating agents, including interleukin-1 (IL-1), can interact synergisti...

journal_title：Infection and immunity

authors： Carlin JM,Weller JB

更新日期：1995-05-01 00:00:00

abstract：:Immunization of New Zealand White rabbits with purified visna virus elicited antibody activity demonstrated by passive hemagglutination (PHA), complement fixation (CF), and indirect immunofluorescent tests. The antibody activities of hyperimmune sera and Sephadex G-200 fractions of the sera were studied. It was found ...

journal_title：Infection and immunity

authors： Karl SC,Thormar H

更新日期：1971-12-01 00:00:00

abstract：:We compared the immune defense of mice with chronic granulomatous disease (CGD mice) with that of wild-type C57BL/6 mice for their response to Sporothrix schenckii. A subcutaneous injection of 5 x 10(4) CFU S. schenckii strain IFM41598 into CGD mice resulted in systemic infection and death within 84 days. In contrast,...

journal_title：Infection and immunity

authors： Kajiwara H,Saito M,Ohga S,Uenotsuchi T,Yoshida S

更新日期：2004-09-01 00:00:00

abstract：:The mechanism(s) of interaction between Mycoplasma pulmonis and eucaryotic cells was studied by adherence to and hemagglutination of erythrocytes. Simple and complex carbohydrates and glycoproteins were unable to inhibit either adherence or hemagglutination, indicating that neither was a lectin activity. Both interact...

journal_title：Infection and immunity

authors： Minion FC,Cassell GH,Pnini S,Kahane I

更新日期：1984-05-01 00:00:00

abstract：:Monolayer cultures of LLC-MK2 rhesus monkey kidney cells become persistently infected with simian virus 40 after infection at input multiplicities of 100, 10, or 1 plaque-forming unit per cell. After 3 weeks, all cells of the cultures infected at a multiplicity of 1 plaque-forming unit per cell produced the simian vir...

journal_title：Infection and immunity

authors： Norkin LC

更新日期：1977-12-01 00:00:00

abstract：:The appearance of lymphotoxin in the culture fluid of phytohemagglutinin (PHA)-stimulated mouse spleen cells required two cell fractions that were separated by adherence to plastic. Upon stimulation with PHA, neither cell fraction alone produced significant amounts of lymphotoxin; however, when the cell fractions were...

journal_title：Infection and immunity

authors： Aksamit RR,Leonard EJ

更新日期：1982-06-01 00:00:00

abstract：:Murine monoclonal and rabbit, murine, and human polyclonal antibodies against chlamydial lipopolysaccharide (LPS) were characterized by the passive hemolysis and passive hemolysis inhibition assays and by absorption experiments with LPSs of Chlamydia psittaci, Chlamydia trachomatis, and a recombinant strain of Salmone...

journal_title：Infection and immunity

authors： Brade L,Holst O,Kosma P,Zhang YX,Paulsen H,Krausse R,Brade H

更新日期：1990-01-01 00:00:00

abstract：:Here we describe a protocol for purifying Borrelia burgdorferi from feeding ticks by velocity centrifugation and Percoll density gradient centrifugation. The purified spirochetes were motile and 10- to 20-fold purer than the bacteria in crude tick homogenates. The purified bacteria were present in sufficient quantity ...

journal_title：Infection and immunity

authors： Rathinavelu S,de Silva AM

更新日期：2001-06-01 00:00:00

abstract：:Previous work (P. Castric, F. J. Cassels, and R. W. Carlson, J. Biol. Chem. 276:26479-26485, 2001) has shown the Pseudomonas aeruginosa 1244 pilin glycan to be covalently bound to a serine residue. N-terminal sequencing of pilin fragments produced from endopeptidase treatment and identified by reaction with a glycan-s...

journal_title：Infection and immunity

authors： Comer JE,Marshall MA,Blanch VJ,Deal CD,Castric P

更新日期：2002-06-01 00:00:00

abstract：:The protozoan parasite Giardia duodenalis (Giardia lamblia) is one of the most commonly found intestinal pathogens in mammals, including humans. In the current study, a Giardia muris-mouse model was used to analyze cytokine transcription patterns and histological changes in intestinal tissue at different time points d...

journal_title：Infection and immunity

authors： Dreesen L,De Bosscher K,Grit G,Staels B,Lubberts E,Bauge E,Geldhof P

更新日期：2014-08-01 00:00:00

abstract：:The immunostimulation provided by the mycobacterial cell wall has been exploited for many decades, e.g., in Freund's complete adjuvant. Recently, the underlying mechanism behind this adjuvant activity, including Toll receptor signaling, has begun to be unraveled, confirming the potential of mycobacterial constituents ...

journal_title：Infection and immunity

authors： Rosenkrands I,Agger EM,Olsen AW,Korsholm KS,Andersen CS,Jensen KT,Andersen P

更新日期：2005-09-01 00:00:00

abstract：:The Yersinia high-pathogenicity island (HPI) is common to multiple virulence strategies used by Escherichia coli strains associated with urinary tract infection (UTI). Among the genes in this island are ybtP and ybtQ, encoding distinctive ATP binding cassette (ABC) proteins associated with iron(III)-yersiniabactin imp...

journal_title：Infection and immunity

authors： Koh EI,Hung CS,Henderson JP

更新日期：2016-04-22 00:00:00