Characterization of murine monoclonal and murine, rabbit, and human polyclonal antibodies against chlamydial lipopolysaccharide.

abstract：:Relapsing fever is a rapidly progressive and severe septic disease caused by certain Borrelia spirochetes. The disease is divided into two forms, i.e., epidemic relapsing fever, caused by Borrelia recurrentis and transmitted by lice, and the endemic form, caused by several Borrelia species, such as B. duttonii, and tr...

journal_title：Infection and immunity

authors： Meri T,Cutler SJ,Blom AM,Meri S,Jokiranta TS

更新日期：2006-07-01 00:00:00

abstract：:Salmonellae possess the ability to adhere to and invade macrophages and in so doing trigger a number of intracellular events that are associated with cellular activation. As an initial approach to defining the mechanisms by which invasive salmonellae alter macrophage function, we have explored the impact of Salmonella...

journal_title：Infection and immunity

authors： Mizel SB,Kucera LS,Richardson SH,Ciacci F,Iyer NP

更新日期：1995-05-01 00:00:00

abstract：:Rabbits immunized with group B type III, group C, and Streptococcus pneumoniae type XIV streptococcal vaccines developed autoantibodies reactive with autologous and isologous erythrocytes and human O-positive erythrocytes at reduced temperatures. The cold agglutinin antibodies were present in both the immunoglobulin M...

journal_title：Infection and immunity

authors： Colling RG,Pearson TC,Brown JC

更新日期：1983-07-01 00:00:00

abstract：:Helicobacter pylori colonizes the gastric epithelium of at least 50% of the world's human population, playing a causative role in the development of chronic gastritis, peptic ulcers, and gastric adenocarcinoma. Current evidence indicates that H. pylori can invade epithelial cells in the gastric mucosa. However, relati...

journal_title：Infection and immunity

authors： Terebiznik MR,Vazquez CL,Torbicki K,Banks D,Wang T,Hong W,Blanke SR,Colombo MI,Jones NL

更新日期：2006-12-01 00:00:00

abstract：:Since the pH of the gingival crevice increases from below neutrality in health to above pH 8 in disease, we decided to investigate the effect of environmental pH on the growth and enzyme activity of Bacteroides gingivalis W50. Cells were grown in a chemostat under hemin-excess conditions over a range of pH values; sta...

journal_title：Infection and immunity

authors： McDermid AS,McKee AS,Marsh PD

更新日期：1988-05-01 00:00:00

abstract：:The Th-2 response to microfilariae of Brugia malayi in BALB/c mice is associated with peritoneal eosinophilia. These eosinophils had an activated hypodense phenotype in vivo and expressed high levels of the class II major histocompatibility complex (MHC). Interleukin 4 up-regulated the class II MHC, whereas gamma inte...

journal_title：Infection and immunity

authors： Mawhorter SD,Pearlman E,Kazura JW,Boom WH

更新日期：1993-12-01 00:00:00

abstract：:Deciphering the mechanisms by which Borrelia burgdorferi controls the synthesis of proteins associated with mammalian infection will be an important step toward understanding the pathogenic properties of Lyme disease-causing bacteria. We present results of studies indicating that B. burgdorferi senses a wide variety o...

journal_title：Infection and immunity

authors： Babb K,El-Hage N,Miller JC,Carroll JA,Stevenson B

更新日期：2001-06-01 00:00:00

abstract：:The outer membrane (OM) of Gram-negative bacteria is an asymmetric lipid bilayer that consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS). The asymmetric character and unique biochemistry of LPS molecules contribute to the OM's ability to function as a molecular permeability barrier tha...

journal_title：Infection and immunity

authors： Giordano NP,Cian MB,Dalebroux ZD

更新日期：2020-06-22 00:00:00

abstract：:The protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide (CP5) was examined in a modified model of catheter-induced endocarditis. Rats were catheterized by surgically passing a polyethylene catheter through the right carotid artery and aortic valve into the left ventricle. The ...

journal_title：Infection and immunity

authors： Lee JC,Park JS,Shepherd SE,Carey V,Fattom A

更新日期：1997-10-01 00:00:00

abstract：:Ureaplasma urealyticum is a common commensal of the female lower urogenital tract, yet it has been shown to be an important cause of chorioamnion infection, respiratory and central nervous system disease, and death in premature infants. It has been suggested that only certain serovars are capable of producing invasive...

journal_title：Infection and immunity

authors： Zheng X,Teng LJ,Watson HL,Glass JI,Blanchard A,Cassell GH

更新日期：1995-03-01 00:00:00

abstract：:Surface proteins in gram-positive bacteria are frequently required for virulence, and many are attached to the cell wall by sortase enzymes. Bacteria frequently encode more than one sortase enzyme and an even larger number of potential sortase substrates that possess an LPXTG-type cell wall sorting signal. In order to...

journal_title：Infection and immunity

authors： Comfort D,Clubb RT

更新日期：2004-05-01 00:00:00

abstract：:The obligate intracellular parasite Toxoplasma gondii can actively infect any nucleated cell type, including cells from the immune system. The rapid transfer of T. gondii from infected dendritic cells to effector natural killer (NK) cells may contribute to the parasite's sequestration and shielding from immune recogni...

journal_title：Infection and immunity

authors： Sultana MA,Du A,Carow B,Angbjär CM,Weidner JM,Kanatani S,Fuks JM,Muliaditan T,James J,Mansfield IO,Campbell TM,Liu L,Kadri N,Lambert H,Barragan A,Chambers BJ

更新日期：2017-09-20 00:00:00

abstract：:After lysing the phagocytic vacuole, Shigella spp. accumulate filaments of polymerized actin on their surface at one pole, leading to the formation of actin tails that enable them to move through the cytoplasm. We have recently demonstrated that the Shigella protein IcsA is located at the pole that is adjacent to the ...

journal_title：Infection and immunity

authors： Goldberg MB,Theriot JA,Sansonetti PJ

更新日期：1994-12-01 00:00:00

abstract：:Survival of macrophage microbicidal activity is a prerequisite for invasive disease caused by the enteric pathogen Salmonella enterica serovar Typhimurium. Flavohemoglobins, such as those of Escherichia coli, Salmonella, and yeast, play vital roles in protection of these microorganisms in vitro from nitric oxide (NO) ...

journal_title：Infection and immunity

authors： Stevanin TM,Poole RK,Demoncheaux EA,Read RC

更新日期：2002-08-01 00:00:00

abstract：:To assess the relationship between the within-host diversity of malaria infections and the susceptibility of the host to subsequent infection, we genotyped 60 children's successive infections from birth through 3 years of life. MSP-1 Block2 genotypes were used to estimate the complexity of infection (COI). Malaria tra...

journal_title：Infection and immunity

authors： Branch OH,Takala S,Kariuki S,Nahlen BL,Kolczak M,Hawley W,Lal AA

更新日期：2001-12-01 00:00:00

abstract：:Tubercle bacilli failed to grow in iron-void media enriched with solutions of iron-containing transferrin (Tr) or ferritin (F) because these substances do not provide the bacilli with iron, which is essential for their growth. Animal serum and macrophages possessed no iron carrier with an ability to satisfy the need o...

journal_title：Infection and immunity

authors： Golden CA,Kochan I,Spriggs DR

更新日期：1974-01-01 00:00:00

abstract：:Growth in colonies with type 1 morphology and the presence of pili are characteristics that have been associated with virulence of gonococci for humans. To determine whether the presence of pili per se might be responsible for colony type 1 morphology, the relationship of pili to colony type was examined in various sp...

journal_title：Infection and immunity

authors： McGee ZA,Dourmashkin RR,Gross JG,Clark JB,Taylor-Robinson D

更新日期：1977-02-01 00:00:00

abstract：:We demonstrate that 2-month-old female B10.T(6R) mice are highly resistant to systemic infection with the KIM5 strain of Yersinia pestis and that B10.T(6R) mice become susceptible to Y. pestis infection by the age of 5 months. In this study, young (2-month-old) and middle-aged (5- to 12-month-old) B10.T(6R) mice were ...

journal_title：Infection and immunity

authors： Lambert ND,Langfitt DM,Nilles ML,Bradley DS

更新日期：2011-11-01 00:00:00

abstract：:One of the first steps in the development of cerebral toxoplasmosis is the penetration of the blood-brain barrier, which is comprised of microvascular endothelial cells. We examined the capacity of human brain microvascular endothelial cells (HBMEC) to interact with Toxoplasma gondii. We found that stimulation of HBME...

journal_title：Infection and immunity

authors： Däubener W,Spors B,Hucke C,Adam R,Stins M,Kim KS,Schroten H

更新日期：2001-10-01 00:00:00

abstract：:The receptor specificities of four Escherichia coli cloned hemagglutinins, AFA-I, AFA-III, F1845 fimbriae, and the Dr hemagglutinin were studied. Evidence is provided that all four hemagglutinins recognize as their receptor the Dr blood group antigen. However, results of experiments using enzyme-treated erythrocytes a...

journal_title：Infection and immunity

authors： Nowicki B,Labigne A,Moseley S,Hull R,Hull S,Moulds J

更新日期：1990-01-01 00:00:00

abstract：:Establishment and maintenance of chronic lung infections with mucoid Pseudomonas aeruginosa in patients with cystic fibrosis (CF) require that the bacteria avoid host defenses. Elaboration of the extracellular, O-acetylated mucoid exopolysaccharide, or alginate, is a major microbial factor in resistance to immune effe...

journal_title：Infection and immunity

authors： Pier GB,Coleman F,Grout M,Franklin M,Ohman DE

更新日期：2001-03-01 00:00:00

abstract：:Plasmid DNA from two strains of enterotoxigenic Escherichia coli harboring genes encoding coli surface antigen 4 (CS4) and from seven Indian enterotoxigenic E. coli isolates cross-hybridized at low stringency but not at high stringency with two polynucleotide probes derived from the colonization factor antigen I (CFA/...

journal_title：Infection and immunity

authors： Sommerfelt H,Grewal HM,Svennerholm AM,Gaastra W,Flood PR,Viboud G,Bhan MK

更新日期：1992-09-01 00:00:00

abstract：:The complement system plays an important role in the host defense against infection, and the formation of the terminal complement complex on the bacterial surface has been shown to be particularly important in killing of gram-negative bacteria. The gram-negative periodontal pathogen Porphyromonas gingivalis is resista...

journal_title：Infection and immunity

authors： Slaney JM,Gallagher A,Aduse-Opoku J,Pell K,Curtis MA

更新日期：2006-09-01 00:00:00

abstract：:Strains of type III group B streptococci isolated from patients with neonatal sepsis are generally resistant to complement-mediated phagocytic killing in the absence of specific antibody. It has been suggested that the resistance of type III group B streptococci to phagocytosis results from inhibition of alternative-c...

journal_title：Infection and immunity

authors： Marques MB,Kasper DL,Pangburn MK,Wessels MR

更新日期：1992-10-01 00:00:00

abstract：:Campylobacter jejuni is the leading cause of infectious gastroenteritis in industrialized nations. Its ability to enter and survive within nonphagocytic cells is thought to be very important for pathogenesis. However, little is known about the C. jejuni determinants that mediate these processes. Through an extensive t...

journal_title：Infection and immunity

authors： Novik V,Hofreuter D,Galán JE

更新日期：2010-08-01 00:00:00

abstract：:The viaB locus coding for the Vi antigen of Salmonella typhi Ty2 was cloned on a 40.6-kilobase fragment into the cosmid vector pHC79. The live, oral, attenuated Vi-negative S. typhi Ty21a vaccine strain was transformed with the recombinant cosmid encoding the viaB locus. Homologous recombination of the viaB locus into...

journal_title：Infection and immunity

authors： Cryz SJ Jr,Fürer E,Baron LS,Noon KF,Rubin FA,Kopecko DJ

更新日期：1989-12-01 00:00:00

abstract：:The cell surface hydrophobicity of 10 pigmented and 4 nonpigmented clinical Serratia marcescens strains was studied, based on the ability of the strains to adhere to hydrocarbons and to polystyrene. The cell surface hydrophobicity depended greatly on growth temperature; all of the strains tested were adherent followin...

journal_title：Infection and immunity

authors： Rosenberg M,Blumberger Y,Judes H,Bar-Ness R,Rubinstein E,Mazor Y

更新日期：1986-03-01 00:00:00

abstract：:Mice (BALB/cJ, C3H/HeN, and C3H/HeJ) primed with actinomycin D became highly susceptible to lethal intoxication with staphylococcal enterotoxin B (SEB). The mice underwent toxicosis and toxic shock and died. Actinomycin D-primed C3H/HeN and C3H/HeJ mice showed equal sensitivity to SEB, suggesting that bacterial lipopo...

journal_title：Infection and immunity

authors： Chen JY,Qiao Y,Komisar JL,Baze WB,Hsu IC,Tseng J

更新日期：1994-10-01 00:00:00

abstract：:Previous reports have demonstrated that heat-stable (A-type) capsule on piliated enterotoxigenic Escherichia coli enhances colonization of enterotoxigenic E. coli in the small intestine and enhances virulence of enterotoxigenic E. coli. In this report, four encapsulated enterotoxigenic E. coli strains and one encapsul...

journal_title：Infection and immunity

authors： Runnels PL,Moon HW

更新日期：1984-09-01 00:00:00

abstract：:Previous studies demonstrated that Mycoplasma arthritidis strain 158 acquired a high degree of virulence upon lysogenization with bacteriophage MAV1. In the present study, the association between MAV1 and virulence was reexamined by creating new lysogens of 158 and of a relatively avirulent mutant, strain 158-1. In th...

journal_title：Infection and immunity

authors： Clapper B,Tu AH,Simmons WL,Dybvig K

更新日期：2004-12-01 00:00:00