Motility is crucial for the infectious life cycle of Borrelia burgdorferi.

abstract：:A receptor moiety and blood group substance recognized by the O75X adhesin was studied. Well-defined erythrocytes representing different blood group systems and bacterial derivatives carrying plasmid pBJN406 encoding the adhesin were used in a direct hemagglutination assay. We showed that Dr blood group antigen, a com...

journal_title：Infection and immunity

authors： Nowicki B,Moulds J,Hull R,Hull S

更新日期：1988-05-01 00:00:00

abstract：:Adherence of blastoconidia to epidermal corneocytes is an early event in Candida colonization and infection of the skin. Pathogenic species adhere more avidly than nonpathogenic species, transform to hyphal growth, and invade the stratum corneum of the skin. Adherence was studied by scanning electron microscopy of exp...

journal_title：Infection and immunity

authors： Ray TL,Payne CD

更新日期：1988-08-01 00:00:00

abstract：:Cryptococcal meningoencephalitis develops as a result of hematogenous dissemination of inhaled Cryptococcus neoformans from the lung to the brain. The mechanism(s) by which C. neoformans crosses the blood-brain barrier (BBB) is a key unresolved issue in cryptococcosis. We used both an in vivo mouse model and an in vit...

journal_title：Infection and immunity

authors： Chang YC,Stins MF,McCaffery MJ,Miller GF,Pare DR,Dam T,Paul-Satyaseela M,Kim KS,Kwon-Chung KJ

更新日期：2004-09-01 00:00:00

abstract：:The objective of this study was to identify disease-related changes in lymphocyte populations within ileal mucosae of calves with cryptosporidiosis. Groups of five neonatal calves were orally infected at 3 days of age with 10(8) oocysts and maintained in enteric-pathogen-free conditions until clinical disease was esta...

journal_title：Infection and immunity

authors： Wyatt CR,Brackett EJ,Perryman LE,Rice-Ficht AC,Brown WC,O'Rourke KI

更新日期：1997-01-01 00:00:00

abstract：:Fimbriae, lipopolysaccharide (LPS), and extracellular polymeric substance (EPS) all contribute to biofilm formation by the periodontopathogen Aggregatibacter actinomycetemcomitans. To understand how individual biofilm determinants respond to changing environmental conditions, the transcription of genes responsible for...

journal_title：Infection and immunity

authors： Amarasinghe JJ,Scannapieco FA,Haase EM

更新日期：2009-07-01 00:00:00

abstract：:Individuals in areas of Plasmodium falciparum endemicity develop immunity to malaria after repeated exposure. Knowledge of the acquisition and nature of protective immune responses to P. falciparum is presently limited, particularly for young children. We examined antibodies (IgM, IgG, and IgG subclasses) to merozoite...

journal_title：Infection and immunity

authors： Stanisic DI,Fowkes FJ,Koinari M,Javati S,Lin E,Kiniboro B,Richards JS,Robinson LJ,Schofield L,Kazura JW,King CL,Zimmerman P,Felger I,Siba PM,Mueller I,Beeson JG

更新日期：2015-02-01 00:00:00

abstract：:Uropathogenic Escherichia coli (UPEC) is the leading cause of urinary tract infections. These bacteria undertake a multistage infection cycle involving invasion of and proliferation within urinary tract epithelial cells, leading to the rupture of the host cell and dispersal of the bacteria, some of which have a highly...

journal_title：Infection and immunity

authors： Iosifidis G,Duggin IG

更新日期：2020-08-19 00:00:00

abstract：:The bacterial pathogen Listeria monocytogenes causes foodborne systemic disease in pregnant women, which can lead to preterm labor, stillbirth, or severe neonatal disease. Colonization of the maternal decidua appears to be an initial step in the maternal component of the disease as well as bacterial transmission to th...

journal_title：Infection and immunity

authors： Rizzuto G,Tagliani E,Manandhar P,Erlebacher A,Bakardjiev AI

更新日期：2017-07-19 00:00:00

abstract：:The gene expression and cytokine release of the proinflammatory cytokines interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor alpha (TNF-alpha) after infection of human epithelial cells (HEp-2 cells) and polymorphonuclear granulocytes (PMNs) were investigated by using isogenic pairs of Listeria monocytogen...

journal_title：Infection and immunity

authors： Arnold R,Scheffer J,König B,König W

更新日期：1993-06-01 00:00:00

abstract：:Classical and El Tor strains of Vibrio cholerae were examined for production of bacteriophage or bacteriophage-related material by electron microscopy of mitomycin C-induced cultures. The strains were also tested for pathogenicity by using the ligated ileal loops of adult rabbits. Of the 27 strains tested, 25 showed a...

journal_title：Infection and immunity

authors： Parker C,Richardson SH,Romig WR

更新日期：1970-04-01 00:00:00

abstract：:Since melanin is considered a virulence factor in Cryptococcus neoformans, its suppression at 37 degrees C has been perplexing. We now show an opposite thermal regulation of superoxide dismutase (SOD), consistent with a compensatory mechanism. Moreover, we demonstrate normal SOD and catalase levels in albino, oxygen-s...

journal_title：Infection and immunity

authors： Jacobson ES,Jenkins ND,Todd JM

更新日期：1994-09-01 00:00:00

abstract：:Photobacterium damselae subsp. damselae causes infections and fatal disease in marine animals and in humans. Highly hemolytic strains produce damselysin (Dly) and plasmid-encoded HlyA (HlyA(pl)). These hemolysins are encoded by plasmid pPHDD1 and contribute to hemolysis and virulence for fish and mice. In this study, ...

journal_title：Infection and immunity

authors： Rivas AJ,Balado M,Lemos ML,Osorio CR

更新日期：2013-09-01 00:00:00

abstract：:Understanding the extent to which genetic factors influence the immune response is important in the development of subunit vaccines. Associations with HLA gene polymorphisms appear insufficient to explain the range of variation in immune responses to vaccines and to infections by major pathogens. In this study of Gamb...

journal_title：Infection and immunity

authors： Jepson A,Banya W,Sisay-Joof F,Hassan-King M,Nunes C,Bennett S,Whittle H

更新日期：1997-03-01 00:00:00

abstract：:Hookworm glutathione S-transferases (GSTs) are critical for parasite blood feeding and survival and represent potential targets for vaccination. Three cDNAs, each encoding a full-length GST protein from the human hookworm Necator americanus (and designated Na-GST-1, Na-GST-2, and Na-GST-3, respectively) were isolated ...

journal_title：Infection and immunity

authors： Zhan B,Perally S,Brophy PM,Xue J,Goud G,Liu S,Deumic V,de Oliveira LM,Bethony J,Bottazzi ME,Jiang D,Gillespie P,Xiao SH,Gupta R,Loukas A,Ranjit N,Lustigman S,Oksov Y,Hotez P

更新日期：2010-04-01 00:00:00

abstract：:Cigarette smoke exposure increases the risk of pulmonary and invasive infections caused by Streptococcus pneumoniae, the most commonly isolated organism from patients with community-acquired pneumonia. Despite this association, the mechanisms by which cigarette smoke exposure diminishes host defense against S. pneumon...

journal_title：Infection and immunity

authors： Phipps JC,Aronoff DM,Curtis JL,Goel D,O'Brien E,Mancuso P

更新日期：2010-03-01 00:00:00

abstract：:Normal cell polarity protects epithelial cells against Pseudomonas aeruginosa invasion and cytotoxicity. Using epithelial cell clones with selective defects in sorting of membrane constituents, and using hepatocyte growth factor pretreatment, we found that polarized susceptibility to P. aeruginosa can be altered witho...

journal_title：Infection and immunity

authors： Fleiszig SM,Vallas V,Jun CH,Mok L,Balkovetz DF,Roth MG,Mostov KE

更新日期：1998-07-01 00:00:00

abstract：:Proliferation of Bordetella pertussis in the lungs of infant mice challenged by the intranasal route was examined. The bacteria rapidly proliferated in the lungs of mice challenged with a sublethal dose of a wild-type strain (BP338) or a filamentous hemagglutinin mutant (BPM409) from 500 at day 0 to 10(7) at day 15. T...

journal_title：Infection and immunity

authors： Goodwin MS,Weiss AA

更新日期：1990-10-01 00:00:00

abstract：:In experiments described herein, it was observed that guinea pigs with delayed-type hypersensitivity to tuberculoproteins under various experimental conditions, with or without passive transfer of serum from immune donors, manifested no acquired immunity against aerogenically induced tuberculosis. These results are di...

journal_title：Infection and immunity

authors： Reggiardo Z,Middlebrook G

更新日期：1974-05-01 00:00:00

abstract：:Trypanosoma musculi produces a chronic infection with a consistently elevated parasitemia in nude mice. Thymic reconstitution of nude mice restores immunity to the infection. ...

journal_title：Infection and immunity

authors： Rank RG,Roberts DW,Weidanz WP

更新日期：1977-05-01 00:00:00

abstract：:Vibrio parahaemolyticus is a leading cause of seafood-borne gastroenteritis; however, its virulence mechanisms are not well understood. The identification of type III secreted proteins has provided candidate virulence factors whose functions are still being elucidated. Genotypic strain variability contributes a level ...

journal_title：Infection and immunity

authors： Casselli T,Lynch T,Southward CM,Jones BW,DeVinney R

更新日期：2008-05-01 00:00:00

abstract：:We identified and characterized a gene encoding a homologue of the B subunits of cholera toxin (CTB) and heat-labile enterotoxin (LTB) of Escherichia coli from a clinical isolate of Citrobacter freundii that was found to produce a factor in the culture supernatant that cross-reacted with antibodies to CTB and LTB when...

journal_title：Infection and immunity

authors： Karasawa T,Ito H,Tsukamoto T,Yamasaki S,Kurazono H,Faruque SM,Nair GB,Nishibuchi M,Takeda Y

更新日期：2002-12-01 00:00:00

abstract：:Gamma interferon (IFN-gamma) is produced in response to circulating lipopolysaccharide (LPS) and contributes to the lethality of endotoxic shock. To address the cellular source of IFN-gamma production in vivo, T cells and B cells were magnetically purified from C57BL/6 mouse spleens 5 h following endotoxin injection. ...

journal_title：Infection and immunity

authors： Heinzel FP,Rerko RM,Ling P,Hakimi J,Schoenhaut DS

更新日期：1994-10-01 00:00:00

abstract：:The influence of D-alanine and carbohydrate substitution of lipoteichoic acids (LTAs) on the binding of antibody directed to the polyglycerol phosphate (PGP) portion was found to be at least partially dependent upon the mode of presentation of the antigen. There were greater differences in binding of anti-PGP immunogl...

journal_title：Infection and immunity

authors： Kessler RE,Thivierge BH

更新日期：1983-08-01 00:00:00

abstract：:The gene encoding the 35-kDa immunogenic Treponema pallidium subsp. pallidum (T. pallidum) membrane protein C, TmpC, was cloned, sequenced, and expressed in Escherichia coli. The deduced amino acid sequence carries on N-terminal signal sequence with a four-amino-acid motif, which is characteristic for bacterial lipopr...

journal_title：Infection and immunity

authors： Schouls LM,van der Heide HG,van Embden JD

更新日期：1991-10-01 00:00:00

abstract：:Escherichia coli 83972 is a clinical asymptomatia bacteriuric isolate that is able to colonize the human urinary bladder without inducing an immune response. Here we demonstrate that one of the mechanisms by which this strain has become attenuated is through the mutation of its genes encoding type 1 and P fimbriae. ...

journal_title：Infection and immunity

authors： Klemm P,Roos V,Ulett GC,Svanborg C,Schembri MA

更新日期：2006-01-01 00:00:00

abstract：:We utilized magnetic resonance imaging to visualize lesions in the lungs of guinea pigs infected by low-dose aerosol exposure to Mycobacterium tuberculosis. Lesions were prominent in such images, and colorized three-dimensional reconstructions of images revealed a very uniform distribution in the lungs. Lesion numbers...

journal_title：Infection and immunity

authors： Kraft SL,Dailey D,Kovach M,Stasiak KL,Bennett J,McFarland CT,McMurray DN,Izzo AA,Orme IM,Basaraba RJ

更新日期：2004-10-01 00:00:00

abstract：:Anti-CD4 antibodies, which cause CD4(+) T-cell depletion, have been shown to increase susceptibility to infections in mice. Thus, development of anti-CD4 antibodies for clinical use raises potential concerns about suppression of host defense mechanisms against pathogens and tumors. The anti-human CD4 antibody kelixima...

journal_title：Infection and immunity

authors： Herzyk DJ,Gore ER,Polsky R,Nadwodny KL,Maier CC,Liu S,Hart TK,Harmsen AG,Bugelski PJ

更新日期：2001-02-01 00:00:00

abstract：:Inoculation of neonatal CD-1 mice by multiple routes with an amyocarditic temperature-sensitive (ts) mutant (ts 1) derived from a myocarditic parent variant of coxsackievirus B3 (CVB3(m)) resulted in approximately half of the neonates surviving to adolescence. Challenge of the ts 1 survivors with CVB3(m) did not induc...

journal_title：Infection and immunity

authors： Gauntt CJ,Paque RE,Trousdale MD,Gudvangen RJ,Barr DT,Lipotich GJ,Nealon TJ,Duffey PS

更新日期：1983-02-01 00:00:00

abstract：:Each of the serotypes of Haemophilus influenzae (types a to f) may colonize the respiratory tract of humans, but only type b strains commonly cause invasive systemic infections. To investigate the role of complement in immunity to encapsulated non-type b strains, rats were depleted of C3 with cobra venom factor and ch...

journal_title：Infection and immunity

authors： Corrall CJ,Winkelstein JA,Moxon ER

更新日期：1982-03-01 00:00:00

abstract：:Two murine monoclonal antibodies (immunoglobulin M) evoked against human kidney tissue were examined for cross-reactivity with group A streptococci. A glomerulus-specific antibody, PMII.40.H.2, cross-reacted in an enzyme-linked immunosorbent assay with purified pepsin-extracted M proteins from type 6 and 12 streptococ...

journal_title：Infection and immunity

authors： Goroncy-Bermes P,Dale JB,Beachey EH,Opferkuch W

更新日期：1987-10-01 00:00:00