Studies on the catalase of Histoplasma capsulatum.

abstract：:Helicobacter pylori colonizes the gastric epithelium of at least 50% of the world's human population, playing a causative role in the development of chronic gastritis, peptic ulcers, and gastric adenocarcinoma. Current evidence indicates that H. pylori can invade epithelial cells in the gastric mucosa. However, relati...

journal_title：Infection and immunity

authors： Terebiznik MR,Vazquez CL,Torbicki K,Banks D,Wang T,Hong W,Blanke SR,Colombo MI,Jones NL

更新日期：2006-12-01 00:00:00

abstract：:The heparin-binding hemagglutinin (HBHA) of Mycobacterium tuberculosis is a surface-expressed adhesin that can affect binding to host cells via a unique, methylated, carboxyl-terminal, lysine-, alanine-, and proline-rich repeat region. It has been implicated in extrapulmonary dissemination of M. tuberculosis from the ...

journal_title：Infection and immunity

authors： Parra M,Pickett T,Delogu G,Dheenadhayalan V,Debrie AS,Locht C,Brennan MJ

更新日期：2004-12-01 00:00:00

abstract：:The recombinant protective antigen (rPA) of Bacillus anthracis is a promising anthrax vaccine. We compared serum immunoglobulin G levels and toxin-neutralizing antibody titers in rabbits following delivery of various doses of vaccine by microneedle-based intradermal (i.d.) delivery or intramuscular (i.m.) injection us...

journal_title：Infection and immunity

authors： Mikszta JA,Dekker JP 3rd,Harvey NG,Dean CH,Brittingham JM,Huang J,Sullivan VJ,Dyas B,Roy CJ,Ulrich RG

更新日期：2006-12-01 00:00:00

abstract：:Raising the magnesium level from 0.4 to 1.5 mM in a medium containing only amino acids (2.08%), salts, and vitamins increased enterotoxin B production by Staphylococcus aureus S-6 by about 80%. The level of phosphates in the medium was lowered to one-tenth (to 2.87 mM) the original amount without adversely affecting g...

journal_title：Infection and immunity

authors： Keller GM,Hanson RS,Bergdoll MS

更新日期：1978-04-01 00:00:00

abstract：:The Lyme disease spirochete, Borrelia burgdorferi, is introduced into human hosts via tick bites. Among the cell types present in the skin which may initially contact spirochetes are mast cells. Since spirochetes are known to activate a variety of cell types in vitro, we tested whether B. burgdorferi spirochetes could...

journal_title：Infection and immunity

authors： Talkington J,Nickell SP

更新日期：1999-03-01 00:00:00

abstract：:For the first time, hepatitis A viral antigen (HAAg) was shown in liver biopsy tissue from a patient in the acute phase of hepatitis type A by light and electron microscopy, using the peroxidase-antibody technique. Under light microscopy, the staining for HAAg appeared as a fine, granular reaction product, scattered t...

journal_title：Infection and immunity

authors： Shimizu YK,Shikata T,Beninger PR,Sata M,Setoyama H,Abe H,Tanikawa K

更新日期：1982-04-01 00:00:00

abstract：:Vibrio mimicus 61892, isolated in 1977 from a case of watery diarrhea in Bangladesh, produces an enterotoxin which possesses activity in Y-1 mouse adrenal cells and in rabbit ileal loops which is identical to the prototype cholera toxin (CT) produced by Vibrio cholerae 569B. The neutralization of the adrenal cell acti...

journal_title：Infection and immunity

authors： Spira WM,Fedorka-Cray PJ

更新日期：1983-11-01 00:00:00

abstract：:Vibrio cholerae responds to environmental changes by altering the protein composition of its outer membrane. In rich medium, V. cholerae expresses almost exclusively the outer membrane porin OmpU, whereas in minimal medium, OmpT is the dominant porin. The supplementation of a minimal medium with a mixture of asparagin...

journal_title：Infection and immunity

authors： Mey AR,Craig SA,Payne SM

更新日期：2012-02-01 00:00:00

abstract：:To determine whether lipopolysaccharide (LPS) structures of Campylobacter species are immunologically related to those of 11 other gram-negative organisms, we immunoblotted from polyacrylamide gels the LPS of these strains with immune rabbit serum raised against six Campylobacter jejuni strains and two Campylobacter f...

journal_title：Infection and immunity

authors： Perez-Perez GI,Hopkins JA,Blaser MJ

更新日期：1986-01-01 00:00:00

abstract：:Liver-stage antigen 1 (LSA-1) is a potential vaccine candidate against preerythrocytic stages of malaria. We report here the immunogenicity of linear synthetic constructs delineated as T(H)-cell determinants from the nonrepeat regions of Plasmodium falciparum LSA-1 in murine models and human subjects from areas where ...

journal_title：Infection and immunity

authors： Joshi SK,Bharadwaj A,Chatterjee S,Chauhan VS

更新日期：2000-01-01 00:00:00

abstract：:Tritium-labeled, water-soluble components of Streptococcus pyogenes type M6 absorbed to cardiac tissue in vitro. Tissue binding was time dependent, saturable, and reversible. Chromatography of the crude bacterial extract on Bio-Gel P-300 indicated a molecular weight greater than 300,000 for the heart-binding component...

journal_title：Infection and immunity

authors： Stinson MW,Bergey EJ

更新日期：1982-01-01 00:00:00

abstract：:Mycobacterial growth inhibitory factor (MycoIF), found in supernatant fluids of mouse spleen cell cultures that have been stimulated in vitro with homologous antigen, inhibited the intracellular multiplication of virulent tubercle bacilli within normal mouse peritoneal macrophages in vitro. Antigenically stimulated H...

journal_title：Infection and immunity

authors： Cahall DL,Youmans GP

更新日期：1975-10-01 00:00:00

abstract：:Tuberculosis (TB) remains an enormous global health problem, and a new vaccine against TB more potent than the current inadequate vaccine, Mycobacterium bovis BCG, is urgently needed. We describe a recombinant BCG vaccine (rBCG30) expressing and secreting the 30-kDa major secretory protein of Mycobacterium tuberculosi...

journal_title：Infection and immunity

authors： Horwitz MA,Harth G

更新日期：2003-04-01 00:00:00

abstract：:Patients with chronic bronchitis are colonized by and may develop acute bronchopulmonary infection due to nontypable Haemophilus influenzae (NTHI) despite the presence of bactericidal and opsonizing antibody to the infecting organism. To test the hypothesis that secretory immunoglobulin A (IgA) interferes with host de...

journal_title：Infection and immunity

authors： Musher DM,Goree A,Baughn RE,Birdsall HH

更新日期：1984-07-01 00:00:00

abstract：:Human serum at low concentrations inhibits the growth of Cryptococcus neoformans in vitro. Fractionation of serum yielded a purified inhibitory protein with a molecular mass of approximately 81.8 kDa, a pI of approximately 6.2, and an amino acid sequence that matched that of human transferrin. The inhibitory activity ...

journal_title：Infection and immunity

authors： Sridhar S,Ahluwalia M,Brummer E,Stevens DA

更新日期：2000-06-01 00:00:00

abstract：:Aeromonas salmonicida causes furunculosis in salmonids and is a threat to Atlantic salmon aquaculture. The epithelial surfaces that the pathogen colonizes are covered by a mucus layer predominantly comprised of secreted mucins. By using mass spectrometry to identify mucin glycan structures with and without enzymatic r...

journal_title：Infection and immunity

authors： Padra JT,Sundh H,Sundell K,Venkatakrishnan V,Jin C,Samuelsson T,Karlsson NG,Lindén SK

更新日期：2017-07-19 00:00:00

abstract：:A gene bank of group A Streptococcus strain Manfredo (M protein serotype 5) was constructed with a bacteriophage lambda vector-Escherichia coli K-12 host system and screened by immunoblotting hybrid phage plaques with antisera raised to purified pep M5 (serotype 5 M protein fragment released from the streptococcal cel...

journal_title：Infection and immunity

authors： Kehoe MA,Poirier TP,Beachey EH,Timmis KN

更新日期：1985-04-01 00:00:00

abstract：:Interstitial lung macrophages from tuberculosis-susceptible I/St and tuberculosis-resistant A/Sn mice demonstrated significant constitutive differences in gene expression levels, whereas in vitro infection of these cells with Mycobacterium tuberculosis had only a modulatory impact on gene expression. We conclude that ...

journal_title：Infection and immunity

authors： Orlova MO,Majorov KB,Lyadova IV,Eruslanov EB,M'lan CE,Greenwood CM,Schurr E,Apt AS

更新日期：2006-06-01 00:00:00

abstract：:We report here the identification and characterization of two zinc uptake systems, ZurAM and ZinABC, in the intracellular pathogen Listeria monocytogenes. Transcription of both operons was zinc responsive and regulated by the zinc-sensing repressor Zur. Deletion of either zurAM or zinA had no detectable effect on grow...

journal_title：Infection and immunity

authors： Corbett D,Wang J,Schuler S,Lopez-Castejon G,Glenn S,Brough D,Andrew PW,Cavet JS,Roberts IS

更新日期：2012-01-01 00:00:00

abstract：:Toxoplasma gondii and Neospora caninum (both Apicomplexa) are closely related cyst-forming coccidian parasites that differ significantly in their host ranges and ability to cause disease. Unlike eutherian mammals, Australian marsupials (metatherian mammals) have long been thought to be highly susceptible to toxoplasmo...

journal_title：Infection and immunity

authors： Donahoe SL,Phalen DN,McAllan BM,O'Meally D,McAllister MM,Ellis J,Šlapeta J

更新日期：2017-05-23 00:00:00

abstract：:A T antigen preparation free of trypsin was obtained by application of CNBr-Sepharose linked to pure trypsin. Purification on an ion exchange chromatography column results in an electrophoretically homogeneous preparation of T protein. ...

journal_title：Infection and immunity

authors： Ludwicka A

更新日期：1976-03-01 00:00:00

abstract：:Previous studies have demonstrated that both Ixodes scapularis saliva and Borrelia burgdorferi antigens modulated lymphokines and monokines in vitro. The studies presented here were designed to delineate the role of I. scapularis and B. burgdorferi in modulation of the host immune response in vivo. Infestation of C3H/...

journal_title：Infection and immunity

authors： Zeidner N,Mbow ML,Dolan M,Massung R,Baca E,Piesman J

更新日期：1997-08-01 00:00:00

abstract：:Coxiella burnetii, the agent of Q fever, enters human monocytes through alpha(v)beta(3) integrin and survives inside host cells. In addition, C. burnetii stimulates the synthesis of inflammatory cytokines including tumor necrosis factor (TNF) by monocytes. We studied the role of the interaction of C. burnetii with THP...

journal_title：Infection and immunity

authors： Dellacasagrande J,Ghigo E,Hammami SM,Toman R,Raoult D,Capo C,Mege JL

更新日期：2000-10-01 00:00:00

abstract：:Exposure of PAM cells, a spontaneously transformed mouse cell line, to brain homogenates from mice infected with scrapie caused a relative decrease in total cell yield, which persisted from passage 2 or 3 to passage 18 after treatment. The effect was elicited by each of the eight independent scrapie isolates tested. L...

journal_title：Infection and immunity

authors： Carp RI,Merz GS,Licursi PC

更新日期：1976-07-01 00:00:00

abstract：:Enterohemorrhagic Escherichia coli (EHEC) is a noninvasive food-borne pathogen that colonizes the distal ileum and colon. Proteins encoded in the EHEC locus of enterocyte effacement (LEE) pathogenicity island are known to contribute to this pathogen's adherence to epithelial cells and intestinal colonization. The role...

journal_title：Infection and immunity

authors： Ho TD,Davis BM,Ritchie JM,Waldor MK

更新日期：2008-05-01 00:00:00

abstract：:An immunomodulatory role of arthropod saliva has been well documented, but evidence for an effect on Plasmodium sp. infectiousness remains controversial. Mosquito saliva may orient the immune response toward a Th2 profile, thereby priming a Th2 response against subsequent antigens, including Plasmodium. Orientation to...

journal_title：Infection and immunity

authors： Lawaly R,Konate L,Marrama L,Dia I,Diallo D,Diène Sarr F,Schneider BS,Casademont I,Diallo M,Brey PT,Sakuntabhai A,Mecheri S,Paul R

更新日期：2012-06-01 00:00:00

abstract：:Salmonella spp. and Shigella spp. are responsible for millions of cases of enteric disease each year worldwide. While these pathogens have evolved distinct strategies for interacting with the human intestinal epithelium, they both induce significant proinflammatory responses that result in massive transepithelial migr...

journal_title：Infection and immunity

authors： Mumy KL,Bien JD,Pazos MA,Gronert K,Hurley BP,McCormick BA

更新日期：2008-08-01 00:00:00

abstract：:An important role for immunoglobulin M (IgM) during early acute virulent Toxoplasma gondii infection was identified using IgM-/- mice that lack surface and secretory IgM but maintain normal B-cell functionality and isotype class switching. Following intraperitoneal inoculation with the virulent RH strain, IgM-/- mice ...

journal_title：Infection and immunity

authors： Couper KN,Roberts CW,Brombacher F,Alexander J,Johnson LL

更新日期：2005-12-01 00:00:00

abstract：:A novel in vivo expression technology (IVET) was performed to identify Klebsiella pneumoniae CG43 genes that are specifically expressed during infection of BALB/c mice. The IVET employed a UDP glucose pyrophosphorylase (galU)-deficient mutant of K. pneumoniae which is incapable of utilizing galactose and synthesizing ...

journal_title：Infection and immunity

authors： Lai YC,Peng HL,Chang HY

更新日期：2001-11-01 00:00:00

abstract：:Classical and El Tor strains of Vibrio cholerae were examined for production of bacteriophage or bacteriophage-related material by electron microscopy of mitomycin C-induced cultures. The strains were also tested for pathogenicity by using the ligated ileal loops of adult rabbits. Of the 27 strains tested, 25 showed a...

journal_title：Infection and immunity

authors： Parker C,Richardson SH,Romig WR

更新日期：1970-04-01 00:00:00