Type 2 secretion promotes enterohemorrhagic Escherichia coli adherence and intestinal colonization.

abstract：:Live or heat-killed cells of Streptococcus mutans specifically adhere to dextran previously synthesized on glass surfaces by the action of extracellular dextransucrase. ...

journal_title：Infection and immunity

authors： Kuramitsu HK

更新日期：1974-04-01 00:00:00

abstract：:The primary antibody response of BALB/c splenocytes to sheep erythrocytes in vitro was suppressed by infection with Friend leukemia virus (FLV), with the response capacity decreasing with increasing duration of infection. The acquisition of normal antibody responses was amplified by macrophage-produced antibody respon...

journal_title：Infection and immunity

authors： Butler RC,Frier JM,Chapekar MS,Graham MO,Friedman H

更新日期：1983-03-01 00:00:00

abstract：:Antibodies against the class 4 outer membrane protein (OMP) from Neisseria meningitidis have been purified from sera from vaccinees immunized with the Norwegian meningococcal group B outer membrane vesicle vaccine. The human sera and purified antibodies reacted strongly with the class 4 OMP in immunoblots, whereas exp...

journal_title：Infection and immunity

authors： Rosenqvist E,Musacchio A,Aase A,Høiby EA,Namork E,Kolberg J,Wedege E,Delvig A,Dalseg R,Michaelsen TE,Tommassen J

更新日期：1999-03-01 00:00:00

abstract：:The complete nucleotide sequence of a 612-base-pair DNA fragment containing the gene for the major fimbrial subunit of CS3 of enterotoxigenic Escherichia coli is presented. A possible promoter region, a ribosome-binding site, and two potential signal peptidase cleavage sites are indicated. Unlike the best-studied fimb...

journal_title：Infection and immunity

authors： Boylan M,Smyth CJ,Scott JR

更新日期：1988-12-01 00:00:00

abstract：:The recently introduced choleragen-induced rat foot edema model has been employed as a bioassay for evaluating the immunogenicity of three purified preparations containing cholera exo-enterotoxin antigen, choleragen, choleragenoid, and Formalin-treated choleragen (formagen). The results indicated that choleragen evoke...

journal_title：Infection and immunity

authors： Finkelstein RA,Hollingsworth RC

更新日期：1970-05-01 00:00:00

abstract：:A cytotoxin was found in culture filtrates of a number of Escherichia coli strains that differed from the known heat-stable and heat-labile enterotoxins of E. coli. It was cytotoxic for Vero but not for Y-1 or CHO cells, and its effect on Vero was distinctly different from that of heat-labile enterotoxin. It was labil...

journal_title：Infection and immunity

authors： Konowalchuk J,Speirs JI,Stavric S

更新日期：1977-12-01 00:00:00

abstract：:The nucleotide sequence of the chromosomal DNA flanking the Actinomyces naeslundii (formerly A. viscosus) T14V type 1 fimbrial structural subunit gene (fimP) was determined. Six open reading frames (ORFs), in the order 5' ORF3, ORF2, ORF1,fimP, ORF4, ORF5, ORF6 3', were identified. ORF1 encoded a protein of 408 amino ...

journal_title：Infection and immunity

authors： Yeung MK,Ragsdale PA

更新日期：1997-07-01 00:00:00

abstract：:Borrelia burgdorferi-induced arthritis in mice is characterized by tendonitis, synovitis, and inflammatory-cell infiltrate, predominantly of neutrophils. Because genetic deficiency in E and P selectins results in delayed recruitment of neutrophils to sites of inflammation, mice with this deficiency were tested for the...

journal_title：Infection and immunity

authors： Seiler KP,Ma Y,Weis JH,Frenette PS,Hynes RO,Wagner DD,Weis JJ

更新日期：1998-09-01 00:00:00

abstract：:A murine model system was established to study immune responses to the Pnu-Imune vaccine, which is made up of 23 different pneumococcal capsular polysaccharides. In this animal model, antibody-forming cell responses to 21 of 23 individual polysaccharides in the vaccine were detected. The Pnu-Imune vaccine elicited goo...

journal_title：Infection and immunity

authors： Garg M,Subbarao B

更新日期：1992-06-01 00:00:00

abstract：:Adult volunteers received a booster dose (4 x 10(8) CFU) of attenuated Vibrio cholerae CVD 103-HgR oral vaccine 15 or 24 months after primary immunization. The immune response was modest, presumably due to rapid clearance of the vaccine strain by a primed immune system. ...

journal_title：Infection and immunity

authors： Cryz SJ Jr,Levine MM,Losonsky G,Kaper JB,Althaus B

更新日期：1992-09-01 00:00:00

abstract：:In order to evaluate during experimental Trypanosoma brucei infections the potential role of tumor necrosis factor alpha (TNF-alpha) in the host-parasite interrelationship, C57BL/6 TNF-alpha knockout mice (TNF-alpha-/-) as well as C57BL/6 wild-type mice were infected with pleomorphic T. brucei AnTat 1.1 E parasites. I...

journal_title：Infection and immunity

authors： Magez S,Radwanska M,Beschin A,Sekikawa K,De Baetselier P

更新日期：1999-06-01 00:00:00

abstract：:We investigated the role of bacterial mannose-resistant fimbriation of S fimbriae (Fim), mannose-resistant hemagglutination (S-Mrh), and hemolysin (Hly) production by an Escherichia coli parent and genetically cloned strains as regards their effect on histamine release from rat mast cells and generation of the chemilu...

journal_title：Infection and immunity

authors： König B,König W,Scheffer J,Hacker J,Goebel W

更新日期：1986-12-01 00:00:00

abstract：:Thrombospondin-related anonymous protein (TRAP) of the malaria parasite Plasmodium falciparum shares two sequence motifs with other proteins which possess adhesive properties. Recently, findings indicate that TRAP is an antigen which contributes to antisporozoite immunity. We have cloned and expressed the TRAP coding ...

journal_title：Infection and immunity

authors： Scarselli E,Tolle R,Koita O,Diallo M,Müller HM,Früh K,Doumbo O,Crisanti A,Bujard H

更新日期：1993-08-01 00:00:00

abstract：:When type I Candida stellatoidea is plated onto sucrose agar at levels in excess of 10(8) cells, some isolates spontaneously form sucrose-positive colonies. These isolates do not display typical type I phenotypes but instead exhibit phenotypes intermediate between type I C. stellatoidea and C. albicans. Also, this phe...

journal_title：Infection and immunity

authors： Wickes BL,Golin JE,Kwon-Chung KJ

更新日期：1991-05-01 00:00:00

abstract：:Murine monoclonal antibodies were generated against streptolysin O. One out of 10 tested immunoglobulin clones exhibited strong neutralizing activity; in solution, the presence of approximately two to four antibody molecules per toxin monomer effected 50% neutralization of hemolytic toxin activity. An enzyme-linked im...

journal_title：Infection and immunity

authors： Hugo F,Reichwein J,Arvand M,Krämer S,Bhakdi S

更新日期：1986-12-01 00:00:00

abstract：:The LuxS protein is required for the biosynthesis of the type 2 autoinducer (AI-2), which is involved in quorum sensing in a wide range of bacterial species. We have determined the effects of a defined luxS mutation on the virulence of Streptococcus pneumoniae. Although the luxS mutant displayed reduced virulence rela...

journal_title：Infection and immunity

authors： Stroeher UH,Paton AW,Ogunniyi AD,Paton JC

更新日期：2003-06-01 00:00:00

abstract：:The genome of Borrelia burgdorferi, the etiologic agent of Lyme disease, is composed of a linear chromosome and more than 20 linear and circular plasmids. Typically, plasmid content analysis has been carried out by pulsed-field gel electrophoresis and confirmed by Southern hybridization. However, multiple plasmids of ...

journal_title：Infection and immunity

authors： Iyer R,Kalu O,Purser J,Norris S,Stevenson B,Schwartz I

更新日期：2003-07-01 00:00:00

abstract：:Streptococcus pneumoniae infections of the lung are associated with significant damage to the alveolar epithelium. Host phagocytes and pneumolysin, a cytolytic toxin of S. pneumoniae, are believed to contribute to this cellular damage, yet experiments in which these elements are absent demonstrate the presence of an a...

journal_title：Infection and immunity

authors： Duane PG,Rubins JB,Weisel HR,Janoff EN

更新日期：1993-10-01 00:00:00

abstract：:Bordetella parapertussis, a respiratory tract pathogen commonly regarded as noninvasive, was found to invade HeLa 229 cell monolayers. Following treatment of the monolayers with gentamicin, numbers of viable B. parapertussis recovered were comparable to those of invasive Salmonella and Shigella isolates. Invasion occu...

journal_title：Infection and immunity

authors： Ewanowich CA,Sherburne RK,Man SF,Peppler MS

更新日期：1989-04-01 00:00:00

abstract：:Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection (STI) gonorrhea, is a growing public health threat for which a vaccine is urgently needed. We characterized the functional role of the gonococcal MetQ protein, which is the methionine binding component of an ABC transporter system, and as...

journal_title：Infection and immunity

authors： Semchenko EA,Day CJ,Seib KL

更新日期：2017-01-26 00:00:00

abstract：:Lysogenic conversion of Shigella flexneri type antigens was studied with the aid of wild-type and thermosensitive mutant phages. With all wild-type phages, the appearance of glycosylated antigen was accompanied by the appearance of polyprenyl phosphate glucose synthetase activity. With some of the mutant phages, the a...

journal_title：Infection and immunity

authors： Financsek I,Ketyi I,Sasak W,Jankowski W,Janczura E,Chojnacki T

更新日期：1976-12-01 00:00:00

abstract：:Lung dendritic cells were identified by immunohistochemistry in lung tissue sections from C57BL/6 mice. Following isolation from the lungs using CD11c magnetic beads, the flow cytometric analysis of I-A(b+) and CD11c(+) cells indicated a mixed population of dendritic cells at different stages of maturation, with most ...

journal_title：Infection and immunity

authors： Gonzalez-Juarrero M,Orme IM

更新日期：2001-02-01 00:00:00

abstract：:Pseudomonas aeruginosa is a leading cause of hospital-acquired pneumonia and chronic lung infections in cystic fibrosis patients. Iron is essential for bacterial growth, and P. aeruginosa expresses multiple iron uptake systems, whose role in lung infection deserves further investigation. P. aeruginosa Fe(3+) uptake sy...

journal_title：Infection and immunity

authors： Minandri F,Imperi F,Frangipani E,Bonchi C,Visaggio D,Facchini M,Pasquali P,Bragonzi A,Visca P

更新日期：2016-07-21 00:00:00

abstract：:Thirty-two clinical isolates of Shiga-like toxin (SLT)-producing Escherichia coli associated with single cases or outbreaks of bloody diarrhea, hemorrhagic colitis, the hemolytic uremic syndrome, or edema disease of swine were examined for multiple copies of genes belonging to the slt-I or slt-II toxin families. Five ...

journal_title：Infection and immunity

authors： Schmitt CK,McKee ML,O'Brien AD

更新日期：1991-03-01 00:00:00

abstract：:Previous studies have suggested that interleukin-4 (IL-4) has a protective effect in host defense to Borrelia burgdorferi infection, both in limiting the severity of arthritis and in controlling spirochete numbers in tissues, and a mapping study revealed suggestive linkage to a cluster of genes on mouse chromosome 11,...

journal_title：Infection and immunity

authors： Potter MR,Noben-Trauth N,Weis JH,Teuscher C,Weis JJ

更新日期：2000-10-01 00:00:00

abstract：:Bordetella pertussis extract that contained adenylate cyclase toxin produced large increases in human neutrophil cyclic AMP levels and inhibited their oxidative burst, as reflected by luminol-enhanced chemiluminescence and superoxide release. The adenylate cyclase toxin-containing extract blocked neutrophil-mediated i...

journal_title：Infection and immunity

authors： Galgiani JN,Hewlett EL,Friedman RL

更新日期：1988-04-01 00:00:00

abstract：:Nontypeable Haemophilus influenzae (NTHi) is a commensal microorganism of the human nasopharynx, and yet is also an opportunistic pathogen of the upper and lower respiratory tracts. Host microenvironments influence gene expression patterns, likely critical for NTHi persistence. The host sequesters iron as a mechanism ...

journal_title：Infection and immunity

authors： Harrison A,Santana EA,Szelestey BR,Newsom DE,White P,Mason KM

更新日期：2013-04-01 00:00:00

abstract：:Infectious agents are often considered potential triggers of chronic inflammatory disease, including autoimmunity; however, direct evidence is usually lacking. Here we show that following control of acute infection of mice with the myotropic Colombiana strain of Trypanosoma cruzi, parasites persisted in tissue at low ...

journal_title：Infection and immunity

authors： Roffê E,Marino APMP,Weaver J,Wan W,de Araújo FF,Hoffman V,Santiago HC,Murphy PM

更新日期：2016-03-24 00:00:00

abstract：:Whooping cough results from infection of the respiratory tract with Bordetella pertussis, and the secreted adenylate cyclase toxin (ACT) is essential for the bacterium to establish infection. Despite extensive study of the mechanism of ACT cytotoxicity and its effects over a range of concentrations in vitro, ACT has n...

journal_title：Infection and immunity

authors： Eby JC,Gray MC,Warfel JM,Paddock CD,Jones TF,Day SR,Bowden J,Poulter MD,Donato GM,Merkel TJ,Hewlett EL

更新日期：2013-05-01 00:00:00

abstract：:Neospora caninum is a recently identified coccidian parasite which shares many features with, but is clearly distinct from, Toxoplasma gondii. N. caninum tachyzoites infect a wide range of mammalian cells both in vivo and in vitro. The mechanisms by which infection is achieved are largely unknown. Recent evidence has ...

journal_title：Infection and immunity

authors： Hemphill A

更新日期：1996-10-01 00:00:00