Subcellular localization and functional characterization of Nc-p43, a major Neospora caninum tachyzoite surface protein.

abstract：:Immunity to reinfection in the genital tract of female guinea pigs with the agent of guinea pig inclusion conjunctivitis was found to be dependent upon an intact humoral immune response. Cell-mediated immunity in the absence of humoral immunity had no apparent role in resistance to challenge infection. ...

journal_title：Infection and immunity

authors： Rank RG,Barron AL

更新日期：1983-01-01 00:00:00

abstract：:Amastigotes obtained from spleens of mice infected with different strains of Trypanosoma cruzi were examined for their ability to invade macrophages and L929 cells and to initiate infection in mice. Both types of cells were readily invaded by organisms of the strains Y, MR, and Tulahuen. Organisms of the CL strain wer...

journal_title：Infection and immunity

authors： McCabe RE,Remington JS,Araujo FG

更新日期：1984-11-01 00:00:00

abstract：:We have constructed an improved recombination-based in vivo expression technology (RIVET) and used it as a screening method to identify Vibrio cholerae genes that are transcriptionally induced during infection of infant mice. The improvements include the introduction of modified substrate cassettes for resolvase that ...

journal_title：Infection and immunity

authors： Osorio CG,Crawford JA,Michalski J,Martinez-Wilson H,Kaper JB,Camilli A

更新日期：2005-02-01 00:00:00

abstract：:Stenotrophomonas maltophilia is a ubiquitous bacterium and an emerging nosocomial pathogen. This bacterium is resistant to many antibiotics, associated with a number of infections, and a significant health risk, especially for immunocompromised patients. Given that Caenorhabditis elegans shares many conserved genetic ...

journal_title：Infection and immunity

authors： White CV,Darby BJ,Breeden RJ,Herman MA

更新日期：2015-12-07 00:00:00

abstract：:Differences in infection kinetics and host response between Burkholderia multivorans and Burkholderia cenocepacia were demonstrated in a pulmonary infection model in BALB/c mice. B. multivorans persisted in the lung, while B. cenocepacia was cleared. Indirect immunofluorescence and electron microscopy of B. multivoran...

journal_title：Infection and immunity

authors： Chu KK,MacDonald KL,Davidson DJ,Speert DP

更新日期：2004-10-01 00:00:00

abstract：:The antigens of Haemophilus somnus recognized by convalescent bovine serum were studied by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotting with a protein A-peroxidase conjugate. The same two 76K and 40K antigens were predominant in whole-bacterium preparations and in outer-membrane-enric...

journal_title：Infection and immunity

authors： Corbeil LB,Arthur JE,Widders PR,Smith JW,Barbet AF

更新日期：1987-06-01 00:00:00

abstract：:A better knowledge on how immune responses are initiated in mucosal tissues would facilitate the design of new mucosal vaccines, as well as improve our understanding on host defense against infection. We investigated the mechanisms of adjuvanticity of the Mycoplasma-derived macrophage-activating 2-kDa lipopeptide (MAL...

journal_title：Infection and immunity

authors： Rharbaoui F,Westendorf A,Link C,Felk S,Buer J,Gunzer M,Guzmán CA

更新日期：2004-12-01 00:00:00

abstract：:Sporothrix schenckii is a human pathogen that causes sporotrichosis, an important cutaneous mycosis with a worldwide distribution. It produces dark-brown conidia, which infect the host. We found that S. schenckii synthesizes melanin via the 1,8-dihydroxynaphthalene pentaketide pathway. Melanin biosynthesis in the wild...

journal_title：Infection and immunity

authors： Romero-Martinez R,Wheeler M,Guerrero-Plata A,Rico G,Torres-Guerrero H

更新日期：2000-06-01 00:00:00

abstract：:The viaB locus coding for the Vi antigen of Salmonella typhi Ty2 was cloned on a 40.6-kilobase fragment into the cosmid vector pHC79. The live, oral, attenuated Vi-negative S. typhi Ty21a vaccine strain was transformed with the recombinant cosmid encoding the viaB locus. Homologous recombination of the viaB locus into...

journal_title：Infection and immunity

authors： Cryz SJ Jr,Fürer E,Baron LS,Noon KF,Rubin FA,Kopecko DJ

更新日期：1989-12-01 00:00:00

abstract：:Recent efforts to develop a vaccine against the diarrheal disease cholera have focused on the use of live attenuated strains of the causative organism, Vibrio cholerae. The Ogawa lipopolysaccharide phenotype is expressed by many epidemic strains, and motility defects reduce the risk of reactive diarrhea in vaccine rec...

journal_title：Infection and immunity

authors： Chiang SL,Mekalanos JJ

更新日期：2000-11-01 00:00:00

abstract：:Identification of antigenically conserved surface components of Haemophilus ducreyi may facilitate the development of reagents to diagnose and prevent chancroid. A hybridoma derived from a mouse immunized with nontypeable Haemophilus influenzae produced a monoclonal antibody (MAb), designated 3B9, that bound to 35 of ...

journal_title：Infection and immunity

authors： Spinola SM,Griffiths GE,Bogdan J,Menegus MA

更新日期：1992-02-01 00:00:00

abstract：:Bactericidal activity and binding of a 57,000-dalton cationic antimicrobial neutrophil granule protein (CAP57) are determined by the presence on bacteria of O-antigen polysaccharide chains and the availability of negatively charged groups in the lipid A region, the inner core region, or both regions of lipopolysacchar...

journal_title：Infection and immunity

authors： Farley MM,Shafer WM,Spitznagel JK

更新日期：1988-06-01 00:00:00

abstract：:Using the indirect fluorescein-labeled and indirect peroxidase-antiperoxidase-labeled immunohistochemical techniques, and utilizing both antiserum specific for the beta-subunit of choriogonadotropin and antiserum for the total hormone, we have demonstrated the presence of a choriogonadotropin-like immunoreactive mater...

journal_title：Infection and immunity

authors： Acevedo HF,Slifkin M,Pouchet-Melvin GR,Campbell-Acevedo EA

更新日期：1979-06-01 00:00:00

abstract：:Streptococcus suis capsular type 2 is an important etiological agent of swine meningitis, and it is also a zoonotic agent. Since one hypothesis of the pathogenesis of S. suis infection is that bacteria enter the bloodstream and invade the meninges and other tissues in close association with mononuclear phagocytes, the...

journal_title：Infection and immunity

authors： Segura M,Gottschalk M

更新日期：2002-08-01 00:00:00

abstract：:Capsular types 5 and 8, which account for about 70% of Staphylococcus aureus strains isolated from the blood of patients, resisted in vitro phagocytosis by human polymorphonuclear leukocytes (PMN). Antisera and monoclonal antibody to type 5 and 8 capsular polysaccharides (CPS) induced type-specific in vitro phagocytos...

journal_title：Infection and immunity

authors： Karakawa WW,Sutton A,Schneerson R,Karpas A,Vann WF

更新日期：1988-05-01 00:00:00

abstract：:Lipopolysaccharide (LPS) binding protein (LBP) is an acute-phase protein that enhances the responsiveness of immune cells to LPS by virtue of its capacity to transfer LPS to CD14. To determine the role of LBP in the innate immune response to peritonitis, LBP gene-deficient (LBP(-/-)) and normal wild-type mice were int...

journal_title：Infection and immunity

authors： Knapp S,de Vos AF,Florquin S,Golenbock DT,van der Poll T

更新日期：2003-12-01 00:00:00

abstract：:The Haemophilus ducreyi 35000HP genome encodes a homolog of the CpxRA two-component cell envelope stress response system originally characterized in Escherichia coli. CpxR, the cytoplasmic response regulator, was shown previously to be involved in repression of the expression of the lspB-lspA2 operon (M. Labandeira-Re...

journal_title：Infection and immunity

authors： Labandeira-Rey M,Brautigam CA,Hansen EJ

更新日期：2010-11-01 00:00:00

abstract：:C57BL/6 mice were infected intravenously with 6 X 10(3) Listeria monocytogenes organisms. As early as day 3 of infection, there was a marked reduction in the number of lymphocytes recovered from the peripheral blood, bone marrow, and thymuses of infected animals. Concomitantly, there was an increase in the number of s...

journal_title：Infection and immunity

authors： Watson SR,Redington TJ,Miller TB,Bullock WE

更新日期：1984-08-01 00:00:00

abstract：:A preparation procedure for scanning electron microscopy was developed by which gononcoccal colonies can be studied directly on the agar surface. After glutaraldehyde fixation directly in petri dishes, small agar pieces were cut out and dehydrated stepwise in increasing concentrations of ethanol. The blocks were there...

journal_title：Infection and immunity

authors： Elmros T,Hörstedt P,Winblad B

更新日期：1975-09-01 00:00:00

abstract：:Haemophilus influenzae is a commensal and opportunistic pathogen of the human airways. A number of surface molecules contribute to colonization of the airways by H. influenzae, such as adhesins, including structures found in the lipooligosaccharide (LOS). A human bronchiolar xenograft model was employed to investigate...

journal_title：Infection and immunity

authors： Swords WE,Chance DL,Cohn LA,Shao J,Apicella MA,Smith AL

更新日期：2002-08-01 00:00:00

abstract：:Antigens extracted from cells of Streptococcus pyogenes T6 and Streptococcus mutans strains AHT, BHT, 10449, OMZ175, and K1R adsorbed to the sarcolemmal sheath of cardiac muscle cells in vitro. Similar preparations from S. salivarius, S. sanguis, Staphylococcus aureus, and Lactobacillus casei had weak or negligible ti...

journal_title：Infection and immunity

authors： Stinson MW,Nisengard RJ,Bergey EJ

更新日期：1980-02-01 00:00:00

abstract：:The interaction between human neutrophils and wild-type Bordetella pertussis or mutants expressing altered lipopolysaccharide or lacking virulence factors-pertussis toxin, adenylate cyclase toxin, dermonecrotic toxin, filamentous hemagglutinin (FHA), pertactin, or BrkA-was examined. In the absence of antibodies, the w...

journal_title：Infection and immunity

authors： Weingart CL,Weiss AA

更新日期：2000-03-01 00:00:00

abstract：:Two distinct types of granulomas were produced in the draining lymph nodes by immunizing guinea pigs with Mycobacterium bovis BCG or Mycobacterium leprae, as reported earlier (Narayanan et al., J. Pathol. 134:253-265, 1981). In the BCG-induced granuloma there is successful containment, killing, and degradation of the ...

journal_title：Infection and immunity

authors： Mathew RC,Katayama I,Gupta SK,Curtis J,Turk JL

更新日期：1983-01-01 00:00:00

abstract：:Significant resistance against influenza virus and Mycobacterium tuberculosis infections was induced when trehalose dimycolate from M. tuberculosis or M. bovis but not M. avium was combined with muramyl dipeptide. Trehalose dimycolate from M. tuberculosis, in contrast to that from M. avium, could confer resistance aga...

journal_title：Infection and immunity

authors： Masihi KN,Brehmer W,Lange W,Werner H,Ribi E

更新日期：1985-12-01 00:00:00

abstract：:A crude complex containing group C polysaccharide, outer membrane proteins, and lipopolysaccharide (LPS) was isolated from the cell-free culture liquid of Neisseria meningitidis serogroup C, serotype 2a. Group C polysaccharide and LPS were removed from this complex, resulting in an outer membrane complex and a purifie...

journal_title：Infection and immunity

authors： Beuvery EC,Miedema F,van Delft RW,Haverkamp J,Leussink AB,te Pas BJ,Teppema KS,Tiesjema RH

更新日期：1983-04-01 00:00:00

abstract：:Erythrocytic malaria parasites degrade hemoglobin as a principal source of amino acids for parasite protein synthesis. We have previously shown that a Plasmodium falciparum trophozoite cysteine proteinase, now termed falcipain, is required for hemoglobin degradation, and we have hypothesized that this proteinase is re...

journal_title：Infection and immunity

authors： Salas F,Fichmann J,Lee GK,Scott MD,Rosenthal PJ

更新日期：1995-06-01 00:00:00

abstract：:Recently, a glycoprotein fraction, designated gp10/20, purified from Leishmania mexicana amazonensis was shown to induce a cellular immune response mediated by murine L3T4+ T lymphocytes. This fact led us to pursue further the characterization of this fraction. The present study demonstrated that gp10/20 is a degradat...

journal_title：Infection and immunity

authors： Rodrigues MM,Xavier MT,Mendonça-Previato L,Barcinski MA

更新日期：1988-07-01 00:00:00

abstract：:Minimally manipulated nasal secretions, an accessible form of airway surface fluid, were tested against indigenous and added bacteria by using CFU assays. Antimicrobial activity was found to vary between donors and with different target bacteria and was markedly diminished by dilution of the airway secretions. Donor-t...

journal_title：Infection and immunity

authors： Cole AM,Dewan P,Ganz T

更新日期：1999-07-01 00:00:00

abstract：:The protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide (CP5) was examined in a modified model of catheter-induced endocarditis. Rats were catheterized by surgically passing a polyethylene catheter through the right carotid artery and aortic valve into the left ventricle. The ...

journal_title：Infection and immunity

authors： Lee JC,Park JS,Shepherd SE,Carey V,Fattom A

更新日期：1997-10-01 00:00:00

abstract：:Both rat alveolar macrophages and a human macrophages cell line with characteristics of human tissue (e.g., alveolar) macrophages (THP-1) were found to inhibit the germination of Rhizopus spores. However, the conditions under which fungistatic activity occurs are different for these two cell types. The inhibition of R...

journal_title：Infection and immunity

authors： Jorens PG,Boelaert JR,Halloy V,Zamora R,Schneider YJ,Herman AG

更新日期：1995-11-01 00:00:00