Flow microfluorometry analysis of alterations in T-lymphocyte subsets during murine listeriosis.

abstract：:Glycosylphosphatidylinositol (GPI)-anchored proteins are abundantly expressed in the infective and intracellular stages of Trypanosoma cruzi and are recognized as antigenic targets by both the humoral and cellular arms of the immune system. Previously, we demonstrated the efficacy of genes encoding GPI-anchored protei...

journal_title：Infection and immunity

authors： Bhatia V,Sinha M,Luxon B,Garg N

更新日期：2004-11-01 00:00:00

abstract：:The major merozoite surface protein of Plasmodium falciparum (PfMSP1) is a candidate antigen for a malaria vaccine. A 19-kDa C-terminal processing product of PfMSP1 (PfMSP1(19)) is composed of two domains sharing a cysteine-rich motif with epidermal growth factor (EGF) and is the target of monoclonal antibodies which ...

journal_title：Infection and immunity

authors： Egan AF,Chappel JA,Burghaus PA,Morris JS,McBride JS,Holder AA,Kaslow DC,Riley EM

更新日期：1995-02-01 00:00:00

abstract：:Protective immunity against Babesia bigemina is hypothesized to involve antibodies directed against merozoite surface-exposed epitopes. Levels of antibody against a rhoptry-associated protein 1 (RAP-1) B-lymphocyte epitope, defined by surface-reactive and inhibitory monoclonal antibodies, in immune cattle sera were de...

journal_title：Infection and immunity

authors： Ushe TC,Palmer GH,Sotomayor L,Figueroa JV,Buening GM,Perryman LE,McElwain TF

更新日期：1994-12-01 00:00:00

abstract：:Brucella abortus injected into CBA mice replicated primarily in the spleen and liver, reaching a peak bacterial count in both organs about 7 days postinfection. The organism was eliminated from the liver but declined to a chronic phase in the spleen. The infection caused hepatosplenomegaly. An influx of macrophages in...

journal_title：Infection and immunity

authors： Doyle AG,Halliday WJ,Barnett CJ,Dunn TL,Hume DA

更新日期：1992-04-01 00:00:00

abstract：:Numerous investigations have shown that 70-kDa heat shock protein (Hsp70) homologs interact tightly with hydrophobic proteins and functionally assist proteins in membranous organelles and environments. One such protein is the Chlamydia trachomatis Hsp70 that is associated with isolated outer membrane complexes of infe...

journal_title：Infection and immunity

authors： Raulston JE,Davis CH,Paul TR,Hobbs JD,Wyrick PB

更新日期：2002-02-01 00:00:00

abstract：:Amastigotes obtained from spleens of mice infected with different strains of Trypanosoma cruzi were examined for their ability to invade macrophages and L929 cells and to initiate infection in mice. Both types of cells were readily invaded by organisms of the strains Y, MR, and Tulahuen. Organisms of the CL strain wer...

journal_title：Infection and immunity

authors： McCabe RE,Remington JS,Araujo FG

更新日期：1984-11-01 00:00:00

abstract：:The unique permissiveness of A/J mouse macrophages for replication of Legionella pneumophila is caused by a deficiency in the Nod-like receptor (NLR) protein and intracellular sensor for L. pneumophila flagellin (Naip5). The signaling pathways and proteins activated by Naip5 sensing in macrophages were investigated. T...

journal_title：Infection and immunity

authors： Fortier A,Doiron K,Saleh M,Grinstein S,Gros P

更新日期：2009-11-01 00:00:00

abstract：:Molecular approaches to the rapid analysis of the serotyping antigens of Neisseria meningitidis, the class 2 and 3 outer membrane proteins (OMPs), were developed, evaluated, and used to study 12 antigenic variants of these proteins. A primer set for the polymerase chain reaction (PCR) amplification of the genes encodi...

journal_title：Infection and immunity

authors： Feavers IM,Suker J,McKenna AJ,Heath AB,Maiden MC

更新日期：1992-09-01 00:00:00

abstract：:Four strains of Staphylococcus aureus of a phage type other than the second group, isolated from patients with impetigo and Ritter's disease, were found to produce an exotoxin similar to those reported by Melish et al. (1972), Kapral and Miller (1971), and Arbuthnott et al. (1973). This toxin could elicit a general ex...

journal_title：Infection and immunity

authors： Kondo I,Sakurai S,Sarai Y

更新日期：1974-10-01 00:00:00

abstract：:Bordetella pertussis, the etiological agent of whooping cough, has the ability to modulate its phenotype in response to environmental conditions by using the BvgAS sensory transduction system which is encoded by the vir locus (now known as bvg). The BvgAS system is part of a large family of two-component sensory trans...

journal_title：Infection and immunity

authors： Stenson TH,Peppler MS

更新日期：1995-10-01 00:00:00

abstract：:The mechanism of in vitro synergistic lysis of sheep erythrocytes by Corynebacterium ovis and Corynebacterium equi was investigated. Hemolysis required (i) the action of phospholipase D from C. ovis, (ii) the action of an extracellular protein of C. equi, and (iii) Mg2+. Maximum lysis required imposition on the system...

journal_title：Infection and immunity

authors： Bernheimer AW,Linder R,Avigad LS

更新日期：1980-07-01 00:00:00

abstract：:Apical membrane antigen 1 (AMA-1) is an invasion-related Plasmodium antigen that is expressed during both intracellular and extracellular asexual stages of the parasite's life cycle, making it an ideal target for induction of humoral and cellular immune responses that can protect against malaria. We show here that whe...

journal_title：Infection and immunity

authors： Bouillet LÉ,Dias MO,Dorigo NA,Moura AD,Russell B,Nosten F,Renia L,Braga EM,Gazzinelli RT,Rodrigues MM,Soares IS,Bruna-Romero O

更新日期：2011-09-01 00:00:00

abstract：:In its canonical role the reverse transcriptase telomerase recovers the telomeric repeats that are lost during DNA replication. Other locations and activities have been recently described for the telomerase protein subunit TERT in mammalian cells. In the present work, using biochemistry, molecular biology, and electro...

journal_title：Infection and immunity

authors： Campelo R,Díaz Lozano I,Figarella K,Osuna A,Ramírez JL

更新日期：2015-01-01 00:00:00

abstract：:Bacteroides fragilis with enterotoxin-like activity (BFEL) was isolated from the feces of 24- to 48-h-old lambs with acute diarrheal disease on three different sheep ranches in the Northern Rocky Mountain region of the United States. The lamb intestinal loop test was used to enrich for the bacterium before its initial...

journal_title：Infection and immunity

authors： Myers LL,Firehammer BD,Shoop DS,Border MM

更新日期：1984-05-01 00:00:00

abstract：:Helicobacter pylori infection is thought to be involved in the development of several gastric diseases. Two H. pylori virulence factors (vacuolating cytotoxin A and cytotoxin-associated gene A) reportedly interact with lipid rafts in gastric epithelial cells. The role of Toll-like receptor (TLR)-mediated signaling in ...

journal_title：Infection and immunity

authors： Lu DY,Chen HC,Yang MS,Hsu YM,Lin HJ,Tang CH,Lee CH,Lai CK,Lin CJ,Shyu WC,Lin FY,Lai CH

更新日期：2012-05-01 00:00:00

abstract：:Cell-free hemoglobin (Hb) is being developed as an erythrocyte substitute. We have previously demonstrated that cell-free Hb is an endotoxin-binding protein which disaggregates endotoxin and subsequently increases the biological activity of endotoxin in several in vitro assays. Because much of the morbidity and mortal...

journal_title：Infection and immunity

authors： Su D,Roth RI,Yoshida M,Levin J

更新日期：1997-04-01 00:00:00

abstract：:The survival of Staphylococcus aureus in the lungs of mice was studied under various conditions. Doses of 10(7) to 10(9) washed staphylococci were quantitatively introduced into the lungs after intratracheal inoculation in mice under either ether or sodium pentobarbital anesthesia. Mice were sacrificed at intervals, t...

journal_title：Infection and immunity

authors： DeMaria TF,Kapral FA

更新日期：1978-07-01 00:00:00

abstract：:Hybridomas secreting monoclonal antibodies against an apparent strain-specific cell surface antigen of Neisseria gonorrhoeae were produced. Spleen cells from BALB/c mice immunized with whole gonococci were fused with mouse myeloma cell line Sp2/0, and hybrid cells were selected in culture. One hybridoma that secreted ...

journal_title：Infection and immunity

authors： Nachamkin I,Cannon JG,Mittler RS

更新日期：1981-05-01 00:00:00

abstract：:Bovine septicemic Escherichia coli 31A agglutinates bovine, rabbit, and human erythrocytes and adheres in vitro to the brush border of bovine or ovine intestinal epithelial cells and to the human colon carcinoma Caco-2 cell line. The adhesion and hemagglutination of E. coli 31A are mediated by a chromosome-encoded fim...

journal_title：Infection and immunity

authors： Bertin Y,Girardeau JP,Darfeuille-Michaud A,Contrepois M

更新日期：1996-01-01 00:00:00

abstract：:Using polystyrene microspheres coated with heparin or heparan sulfate, it was shown that coated microspheres specifically bound eukaryotic cells and were endocytosed by nonprofessional phagocytic cells. Coated microspheres displayed properties of binding to eukaryotic cells that were similar to those of chlamydiae, an...

journal_title：Infection and immunity

authors： Stephens RS,Fawaz FS,Kennedy KA,Koshiyama K,Nichols B,van Ooij C,Engel JN

更新日期：2000-03-01 00:00:00

abstract：:A DNA microarray containing fragments of 137 Borrelia burgdorferi B31 putative lipoprotein genes was used to examine Lyme disease spirochetes. DNA from B. burgdorferi sensu stricto B31, 297, and N40; Borrelia garinii IP90; and Borrelia afzelii P/Gau was fluorescently labeled and hybridized to the microarray, demonstra...

journal_title：Infection and immunity

authors： Liang FT,Nelson FK,Fikrig E

更新日期：2002-06-01 00:00:00

abstract：:Peroxidase-conjugated antibodies were found to be as sensitive as those conjugated to fluorescein-isothiocyanate (FITC) for identification of selected enterovirus types by the indirect technique. Peroxidase conjugates, however, were found to give fewer nonspecific reactions. The reasons for the higher specificity of t...

journal_title：Infection and immunity

authors： Herrmann JE,Morse SA,Collins MF

更新日期：1974-07-01 00:00:00

abstract：:High-density oligonucleotide microarrays are widely used to study gene expression in cells exposed to a variety of pathogens. This study addressed the global genome-wide transcriptional activation of genes in hosts infected in vivo, which result in radically different clinical outcomes. We present an analysis of the g...

journal_title：Infection and immunity

authors： Schaecher K,Kumar S,Yadava A,Vahey M,Ockenhouse CF

更新日期：2005-09-01 00:00:00

abstract：:Purified R-28 antigen from an M-protein-poor, R-antigen-rich strain of group A Streptococcus was prepared by sequential treatment of an acid extract of whole cells with ammonium sulfate fractionation and hydroxylapatite (HA) column chromatography. Purified R-28 antigen was eluted only with 0.10 M sodium phosphate, pH ...

journal_title：Infection and immunity

authors： Johnson RH

更新日期：1975-10-01 00:00:00

abstract：:Infection of epithelial cells by two biovars of Chlamydia trachomatis results in the tyrosine phosphorylation of several host proteins. The most prominent change in host protein tyrosine phosphorylation involves a complex of proteins with molecular masses of 75 to 85 kDa (pp75/85) and 100 kDa (pp100). The C. trachomat...

journal_title：Infection and immunity

authors： Fawaz FS,van Ooij C,Homola E,Mutka SC,Engel JN

更新日期：1997-12-01 00:00:00

abstract：:Murine cytomegalovirus pools from various in vitro and in vivo sources were compared for virulence in suckling mice in an effort to identify the conditions which were necessary for the production of virulent and attenuated viruses. Virus passaged in tracheal ring and salivary gland organ cultures, where virus is produ...

journal_title：Infection and immunity

authors： Selgrade MK,Nedrud JG,Collier AM,Gardner DE

更新日期：1981-09-01 00:00:00

abstract：:Rabbits are not usually susceptible to intestinal Shigella infection without extensive pretreatment, including starvation and administration of antimicrobial, antimotility, and toxic agents (carbon tetrachloride). Most animals infected this way die rapidly and do not always develop colonic lesions and signs of dysente...

journal_title：Infection and immunity

authors： Rabbani GH,Albert MJ,Rahman H,Islam M,Mahalanabis D,Kabir I,Alam K,Ansaruzzaman M

更新日期：1995-11-01 00:00:00

abstract：:The intracellular pathogen Listeria monocytogenes replicates mainly in resting macrophages and hepatocytes residing in infected tissues. Both innate and acquired resistance strongly depend on activation of listericidal capacities of macrophages by gamma interferon (IFN-gamma) produced by natural killer cells and T lym...

journal_title：Infection and immunity

authors： Szalay G,Hess J,Kaufmann SH

更新日期：1995-08-01 00:00:00

abstract：:Antigen-specific T-cell responses and histopathological changes were studied in mice experimentally inoculated with Borrelia burgdorferi B31. Inbred mice with different H-2 haplotypes and/or different genetic backgrounds were inoculated with B. burgdorferi organisms and tested for antigen-specific T-cell responses in ...

journal_title：Infection and immunity

authors： Schaible UE,Kramer MD,Justus CW,Museteanu C,Simon MM

更新日期：1989-01-01 00:00:00

abstract：:Hamster respiratory epithelial cells were cultured in a monolayer format, and 20% of the cells were ciliated. Mycoplasma pneumoniae attached to the epithelial cells in a neuraminidase-specific fashion and induced ciliostasis and cytonecrosis. ...

journal_title：Infection and immunity

authors： Gabridge MG,Gunderson H,Schaeffer SL,Barden-Stahl YD

更新日期：1978-07-01 00:00:00