Intestinal Epithelial Ecto-5'-Nucleotidase (CD73) Regulates Intestinal Colonization and Infection by Nontyphoidal Salmonella.

abstract：:With large amounts of parasite gene sequence available, additional bioinformatic tools to screen these sequences for identifying genes encoding antigens are needed. Proteins containing tandem repeat (TR) domains are often B-cell antigens, and antibody responses toward TR domains of the proteins are dominant in human i...

journal_title：Infection and immunity

authors： Goto Y,Coler RN,Reed SG

更新日期：2007-02-01 00:00:00

abstract：:Following intranasal inoculation, Vibrio cholerae KFV101 (DeltactxAB DeltahapA DeltahlyA DeltartxA) colonizes and stimulates tumor necrosis factor alpha and interleukin 1beta (IL-1beta) in mice, similar to what occurs with isogenic strain P4 (DeltactxAB), but is less virulent and stimulates reduced levels of IL-6, dem...

journal_title：Infection and immunity

authors： Haines GK 3rd,Sayed BA,Rohrer MS,Olivier V,Satchell KJ

更新日期：2005-09-01 00:00:00

abstract：:The hemolytic activity of the thermostable direct hemolysin produced by Vibrio parahaemolyticus was inhibited by a ganglioside mixture. The ganglioside component which inhibited the hemolysin was not FM1 ganglioside. ...

journal_title：Infection and immunity

authors： Takeda R,Honda T,Sakural J,Otomo N

更新日期：1975-10-01 00:00:00

abstract：:Staphylococcus aureus is a pathogen that causes significant morbidity and mortality. Nasal carriage is a major source of transmission and of endogenous infection. Persistent carriage is detected in ∼30% of healthy individuals. While Th17 cells have been shown to play a role in S. aureus infection and clearance, the im...

journal_title：Infection and immunity

authors： Reiss-Mandel A,Rubin C,Zayoud M,Rahav G,Regev-Yochay G

更新日期：2018-02-20 00:00:00

abstract：:Monoclonal antibodies against 12 of the 17 IATS serotype strains of Pseudomonas aeruginosa were produced. Eighty-seven hybridoma clones were isolated, and the antibodies secreted were found to be reactive with both Formalin-fixed whole cells and purified lipopolysaccharide of homologous strains in enzyme-linked immuno...

journal_title：Infection and immunity

authors： Lam JS,MacDonald LA,Lam MY,Duchesne LG,Southam GG

更新日期：1987-05-01 00:00:00

abstract：:The effects of passive administration of neutralizing monoclonal antibodies (MAB) to respiratory syncytial virus glycoproteins (GP90 and VP70) was evaluated in cotton rats challenged with respiratory syncytial virus. Animals injected with MAB to VP70 had lower mean viral titers in lung tissues than did controls (log10...

journal_title：Infection and immunity

authors： Walsh EE,Schlesinger JJ,Brandriss MW

更新日期：1984-02-01 00:00:00

abstract：:Monoclonal antibodies to Trichomonas vaginalis were prepared by immunizing mice with a cloned isolate of T. vaginalis. Eight antibodies reacted with the same four isolates or strains but did not react with the other T. vaginalis strains or isolates tested. All eight antibodies reacted uniformly with both the body and ...

journal_title：Infection and immunity

authors： Torian BE,Connelly RJ,Stephens RS,Stibbs HH

更新日期：1984-01-01 00:00:00

abstract：:Botulinum neurotoxins (BoNTs) and tetanus toxin (TeNT) are the most potent toxins for humans and elicit unique pathologies due to their ability to traffic within motor neurons. BoNTs act locally within motor neurons to elicit flaccid paralysis, while retrograde TeNT traffics to inhibitory neurons within the central ne...

journal_title：Infection and immunity

authors： Zuverink M,Chen C,Przedpelski A,Blum FC,Barbieri JT

更新日期：2015-07-01 00:00:00

abstract：:Streptococcus suis is one of the most important pathogens affecting the swine industry and is also an emerging zoonotic agent for humans. Two-component signaling systems (TCSs) play important roles in the adaptation of pathogenic bacteria to host environments. In this study, we identified a novel TCS, named TCS09HKRR,...

journal_title：Infection and immunity

authors： Zhong X,Zhang Y,Zhu Y,Dong W,Ma J,Pan Z,Yao H

更新日期：2019-08-21 00:00:00

abstract：:A major obstacle to studying the functions of particular gene products in the mouse-tick infectious cycle of Borrelia burgdorferi has been an inability to knock out genes in pathogenic strains. Here, we investigated conditions for site-directed mutagenesis in B31 MI, the low-passage-number, infectious B. burgdorferi s...

journal_title：Infection and immunity

authors： Elias AF,Stewart PE,Grimm D,Caimano MJ,Eggers CH,Tilly K,Bono JL,Akins DR,Radolf JD,Schwan TG,Rosa P

更新日期：2002-04-01 00:00:00

abstract：:Schistosoma mansoni-infected wild-type (WT) mice develop a Th2 response and chronic disease. In contrast, infected interleukin-4 double-deficient (IL-4(-/-)) mice develop a Th1-like response and an acute, lethal syndrome. Disease severity in these animals correlates with excessive and prolonged production of nitric ox...

journal_title：Infection and immunity

authors： Patton EA,La Flamme AC,Pedras-Vasoncelos JA,Pearce EJ

更新日期：2002-01-01 00:00:00

abstract：:The extracellular cysteine protease from Streptococcus pyogenes is a virulence factor that plays a significant role in host-pathogen interaction. Streptococcal protease is expressed as an inactive 40-kDa precursor that is autocatalytically converted into a 28-kDa mature (active) enzyme. Replacement of the single cyste...

journal_title：Infection and immunity

authors： Matsuka YV,Pillai S,Gubba S,Musser JM,Olmsted SB

更新日期：1999-09-01 00:00:00

abstract：:Quorum-sensing systems are critical regulators of the expression of virulence factors of various organisms, including Pseudomonas aeruginosa. Las and Rhl are two major quorum-sensing components, and they are regulated by their corresponding autoinducers, N-3-oxododecanoyl homoserine lactone (3-oxo-C(12)-HSL) and N-but...

journal_title：Infection and immunity

authors： Tateda K,Ishii Y,Horikawa M,Matsumoto T,Miyairi S,Pechere JC,Standiford TJ,Ishiguro M,Yamaguchi K

更新日期：2003-10-01 00:00:00

abstract：:Killing of Salmonella minnesota and Salmonella typhimurium S and R strains in serum of nonimmune humans and guinea pigs was drastically reduced in the selective absence of C1q, C1r, Ca2+, C4, or C2, the components of the classical complement pathway. Binding of C1 and C1q to the S form and six different core-deficient...

journal_title：Infection and immunity

authors： Clas F,Loos M

更新日期：1982-09-01 00:00:00

abstract：:Group B streptococci (GBS) are the major cause of neonatal pneumonia, sepsis, and meningitis. Steps considered to be important in the pathogenesis of this infection include colonization of the rectum and vagina of the mother, aspiration of GBS into the fetal lung during or just prior to delivery, and invasion of GBS i...

journal_title：Infection and immunity

authors： Tamura GS,Kuypers JM,Smith S,Raff H,Rubens CE

更新日期：1994-06-01 00:00:00

abstract：:In order to approximate and adhere to mucosal epithelial cells, Candida must traverse the overlying mucus layer. Interactions of Candida species with mucin and human buccal epithelial cells (BECs) were thus investigated in vitro. Binding of the Candida species to purified small intestinal mucin showed a close correlat...

journal_title：Infection and immunity

authors： de Repentigny L,Aumont F,Bernard K,Belhumeur P

更新日期：2000-06-01 00:00:00

abstract：:The mig gene of Streptococcus dysgalactiae, a major bovine mastitis pathogen, encodes two plasma protein-binding receptors, alpha2-macroglobulin (alpha2-M) and immunoglobulin G (IgG). In this study, the mig gene from one S. dysgalactiae isolate was cloned and expressed in Escherichia coli. The IgG receptor region enco...

journal_title：Infection and immunity

authors： Song XM,Perez-Casal J,Bolton A,Potter AA

更新日期：2001-10-01 00:00:00

abstract：:Immune responses in the guinea pig model are understudied because of a lack of commercial reagents. We have developed a custom-made guinea pig oligonucleotide microarray (81 spots) and have examined the gene expression profile of splenocytes restimulated in vitro from Mycobacterium bovis BCG-vaccinated and naive anima...

journal_title：Infection and immunity

authors： Tree JA,Elmore MJ,Javed S,Williams A,Marsh PD

更新日期：2006-02-01 00:00:00

abstract：:Nitration of protein A with tetranitromethane incompletely blocks its Fc-binding ability for immunoglobulin G when measured by more sensitive methods of immunoprecipitation and when tested in the enzyme-linked immunosorbent assay. In addition, binding of protein A and blockage by nitration is heterogeneous and depends...

journal_title：Infection and immunity

authors： Sloan GJ,Butler JE

更新日期：1978-08-01 00:00:00

abstract：:Minicells are small, anucleate cells resulting from aberrant cell divisions at the polar ends of bacilli. We have isolated minicell-producing mutant strains of Shigella flexneri 2a (MC-I) and Shigella dysenteriae 1 (MC-V) after mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine. Microscopically, broth cultures of M...

journal_title：Infection and immunity

authors： Gemski P,Griffin DE

更新日期：1980-10-01 00:00:00

abstract：:Immunofluorescence microscopy demonstrated that laminin bound to the surface of Penicillium marneffei conidia. Attachment of P. marneffei conidia in an adherence assay was inhibited by soluble laminin and anti-laminin antibody. N-Acetylneuraminic acid abolished adherence, indicating an interaction mediated by a sialic...

journal_title：Infection and immunity

authors： Hamilton AJ,Jeavons L,Youngchim S,Vanittanakom N,Hay RJ

更新日期：1998-12-01 00:00:00

abstract：:The flavivirus dengue and the arenavirus Junin are both associated with a hemorrhagic shock syndrome in man. We have demonstrated the replication of these viruses in vitro in both rabbit and human endothelial cells by viral titers and immunofluorescent antibody studies. Rabbit endothelium established in continuous cul...

journal_title：Infection and immunity

authors： Andrews BS,Theofilopoulos AN,Peters CJ,Loskutoff DJ,Brandt WE,Dixon FJ

更新日期：1978-06-01 00:00:00

abstract：:Differences in molecular composition of lipopolysaccharides (LPS) between serum-sensitive (S) clinical isolates of Escherichia coli and serum-resistant (R) clones derived by serial passage in serum were demonstrated to determine sensitivity or resistance to killing by normal human serum (NHS). LPS from R clones had a ...

journal_title：Infection and immunity

authors： Porat R,Johns MA,McCabe WR

更新日期：1987-02-01 00:00:00

abstract：:Growing Streptococcus gordonii Spp+ phase variants, which have normal levels of glucosyltransferase (GTF) activity, use sucrose to promote their accumulation on surfaces by forming a cohesive bacterium-insoluble glucan polymer mass (BPM). Spp- phase variants, which have lower levels of GTF activity, do not form BPMs a...

journal_title：Infection and immunity

authors： Vickerman MM,Jones GW

更新日期：1992-10-01 00:00:00

abstract：:When tested for their activity in suppressing the acquisition of immunity during acute Besnoitia infection of hamsters, antilymphocyte serum (ALS), aminopterin, cyclophosphamide, cortisol, and whole-body irradiation were the most active agents and effectively blocked the development of immunity during 4 to 12 days of ...

journal_title：Infection and immunity

authors： Wilson HR,Frenkel JK

更新日期：1971-06-01 00:00:00

abstract：:Trichinella spiralis creates a unique intracellular habitat in striated muscle. We report that a proteoglycan, syndecan-1, is induced early in infection yet is not essential for habitat development and exerts a modest influence on the immune response. This report is the first to address the requirement for a specific ...

journal_title：Infection and immunity

authors： Beiting DP,Park PW,Appleton JA

更新日期：2006-03-01 00:00:00

abstract：:Group B streptococci (GBS) adhere to surface receptors present on epithelial cells; these receptors include fibronectin and laminin. To identify other possible receptors, plasma membranes from A549 cells, a respiratory tract epithelial cell line, were prepared. These plasma membranes were tested in a protein blot anal...

journal_title：Infection and immunity

authors： Tamura GS,Nittayajarn A

更新日期：2000-04-01 00:00:00

abstract：:In this study we demonstrate the capability of Chlamydia trachomatis to infect cultured human mesothelial cell (MC) monolayers and to induce the production of the proinflammatory cytokines interleukin 1beta (IL-1beta) and IL-8. Seventy-two hours after initial infection, both the procoagulant activity of MC and the act...

journal_title：Infection and immunity

authors： van Westreenen M,Pronk A,Diepersloot RJ,de Groot PG,Leguit P

更新日期：1998-05-01 00:00:00

abstract：:We have previously shown that chinchillas infected with a multiply passaged laboratory strain of influenza A/NWS/33 (H1N1) develop negative middle-ear pressure; polymorphonuclear leukocyte oxidative, bactericidal, and chemotactic dysfunction; and increased susceptibility to pneumococcal otitis media. Because influenza...

journal_title：Infection and immunity

authors： Giebink GS,Wright PF

更新日期：1983-09-01 00:00:00

abstract：:We developed a porcine dermal explant model to determine the extent to which Staphylococcus aureus biofilm communities deplete oxygen, change pH, and produce damage in underlying tissue. Microelectrode measurements demonstrated that dissolved oxygen (DO) in biofilm-free dermal tissue was 4.45 ± 1.17 mg/liter, while DO...

journal_title：Infection and immunity

authors： Lone AG,Atci E,Renslow R,Beyenal H,Noh S,Fransson B,Abu-Lail N,Park JJ,Gang DR,Call DR

更新日期：2015-06-01 00:00:00