Synthesis of syndecan-1 by skeletal muscle cells is an early response to infection with Trichinella spiralis but is not essential for nurse cell development.

abstract：:It has been proposed that a multivalent malaria vaccine is necessary to mimic the naturally acquired resistance to this disease observed in humans. A major experimental challenge is to identify the optimal components to be used in such a multivalent vaccine. Expression library immunization (ELI) is a method for screen...

journal_title：Infection and immunity

authors： Rainczuk A,Scorza T,Smooker PM,Spithill TW

更新日期：2003-08-01 00:00:00

abstract：:Interaction of bacteria with mucosal surfaces can modulate the production of proinflammatory cytokines and adhesion molecules produced by epithelial cells. Previously, we showed that expression of interleukin-8 (IL-8) and intercellular adhesion molecule 1 (ICAM-1) by gingival epithelial cells increases following inter...

journal_title：Infection and immunity

authors： Huang GT,Kim D,Lee JK,Kuramitsu HK,Haake SK

更新日期：2001-03-01 00:00:00

abstract：:Immune and pathologic responses were measured for 20 weeks after infection of mice with Brucella abortus 19, RB51, or 2308. Live bacteria and bacterial antigens of 19 and RB51 persisted in spleens for 10 and 4 weeks after infection, respectively, whereas 2308 bacteria and bacterial antigens persisted for at least 20 w...

journal_title：Infection and immunity

authors： Stevens MG,Olsen SC,Pugh GW Jr,Palmer MV

更新日期：1994-08-01 00:00:00

abstract：:Pertussis toxin (PT), a virulence factor secreted by Bordetella pertussis, contributes to respiratory tract infection and disease caused by this pathogen. By comparing a wild-type (WT) B. pertussis strain to a mutant strain with an in-frame deletion of the ptx genes encoding PT (DeltaPT), we recently found that the la...

journal_title：Infection and immunity

authors： Carbonetti NH,Artamonova GV,Andreasen C,Dudley E,Mays RM,Worthington ZE

更新日期：2004-06-01 00:00:00

abstract：:A hallmark of Bartonella henselae is persistent bacteremia in cats despite the presence of a vigorous host immune response. To understand better the long-term survival of B. henselae in cats, we examined the feline humoral immune response to B. henselae outer membrane (OM) proteins in naturally and experimentally infe...

journal_title：Infection and immunity

authors： Chenoweth MR,Greene CE,Krause DC,Gherardini FC

更新日期：2004-06-01 00:00:00

abstract：:Nitration of protein A with tetranitromethane incompletely blocks its Fc-binding ability for immunoglobulin G when measured by more sensitive methods of immunoprecipitation and when tested in the enzyme-linked immunosorbent assay. In addition, binding of protein A and blockage by nitration is heterogeneous and depends...

journal_title：Infection and immunity

authors： Sloan GJ,Butler JE

更新日期：1978-08-01 00:00:00

abstract：:In this study, the role of the hepatobiliary system in the early pathogenesis of Salmonella enteritidis infection was investigated in a rat model. Intravenous (i.v.) challenge with lipopolysaccharide (LPS) has previously been shown to enhance the translocation of normal gut flora. We first confirmed that LPS can simil...

journal_title：Infection and immunity

authors： Islam AF,Moss ND,Dai Y,Smith MS,Collins AM,Jackson GD

更新日期：2000-01-01 00:00:00

abstract：:We purified three proline-rich antimicrobial peptides from elastase-treated extracts of sheep and goat leukocytes and subjected two of them, OaBac5alpha and ChBac5, to detailed analysis. OaBac5alpha and ChBac5 were homologous to each other and to bovine Bac5. Both exhibited potent, broad-spectrum antimicrobial activit...

journal_title：Infection and immunity

authors： Shamova O,Brogden KA,Zhao C,Nguyen T,Kokryakov VN,Lehrer RI

更新日期：1999-08-01 00:00:00

abstract：:Cholera toxin (CT) is a potent adjuvant for mucosal vaccination; however, its mechanism of action has not been clarified completely. It is well established that peripheral monocytes differentiate into dendritic cells (DCs) both in vitro and in vivo and that monocytes are the in vivo precursors of mucosal CD103(-) proi...

journal_title：Infection and immunity

authors： Veglia F,Sciaraffia E,Riccomi A,Pinto D,Negri DR,De Magistris MT,Vendetti S

更新日期：2011-03-01 00:00:00

abstract：:T cell-independent antibody responses develop rapidly, within 3 to 4 days, and are critical for preventing blood-borne pathogens from evolving into life-threatening infections. The interaction of BAFF, also known as BLyS, with its receptors BAFFR and TACI on B cells is critical for B cell homeostasis and function. Usi...

journal_title：Infection and immunity

authors： Dickinson GS,Sun G,Bram RJ,Alugupalli KR

更新日期：2014-01-01 00:00:00

abstract：:In vivo expression of pili by Escherichia coli in the urine of 41 adults with lower urinary tract infections was analyzed by immunostaining with polyclonal antiserum to type 1 and P pili. Type 1 pili were detected in 31 of 41 urine specimens, while P pili were detected in 6 of 18 specimens. The piliation status of bac...

journal_title：Infection and immunity

authors： Kisielius PV,Schwan WR,Amundsen SK,Duncan JL,Schaeffer AJ

更新日期：1989-06-01 00:00:00

abstract：:Arthritis is a frequent and major complication of infection with Borrelia burgdorferi sensu stricto. The antigens responsible for the induction of arthritis are unknown. Here we provide direct evidence that a major surface protein, outer surface protein A (OspA), can induce arthritis. Hamsters were vaccinated with 30,...

journal_title：Infection and immunity

authors： Croke CL,Munson EL,Lovrich SD,Christopherson JA,Remington MC,England DM,Callister SM,Schell RF

更新日期：2000-02-01 00:00:00

abstract：:The effect of route of administration, dosage, and number of boosts employed during immunization with the polymyxin-release form of Escherichia coli heat-labile (LT) enterotoxin on the degree and duration of protection afforded was evaluated in rats which were challenged by the ligated loop technique. Increasing the b...

journal_title：Infection and immunity

authors： Klipstein FA,Engert RF

更新日期：1980-01-01 00:00:00

abstract：:The immunodominant proteins and glycoproteins of Borrelia burgdorferi were analyzed by one-dimensional (1D) and 2D gel electrophoresis. More than 100 polypeptide species could be detected on silver-stained 2D gels. Separation of sonic extracts of the organism by differential centrifugation (100,000 X g) revealed sever...

journal_title：Infection and immunity

authors： Luft BJ,Jiang W,Munoz P,Dattwyler RJ,Gorevic PD

更新日期：1989-11-01 00:00:00

abstract：:Salivary gland lysates of the sand fly Lutzomyia longipalpis markedly enhance the course of infection with Leishmania major in mice. Here we examine various parameters of this phenomenon. The exacerbative effect of L. longipalpis salivary gland lysates occurred in five different mouse strains; however, the character o...

journal_title：Infection and immunity

authors： Theodos CM,Ribeiro JM,Titus RG

更新日期：1991-05-01 00:00:00

abstract：:The complete nucleotide sequence of a 612-base-pair DNA fragment containing the gene for the major fimbrial subunit of CS3 of enterotoxigenic Escherichia coli is presented. A possible promoter region, a ribosome-binding site, and two potential signal peptidase cleavage sites are indicated. Unlike the best-studied fimb...

journal_title：Infection and immunity

authors： Boylan M,Smyth CJ,Scott JR

更新日期：1988-12-01 00:00:00

abstract：:Klebsiella pneumoniae strains typically express both smooth lipopolysaccharide (LPS) with O antigen molecules and capsule polysaccharide (K antigen) on the surface. A single mutation in a gene that codes for a UDP galacturonate 4-epimerase (uge) renders a strain with the O-:K- phenotype (lack of capsule and LPS withou...

journal_title：Infection and immunity

authors： Regué M,Hita B,Piqué N,Izquierdo L,Merino S,Fresno S,Benedí VJ,Tomás JM

更新日期：2004-01-01 00:00:00

abstract：:Epitope mapping of outer surface protein C (OspC) by using sera from patients with neuroborreliosis led to the identification of one single major immunodominant epitope within the C-terminal 10 amino acid residues. Peptide binding studies and alanine replacement scanning of the C-terminal decapeptide, PVVAESPKKP, reve...

journal_title：Infection and immunity

authors： Mathiesen MJ,Holm A,Christiansen M,Blom J,Hansen K,Ostergaard S,Theisen M

更新日期：1998-09-01 00:00:00

abstract：:Chronic Helicobacter pylori infection is associated with mucosal inflammation. The aim of the present study was to assess human neutrophil and monocyte activation by H. pylori strains obtained from patients with different clinical presentations. Bacterial sonicates from 12 strains were used to stimulate phagocyte upre...

journal_title：Infection and immunity

authors： Hansen PS,Go MF,Varming K,Andersen LP,Genta RM,Graham DY,Nielsen H

更新日期：1999-06-01 00:00:00

abstract：:Recent efforts to develop a vaccine against the diarrheal disease cholera have focused on the use of live attenuated strains of the causative organism, Vibrio cholerae. The Ogawa lipopolysaccharide phenotype is expressed by many epidemic strains, and motility defects reduce the risk of reactive diarrhea in vaccine rec...

journal_title：Infection and immunity

authors： Chiang SL,Mekalanos JJ

更新日期：2000-11-01 00:00:00

abstract：:Neisseria gonorrhoeae is an obligate human pathogen that causes the common sexually transmitted infection gonorrhea. Gonococcal infections cause significant morbidity, particularly among women, as the organism ascends to the upper reproductive tract, resulting in pelvic inflammatory disease, ectopic pregnancy, and inf...

journal_title：Infection and immunity

authors： Hollander A,Mercante AD,Shafer WM,Cornelissen CN

更新日期：2011-12-01 00:00:00

abstract：:Cells of several strains of Streptococcus gordonii attached in much higher numbers to experimental pellicles formed from samples of submandibular or parotid saliva on hydroxyapatite (HA) beads than to buffer controls. The nature of the salivary components responsible were investigated by preparing experimental pellicl...

journal_title：Infection and immunity

authors： Gibbons RJ,Hay DI,Schlesinger DH

更新日期：1991-09-01 00:00:00

abstract：:Colonization of the large bowel of healthy infants by Clostridium difficile was studied. Feces were collected from five breast-fed aand five formula-fed infants throughout the first year of life, and levels of C. difficile were quantitated. Three breast-fed and five formula-fed infants were colonized for periods of be...

journal_title：Infection and immunity

authors： Stark PL,Lee A,Parsonage BD

更新日期：1982-03-01 00:00:00

abstract：:Porphyromonas gingivalis is a major etiologic agent of periodontitis, a chronic inflammatory disease that ultimately results in the loss of the supporting tissues of the teeth. Previous work has demonstrated the usefulness of avirulent Salmonella enterica serovar Typhimurium strains as antigen delivery systems for pro...

journal_title：Infection and immunity

authors： Kozarov E,Miyashita N,Burks J,Cerveny K,Brown TA,McArthur WP,Progulske-Fox A

更新日期：2000-02-01 00:00:00

abstract：:A progressive increase in infections with multiresistant Enterococcus faecium has been reported, especially in cancer patients and neutropenic patients. Despite its increasing importance as a nosocomial pathogen, knowledge of the pathogenesis of E. faecium infections is highly limited. In this study, we investigated t...

journal_title：Infection and immunity

authors： Leendertse M,Willems RJ,Giebelen IA,Roelofs JJ,Bonten MJ,van der Poll T

更新日期：2009-01-01 00:00:00

abstract：:Pseudomonas aeruginosa is a gram-negative bacillus that is a major cause of morbidity and mortality in immunosuppressed patients, burn patients, and patients with cystic fibrosis. Although immunity to these bacteria has been associated with serum antibody, more recent evidence suggests that T-cell-mediated immunity ma...

journal_title：Infection and immunity

authors： Porwoll JM,Gebel HM,Rodey GE,Markham RB

更新日期：1983-05-01 00:00:00

abstract：:Mice with disrupted beta 2-microglobulin (beta 2m-/-), I-A (class II-/-), or CD4 (CD4-/-) genes were examined for their capacity to resolve Chlamydia trachomatis genital tract infection. C57BL/6 and beta 2m-/- mice resolved infection similarly and were culture negative by 4 to 5 weeks following infection. Conversely, ...

journal_title：Infection and immunity

authors： Morrison RP,Feilzer K,Tumas DB

更新日期：1995-12-01 00:00:00

abstract：:Strains of type III group B streptococci isolated from patients with neonatal sepsis are generally resistant to complement-mediated phagocytic killing in the absence of specific antibody. It has been suggested that the resistance of type III group B streptococci to phagocytosis results from inhibition of alternative-c...

journal_title：Infection and immunity

authors： Marques MB,Kasper DL,Pangburn MK,Wessels MR

更新日期：1992-10-01 00:00:00

abstract：:Shiga toxigenic Escherichia coli (STEC) strains are a diverse group of organisms capable of causing severe gastrointestinal disease in humans. Within the STEC family, eae-positive STEC strains, particularly those belonging to serogroups O157 and O111, appear to have greater virulence for humans. However, in spite of b...

journal_title：Infection and immunity

authors： Paton AW,Paton JC

更新日期：1999-11-01 00:00:00

abstract：:Two distinct and complementary pathways, one mediated by perforin and the other dependent upon CD95 (Fas), effect cell-mediated cytotoxicity. We examined the relative roles of these pathways in host defenses against the intracellular bacterial pathogen Listeria monocytogenes by using murine listeriosis as a model syst...

journal_title：Infection and immunity

authors： Jensen ER,Glass AA,Clark WR,Wing EJ,Miller JF,Gregory SH

更新日期：1998-09-01 00:00:00