Biochemical and immunological characterization of the surface proteins of Borrelia burgdorferi.

abstract：:Transcription of the gene encoding the antiphagocytic M protein (emm) of the group A streptococci has been shown to be regulated by CO2 (M. G. Caparon, R. T. Geist, J. Perez-Casal, and J. R. Scott, J. Bacteriol. 174:5693-5701, 1992). We tested the influence of additional environmental growth conditions on emm expressi...

journal_title：Infection and immunity

authors： McIver KS,Heath AS,Scott JR

更新日期：1995-11-01 00:00:00

abstract：:Escherichia coli is a major cause of enteric/diarrheal diseases, urinary tract infections, and sepsis. E. coli K1 is the leading gram-negative organism causing neonatal meningitis, but the microbial basis of E. coli K1 meningitis is incompletely understood. Here we employed comparative genomic hybridization to investi...

journal_title：Infection and immunity

authors： Yao Y,Xie Y,Kim KS

更新日期：2006-04-01 00:00:00

abstract：:We have developed experimental murine Campylobacter infection models which demonstrate efficient establishment and reproducible, high-level colonization. Following oral inoculation, wild-type C3H mice with normal enteric flora were colonized inconsistently and inefficiently by C. jejuni strain 81-176. However, C3H mic...

journal_title：Infection and immunity

authors： Chang C,Miller JF

更新日期：2006-09-01 00:00:00

abstract：:The urease gene of Staphylococcus saprophyticus CCM883 was cloned and expressed in Staphylococcus carnosus TM300. In vitro translation of the cloned DNA sequences revealed six polypeptides (of 70, 47, 29, 27, 20, and 17 kilodaltons) that were associated with enzyme activity. Introduction of the cloned genes into a ure...

journal_title：Infection and immunity

authors： Gatermann S,Marre R

更新日期：1989-10-01 00:00:00

abstract：:The attachment and invasion of chicken ovarian granulosa cells by Salmonella enteritidis was examined in vitro. The attachment was inhibited by preincubation of granulosa cells with anti-chicken fibronectin antibody (approximately 70% reduction in attachment) or preincubation with a 14-kDa fimbrial protein isolated fr...

journal_title：Infection and immunity

authors： Thiagarajan D,Saeed M,Turek J,Asem E

更新日期：1996-12-01 00:00:00

abstract：:Experimental Helicobacter pylori infection was studied in Mongolian gerbils with fresh human isolates that carry or do not carry cagA (cagA-positive or cagA-negative, respectively), multiply passaged laboratory strains, wild-type strain G1.1, or isogenic ureA, cagA, or vacA mutants of G1.1. Animals were sacrificed 1 t...

journal_title：Infection and immunity

authors： Wirth HP,Beins MH,Yang M,Tham KT,Blaser MJ

更新日期：1998-10-01 00:00:00

abstract：:Comparative studies on the virulence of two strains of Pseudomonas aeruginosa isolated from otic pus and mink pneumonic lesion, respectively, were made by means of intranasal inoculation in mink. The minimal lethal dose of the former (strain NC-5, highly virulent for mice) was 10(10), and that of the latter (strain No...

journal_title：Infection and immunity

authors： Shimizu T,Homma JY,Aoyama T,Onodera T,Noda H

更新日期：1974-07-01 00:00:00

abstract：:Hamster trachea organ cultres were shown to consume measurable amounts of oxygen when incubated in a closed micro-chamber. Several simple and complex media were evaluated, and the optimal system involved incubating 2 to 4 mg of tracheal tissue in Tyrodes balanced salt solution at 37 C for 60 min, with oxygen activity ...

journal_title：Infection and immunity

authors： Gabridge MG

更新日期：1975-09-01 00:00:00

abstract：:The antiinflammatory cytokine response during urosepsis was determined by measurement of concentrations of soluble tumor necrosis factor receptor (sTNFR) types I and II, interleukin 1 receptor antagonist (IL-1ra), soluble IL-1 receptor type II (sIL-1RII), and interleukin 10 in sera and urine of 30 patients with cultur...

journal_title：Infection and immunity

authors： Olszyna DP,Prins JM,Buis B,van Deventer SJ,Speelman P,van der Poll T

更新日期：1998-08-01 00:00:00

abstract：:Random-bred mice were immunized with a nonliving antigen prepared from mixed-blood forms of Plasmodium berghei, strain NYU-2, in combination with Corynebacterium parvum and/or living BCG. A high proportion of intravenously immunized mice survived virulent challenge, but subcutaneous vaccination was less effective. Vac...

journal_title：Infection and immunity

authors： Murphy JR,Lefford MJ

更新日期：1978-12-01 00:00:00

abstract：:B cell activating factor of the tumor necrosis factor family (BAFF) is an essential survival factor for B cells and has been shown to regulate T cell-independent (TI) IgM production. During Ehrlichia muris infection, TI IgM secretion in the spleen was BAFF dependent, and antibody-mediated BAFF neutralization led to an...

journal_title：Infection and immunity

authors： Jones DD,Jones M,DeIulio GA,Racine R,MacNamara KC,Winslow GM

更新日期：2013-12-01 00:00:00

abstract：:An escape variant of Borrelia burgdorferi, selected with a monoclonal antibody to OspB, expressed a truncated form of OspB, the result of point mutations in the ospB gene leading to a premature termination codon. A single amino acid position in the C terminus of OspB was critical for monoclonal antibody recognition. T...

journal_title：Infection and immunity

authors： Coleman JL,Rogers RC,Rosa PA,Benach JL

更新日期：1994-01-01 00:00:00

abstract：:The response of the intracellular pathogen Rhodococcus equi to H(2)O(2) treatment, a situation potentially encountered after the oxidative burst of alveolar macrophages, was analyzed. Compared to other bacteria, including Deinococcus radiodurans, R. equi showed exceptionally high resistance to this stress. A proteomic...

journal_title：Infection and immunity

authors： Benoit S,Benachour A,Taouji S,Auffray Y,Hartke A

更新日期：2002-07-01 00:00:00

abstract：:A DNA microarray containing fragments of 137 Borrelia burgdorferi B31 putative lipoprotein genes was used to examine Lyme disease spirochetes. DNA from B. burgdorferi sensu stricto B31, 297, and N40; Borrelia garinii IP90; and Borrelia afzelii P/Gau was fluorescently labeled and hybridized to the microarray, demonstra...

journal_title：Infection and immunity

authors： Liang FT,Nelson FK,Fikrig E

更新日期：2002-06-01 00:00:00

abstract：:The hemolytic and sphingomyelinase C activities of supernatants of cultures of Leptospira interrogans serovar pomona tended to copurify when isoelectric fractionation was carried out. Both activities focused primarily at pH 8.1. Considered in conjunction with other circumstantial evidence, the results led to the concl...

journal_title：Infection and immunity

authors： Bernheimer AW,Bey RF

更新日期：1986-10-01 00:00:00

abstract：:We have cloned chromosomal genes mediating the aerobactin iron transport system from the enteroinvasive strain Escherichia coli 978-77. The physical map of the region spanning the siderophore biosynthesis genes and the upstream portion of the receptor gene in strain 978-77-derived clones was identical to the correspon...

journal_title：Infection and immunity

authors： Marolda CL,Valvano MA,Crosa JH

更新日期：1991-01-01 00:00:00

abstract：:A major goal of current vaccine development is the induction of strong immune responses against protective antigens delivered by mucosal routes. One of the most promising approaches in that respect relies on the use of live recombinant vaccine carriers. In this study, Mycobacterium bovis BCG was engineered to produce ...

journal_title：Infection and immunity

authors： Kremer L,Dupré L,Riveau G,Capron A,Locht C

更新日期：1998-12-01 00:00:00

abstract：:Infection with highly pathogenic Streptococcus suis can cause septic shock, which is characterized by high levels of inflammatory cytokines and a high mortality rate. Our previous study indicated that TREM-1 (triggering receptor expressed on myeloid cells 1) was upregulated in swine spleen cells in response to S. suis...

journal_title：Infection and immunity

authors： Yang C,Chen B,Zhao J,Lin L,Han L,Pan S,Fu L,Jin M,Chen H,Zhang A

更新日期：2015-08-01 00:00:00

abstract：:It was shown in this work that the infectivity of metacyclic forms of Trypanosoma cruzi was affected upon interaction with the monoclonal antibody (10D8), which reacts with a carbohydrate epitope of the 35- and 50-kilodalton (kDa) surface glycoconjugates. The invasion of Vero cells by metacyclic forms of strains Tulah...

journal_title：Infection and immunity

authors： Yoshida N,Mortara RA,Araguth MF,Gonzalez JC,Russo M

更新日期：1989-06-01 00:00:00

abstract：:An Escherichia coli oligonucleotide microarray based on three sequenced genomes was validated for comparative genomic microarray hybridization and used to study the diversity of E. coli O157 isolates from human infections and food and animal sources. Among 26 test strains, 24 (including both Shiga toxin [Stx]-positive...

journal_title：Infection and immunity

authors： Wu G,Carter B,Mafura M,Liebana E,Woodward MJ,Anjum MF

更新日期：2008-02-01 00:00:00

abstract：:Increased resistance to infection with Brucella abortus 2308 resulted when recombinant murine gamma interferon (rMuIFN-gamma) was given to mice both before and during infection but not when given only before infection. Mice given rMuIFN-gamma had enhanced peritoneal and splenic macrophage bactericidal activity against...

journal_title：Infection and immunity

authors： Stevens MG,Pugh GW Jr,Tabatabai LB

更新日期：1992-10-01 00:00:00

abstract：:Science has always been a competitive undertaking. Despite recognition of the benefits of cooperation and team science, reduced availability of funding and jobs has made science more competitive than ever. Here we consider the benefits of competition in providing incentives to scientists and the adverse effects of com...

journal_title：Infection and immunity

authors： Fang FC,Casadevall A

更新日期：2015-04-01 00:00:00

abstract：:Fibrosis is a significant complication of intestinal disorders associated with microbial dysbiosis and pathobiont expansion, notably Crohn's disease (CD). Mechanisms that favor fibrosis are not well understood, and therapeutic strategies are limited. Here we demonstrate that colitis-susceptible Il10-deficient mice dev...

journal_title：Infection and immunity

authors： Ellermann M,Gharaibeh RZ,Fulbright L,Dogan B,Moore LN,Broberg CA,Lopez LR,Rothemich AM,Herzog JW,Rogala A,Gordon IO,Rieder F,Brouwer CR,Simpson KW,Jobin C,Sartor RB,Arthur JC

更新日期：2019-10-18 00:00:00

abstract：:The 34-kilodalton (kDa) antigen of Treponema pallidum subsp. pallidum (T. pallidum) is a pathogen-specific integral membrane protein. DNA sequence analysis of the cloned gene revealed an open reading frame encoding a primary product of 204 residues with a molecular mass of 22,087 daltons. Sequences that correspond to ...

journal_title：Infection and immunity

authors： Swancutt MA,Riley BS,Radolf JD,Norgard MV

更新日期：1989-11-01 00:00:00

abstract：:Protective immunity in mice to the infective third-stage larvae (L3) of Strongyloides stercoralis was shown to be dependent on immunoglobulin M (IgM), complement activation, and granulocytes. The objectives of the present study were to determine whether IgG was also a protective antibody isotype and to define the spec...

journal_title：Infection and immunity

authors： Ligas JA,Kerepesi LA,Galioto AM,Lustigman S,Nolan TJ,Schad GA,Abraham D

更新日期：2003-12-01 00:00:00

abstract：:Photobacterium damselae subsp. damselae causes infections and fatal disease in marine animals and in humans. Highly hemolytic strains produce damselysin (Dly) and plasmid-encoded HlyA (HlyA(pl)). These hemolysins are encoded by plasmid pPHDD1 and contribute to hemolysis and virulence for fish and mice. In this study, ...

journal_title：Infection and immunity

authors： Rivas AJ,Balado M,Lemos ML,Osorio CR

更新日期：2013-09-01 00:00:00

abstract：:Chlamydia pneumoniae is a human respiratory pathogen. Unlike the other two Chlamydia species, no species-specific antigen has been defined for C. pneumoniae. An immunoreactive clone containing a 0.8-kb fragment was isolated from a C. pneumoniae (AR-39) genomic library by using anti-C. pneumoniae rabbit immune serum. B...

journal_title：Infection and immunity

authors： Perez Melgosa M,Kuo CC,Campbell LA

更新日期：1994-03-01 00:00:00

abstract：:Archived sera (collected in 1946) from acute rheumatic fever (ARF) and untreated scarlet fever and/or pharyngitis patients were reacted with streptococcal M protein, cardiac myosin, and cardiac tropomyosin. Except for very low levels to tropomyosin, antibodies to other antigens were not elevated in the sera of ARF pat...

journal_title：Infection and immunity

authors： Jones KF,Whitehead SS,Cunningham MW,Fischetti VA

更新日期：2000-12-01 00:00:00

abstract：:Porphyromonas gingivalis, a periodontopathic bacterium, is known to invade oral epithelial cells in periodontal lesions, although the mechanism is unclear. In the present study, goat polyclonal anti-intercellular adhesion molecule 1 (anti-ICAM-1) antibody inhibited the invasion of P. gingivalis into KB cells (human or...

journal_title：Infection and immunity

authors： Tamai R,Asai Y,Ogawa T

更新日期：2005-10-01 00:00:00

abstract：:When immunocompetent mice are inoculated with Borrelia burgdorferi, they develop acute arthritis and carditis that undergo spontaneous regression despite the persistence of infection. Specific T- and/or B-cell immunity appears to be necessary for resolution of disease manifestations. Humoral immune responses to B. bur...

journal_title：Infection and immunity

authors： Bockenstedt LK,Barthold S,Deponte K,Marcantonio N,Kantor FS

更新日期：1993-05-01 00:00:00