Genomic comparison of Escherichia coli K1 strains isolated from the cerebrospinal fluid of patients with meningitis.

abstract：:Four monoclonal antibodies (MAbs) were produced by immunizing mice with a disrupted yeast cell homogenate of Histoplasma capsulatum. MAbs 1 and 2 reacted only with the yeast cell antigens of H. capsulatum and Blastomyces dermatitidis, whereas MAbs 3 and 4 showed broader cross-reactivity. MAb 3 cross-reacted with B. de...

journal_title：Infection and immunity

authors： Kamel SM,Wheat LJ,Garten ML,Bartlett MS,Tansey MR,Tewari RP

更新日期：1989-03-01 00:00:00

abstract：:Strain differences have been postulated to explain the observation that group B Streptococcus type III (GBS III) late-onset disease occurs in only a fraction of colonized infants. To determine the distribution of type-specific polysaccharide antigen (Ag) in GBS III, Ag was measured by rocket immunoelectrophoresis in b...

journal_title：Infection and immunity

authors： Klegerman ME,Boyer KM,Papierniak CK,Levine L,Gotoff SP

更新日期：1984-04-01 00:00:00

abstract：:The type III secretion system (T3SS) encoded by the Salmonella pathogenicity island 2 (SPI2) has a central role in systemic infections by Salmonella enterica and for the intracellular phenotype. Intracellular S. enterica uses the SPI2-encoded T3SS to translocate a set of effector proteins into the host cell, which mod...

journal_title：Infection and immunity

authors： Hansen-Wester I,Chakravortty D,Hensel M

更新日期：2004-05-01 00:00:00

abstract：:An inactivated oral enterotoxigenic Escherichia coli (ETEC) vaccine against ETEC diarrhea was given to 25 adult Swedish volunteers. The vaccine consisted of formalin-killed E. coli bacteria expressing the most common colonization factor antigens (CFAs), i.e., CFA/I, -II, and -IV, and recombinantly produced cholera B s...

journal_title：Infection and immunity

authors： Ahrén C,Jertborn M,Svennerholm AM

更新日期：1998-07-01 00:00:00

abstract：:The influences of Neisseria gonorrhoeae protein IB content and bilayer composition of liposomes and protein content of iscoms on immunogenicity were investigated. Changes in the protein content of liposomes did not influence the immunoglobulin G response, whereas the response was lowered when the amount of protein in ...

journal_title：Infection and immunity

authors： Kersten GF,van de Put AM,Teerlink T,Beuvery EC,Crommelin DJ

更新日期：1988-06-01 00:00:00

abstract：:The role of type 1 pili in promoting bladder colonization was examined by constructing two mutant strains of a clinical Escherichia coli isolate. One mutant was isogenic to the parental strain save for a lesion in a gene required for pilus receptor binding; the other mutant was isogenic save for a lesion in the gene e...

journal_title：Infection and immunity

authors： Keith BR,Maurer L,Spears PA,Orndorff PE

更新日期：1986-09-01 00:00:00

abstract：:A major ceramide monohexoside (CMH) was purified from lipidic extracts of Cryptococcus neoformans. This molecule was analyzed by high-performance thin-layer chromatography (HPTLC), gas chromatography coupled with mass spectrometry, and fast atom bombardment-mass spectrometry. The cryptococcal CMH is a beta-glucosylcer...

journal_title：Infection and immunity

authors： Rodrigues ML,Travassos LR,Miranda KR,Franzen AJ,Rozental S,de Souza W,Alviano CS,Barreto-Bergter E

更新日期：2000-12-01 00:00:00

abstract：:The mucosal and systemic immune responses after primary and booster immunizations with two attenuated live oral vaccine strains derived from a noninvasive (Vibrio cholerae) and an invasive (Salmonella typhi) enteric pathogen were comparatively evaluated. Vaccination with S. typhi Ty21a elicited antibody-secreting cell...

journal_title：Infection and immunity

authors： Viret JF,Favre D,Wegmüller B,Herzog C,Que JU,Cryz SJ Jr,Lang AB

更新日期：1999-07-01 00:00:00

abstract：:Pathogenic members of the Yersinia genus require the translocator protein LcrV for proper function of the type III secretion apparatus, which is crucial for virulence. LcrV has also been reported to play an independent immunosuppressive role via the induction of interleukin-10 (IL-10) through stimulation of Toll-like ...

journal_title：Infection and immunity

authors： Pouliot K,Pan N,Wang S,Lu S,Lien E,Goguen JD

更新日期：2007-07-01 00:00:00

abstract：:The serum antibody response and four different cellular immune responses (cytotoxic T cells, delayed-type hypersensitivity T cells, natural killer cells, and cytotoxic macrophage levels) induced in CBA/H mice were measured at different times after intranasal inoculation of a cold-adapted (ca) variant of influenza A vi...

journal_title：Infection and immunity

authors： Mak NK,Zhang YH,Ada GL,Tannock GA

更新日期：1982-10-01 00:00:00

abstract：:Treatment of Rickettsia prowazekii-infected L929 cells with gamma interferon (IFN-gamma) immediately after infection altered the lipid metabolism of the host cells as determined by measurement of phospholipid hydrolysis and oleic acid incorporation into phospholipids and neutral lipids. At 48 h postinfection, there wa...

journal_title：Infection and immunity

authors： Winkler HH,Day L,Daugherty R,Turco J

更新日期：1993-08-01 00:00:00

abstract：:The purpose of this study was to determine the effects of human monocytes, macrophages, and polymorphonuclear neutrophils (PMN) on the fungal pathogen Blastomyces dermatitidis in vitro. Peripheral blood monocyte monolayers significantly inhibited the replication of a virulent strain (V) and an avirulent strain (AV) of...

journal_title：Infection and immunity

authors： Brummer E,Stevens DA

更新日期：1982-04-01 00:00:00

abstract：:Salmonella enterica serovar Paratyphi A O-specific polysaccharide (O-SP) was activated with 1-cyano-4-dimethylaminopyridinium tetrafluoroborate (CDAP) and bound to tetanus toxoid (TT) with adipic acid dihydrazide as a linker (SPA-TT(1)) or directly (SPA-TT(2)). In mice, these two conjugates elicited high levels of imm...

journal_title：Infection and immunity

authors： Konadu EY,Lin FY,Hó VA,Thuy NT,Van Bay P,Thanh TC,Khiem HB,Trach DD,Karpas AB,Li J,Bryla DA,Robbins JB,Szu SC

更新日期：2000-03-01 00:00:00

abstract：:We have investigated the ability of two species of streptococci isolated from the human oral cavity (Streptococcus mutans NCTC 10449 and Streptococcus sobrinus SL-1) to metabolize N-acetylglucosamine (GlcNAc), a naturally occurring amino sugar present in saliva and human glycoproteins, when provided as the sole fermen...

journal_title：Infection and immunity

authors： Homer KA,Patel R,Beighton D

更新日期：1993-01-01 00:00:00

abstract：:A dialyzable factor(s) in human serum is known to stimulate gonococcal oxygen consumption. Its effect on other human pathogens was investigated. A 10% serum solution increased peak O2 consumption for Escherichia coli and Staphylococcus aureus to 157% (P less than 0.05) and 199% (P less than 0.02), respectively, of the...

journal_title：Infection and immunity

authors： Britigan BE,Cohen MS

更新日期：1986-06-01 00:00:00

abstract：:During bacterial infection of the bovine mammary gland, large numbers of leukocytes migrate into the udder, resulting in the establishment of a host response against the pathogen. Currently, the specific leukocyte populations mediating this immune response are not well defined. In the studies described here, we analyz...

journal_title：Infection and immunity

authors： Soltys J,Quinn MT

更新日期：1999-12-01 00:00:00

abstract：:Immunization of New Zealand White rabbits with purified visna virus elicited antibody activity demonstrated by passive hemagglutination (PHA), complement fixation (CF), and indirect immunofluorescent tests. The antibody activities of hyperimmune sera and Sephadex G-200 fractions of the sera were studied. It was found ...

journal_title：Infection and immunity

authors： Karl SC,Thormar H

更新日期：1971-12-01 00:00:00

abstract：:It was found that cells of Nocardia asteroides GUH-2 (virulent) were approximately 10 times more virulent than cells of N. asteroides 14759 (intermediate) and greater that 500 times more virulent than N. asteroides 10905 (avirulent) cells when early-stationary-phase cultures suspended in saline were injected intraven...

journal_title：Infection and immunity

authors： Beaman BL,Maslan S

更新日期：1977-06-01 00:00:00

abstract：:Protective immunity against pulmonary tuberculosis (TB) is characterized by the formation in the lungs of granulomas consisting of macrophages and activated T cells producing tumor necrosis factor alpha and gamma interferon, both required for the activation of the phagocytes. In 90% of immunocompetent humans, this res...

journal_title：Infection and immunity

authors： Kaplan G,Post FA,Moreira AL,Wainwright H,Kreiswirth BN,Tanverdi M,Mathema B,Ramaswamy SV,Walther G,Steyn LM,Barry CE 3rd,Bekker LG

更新日期：2003-12-01 00:00:00

abstract：:The interaction of purified human fibrinogen with Aspergillus fumigatus conidia was investigated by immunofluorescence and electron microscopy and binding assays with radiolabeled proteins. We described the localization of the binding sites on the A. fumigatus conidia and on the fibrinogen molecule and determined the ...

journal_title：Infection and immunity

authors： Annaix V,Bouchara JP,Larcher G,Chabasse D,Tronchin G

更新日期：1992-05-01 00:00:00

abstract：:Type IV pili (Tfp) of gram-negative species share many characteristics, including a common architecture and conserved biogenesis pathway. Much less is known about the regulation of Tfp expression in response to changing environmental conditions. We investigated the diversity of Tfp regulatory systems by searching for ...

journal_title：Infection and immunity

authors： Boekema BK,Van Putten JP,Stockhofe-Zurwieden N,Smith HE

更新日期：2004-02-01 00:00:00

abstract：:To test the hypothesis that the Staphylococcus aureus enterotoxin gene cluster (egc) can generate new enterotoxin genes by recombination, we analyzed the egc locus in a broad panel of 666 clinical isolates of S. aureus. egc was present in 63% of isolates, confirming its high prevalence. The archetypal organization of ...

journal_title：Infection and immunity

authors： Thomas DY,Jarraud S,Lemercier B,Cozon G,Echasserieau K,Etienne J,Gougeon ML,Lina G,Vandenesch F

更新日期：2006-08-01 00:00:00

abstract：:Glucan-binding protein B (GbpB) from Streptococcus mutans has been shown to induce protective immunity to dental caries in experimental models. Having recently sequenced the gbpB gene, our objective in this study was to identify immunogenic regions within the GbpB sequence for use in subunit vaccines. Potential region...

journal_title：Infection and immunity

authors： Smith DJ,King WF,Barnes LA,Peacock Z,Taubman MA

更新日期：2003-03-01 00:00:00

abstract：:Antibodies directed against Pfs25, a protein present on the surface of zygotes and ookinetes of Plasmodium falciparum, completely block pathogen transmission. We evaluated the immunomodulatory effect of CpG oligodeoxynucleotides (ODN) on the immunogenicity of recombinant Pfs25 (rPfs25) formulated in alum (Al). Immuniz...

journal_title：Infection and immunity

authors： Coban C,Ishii KJ,Stowers AW,Keister DB,Klinman DM,Kumar N

更新日期：2004-01-01 00:00:00

abstract：:Recurrent urinary tract infections (UTIs) are a significant clinical problem for many women; however, host susceptibility factors have not been completely defined. The mouse model of induced UTI provides an experimental environment in which to identify specific host characteristics that are important in initial bacter...

journal_title：Infection and immunity

authors： Hopkins WJ,Gendron-Fitzpatrick A,Balish E,Uehling DT

更新日期：1998-06-01 00:00:00

abstract：:Edema disease (ED) of weanling pigs is caused by an infection with Escherichia coli that produces Shiga-like toxin II variant (SLT-IIv). Pathology identical to that caused by ED can be duplicated in pigs that are injected with less than 10 ng of purified SLT-IIv per kg of body weight. Therefore, SLT-IIv was mutated to...

journal_title：Infection and immunity

authors： Gordon VM,Whipp SC,Moon HW,O'Brien AD,Samuel JE

更新日期：1992-02-01 00:00:00

abstract：:Bile aspirated from chicken gall bladders was found to contain substances neutralizing Newcastle disease virus (NDV). Nonspecific factors were present in the bile, probably the bile acids, which caused a reduction in the infectivity of the virus. Specific anti-NDV activity was found in the bile of birds that had been ...

journal_title：Infection and immunity

authors： Lee JS,Hanson RP

更新日期：1975-04-01 00:00:00

abstract：:Bioluminescent reporter assays have been widely used to study the effect of Toxoplasma gondii on host gene expression. In the present study, we extend these studies by engineering novel reporter cell lines containing a gamma-activated sequence (GAS) element driving firefly luciferase (FLUC). In RAW264.7 macrophages, T...

journal_title：Infection and immunity

authors： Olias P,Sibley LD

更新日期：2016-06-23 00:00:00

abstract：:Urogenital Chlamydia serovars replicating in reproductive epithelium pose a unique challenge to host immunity and vaccine development. Previous studies have shown that CD4 T cells are necessary and sufficient to clear primary Chlamydia muridarum genital tract infections in the mouse model, making a protective CD4 T ce...

journal_title：Infection and immunity

authors： Johnson RM,Yu H,Kerr MS,Slaven JE,Karunakaran KP,Brunham RC

更新日期：2012-06-01 00:00:00

abstract：:Previous studies have demonstrated that the Moraxella catarrhalis surface antigen UspA1 is an adhesin for Chang human conjunctival cells. The present report demonstrates that lack of UspA1 expression does not affect the adherence of strain O35E to A549 human lung cells or primary cultures of human middle ear epithelia...

journal_title：Infection and immunity

authors： Holm MM,Vanlerberg SL,Sledjeski DD,Lafontaine ER

更新日期：2003-09-01 00:00:00