Opposite effects of human monocytes, macrophages, and polymorphonuclear neutrophils on replication of Blastomyces dermatitidis in vitro.

abstract：:Strains of Corynebacterium ulcerans and Corynebacterium pseudotuberculosis (Corynebacterium ovis) were examined for the production of diphtheria toxin. A majority of C. ulcerans strains (25 of 37) and 1 C. pseudotuberculosis strain (1 of 14) gave a positive Elek test for diphtheria toxin, and for all strains but 1, pr...

journal_title：Infection and immunity

authors： Groman N,Schiller J,Russell J

更新日期：1984-08-01 00:00:00

abstract：:Cellular resistance to facultative intracellular parasites has been studied by determining the antimycobacterial activity and the amount of fatty acids in sera and in heptane extracts of freshly collected and 24-h-cultured normal and activated guinea pig alveolar macrophages and liver cells. The quantity and the antim...

journal_title：Infection and immunity

authors： Hemsworth GR,Kochan I

更新日期：1978-01-01 00:00:00

abstract：:When tested for their activity in suppressing the acquisition of immunity during acute Besnoitia infection of hamsters, antilymphocyte serum (ALS), aminopterin, cyclophosphamide, cortisol, and whole-body irradiation were the most active agents and effectively blocked the development of immunity during 4 to 12 days of ...

journal_title：Infection and immunity

authors： Wilson HR,Frenkel JK

更新日期：1971-06-01 00:00:00

abstract：:The effects of heat and chemical inactivation on the antigenicity and immunogenicity of Vibrio cholerae 1418 in rabbits were studied. V. cholerae 1418 was inactivated with heat and chemical inactivants (phenol or Formalin) alone or in combination. Enzyme-linked immunoassay systems employing whole cells of V. cholerae ...

journal_title：Infection and immunity

authors： Cryz SJ Jr,Fürer E,Germanier R

更新日期：1982-10-01 00:00:00

abstract：:Group B streptococci (GBS) are the major cause of neonatal pneumonia, sepsis, and meningitis. Steps considered to be important in the pathogenesis of this infection include colonization of the rectum and vagina of the mother, aspiration of GBS into the fetal lung during or just prior to delivery, and invasion of GBS i...

journal_title：Infection and immunity

authors： Tamura GS,Kuypers JM,Smith S,Raff H,Rubens CE

更新日期：1994-06-01 00:00:00

abstract：:Pneumocystis carinii pneumonia (PcP) is a clinically important infection of immunocompromised patients. Although the interaction of Pneumocystis with the alveolar epithelium has been well documented, very little information regarding the epithelial response to Pneumocystis is currently available. In order to study Pne...

journal_title：Infection and immunity

authors： Wang J,Gigliotti F,Maggirwar S,Johnston C,Finkelstein JN,Wright TW

更新日期：2005-05-01 00:00:00

abstract：:Reverse transcriptase PCR analyses have demonstrated that open reading frames (ORFs) PM0298, PM0299, and PM0300 of the animal pathogen Pasteurella multocida constitute a single transcriptional unit. By cloning and overexpression studies in Escherichia coli cells, the product of ORF PM0300 was shown to bind hemoglobin ...

journal_title：Infection and immunity

authors： Bosch M,Garrido ME,Llagostera M,Pérez De Rozas AM,Badiola I,Barbé J

更新日期：2002-11-01 00:00:00

abstract：:The proinflammatory cytokine tumor necrosis factor alpha (TNF-alpha) induces lethal hepatitis when injected into D-(+)-galactosamine-sensitized mice on the one hand or systemic inflammatory response syndrome (SIRS) in normal mice on the other hand. We studied whether serum amyloid P component (SAP), the major acute-ph...

journal_title：Infection and immunity

authors： Van Molle W,Hochepied T,Brouckaert P,Libert C

更新日期：2000-09-01 00:00:00

abstract：:The mechanisms of genetic resistance or "trypanotolerance" to infection with Trypanosoma congolense were investigated in two strains of mice. One strain C57BL, is outstandingly resistant to most stabilates of T. congolense and can survive for over 80 days, whereas CFLP, in common with most other strains, generally suc...

journal_title：Infection and immunity

authors： Whitelaw DD,Macaskill JA,Holmes PH,Jennings FW,Urquhart GM

更新日期：1980-03-01 00:00:00

abstract：:The cell surface of Chlamydia psittaci seems important for establishing infection since (i) UV-treated elementary bodies (EB) attach to and are ingested by L cells and (ii) heat or antibody treatment decreases attachment to L cells and promotes the fusion of chlamydiae-containing phagosomes with lysosomes in macrophag...

journal_title：Infection and immunity

authors： Eissenberg LG,Wyrick PB,Davis CH,Rumpp JW

更新日期：1983-05-01 00:00:00

abstract：:Numerous studies have reported that asialo-GM(1), gangliotetraosylceramide, or moieties serve as epithelial cell receptors for Pseudomonas aeruginosa. Usually this interaction is confirmed with antibodies to asialo-GM(1). However, few, if any, of these reports have evaluated the binding of fresh clinical isolates of P...

journal_title：Infection and immunity

authors： Schroeder TH,Zaidi T,Pier GB

更新日期：2001-02-01 00:00:00

abstract：:Lewis (Le) antigens have been implicated in the pathogenesis of atrophic gastritis and gastric cancer in the setting of Helicobacter pylori infection, and H. pylori-induced anti-Le antibodies have been described that cross-react with the gastric mucosa of both mice and humans. The aim of this study was to examine the ...

journal_title：Infection and immunity

authors： Heneghan MA,McCarthy CF,Janulaityte D,Moran AP

更新日期：2001-08-01 00:00:00

abstract：:Streptococcus pneumoniae, a Gram-positive bacterial pathogen, causes pneumonia, meningitis, and septicemia. Innate immune responses are critical for the control and pathology of pneumococcal infections. It has been demonstrated that S. pneumoniae induces the production of type I interferons (IFNs) by host cells and th...

journal_title：Infection and immunity

authors： Fang R,Hara H,Sakai S,Hernandez-Cuellar E,Mitsuyama M,Kawamura I,Tsuchiya K

更新日期：2014-06-01 00:00:00

abstract：:Four strains of Staphylococcus aureus of a phage type other than the second group, isolated from patients with impetigo and Ritter's disease, were found to produce an exotoxin similar to those reported by Melish et al. (1972), Kapral and Miller (1971), and Arbuthnott et al. (1973). This toxin could elicit a general ex...

journal_title：Infection and immunity

authors： Kondo I,Sakurai S,Sarai Y

更新日期：1974-10-01 00:00:00

abstract：:Attenuated Yersinia pestis pgm strains, such as KIM5, lack the siderophore yersiniabactin. Strain KIM5 does not induce significant pneumonia when delivered intranasally. In this study, mice were found to develop pneumonia after intranasal challenge with strain KIM5 when they were injected intraperitoneally with iron d...

journal_title：Infection and immunity

authors： Galván EM,Nair MK,Chen H,Del Piero F,Schifferli DM

更新日期：2010-08-01 00:00:00

abstract：:Phenethyl alcohol, at the maximum concentration which did not inhibit growth (0.3% [vol/vol]), inhibited the production of alpha-lysin and exoproteases but not that of delta-lysin in Staphylococcus aureus Wood 46. The inhibition of alpha-lysin was reversible, and transient accumulation of cell-associated alpha-lysin o...

journal_title：Infection and immunity

authors： Lee KY,Birkbeck TH

更新日期：1985-01-01 00:00:00

abstract：:Isolated Bacteroides gingivalis 2561 vesicles aggregated suspensions of Actinomyces viscosus and Actinomyces naeslundii of all taxonomy clusters. Vesicles bound near A. viscosus cell walls and among its surface fibrils. Tritiated vesicles bound slightly better to saliva-coated hydroxyapatite (SHA) than to SHA coated w...

journal_title：Infection and immunity

authors： Ellen RP,Grove DA

更新日期：1989-05-01 00:00:00

abstract：:The glycolipid haptens of Mycoplasma pneumoniae became immunogenic when bound to membrane proteins of Acholeplasma laidlawii by reaggregation. This process consisted of the solubilization of lipid-depleted A. laidlawii membranes and M. pneumoniae glycolipids in 20 mm sodium dodecyl sulfate and dialysis of the mixed so...

journal_title：Infection and immunity

authors： Razin S,Prescott B,James WD,Caldes G,Valdesuso J,Chanock RM

更新日期：1971-03-01 00:00:00

abstract：:Spleen cell cultures from guinea pigs given legionella pneumophila vaccine in complete Freund adjuvant or as a sublethal infection were inhibited in their migration activity in vitro when incubated with specific antigen. Both direct and indirect migration inhibition assays revealed sensitization of the guinea pigs to ...

journal_title：Infection and immunity

authors： Friedman H,Widen R,Lee I,Klein T

更新日期：1983-09-01 00:00:00

abstract：:The ocular surface is continuously exposed to potential pathogens, including free-living amoebae. Acanthamoeba species are among the most ubiquitous amoebae, yet Acanthamoeba keratitis is remarkably rare. The pathogenesis of Acanthamoeba keratitis is a complex, sequential process. Here we show that Acanthamoeba kerati...

journal_title：Infection and immunity

authors： Alizadeh H,Neelam S,Hurt M,Niederkorn JY

更新日期：2005-02-01 00:00:00

abstract：:Urease activity has recently been shown to be an important virulence determinant for Helicobacter pylori, allowing it to survive the low pH of the stomach during colonization. Experimental murine infection with Helicobacter felis is now being used as a model for H. pylori infection to study the effects of vaccines, an...

journal_title：Infection and immunity

authors： Gootz TD,Perez-Perez GI,Clancy J,Martin BA,Tait-Kamradt A,Blaser MJ

更新日期：1994-03-01 00:00:00

abstract：:Borrelia burgdorferi, the causative agent of Lyme arthritis, does not produce any exported proteases capable of degrading extracellular matrix despite the fact that it is able to disseminate from a skin insertion site to infect multiple organs. Prior studies have shown that B. burgdorferi induces the host protease, ma...

journal_title：Infection and immunity

authors： Heilpern AJ,Wertheim W,He J,Perides G,Bronson RT,Hu LT

更新日期：2009-07-01 00:00:00

abstract：:The effect of a standard regimen of cimetidine on the gastric flora of 20 male volunteers was studied in a double-blind manner and compared with the effects of a standard antacid regimen. Postprandial microbial titers in gastric aspirates were significantly higher at 4, 8, and 16 weeks of therapy in subjects taking an...

journal_title：Infection and immunity

authors： Snepar R,Poporad GA,Romano JM,Kobasa WD,Kaye D

更新日期：1982-05-01 00:00:00

abstract：:Bordetella pertussis, a causative agent of whooping cough, expresses BrkA, which confers serum resistance, but the closely related human pathogen that also causes whooping cough, Bordetella parapertussis, does not. Interestingly, B. parapertussis, but not B. pertussis, produces an O antigen, a factor shown in other mo...

journal_title：Infection and immunity

authors： Goebel EM,Wolfe DN,Elder K,Stibitz S,Harvill ET

更新日期：2008-04-01 00:00:00

abstract：:This work evaluated the kinetics of events that occur in the placenta of Calomys callosus after Toxoplasma gondii infection. Animals on the first day of pregnancy (dop) and virgin nonpregnant females were perorally infected with 20 cysts of T. gondii strain ME49. After 100 days of infection, the virgin animals were ma...

journal_title：Infection and immunity

authors： Ferro EA,Silva DA,Bevilacqua E,Mineo JR

更新日期：2002-12-01 00:00:00

abstract：:Cord factor (trehalose 6,6'-dimycolate[TDM] ), a mixture of 6,6'-diesters of alpha, alpha-D-trehalose with natural mycolic acids, has been described as having immunoregulatory and antitumor activities in vivo, although the relevant mechanisms of action remain unelucidated. In this work, we measured the effects of TDM ...

journal_title：Infection and immunity

authors： Kierszenbaum F,Zenian A,Wirth JJ

更新日期：1984-02-01 00:00:00

abstract：:Subchronic exposure to pharmacological levels of estrogenic compounds, including 17 beta-estradiol, diethylstilbestrol, and alpha-dienestrol, significantly increased the mortality of B6C3F1 female mice after Listeria infection. Compounds with little estrogenic activity, including 5 alpha-dihydrotestosterone, progester...

journal_title：Infection and immunity

authors： Pung OJ,Luster MI,Hayes HT,Rader J

更新日期：1984-11-01 00:00:00

abstract：:Alveolar macrophages are the effector cells largely responsible for clearance of Pneumocystis carinii from the lungs. Binding of organisms to beta-glucan and mannose receptors has been shown to stimulate phagocytosis of the organisms. To further define the mechanisms used by alveolar macrophages for clearance of P. ca...

journal_title：Infection and immunity

authors： Hollifield M,Bou Ghanem E,de Villiers WJ,Garvy BA

更新日期：2007-08-01 00:00:00

abstract：:The bactericidal activity of guinea pig and human polymorphonuclear leukocytes (PMNs) against a smooth-intermediate strain (45/0) and a rough strain (45/20) of Brucella abortus has been examined. After incubation for 120 min, guinea pig PMNs incubated with either the smooth strain 45/0 or the rough strain 45/20 exhibi...

journal_title：Infection and immunity

authors： Kreutzer DL,Dreyfus LA,Robertson DC

更新日期：1979-03-01 00:00:00

abstract：:The primary effector for Shigella invasion of epithelial cells is IpaC, which is secreted via a type III secretion system. We recently reported that the IpaC N terminus is required for type III secretion and possibly other functions. In this study, mutagenesis was used to identify an N-terminal secretion signal and to...

journal_title：Infection and immunity

authors： Harrington AT,Hearn PD,Picking WL,Barker JR,Wessel A,Picking WD

更新日期：2003-03-01 00:00:00