Replication of dengue and junin viruses in cultured rabbit and human endothelial cells.

abstract：:Previous studies found that normal human serum (NHS) contains an immunoglobulin G (IgG) antibody that mediates initiation of the classical complement pathway by nonencapsulated Cryptococcus neoformans. The present study used an enzyme-linked immunosorbent assay with whole nonencapsulated yeast cells as solid-phase ant...

journal_title：Infection and immunity

authors： Keller RG,Pfrommer GS,Kozel TR

更新日期：1994-01-01 00:00:00

abstract：:Monoclonal antibodies (TpM 3, TpM 6, and TpM 19) against Toxoplasma gondii insoluble antigens were produced by the hybridization of NS-1, a mouse myeloma cell line, with spleen cells from mice immunized with T. gondii insoluble antigens. TpM 3, TpM 6, and TpM 19 were characterized by the dye test, the latex agglutinat...

journal_title：Infection and immunity

authors： Ogata K,Kasahara T,Shioiri-Nakano K,Igarashi I,Suzuki M

更新日期：1984-03-01 00:00:00

abstract：:Clostridium perfringens delta toxin was selectively cytotoxic for various rabbit leukocyte populations. The sensitivity of these populations to the toxin varied, depending on the tissue from which they were derived, from 28% (appendix) to 41% (bone marrow) and 32% (spleen). Macrophages were uniformly killed by delta t...

journal_title：Infection and immunity

authors： Jolivet-Reynaud C,Cavaillon JM,Alouf JE

更新日期：1982-12-01 00:00:00

abstract：:F344 rats chronically infected with Ureaplasma parvum develop two distinct profiles: asymptomatic urinary tract infection (UTI) and UTI complicated by struvite urolithiasis. To identify factors that affect disease outcome, we characterized the temporal host immune response during infection by histopathologic analysis ...

journal_title：Infection and immunity

authors： Reyes L,Alvarez S,Allam A,Reinhard M,Brown MB

更新日期：2009-10-01 00:00:00

abstract：:Actinomyces viscosus ATCC 15987 was examined for the presence of cell-associated levan by absorption of myeloma proteins with antilevan activity and direct immunofluorescence. Levan was not detectable on the surface of glucose-grown A. viscosus, but after a brief incubation of these cells with 5% sucrose, they were en...

journal_title：Infection and immunity

authors： Warner TN,Miller CH

更新日期：1978-02-01 00:00:00

abstract：:Acute pyelonephritis, a complication of Escherichia coli bacteriuria, must represent a bacterial invasion through the kidney epithelium. To study this process, we overlaid bacterial suspensions onto monolayers of cultured human kidney proximal tubular epithelial cells and measured cytotoxicity by release of lactate de...

journal_title：Infection and immunity

authors： Mobley HL,Green DM,Trifillis AL,Johnson DE,Chippendale GR,Lockatell CV,Jones BD,Warren JW

更新日期：1990-05-01 00:00:00

abstract：:Cross-reactive humoral immune responses between antigens of different developmental stages of the worm Schistosoma mansoni have previously been demonstrated. In contrast, information on antigenic cross-reactivity at the T-cell level is still very sparse. The present study examined the cross-reactive T-cell responses t...

journal_title：Infection and immunity

authors： Lukacs NW,Boros DL

更新日期：1991-09-01 00:00:00

abstract：:Infection with Cryptosporidium parvum, a ubiquitous protozoan parasite of virtually all mammals, can cause mild to severe diarrhea in immunocompetent hosts and life-threatening diarrhea in immunocompromised hosts. Passive immunotherapy of experimentally infected animals and naturally infected humans with hyperimmune b...

journal_title：Infection and immunity

authors： Fayer R,Guidry A,Blagburn BL

更新日期：1990-09-01 00:00:00

abstract：:Virus population dynamics in the lungs, trachea, and nasopharynx of Swiss-ICR mice were studied after respiratory challenge with mouse-adapted preparations of strain A2/Aichi/2/68 influenza virus. Markedly higher doses of virus were required to produce infection with nasopharyngeal challenge than with bronchoalveolar ...

journal_title：Infection and immunity

authors： Larson EW,Dominik JW,Rowberg AH,Higbee GA

更新日期：1976-02-01 00:00:00

abstract：:Cattle are an important reservoir of Shiga toxin-producing enterohemorrhagic Escherichia coli (EHEC) O157:H7 strains, foodborne pathogens that cause hemorrhagic colitis and hemolytic uremic syndrome in humans. EHEC O157:H7 strains are not pathogenic in calves >3 weeks old. Our objective was to determine if EHEC O157:H...

journal_title：Infection and immunity

authors： Dean-Nystrom EA,Bosworth BT,Cray WC Jr,Moon HW

更新日期：1997-05-01 00:00:00

abstract：:Bovine digital dermatitis (BDD), an infectious disease of the bovine foot with a predominant treponemal etiology, is a leading cause of lameness in dairy and beef herds worldwide. BDD is poorly responsive to antimicrobial therapy and exhibits a relapsing clinical course; an effective vaccine is therefore urgently soug...

journal_title：Infection and immunity

authors： Staton GJ,Carter SD,Ainsworth S,Mullin J,Smith RF,Evans NJ

更新日期：2020-04-20 00:00:00

abstract：:Mice were inoculated with Legionella pneumophila via an intratracheal route to establish an experimental model of infection. Lung lavage fluid obtained from infected mice contained a cytolytic factor identified as tumor necrosis factor (TNF). Peak levels of TNF were produced at about 24 h postinfection and rapidly dec...

journal_title：Infection and immunity

authors： Blanchard DK,Djeu JY,Klein TW,Friedman H,Stewart WE 2nd

更新日期：1987-02-01 00:00:00

abstract：:Local gingival immunization was attempted in an effort to confine the immune response to the oral cavity and bypass the systemic immune response. A low-molecular-weight (3.8K) streptococcal antigen (SA) I/II was applied 10 times over a period of 1 year to the gingival crevices of rhesus monkeys. The antigen was mainta...

journal_title：Infection and immunity

authors： Lehner T,Mehlert A,Caldwell J

更新日期：1986-06-01 00:00:00

abstract：:A purified A-antigen preparation of Blastomyces dermatitidis was determined to be composed of five major glycoprotein bands, visible with Coomassie blue and periodic acid-Schiff staining of polyacrylamide gels. At least 20 additional protein bands were detected by using a silver stain, which was 100 times more sensiti...

journal_title：Infection and immunity

authors： Young KD,Larsh HW

更新日期：1981-07-01 00:00:00

abstract：:The serotype-specific polysaccharide of Streptococcus mutans AHT (serotype a) was shown to be loosely associated with the cell surface of this organism. The antigen was extracted from whole cells by boiling in sodium acetate buffer, pH 4.0, for 10 min. The purified product was found to be a diheteroglycan of galactose...

journal_title：Infection and immunity

authors： Craig RA,Riege DH,Bleiweis AS

更新日期：1979-12-01 00:00:00

abstract：:Our previous studies demonstrated that Mycobacterium bovis bacillus Calmette-Guérin (BCG) can directly interact with human NK cells and induce the proliferation, gamma interferon production, and cytotoxic activity of such cells without the need for accessory cells. Thus, the aim of the present study was to identify th...

journal_title：Infection and immunity

authors： Esin S,Batoni G,Counoupas C,Stringaro A,Brancatisano FL,Colone M,Maisetta G,Florio W,Arancia G,Campa M

更新日期：2008-04-01 00:00:00

abstract：:Anaplasma phagocytophilum is an obligate intracellular bacterium that infects myeloid cells in the mammalian host. Msp2 (p44) is the major immunodominant outer-membrane protein of these bacteria. We hypothesized that Msp2 acts as an adhesin for A. phagocytophilum entry into granulocytes. This potential role was invest...

journal_title：Infection and immunity

authors： Park J,Choi KS,Dumler JS

更新日期：2003-07-01 00:00:00

abstract：:We have cloned chromosomal genes mediating the aerobactin iron transport system from the enteroinvasive strain Escherichia coli 978-77. The physical map of the region spanning the siderophore biosynthesis genes and the upstream portion of the receptor gene in strain 978-77-derived clones was identical to the correspon...

journal_title：Infection and immunity

authors： Marolda CL,Valvano MA,Crosa JH

更新日期：1991-01-01 00:00:00

abstract：:Murine hybridoma cell lines were developed which synthesized monoclonal antibodies against Actinobacillus actinomycetemcomitans-associated antigens. Monoclonal antibodies specific for an antigen(s) common to all A. actinomycetemcomitans isolates tested but not detected on other gram-negative oral plaque microorganisms...

journal_title：Infection and immunity

authors： Place DA,Scidmore NC,McArthur WP

更新日期：1988-05-01 00:00:00

abstract：:A cytoplasmic 75-kDa immunogen from Chlamydia trachomatis serovar L2 has previously been characterized as being similar to the Escherichia coli heat shock protein DnaK. We have localized a linear epitope for one monoclonal antibody specific for C. trachomatis DnaK. By use of a recombinant DNA technique, the epitope wa...

journal_title：Infection and immunity

authors： Birkelund S,Larsen B,Holm A,Lundemose AG,Christiansen G

更新日期：1994-05-01 00:00:00

abstract：:The mechanism of complement-mediated killing of seven serum-sensitive Pseudomonas aeruginosa strains was examined. All seven strains were sensitive to the bactericidal activity of 20% pooled normal human serum (PNHS) containing magnesium EGTA, which blocks the classical complement pathway (CCP), or 20% PNHS preheated ...

journal_title：Infection and immunity

authors： Schiller NL

更新日期：1988-03-01 00:00:00

abstract：:Performing patch-clamp experiments on human macrophages, we show that the K(+) channel MaxiK is activated by lipopolysaccharide, peptidoglycan, and interleukin-1. Cytokine production initiated by several Toll-like receptor (TLR) ligands and by interleukin-1 is inhibited by MaxiK blockade. This provides evidence for fu...

journal_title：Infection and immunity

authors： Scheel O,Papavlassopoulos M,Blunck R,Gebert A,Hartung T,Zähringer U,Seydel U,Schromm AB

更新日期：2006-07-01 00:00:00

abstract：:Biofilm formation by the periodontal pathogen Aggregatibacter actinomycetemcomitans is dependent upon autoinducer-2 (AI-2)-mediated quorum sensing. However, the components that link the detection of the AI-2 signal to downstream gene expression have not been determined. One potential regulator is the QseBC two-compone...

journal_title：Infection and immunity

authors： Novak EA,Shao H,Daep CA,Demuth DR

更新日期：2010-07-01 00:00:00

abstract：:Conventional adult mice were pretreated with metronidazole to make their intestinal tracts receptive to colonization by Clostridium botulinum. These mice, in groups of 10, were fed 0 (controls), 10(2), 10(3), 10(4), or 10(5) C. botulinum type B spores and were placed for observation in filter-lid cages whose screen fl...

journal_title：Infection and immunity

authors： Wang Y,Sugiyama H

更新日期：1984-12-01 00:00:00

abstract：:No studies to date clearly define the interactions between Porphyromonas gingivalis and human peripheral blood polymorphonuclear leukocytes (PMN), nor has a protective role for antibody to P. gingivalis been defined. Using a fluorochrome phagocytosis microassay, we investigated PMN phagocytosis and killing of P. gingi...

journal_title：Infection and immunity

authors： Cutler CW,Kalmar JR,Arnold RR

更新日期：1991-06-01 00:00:00

abstract：:Colonization of the large bowel of healthy infants by Clostridium difficile was studied. Feces were collected from five breast-fed aand five formula-fed infants throughout the first year of life, and levels of C. difficile were quantitated. Three breast-fed and five formula-fed infants were colonized for periods of be...

journal_title：Infection and immunity

authors： Stark PL,Lee A,Parsonage BD

更新日期：1982-03-01 00:00:00

abstract：:The unique permissiveness of A/J mouse macrophages for replication of Legionella pneumophila is caused by a deficiency in the Nod-like receptor (NLR) protein and intracellular sensor for L. pneumophila flagellin (Naip5). The signaling pathways and proteins activated by Naip5 sensing in macrophages were investigated. T...

journal_title：Infection and immunity

authors： Fortier A,Doiron K,Saleh M,Grinstein S,Gros P

更新日期：2009-11-01 00:00:00

abstract：:In experimentally infected human volunteers, the cutaneous immune response to Haemophilus ducreyi is orchestrated by serum, polymorphonuclear leukocytes, macrophages, T cells, and myeloid dendritic cells (DC). This response either leads to spontaneous resolution of infection or progresses to pustule formation, which i...

journal_title：Infection and immunity

authors： Humphreys TL,Li L,Li X,Janowicz DM,Fortney KR,Zhao Q,Li W,McClintick J,Katz BP,Wilkes DS,Edenberg HJ,Spinola SM

更新日期：2007-12-01 00:00:00

abstract：:Immune cytolysis was measured by release of absorbed radioactive chromium from infected cells that were incubated with antiviral antibody and complement. The presence of virus-specific antigens detected in this manner on the surface of several types of cells infected with Japanese encephalitis (JE) virus did not corre...

journal_title：Infection and immunity

authors： Brandt WE,Russell PK

更新日期：1975-02-01 00:00:00

abstract：:The ability of intracellular pathogens to sense and adapt to the hostile environment of the host is an important factor governing virulence. We have sequenced the operon encoding the major heat shock proteins GroES and GroEL in the gram-positive food-borne pathogen Listeria monocytogenes. The operon has a conserved or...

journal_title：Infection and immunity

authors： Gahan CG,O'Mahony J,Hill C

更新日期：2001-06-01 00:00:00