Antigens of Streptococcus mutans: cellular localization of the serotype-specific polysaccharide of strain AHT and release during exponential growth.

abstract：:Transforming growth factor beta (TGF-beta) has been shown to be a central immunomodulator used by leishmaniae to escape effective mechanisms of protection in human and murine infections with these parasites. However, all the information is derived from studies of established infection, while little is known about TGF-...

journal_title：Infection and immunity

authors： Kariminia A,Bourreau E,Pascalis H,Couppié P,Sainte-Marie D,Tacchini-Cottier F,Launois P

更新日期：2005-09-01 00:00:00

abstract：:Periodontitis is a bacterium-induced chronic inflammation that destroys tissues that attach teeth to jaw bone. Pathologically excessive matrix metalloproteinase 8 (MMP-8) is among the key players in periodontal destruction by initiating type I collagen degradation. We studied MMP-8 in Porphyromonas gingivalis-induced ...

journal_title：Infection and immunity

authors： Kuula H,Salo T,Pirilä E,Tuomainen AM,Jauhiainen M,Uitto VJ,Tjäderhane L,Pussinen PJ,Sorsa T

更新日期：2009-02-01 00:00:00

abstract：:Brazilian purpuric fever (BPF)-associated Haemophilus influenzae biogroup aegyptius strain F3031 contains two identical copies of a five gene cluster (hifA to hifE) encoding pili similar to well-characterized Hif fimbriae of H. influenzae type b. HifE, the putative pilus tip adhesin of F3031, shares only 40% amino aci...

journal_title：Infection and immunity

authors： Read TD,Satola SW,Opdyke JA,Farley MM

更新日期：1998-04-01 00:00:00

abstract：:Streptococcus mutans is one of the best-known biofilm-forming organisms associated with humans. We investigated the role of the sortase gene (srtA) in monospecies biofilm formation and observed that inactivation of srtA caused a decrease in biofilm formation. Genes encoding three putative sortase-dependent proteins we...

journal_title：Infection and immunity

authors： Lévesque CM,Voronejskaia E,Huang YC,Mair RW,Ellen RP,Cvitkovitch DG

更新日期：2005-06-01 00:00:00

abstract：:Streptococcus iniae causes meningoencephalitis and death in commercial fish species and has recently been identified as an emerging human pathogen producing fulminant soft tissue infection. As identified by pulsed-field gel electrophoresis (PFGE), strains causing disease in either fish or humans belong to a single clo...

journal_title：Infection and immunity

authors： Fuller JD,Bast DJ,Nizet V,Low DE,de Azavedo JC

更新日期：2001-04-01 00:00:00

abstract：:Fonsecaea pedrosoi is a fungal pathogen that produces melanin. The functions of melanin and its possible influence in the protective immunological response during infection by F. pedrosoi are not known. In this work, treatment of F. pedrosoi mycelia with proteases and glycosidases followed by a denaturing agent and ho...

journal_title：Infection and immunity

authors： Alviano DS,Franzen AJ,Travassos LR,Holandino C,Rozental S,Ejzemberg R,Alviano CS,Rodrigues ML

更新日期：2004-01-01 00:00:00

abstract：:It was previously determined that the type II secretion system (T2SS) promotes the ability of Legionella pneumophila to grow in coculture with amoebae. Here, we discerned the stage of intracellular infection that is potentiated by comparing the wild-type and T2SS mutant legionellae for their capacity to parasitize Aca...

journal_title：Infection and immunity

authors： White RC,Truchan HK,Zheng H,Tyson JY,Cianciotto NP

更新日期：2019-10-18 00:00:00

abstract：:Pathogenic Leptospira spp. are likely to encounter higher concentrations of reactive oxygen species induced by the host innate immune response. In this study, we characterized Leptospira interrogans catalase (KatE), the only annotated catalase found within pathogenic Leptospira species, by assessing its role in resist...

journal_title：Infection and immunity

authors： Eshghi A,Lourdault K,Murray GL,Bartpho T,Sermswan RW,Picardeau M,Adler B,Snarr B,Zuerner RL,Cameron CE

更新日期：2012-11-01 00:00:00

abstract：:When inoculated orally, Escherichia coli strain 1056 caused acute enteritis in 7 of 22 weanling hamsters. E. coli strain 1056 was isolated from the ileum of a hamster with proliferative ileitis. It was lactose negative, nonmotile, and anaerogenic. By electron microscopy and indirect fluorescent-antibody techniques, E....

journal_title：Infection and immunity

authors： Frisk CS,Wagner JE,Owens DR

更新日期：1981-03-01 00:00:00

abstract：:Vaccination with recombinant outer surface protein A (OspA) has been shown to protect mice from infection with Borrelia burgdorferi, the Lyme disease agent. To determine whether antibodies to B. burgdorferi proteins other than OspA are involved in protective immunity, antibodies to OspA were removed from protective an...

journal_title：Infection and immunity

authors： Fikrig E,Barthold SW,Marcantonio N,Deponte K,Kantor FS,Flavell RA

更新日期：1992-02-01 00:00:00

abstract：:Treatment of mouse embryo fibroblasts (MEF) grown in vitro with purified staphylococcal exfoliative toxin (ET) increased the concanavalin A (Con A) agglutinability of MEF 3.5-fold over control cells. Possible explanations for this phenomenon were investigated. ET lacked proteolytic activity on denatured casein. Con A,...

journal_title：Infection and immunity

authors： Rogolsky M,Wiley BB,Keyhani M,Glasgow LA

更新日期：1974-12-01 00:00:00

abstract：:Helicobacter pylori strains frequently express Lewis X (Le(x)) and/or Le(y) on their cell surfaces as constituents of the O antigens of their lipopolysaccharide molecules. To assess the effect of Le(x) and Le(y) expression on the ability of H. pylori to colonize the mouse stomach and to adhere to epithelial cells, iso...

journal_title：Infection and immunity

authors： Takata T,El-Omar E,Camorlinga M,Thompson SA,Minohara Y,Ernst PB,Blaser MJ

更新日期：2002-06-01 00:00:00

abstract：:Vibrio vulnificus causes rapidly progressing septicemia with an extremely high mortality rate (≥50%), even with aggressive antibiotic treatment. The bacteria secrete multifunctional autoprocessing repeats-in-toxin (MARTX) toxins, which are involved in the pathogenesis of Gram-negative Vibrio species. Recently, we repo...

journal_title：Infection and immunity

authors： Lee TH,Cha SS,Lee CS,Rhee JH,Chung KM

更新日期：2014-11-01 00:00:00

abstract：:Peptide 9 (TDAYNQKLSERRAN) and peptide 10 (NATAEGRAINRRVE) represent surface-exposed epitopes of outer membrane protein F of Pseudomonas aeruginosa. Rats immunized with four intramuscular inoculations on days 0, 14, 28, and 42 with either peptide 9 or peptide 10 conjugated to keyhole limpet hemocyanin were afforded pr...

journal_title：Infection and immunity

authors： Gilleland LB,Gilleland HE Jr

更新日期：1995-06-01 00:00:00

abstract：:Lipopolysaccharide (LPS) is an amphipathic macromolecule that is highly aggregated in aqueous preparations. LPS-binding protein (LBP) catalyzes the transfer of single LPS molecules, segregated from an LPS aggregate, to high-density lipoproteins (HDL), which results in the neutralization of LPS. When fluorescein isothi...

journal_title：Infection and immunity

authors： de Haas CJ,Poppelier MJ,van Kessel KP,van Strijp JA

更新日期：2000-09-01 00:00:00

abstract：:Spiroplasmas were propagated in the Drosophila melanogaster cell line Dm-1. Spiroplasma citri and unidentified strains (corn shunt organism, 277F [tick isolate], powder puff, BNR-1, honey bee, and OBMG) grew to 10(8) to 10(9) colony-forming units per ml and could be passaged. Cytopathic effect (CPE) varied with the in...

journal_title：Infection and immunity

authors： Steiner T,McGarrity GJ,Phillips DM

更新日期：1982-01-01 00:00:00

abstract：:The pathogenic role of staphylococcal coagulase and clumping factor was investigated in the rat model of endocarditis. The coagulase-producing and clumping factor-producing parent strain Staphylococcus aureus Newman and a series of mutants defective in either coagulase, clumping factor, or both were tested for their a...

journal_title：Infection and immunity

authors： Moreillon P,Entenza JM,Francioli P,McDevitt D,Foster TJ,François P,Vaudaux P

更新日期：1995-12-01 00:00:00

abstract：:Streptolysin-O (SLO) is a thiol-activated, membrane-damaging protein toxin of Mr 69,000 that is produced by most strains of beta-hemolytic group A streptococci. Native, primarily water-soluble toxin molecules bind to cholesterol-containing target membranes to assemble into supramolecular curved rod structures (25 to 1...

journal_title：Infection and immunity

authors： Bhakdi S,Tranum-Jensen J,Sziegoleit A

更新日期：1985-01-01 00:00:00

abstract：:Respiratory epithelial cells play an active part in the host response to respiratory pathogens, such as Streptococcus pneumoniae, by releasing chemokines responsible for neutrophil recruitment. In order to investigate the role of specific pneumococcal virulence factors in eliciting CXC chemokine responses, type II pne...

journal_title：Infection and immunity

authors： Graham RM,Paton JC

更新日期：2006-12-01 00:00:00

abstract：:A key function of monocytes/macrophages (Mphi) is to present antigens to T cells. However, upon interaction with bacteria, Mphi lose their ability to effectively present soluble antigens. This functional loss was associated with alterations in the expression of adhesion molecules and CD14 and a reduction in the uptake...

journal_title：Infection and immunity

authors： Wyant TL,Tanner MK,Sztein MB

更新日期：1999-03-01 00:00:00

abstract：:As an intracellular protozoan parasite, Toxoplasma gondii is likely to exploit proteases for host cell invasion, acquisition of nutrients, avoidance of host protective responses, escape from the parasitophorous vacuole, differentiation, and other activities. T. gondii serine protease inhibitor 1 (TgPI1) is the most ab...

journal_title：Infection and immunity

authors： Pszenny V,Davis PH,Zhou XW,Hunter CA,Carruthers VB,Roos DS

更新日期：2012-03-01 00:00:00

abstract：:Patients with chronic bronchitis are colonized by and may develop acute bronchopulmonary infection due to nontypable Haemophilus influenzae (NTHI) despite the presence of bactericidal and opsonizing antibody to the infecting organism. To test the hypothesis that secretory immunoglobulin A (IgA) interferes with host de...

journal_title：Infection and immunity

authors： Musher DM,Goree A,Baughn RE,Birdsall HH

更新日期：1984-07-01 00:00:00

abstract：:Shiga toxin-producing Escherchia coli (STEC) comprises a group of attaching and effacing (A/E) enteric pathogens of animals and humans. Natural and experimental infection of calves with STEC may result in acute enteritis or subclinical infection, depending on serotype- and host-specific factors. To quantify intestinal...

journal_title：Infection and immunity

authors： Stevens MP,Marchès O,Campbell J,Huter V,Frankel G,Phillips AD,Oswald E,Wallis TS

更新日期：2002-02-01 00:00:00

abstract：:Microsporidia are obligate intracellular parasites that are ubiquitous in nature and have been recognized as causing an important emerging disease among immunocompromised individuals. Limited knowledge exists about the immune response against these organisms, and virtually nothing is known about the receptors involved...

journal_title：Infection and immunity

authors： Fischer J,Suire C,Hale-Donze H

更新日期：2008-10-01 00:00:00

abstract：:Formation of compact colonies of Staphylococcus aureus in serum-soft agar is mainly a result of a reaction between protein A and the Fc-part of immunoglobulin G and not a clumping factor-fibrinogen reaction. ...

journal_title：Infection and immunity

authors： Forsum U,Forsgren A,Hjelm E

更新日期：1972-10-01 00:00:00

abstract：:Encapsulated cells of Cryptococcus neoformans are potent activators of the alternative complement pathway. Previous studies found that monoclonal antibodies (MAbs) specific for the major capsular polysaccharide, termed glucuronoxylomannan (GXM), can markedly suppress the ability of the capsule to accumulate C3 from no...

journal_title：Infection and immunity

authors： Kozel TR,MacGill RS,Wall KK

更新日期：1998-04-01 00:00:00

abstract：:Candida albicans is a ubiquitous mucosal commensal that is normally prevented from causing acute or chronic invasive disease. Neutrophils contribute to protection in oral infection but exacerbate vulvovaginal candidiasis. To dissect the role of neutrophils during mucosal candidiasis, we took advantage of a new, transp...

journal_title：Infection and immunity

authors： Gratacap RL,Scherer AK,Seman BG,Wheeler RT

更新日期：2017-08-18 00:00:00

abstract：:The development and course of normally lethal parasitemias in mice inoculated intraperitoneally with erythrocytic stages of Plasmodium yoelii or Plasmodium berghei were markedly affected by treatment with the antilymphoid drug cyclosporin A (CS-A). When the first of four daily subcutaneous 25-mg/kg doses of CS-A was g...

journal_title：Infection and immunity

authors： Nickell SP,Scheibel LW,Cole GA

更新日期：1982-09-01 00:00:00

abstract：:Lipopolysaccharides obtained from Brucella abortus, B. melitensis, and B. suis, but not B. canis, were found to contain amino sugars identified as glucosamine and quinovosamine by cation exchange and thin-layer cellulose chromatography and ninhydrin degradation. ...

journal_title：Infection and immunity

authors： Bowser DV,Wheat RW,Foster JW,Leong D

更新日期：1974-04-01 00:00:00

abstract：:The rfb region from Vibrio cholerae O139 strain MO45 was cloned from cosmid gene banks established in Escherichia coli HB101, using an immunoblot assay for screening of the correct clones. Immunoblot analysis of lipopolysaccharide (LPS) preparations revealed the presence of two types of positive clones: (i) those expr...

journal_title：Infection and immunity

authors： Favre D,Cryz SJ Jr,Viret JF

更新日期：1996-09-01 00:00:00