Control of Mucosal Candidiasis in the Zebrafish Swim Bladder Depends on Neutrophils That Block Filament Invasion and Drive Extracellular-Trap Production.

abstract：:Escherichia coli O157:H7, a major Shiga toxin-producing pathogen, has a low infectious dose and causes serious illness in humans. The gastrointestinal tract of cattle is the primary reservoir of E. coli O157:H7, and thus, it is critical to eliminate or reduce E. coli O157:H7 gut colonization. Given that E. coli O157:H...

journal_title：Infection and immunity

authors： Xue Y,Zhang H,Wang H,Hu J,Du M,Zhu MJ

更新日期：2014-05-01 00:00:00

abstract：:Mycobacterium bovis BCG is widely used as a vaccine against tuberculosis (TB), despite its variable protective efficacy. Relatively little is known about the immune response profiles following BCG vaccination in relation to protection against TB. Here we tested whether BCG vaccination results in immune responses to Do...

journal_title：Infection and immunity

authors： Lin MY,Geluk A,Smith SG,Stewart AL,Friggen AH,Franken KL,Verduyn MJ,van Meijgaarden KE,Voskuil MI,Dockrell HM,Huygen K,Ottenhoff TH,Klein MR

更新日期：2007-07-01 00:00:00

abstract：:The intravascular trematode Schistosoma mansoni is a causative agent of schistosomiasis, a disease that constitutes a major health problem globally. In this study we cloned and characterized the schistosome tegumental phosphodiesterase SmNPP-5 and evaluated its role in parasite virulence. SmNPP-5 is a 52.5-kDa protein...

journal_title：Infection and immunity

authors： Bhardwaj R,Krautz-Peterson G,Da'dara A,Tzipori S,Skelly PJ

更新日期：2011-10-01 00:00:00

abstract：:Antimicrobial factors were analyzed in samples of whole saliva from 31 children, aged 0.8 to 3.8 years. When compared with the adult reference group, the children displayed similar levels of lysozyme, salivary peroxidase, and hypothiocyanite (OSCN-), whereas the amounts of immunoglobulins (isotypes A, G, and M), lacto...

journal_title：Infection and immunity

authors： Tenovuo J,Lehtonen OP,Aaltonen AS,Vilja P,Tuohimaa P

更新日期：1986-01-01 00:00:00

abstract：:Bacteria have evolved strategies to resist killing by antimicrobial peptides (APs), important effectors of innate immunity. The sap (sensitivity to antimicrobial peptides) operon confers resistance to AP-mediated killing of Salmonella. We have recently shown that sapA gene expression is upregulated in the middle ear i...

journal_title：Infection and immunity

authors： Mason KM,Munson RS Jr,Bakaletz LO

更新日期：2005-01-01 00:00:00

abstract：:The T-cell-stimulating activity of staphylococcal enterotoxin B (SEB) is an important factor in the pathogenesis of certain staphylococcal diseases. To investigate the immunologically active domains of the SEB molecule, we have produced truncated fragments of recombinant SEB by C-terminal and N-terminal deletions. The...

journal_title：Infection and immunity

authors： Metzroth B,Marx T,Linnig M,Fleischer B

更新日期：1993-06-01 00:00:00

abstract：:The typically recovered quantity of nontypeable Haemophilus influenzae (NTHi) bacteria in an ex vivo middle ear (ME) aspirate from the chinchilla model of experimental otitis media is insufficient for direct analysis of gene expression by microarray or of lipopolysaccharide glycoforms by mass spectrometry. This prompt...

journal_title：Infection and immunity

authors： Leroy M,Cabral H,Figueira M,Bouchet V,Huot H,Ram S,Pelton SI,Goldstein R

更新日期：2007-08-01 00:00:00

abstract：:Bovine septicemic Escherichia coli 31A agglutinates bovine, rabbit, and human erythrocytes and adheres in vitro to the brush border of bovine or ovine intestinal epithelial cells and to the human colon carcinoma Caco-2 cell line. The adhesion and hemagglutination of E. coli 31A are mediated by a chromosome-encoded fim...

journal_title：Infection and immunity

authors： Bertin Y,Girardeau JP,Darfeuille-Michaud A,Contrepois M

更新日期：1996-01-01 00:00:00

abstract：:Deciphering the mechanisms by which Borrelia burgdorferi controls the synthesis of proteins associated with mammalian infection will be an important step toward understanding the pathogenic properties of Lyme disease-causing bacteria. We present results of studies indicating that B. burgdorferi senses a wide variety o...

journal_title：Infection and immunity

authors： Babb K,El-Hage N,Miller JC,Carroll JA,Stevenson B

更新日期：2001-06-01 00:00:00

abstract：:It was shown that a strain of Serratia liquefaciens harbors a conjugative R-plasmid responsible for reistance to the following 14 antibiotics: ampicillin, carbenicillin, cephalothin, butirosin, neomycin, paramomycin, kanamycin, lividomycin, gentamicin, tobramycin, streptomycin, tetracycline, sulfonamide, and chloramph...

journal_title：Infection and immunity

authors： Duval-Iflah Y,Raibaud P,Tancrede C,Rousseau M

更新日期：1980-06-01 00:00:00

abstract：:Phagocytosis of unopsonized Salmonella typhimurium 395, MR-10, opsonized Salmonella typhimurium 395 MS, and Staphylococcus epidermidis by rabbit polymorphonuclear leukocytes was inhibited by heparin at concentrations as low as 0.5 U/ml. Inhibition was dose dependent and nearly complete at 20 U/ml. Provided that hepari...

journal_title：Infection and immunity

authors： Victor M,Weiss J,Elsbach P

更新日期：1981-04-01 00:00:00

abstract：:Coxiella burnetii, phase I and II, cells cultivated in the yolk sac of chicken embryos were separated from host cell components by two cycles of isopycnic Renografin gradient centrifugation. Initial steps in the purification of viable C. burnetii involved differential centrifugation and sedimentation through an aqueou...

journal_title：Infection and immunity

authors： Williams JC,Peacock MG,McCaul TF

更新日期：1981-05-01 00:00:00

abstract：:Mouse peritoneal macrophages were infected with varying numbers of Nocardia asteroides 10905, and the fate of the ingested organisms was determined by viable plate count (VPC), light microscopy (LM), immunofluorescent microscopy (IM), and electron microscopy (EM). The results obtained with these methods differed. VPC ...

journal_title：Infection and immunity

authors： Bourgeois L,Beaman BL

更新日期：1974-03-01 00:00:00

abstract：:Polymorphonuclear leukocytes (PMN) from patients with chronic granulomatous disease (CGD) fail to produce microbicidal concentrations of reactive oxygen species (ROS) due to mutations in NOX2. Patients with CGD suffer from severe, life-threatening infections and inflammatory complications. Granulibacter bethesdensis i...

journal_title：Infection and immunity

authors： Greenberg DE,Sturdevant DE,Marshall-Batty KR,Chu J,Pettinato AM,Virtaneva K,Lane J,Geller BL,Porcella SF,Gallin JI,Holland SM,Zarember KA

更新日期：2015-11-01 00:00:00

abstract：:Mice were protected against a lethal infection with Listeria monocytogenes when treated with low doses of an anti-CD3 monoclonal antibody (MAb). Injection of anti-CD3 MAb induced rapid production of endogenous tumor necrosis factor (TNF) in the spleens and endogenous gamma interferon (IFN-gamma) in the bloodstreams an...

journal_title：Infection and immunity

authors： Nakane A,Okamoto M,Asano M,Kohanawa M,Minagawa T

更新日期：1993-07-01 00:00:00

abstract：:Elevated levels of immunoglobulin E anti-Candida antibodies were observed in the sera of patients with systemic and vaginal candidiasis and in cervicovaginal washings of the latter. ...

journal_title：Infection and immunity

authors： Mathur S,Goust JM,Horger EO 3rd,Fudenberg HH

更新日期：1977-10-01 00:00:00

abstract：:Biomaterial-associated infections (BAI), which are predominantly caused by Staphylococcus epidermidis, are a significant problem in modern medicine. Biofilm formation is considered the pivotal element in the pathogenesis, but in previous mouse studies we retrieved S. epidermidis from peri-implant tissue. To assess the...

journal_title：Infection and immunity

authors： Broekhuizen CA,de Boer L,Schipper K,Jones CD,Quadir S,Feldman RG,Dankert J,Vandenbroucke-Grauls CM,Weening JJ,Zaat SA

更新日期：2007-03-01 00:00:00

abstract：:Campylobacter jejuni is a major cause of human inflammatory enteritis. During the course of human disease numerous proinflammatory cytokines are produced. Little is known, however, about the cytokine responses produced during the interaction of this bacterium with the avian host. Campylobacter has been considered a co...

journal_title：Infection and immunity

authors： Smith CK,Kaiser P,Rothwell L,Humphrey T,Barrow PA,Jones MA

更新日期：2005-04-01 00:00:00

abstract：:Monoclonal antibodies (TpM 3, TpM 6, and TpM 19) against Toxoplasma gondii insoluble antigens were produced by the hybridization of NS-1, a mouse myeloma cell line, with spleen cells from mice immunized with T. gondii insoluble antigens. TpM 3, TpM 6, and TpM 19 were characterized by the dye test, the latex agglutinat...

journal_title：Infection and immunity

authors： Ogata K,Kasahara T,Shioiri-Nakano K,Igarashi I,Suzuki M

更新日期：1984-03-01 00:00:00

abstract：:The immune response of mice to live, heat-killed, or autoclaved Mycobacterium leprae was investigated. After sensitization with 10(7) organisms in each group, recipient mice were transfused with the sensitized splenocytes 28 days later. A selected number of these mice were infected with 5 X 10(3) M. leprae, and the re...

journal_title：Infection and immunity

authors： Graham L Jr,Navalkar RG

更新日期：1984-01-01 00:00:00

abstract：:Borrelias that cause Lyme disease lose the ability to infect and cause disease in laboratory animals following 10 to 16 passages of in vitro culture. In this study, clonal populations of the Sh-2-82 (Sh2) and B31 strains of Borrelia burgdorferi were isolated by subsurface plating on BSK-II agar plates and examined for...

journal_title：Infection and immunity

authors： Norris SJ,Howell JK,Garza SA,Ferdows MS,Barbour AG

更新日期：1995-06-01 00:00:00

abstract：:In pathogenic bacteria, iron acquisition is important for colonization and proliferation in the host under iron-limited conditions. The ability of Vibrio spp. to acquire iron is often critical to their virulence, causing gastroenteritis or excessive watery diarrhea in humans. In the study described here, we cloned the...

journal_title：Infection and immunity

authors： Ahn SH,Han JH,Lee JH,Park KJ,Kong IS

更新日期：2005-02-01 00:00:00

abstract：:Lesions caused by Leishmania amazonensis normally heal, but relapses occur due to parasite persistence in host tissues. It has been proposed that infection of fibroblasts plays an important role in this process by providing the parasites with a safe haven in which to replicate. However, most previous studies have focu...

journal_title：Infection and immunity

authors： Morehead J,Coppens I,Andrews NW

更新日期：2002-08-01 00:00:00

abstract：:The complement system plays a key role in resistance to cryptococcosis. In the present study, we examined several factors that influence the binding of C3 cleavage fragments to Cryptococcus neoformans. Binding of C3 was determined by using normal human serum supplemented with 125I-labeled C3. Incubation of encapsulate...

journal_title：Infection and immunity

authors： Kozel TR,Pfrommer GS

更新日期：1986-04-01 00:00:00

abstract：:Enterotoxigenic Escherichia coli (ETEC) is a major cause of traveler's diarrhea as well as of endemic diarrhea and stunting in children in developing areas. However, a small-mammal model has been badly needed to better understand and assess mechanisms, vaccines, and interventions. We report a murine model of ETEC diar...

journal_title：Infection and immunity

authors： Bolick DT,Medeiros PHQS,Ledwaba SE,Lima AAM,Nataro JP,Barry EM,Guerrant RL

更新日期：2018-06-21 00:00:00

abstract：:Vesicular stomatitis virus (Indiana strain) will only grow in T lymphocytes which have been stimulated to undergo cell division. Evidence is presented that a considerable enrichment of the vesicular stomatitis virus-replicating T cells may be accomplished in the mouse spleen by passing the spleen cells over glass wool...

journal_title：Infection and immunity

authors： Webb DR,Munshi S,Banerjee AK

更新日期：1981-04-01 00:00:00

abstract：:Studies of mice suggest that pneumococcal proteins, including PspA, pneumolysin, PsaA, and CbpA, are promising vaccine candidates. To determine whether these proteins are good mucosal immunogens in humans, adenoidal lymphocytes from 20 children who had adenoidectomies were isolated and tested by ELISpot for antigen-sp...

journal_title：Infection and immunity

authors： Zhang Q,Choo S,Finn A

更新日期：2002-10-01 00:00:00

abstract：:Immune responses of mice to Streptococcus mutans serotype c were analyzed by means of the enzyme-linked immunospot assay to determine the predominant specificities of the antibodies developed. In general, the numbers of splenic antibody-secreting cells correlated with serum antibody levels. A low dose (10(8) CFU) of k...

journal_title：Infection and immunity

authors： Russell MW,Czerkinsky C,Moldoveanu Z

更新日期：1986-08-01 00:00:00

abstract：:We have previously shown that Bacillus anthracis lethal toxin represses glucocorticoid receptor (GR) transactivation. We now report that repression of GR activity also occurs with the large clostridial toxins produced by Clostridium sordellii and C. difficile. This was demonstrated using a transient transfection assay...

journal_title：Infection and immunity

authors： Tait AS,Dalton M,Geny B,D'Agnillo F,Popoff MR,Sternberg EM

更新日期：2007-08-01 00:00:00

abstract：:Bordetella pertussis fimbriae are composed of a major subunit, Fim2 or Fim3, and the minor subunit FimD. Using immunoelectron microscopy, we provide evidence that FimD is located at the fimbrial tip. The role of FimD in colonization of the mouse respiratory tract was studied by using two fimbrial mutants: a mutant com...

journal_title：Infection and immunity

authors： Geuijen CA,Willems RJ,Bongaerts M,Top J,Gielen H,Mooi FR

更新日期：1997-10-01 00:00:00