Adhesion molecule deficiencies increase Porphyromonas gingivalis-induced alveolar bone loss in mice.

abstract：:We examined the association of Herpesvirus saimiri with lymphocyte subsets and the functional integrity and distribution of these populations in owl monkeys with chronic, disease-free infections, in uninoculated, control animals, and in one monkey with H. saimiri-induced lymphoma. The lymphocyte subpopulations examine...

journal_title：Infection and immunity

authors： Neubauer RH,Dunn FE,Rabin H

更新日期：1981-05-01 00:00:00

abstract：:The affinity of uropathogenic Escherichia coli to kidneys and bladders of experimentally infected mice was shown to be determined in part by the adhesive properties of the infecting bacteria. Mice were infected with various pairwise combinations of two homogeneic sets of bacteria: (i) mutants derived from a human pyel...

journal_title：Infection and immunity

authors： Hagberg L,Hull R,Hull S,Falkow S,Freter R,Svanborg Edén C

更新日期：1983-04-01 00:00:00

abstract：:Mucosal immune responses to fungal infection range from T helper type 2 (Th2) cell-directed allergic inflammation to Th1-predominant neutrophilic inflammation, but the mechanisms directing these divergent mucosal immune outcomes and the role of T cells in host defense against mucosal fungal infections are not known. H...

journal_title：Infection and immunity

authors： Porter PC,Roberts L,Fields A,Knight M,Qian Y,Delclos GL,Han S,Kheradmand F,Corry DB

更新日期：2011-11-01 00:00:00

abstract：:Previous examination of thin sections of L929 cells heavily infected with the Q fever Priscilla isolate by conventional transmission electron microscopy indicated that the rickettsiae resided within multiple vacuoles. The present study using high-voltage electron microscopy and three-dimensional reconstruction reveale...

journal_title：Infection and immunity

authors： Hechemy KE,McKee M,Marko M,Samsonoff WA,Roman M,Baca O

更新日期：1993-10-01 00:00:00

abstract：:Ribosomes of strain NOR-7 of group B Neisseria meningitidis were isolated by a procedure that included treatment of the cells with sodium dodecyl sulfate, disruption in a French pressure cell, and differential centrifugation. These preparations consisted of 66% ribonucleic acid and 24% protein and sedimented as a sing...

journal_title：Infection and immunity

authors： Thomas DW,Weiss E

更新日期：1972-09-01 00:00:00

abstract：:The microbicidal myeloperoxidase (MPO)-H2O2-chloride system strongly inhibits Escherichia coli DNA synthesis. Also, cell envelopes from MPO-treated E. coli cells lose their ability to interact with hemimethylated DNA sequences of oriC, the chromosomal origin of replication, raising the prospect that suppression of DNA...

journal_title：Infection and immunity

authors： Rosen H,Michel BR,vanDevanter DR,Hughes JP

更新日期：1998-06-01 00:00:00

abstract：:High levels of Treponema denticola in subgingival dental plaque are associated with severe periodontal disease. T. denticola, along with Porphyromonas gingivalis and Bacteroides forsythus, are the only cultivatable oral microorganisms that produce significant amounts of "trypsin-like" peptidase activity. The ability o...

journal_title：Infection and immunity

authors： Fenno JC,Lee SY,Bayer CH,Ning Y

更新日期：2001-10-01 00:00:00

abstract：:Bordetella bronchiseptica secreted a hydroxamate siderophore when grown in Fe-depleted medium. A Tn5lac insertion mutant of B. bronchiseptica, DBB22, did not produce this hydroxamate siderophore and was incapable of using lactoferrin as an Fe source. Our data suggest that B. bronchiseptica uses a siderophore for remov...

journal_title：Infection and immunity

authors： Foster LA,Dyer DW

更新日期：1993-06-01 00:00:00

abstract：:Using the enteropathogenic Escherichia coli (EPEC) genome sequence, we found that EPEC E2348/69 has an lpfABCDE gene cluster homologous (about 60% identical at the protein level) to the Salmonella long polar fimbria (LPF) operon. To determine whether this operon is essential for adherence, the lpfABCD(E2)(3) genes wer...

journal_title：Infection and immunity

authors： Tatsuno I,Mundy R,Frankel G,Chong Y,Phillips AD,Torres AG,Kaper JB

更新日期：2006-01-01 00:00:00

abstract：:Rabbit lymphoid cells from spleen, peripheral blood, and peritoneal cavity lacked killer (K)-cell activity against cell lines of rabbit and human origin, including virus-infected human tumor cells. This lack of activity was not affected by antibody concentration, source of antibodies, effector/target cell ratio, or le...

journal_title：Infection and immunity

authors： Karavodin LM,Sidell N,Woan MC,Tompkins WA

更新日期：1982-02-01 00:00:00

abstract：:Bovine mastitis continues to be the most detrimental factor for profitable dairying. Recent research conducted within our laboratory has identified a genetic marker in the CXCR2 gene associated with mastitis susceptibility. The objective of the present study was to evaluate the migratory ability of neutrophils from co...

journal_title：Infection and immunity

authors： Rambeaud M,Pighetti GM

更新日期：2005-08-01 00:00:00

abstract：:Proteus mirabilis, a common agent of nosocomially acquired and catheter-associated urinary tract infection, is the most frequent cause of infection-induced bladder and kidney stones. Urease-catalyzed urea hydrolysis initiates stone formation in urine and can be inhibited by acetohydroxamic acid and other structural an...

journal_title：Infection and immunity

authors： Nicholson EB,Concaugh EA,Mobley HL

更新日期：1991-10-01 00:00:00

abstract：:The smooth lipopolysaccharide complex of the outer surface of smooth Brucella abortus cells is believed to be the antigenic component involved in serological tests routinely used for the diagnosis of brucellosis. Sera from cattle vaccinated or infected with B. abortus generally contain antibody directed toward the smo...

journal_title：Infection and immunity

authors： Schurig GG,Jones LM,Speth SL,Berman DT

更新日期：1978-09-01 00:00:00

abstract：:Borrelia burgdorferi, a causative agent of Lyme borreliosis, is a zoonotic pathogen that survives in nutrient-limited environments within a tick, prior to transmission to its mammalian host. Survival under these prolonged nutrient-limited conditions is thought to be similar to survival during stationary phase, which i...

journal_title：Infection and immunity

authors： Fazzino L,Tilly K,Dulebohn DP,Rosa PA

更新日期：2015-12-01 00:00:00

abstract：:To evaluate the enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides, the rate of isolation of these organisms was compared among individuals with and without diarrhea in Thailand. In two groups of American travelers, A. hydrophila, but not P. shigelloides, was associated with episodes of travelers...

journal_title：Infection and immunity

authors： Pitarangsi C,Echeverria P,Whitmire R,Tirapat C,Formal S,Dammin GJ,Tingtalapong M

更新日期：1982-02-01 00:00:00

abstract：:A monoclonal immunoglobulin M antibody, HP15/36, was produced by a hybridoma cell line prepared by fusion of mouse myeloma cell line Sp2/O with spleen cells of mice immunized with Helicobacter pylori D273 (French strain). Immunoelectron microscopy of whole bacteria and ultrathin sections showed that the determinant wa...

journal_title：Infection and immunity

authors： Drouet EB,De Montclos HP,Andujar M,Boude M,Grimaud JA,Denoyel GA

更新日期：1993-06-01 00:00:00

abstract：:The role of gamma-delta T cells in host resistance to Chlamydia trachomatis was characterized by using a murine model of pneumonia caused by the mouse pneumonitis agent (MoPn), murine C. trachomatis. At days 3 and 7 after infection, gamma-delta T-cell-deficient knockout mice had significantly higher levels of MoPn in ...

journal_title：Infection and immunity

authors： Williams DM,Grubbs BG,Kelly K,Pack E,Rank RG

更新日期：1996-09-01 00:00:00

abstract：:Using pharmacologic and biochemical criteria, we evaluated whether uptake of four different Chlamydia trachomatis serovars, D, E, K, and L2, was dependent upon lipid rafts. Our data suggest that lipid raft-mediated entry is not required for C. trachomatis infection of cultured epithelial cells. ...

journal_title：Infection and immunity

authors： Gabel BR,Elwell C,van Ijzendoorn SC,Engel JN

更新日期：2004-12-01 00:00:00

abstract：:Previously, we identified five genes (Cj1321 to Cj1326, of which Cj1325 and Cj1326 are a single gene) in the O-linked flagellin glycosylation island that are highly prevalent in Campylobacter jejuni isolates from chickens. We report mutagenesis, functional, and structural data to confirm that this locus, and Cj1324 in...

journal_title：Infection and immunity

authors： Howard SL,Jagannathan A,Soo EC,Hui JP,Aubry AJ,Ahmed I,Karlyshev A,Kelly JF,Jones MA,Stevens MP,Logan SM,Wren BW

更新日期：2009-06-01 00:00:00

abstract：:The relationship between hypersensitivity and cellular resistance to infection with facultative intracellular parasites was studied in mice by using infection-immunity in tularemia as a model system. Delayed hypersensitivity to antigenic fractions of Francisella tularensis was first detected 6 to 7 days after immuniza...

journal_title：Infection and immunity

authors： Claflin JL,Larson CL

更新日期：1972-03-01 00:00:00

abstract：:Neutrophil serine proteases cathepsin G (CG), neutrophil elastase (NE), and proteinase 3 (PR3) have recently been shown to contribute to killing of Streptococcus pneumoniae in vitro. However, their relevance in lung-protective immunity against different serotypes of S. pneumoniae in vivo has not been determined so far...

journal_title：Infection and immunity

authors： Hahn I,Klaus A,Janze AK,Steinwede K,Ding N,Bohling J,Brumshagen C,Serrano H,Gauthier F,Paton JC,Welte T,Maus UA

更新日期：2011-12-01 00:00:00

abstract：:Transcription of the gene encoding the antiphagocytic M protein (emm) of the group A streptococci has been shown to be regulated by CO2 (M. G. Caparon, R. T. Geist, J. Perez-Casal, and J. R. Scott, J. Bacteriol. 174:5693-5701, 1992). We tested the influence of additional environmental growth conditions on emm expressi...

journal_title：Infection and immunity

authors： McIver KS,Heath AS,Scott JR

更新日期：1995-11-01 00:00:00

abstract：:Erythrocytic malaria parasites degrade hemoglobin as a principal source of amino acids for parasite protein synthesis. We have previously shown that a Plasmodium falciparum trophozoite cysteine proteinase, now termed falcipain, is required for hemoglobin degradation, and we have hypothesized that this proteinase is re...

journal_title：Infection and immunity

authors： Salas F,Fichmann J,Lee GK,Scott MD,Rosenthal PJ

更新日期：1995-06-01 00:00:00

abstract：:An acute and persistent eosinophil infiltration is observed during Mycobacterium bovis BCG pleural infection in mice. Eosinophil accumulation, lipid body formation, and eotaxin production were significantly reduced in BCG-infected Toll-like receptor-2 (TLR2)-deficient mice compared to wild-type mice. Neutralization of...

journal_title：Infection and immunity

authors： D'Avila H,Almeida PE,Roque NR,Castro-Faria-Neto HC,Bozza PT

更新日期：2007-03-01 00:00:00

abstract：:Resistance to cutaneous syphilitic reinfection in strain 2 and strain 13 guinea pigs developed gradually 3 to 7 months after primary infection and reached maximum levels at 6 to 7 months after the induction of primary cutaneous disease. Associated with this acquired resistance was the occurrence of Arthus reactions an...

journal_title：Infection and immunity

authors： Pavia CS,Niederbuhl CJ

更新日期：1985-10-01 00:00:00

abstract：:We have previously shown that infection by Trypanosoma cruzi, a parasitic protozoan, is reduced by injection of CD40 ligand (CD40L)-transfected 3T3 fibroblasts (D. Chaussabel, F. Jacobs, J. de Jonge, M. de Veerman, Y. Carlier, K. Thielemans, M. Goldman, and B. Vray, Infect. Immun. 67:1929-1934, 1999). This prompted us...

journal_title：Infection and immunity

authors： Chamekh M,Vercruysse V,Habib M,Lorent M,Goldman M,Allaoui A,Vray B

更新日期：2005-10-01 00:00:00

abstract：:Staphylococcus aureus is a pathogen often found in pneumonia and sepsis. In the context of the resistance of this organism to conventional antibiotics, an understanding of the regulation of natural endogenous antimicrobial molecules is of paramount importance. Previous studies have shown that both human and mouse airw...

journal_title：Infection and immunity

authors： McMichael JW,Maxwell AI,Hayashi K,Taylor K,Wallace WA,Govan JR,Dorin JR,Sallenave JM

更新日期：2005-06-01 00:00:00

abstract：:Bordetella pertussis extract that contained adenylate cyclase toxin produced large increases in human neutrophil cyclic AMP levels and inhibited their oxidative burst, as reflected by luminol-enhanced chemiluminescence and superoxide release. The adenylate cyclase toxin-containing extract blocked neutrophil-mediated i...

journal_title：Infection and immunity

authors： Galgiani JN,Hewlett EL,Friedman RL

更新日期：1988-04-01 00:00:00

abstract：:Previous studies have suggested that interleukin-4 (IL-4) has a protective effect in host defense to Borrelia burgdorferi infection, both in limiting the severity of arthritis and in controlling spirochete numbers in tissues, and a mapping study revealed suggestive linkage to a cluster of genes on mouse chromosome 11,...

journal_title：Infection and immunity

authors： Potter MR,Noben-Trauth N,Weis JH,Teuscher C,Weis JJ

更新日期：2000-10-01 00:00:00

abstract：:In an effort to relate the protein profile to virulence, proteins from the cellular fractions and from culture supernatants of Streptococcus suis capsular type 2 strains from different geographical origins were compared by using Western blots (immunoblots). The protein profiles of the cellular fractions were similar f...

journal_title：Infection and immunity

authors： Quessy S,Dubreuil JD,Caya M,Higgins R

更新日期：1995-05-01 00:00:00