Antibody response to antigens distinct from smooth lipopolysaccharide complex in Brucella infection.

abstract：:Two hybrid clones producing monoclonal antibodies (MAbs) raised against the purified enterotoxic hemolysin-phospholipase C (HlyPC) bifunctional molecule of a Vibrio cholerae O139 strain were used to study its enterotoxicity in relation to its hemolytic and enzymatic activities. Fab fragments of MAbs from ascites produ...

journal_title：Infection and immunity

authors： Pal S,Datta A,Nair GB,Guhathakurta B

更新日期：1998-08-01 00:00:00

abstract：:The genetic determinants of the 120-kDa cytotoxin of Actinobacillus pleuropneumoniae serotype 2 were isolated from a lambda DNA library by a plaque immunoblot technique. Expression of the 120-kDa polypeptide was confirmed by Western immunoblot analysis of infected Escherichia coli cell lysates, which were shown to be ...

journal_title：Infection and immunity

authors： MacDonald J,Rycroft AN

更新日期：1992-07-01 00:00:00

abstract：:The urease gene of Staphylococcus saprophyticus CCM883 was cloned and expressed in Staphylococcus carnosus TM300. In vitro translation of the cloned DNA sequences revealed six polypeptides (of 70, 47, 29, 27, 20, and 17 kilodaltons) that were associated with enzyme activity. Introduction of the cloned genes into a ure...

journal_title：Infection and immunity

authors： Gatermann S,Marre R

更新日期：1989-10-01 00:00:00

abstract：:Neisseria meningitidis crosses the blood-brain barrier (BBB) following the activation of the β2-adrenergic receptor by the type IV pili (TFP). Two components of the type IV pili recruit the β2-adrenergic receptor, the major pilin PilE and the minor pilin PilV. Here, we report that a strain deleted of PilX, one of the ...

journal_title：Infection and immunity

authors： Brissac T,Mikaty G,Duménil G,Coureuil M,Nassif X

更新日期：2012-09-01 00:00:00

abstract：:Rickettsia rickettsii and R. australis formed infectious antibody complexes when reacted with homologous convalescent serum. The addition of antiglobulin to these complexes showed neutralization of plaques proportional to the concentration of rickettsial immune serum. ...

journal_title：Infection and immunity

authors： Kenyon RH,McManus AT

更新日期：1974-05-01 00:00:00

abstract：:Entamoeba histolytica and its reptilian counterpart and encystation model Entamoeba invadens formed a polarized monopodial morphology when treated with pentoxifylline. This morphology was propelled by retrograde flow of the cell surface resulting from a cyclic sol-gel conversion of cytoplasm and a stable bleb at the l...

journal_title：Infection and immunity

authors： Krishnan D,Ghosh SK

更新日期：2020-07-21 00:00:00

abstract：:The Haemophilus ducreyi 35000HP genome encodes a homolog of the CpxRA two-component cell envelope stress response system originally characterized in Escherichia coli. CpxR, the cytoplasmic response regulator, was shown previously to be involved in repression of the expression of the lspB-lspA2 operon (M. Labandeira-Re...

journal_title：Infection and immunity

authors： Labandeira-Rey M,Brautigam CA,Hansen EJ

更新日期：2010-11-01 00:00:00

abstract：:Secretory immunoglobulin A (SIgA) antibodies directed against the O antigen of lipopolysaccharide (LPS) are the primary determinants of mucosal immunity to gram-negative enteric pathogens. However, the underlying mechanisms by which these antibodies interfere with bacterial colonization and invasion of intestinal epit...

journal_title：Infection and immunity

authors： Forbes SJ,Eschmann M,Mantis NJ

更新日期：2008-09-01 00:00:00

abstract：:Piliated Burkholderia (formerly Pseudomonas) cepacia from sputa of cys tic fibrosis patients in Toronto, Canada, were shown earlier to bind to purified mucins and to a protein receptor on epithelial cells via a 22-kDa adhesin located on unique cable pili. However, a second receptor, thought to be lipid in nature, was ...

journal_title：Infection and immunity

authors： Sylvester FA,Sajjan US,Forstner JF

更新日期：1996-04-01 00:00:00

abstract：:The Burkholderia cepacia epidemic strain marker (BCESM) is a useful epidemiological marker for virulent B. cenocepacia strains that infect patients with cystic fibrosis. However, there was no evidence that the original marker, identified by random amplified polymorphic DNA fingerprinting, contributed to pathogenicity....

journal_title：Infection and immunity

authors： Baldwin A,Sokol PA,Parkhill J,Mahenthiralingam E

更新日期：2004-03-01 00:00:00

abstract：:Recognition of microbial patterns by host receptors is the first step in a multistep sequence leading to neutrophil-dependent host resistance. Although the role of membrane-bound sensors in bacterial recognition has been examined in detail, the importance of cytosolic sensors in the lungs is largely unexplored. In thi...

journal_title：Infection and immunity

authors： Balamayooran T,Batra S,Balamayooran G,Cai S,Kobayashi KS,Flavell RA,Jeyaseelan S

更新日期：2011-11-01 00:00:00

abstract：:Escherichia coli O157:H7 causes food and waterborne enteric infections that can result in hemorrhagic colitis and life-threatening hemolytic uremic syndrome. Intimate adherence of the bacteria to intestinal epithelial cells is mediated by intimin, but E. coli O157:H7 also possess several other putative adhesins, inclu...

journal_title：Infection and immunity

authors： Lloyd SJ,Ritchie JM,Rojas-Lopez M,Blumentritt CA,Popov VL,Greenwich JL,Waldor MK,Torres AG

更新日期：2012-03-01 00:00:00

abstract：:Porphyromonas gingivalis is reportedly capable of stimulating the expression of host cell matrix metalloproteinases (MMP), contributing to tissue destruction. However, the impact of this bacterium on specific molecules remains to be determined. In this study, we evaluate the effect of P. gingivalis on regulation of MM...

journal_title：Infection and immunity

authors： Fravalo P,Ménard C,Bonnaure-Mallet M

更新日期：1996-12-01 00:00:00

abstract：:The interaction of plasma fibronectin with C1q of the complement system has been demonstrated in the past several years. In addition, the antibody-independent binding of C1q to bacteria, as well as the binding of plasma fibronectin to bacteria, is well documented. This study examines whether the binding of C1q to bact...

journal_title：Infection and immunity

authors： Sorvillo JM,Pearlstein E

更新日期：1985-09-01 00:00:00

abstract：:The coagulase-negative species Staphylococcus lugdunensis is an emerging cause of serious and potentially life-threatening infections, such as infective endocarditis. The pathogenesis of these infections is characterized by the ability of S. lugdunensis to form biofilms on either biotic or abiotic surfaces. To elucida...

journal_title：Infection and immunity

authors： Rajendran NB,Eikmeier J,Becker K,Hussain M,Peters G,Heilmann C

更新日期：2015-12-01 00:00:00

abstract：:We have cloned chromosomal genes mediating the aerobactin iron transport system from the enteroinvasive strain Escherichia coli 978-77. The physical map of the region spanning the siderophore biosynthesis genes and the upstream portion of the receptor gene in strain 978-77-derived clones was identical to the correspon...

journal_title：Infection and immunity

authors： Marolda CL,Valvano MA,Crosa JH

更新日期：1991-01-01 00:00:00

abstract：:Mice pretreated intraperitoneally with trehalose-6,6'-dimycolate (cord factor) were protected against an intraperitoneal challenge with Salmonella typhi strain Ty2 or Salmonella typhimurium strain SR 11. The nonspecific resistance to S. typhi and S. typhimurium was still detectable 7 and 14 days, respectively, after a...

journal_title：Infection and immunity

authors： Yarkoni E,Bekierkunst A

更新日期：1976-11-01 00:00:00

abstract：:The adherence of Candida species yeast cells to bovine and human endothelium was measured. The adherence phenomenon is a saturable event which can be altered by the release of prostaglandin I2 (PGI2 or prostacyclin) by endothelial cells. Release of PGI2 by endothelium has a protective effect, reducing Candida albicans...

journal_title：Infection and immunity

authors： Klotz SA

更新日期：1994-04-01 00:00:00

abstract：:It is proposed that binding of oral streptococci to saliva-coated hydroxylapatite (SHA) surfaces is a multifactorial process involving both specific and nonspecific receptors. In this context, specific binding is described as a high-affinity, saturable interaction between the cell and binding surface. Conversely, nons...

journal_title：Infection and immunity

authors： Staat RH,Peyton JC

更新日期：1984-06-01 00:00:00

abstract：:Inactivated Marek's disease virus-infected chicken kidney cells and inactivated MSB-1 lymphoblastoid Marek's disease tumor cells were used to immunize chickens as virus- and tumor-associated antigens, respectively. Immune and nonimmune birds were then challenged by exposure to live virulent Marek's disease virus. Both...

journal_title：Infection and immunity

authors： Murthy KK,Calnek BW

更新日期：1979-11-01 00:00:00

abstract：:In the last few years, the great impact of antimicrobial peptides on infectious disease susceptibility and natural resistance has been reported. In some cases, susceptibility to diseases is related to antimicrobial peptide polymorphisms and gene copy numbers, but for the vast majority of infectious diseases, these phe...

journal_title：Infection and immunity

authors： Rivas-Santiago B,Serrano CJ,Enciso-Moreno JA

更新日期：2009-11-01 00:00:00

abstract：:The innate immune response in human tuberculosis is not completely understood. To improve our knowledge regarding the role of cathelicidin hCAP-18/LL37 in the innate immune response to tuberculosis infection, we used immunohistochemistry, immunoelectron microscopy, and gene expression to study the induction and produc...

journal_title：Infection and immunity

authors： Rivas-Santiago B,Hernandez-Pando R,Carranza C,Juarez E,Contreras JL,Aguilar-Leon D,Torres M,Sada E

更新日期：2008-03-01 00:00:00

abstract：:Increased incidence of bovine tuberculosis (TB) in the United Kingdom caused by infection with Mycobacterium bovis is a cause of considerable economic loss to farmers and the government. The Eurasian badger (Meles meles) represents a wildlife source of recurrent M. bovis infections of cattle in the United Kingdom, and...

journal_title：Infection and immunity

authors： Clark S,Cross ML,Nadian A,Vipond J,Court P,Williams A,Hewinson RG,Aldwell FE,Chambers MA

更新日期：2008-08-01 00:00:00

abstract：:In an attempt to understand the mechanism of serum resistance in Actinobacillus pleuropneumoniae, in the present study we examined various interactions among the bacterial surface constituents, serum antibodies, and complement. Analysis of swine sera revealed the presence of anticapsular antibodies in convalescent-pha...

journal_title：Infection and immunity

authors： Udeze FA,Kadis S

更新日期：1992-09-01 00:00:00

abstract：:Escherichia coli O157:H7 carries a chromosomal msbB1 and a plasmid-encoded msbB2 gene. We characterized msbB2 function as a homologue of msbB1 by examination of wild-type organisms and mutant strains that lacked functional msbB1, msbB2, and both msbB1 and msbB2. The msbB double-mutant strain generated pentaacyl lipid ...

journal_title：Infection and immunity

authors： Kim SH,Jia W,Bishop RE,Gyles C

更新日期：2004-02-01 00:00:00

abstract：:Our knowledge of pathogenesis has benefited from a better understanding of the roles of specific virulence factors in disease. To determine the role of the virulence factor ZapA, a 54-kDa metalloproteinase of Proteus mirabilis, in prostatitis, rats were infected with either wild-type (WT) P. mirabilis or its isogenic ...

journal_title：Infection and immunity

authors： Phan V,Belas R,Gilmore BF,Ceri H

更新日期：2008-11-01 00:00:00

abstract：:Host resistance to African trypanosomiasis is partially dependent on an early and strong T-independent B-cell response against the variant surface glycoprotein (VSG) coat expressed by trypanosomes. The repetitive array of surface epitopes displayed by a monotypic surface coat, in which identical VSG molecules are clos...

journal_title：Infection and immunity

authors： Dubois ME,Demick KP,Mansfield JM

更新日期：2005-05-01 00:00:00

abstract：:The hallmarks of pulmonary Mycobacterium tuberculosis infection are lung granulomas. These organized structures are composed of host immune cells whose purpose is to contain or clear infection, creating a complex hub of immune and bacterial cell activity, as well as limiting pathology in the lungs. Yet, given cellular...

journal_title：Infection and immunity

authors： Wong EA,Joslyn L,Grant NL,Klein E,Lin PL,Kirschner DE,Flynn JL

更新日期：2018-08-22 00:00:00

abstract：:Early-onset periodontitis (EOP) is characterized by rapidly progressive alveolar bone loss, chemotactic defects of neutrophils, and significant familial aggregation. We found immature myeloid lineage cells, defined as promyelocytes, in the peripheral blood in patients with EOP. A hematological examination of periphera...

journal_title：Infection and immunity

authors： Nemoto E,Nakamura M,Shoji S,Horiuchi H

更新日期：1997-09-01 00:00:00

abstract：:Quorum-sensing systems are critical regulators of the expression of virulence factors of various organisms, including Pseudomonas aeruginosa. Las and Rhl are two major quorum-sensing components, and they are regulated by their corresponding autoinducers, N-3-oxododecanoyl homoserine lactone (3-oxo-C(12)-HSL) and N-but...

journal_title：Infection and immunity

authors： Tateda K,Ishii Y,Horikawa M,Matsumoto T,Miyairi S,Pechere JC,Standiford TJ,Ishiguro M,Yamaguchi K

更新日期：2003-10-01 00:00:00