Important contribution of the novel locus comEB to extracellular DNA-dependent Staphylococcus lugdunensis biofilm formation.

abstract：:Sepsis and lipopolysaccharide (LPS) trigger the systemic release of both cytokines and catecholamines. Cytokines are known to be capable of eliciting a stress hormone response in vivo. The present study sought insight into the effect of noradrenaline on LPS-induced release of tumor necrosis factor alpha (TNF) and inte...

journal_title：Infection and immunity

authors： van der Poll T,Jansen J,Endert E,Sauerwein HP,van Deventer SJ

更新日期：1994-05-01 00:00:00

abstract：:Salmonella typhimurium SH5014 porins induce the release of tumor necrosis factor alpha (TNF-alpha), interleukin 1 alpha (IL-1 alpha), and IL-6 by human monocytes and of gamma interferon (IFN-gamma) and IL-4 by human lymphocytes. Porins at 1 microgram/ml induce the greatest release of TNF-alpha, IL-1 alpha, and IL-6 by...

journal_title：Infection and immunity

authors： Galdiero F,de L'ero GC,Benedetto N,Galdiero M,Tufano MA

更新日期：1993-01-01 00:00:00

abstract：:The effect of bile on the expression of cholera toxin (CT) and the major subunit of the toxin-coregulated pilus (TcpA) and on motility was examined in the Vibrio cholerae O1 classical-biotype strains 0395 and 569B. Although the motility of the cells increased significantly in the presence of bile, transcription of the...

journal_title：Infection and immunity

authors： Gupta S,Chowdhury R

更新日期：1997-03-01 00:00:00

abstract：:Killing of Salmonella minnesota and Salmonella typhimurium S and R strains in serum of nonimmune humans and guinea pigs was drastically reduced in the selective absence of C1q, C1r, Ca2+, C4, or C2, the components of the classical complement pathway. Binding of C1 and C1q to the S form and six different core-deficient...

journal_title：Infection and immunity

authors： Clas F,Loos M

更新日期：1982-09-01 00:00:00

abstract：:In this study, the role of the hepatobiliary system in the early pathogenesis of Salmonella enteritidis infection was investigated in a rat model. Intravenous (i.v.) challenge with lipopolysaccharide (LPS) has previously been shown to enhance the translocation of normal gut flora. We first confirmed that LPS can simil...

journal_title：Infection and immunity

authors： Islam AF,Moss ND,Dai Y,Smith MS,Collins AM,Jackson GD

更新日期：2000-01-01 00:00:00

abstract：:Chromatographic analysis, coupled to mass spectrometry with a high-resolution mass spectrometer, of materials isolated from skin lesions of patients with lepromatous leprosy allows the recognition of characteristic mycobacterial products, mycolic acids. This finding indicates that the "noncultivable" bacteria responsi...

journal_title：Infection and immunity

authors： Etemadi AH,Convit J

更新日期：1974-07-01 00:00:00

abstract：:3-O-methylmannose isolated from Coccidioides immitis was characterized by gas chromatographic comparison of derivatives with those of synthetic 3-O-methylmannose. Gas chromatographic behavior of three derivatives of the natural and synthetic sugars was identical. ...

journal_title：Infection and immunity

authors： Porter JF,Scheer ER,Wheat RW

更新日期：1971-11-01 00:00:00

abstract：:A murine model system was established to study immune responses to the Pnu-Imune vaccine, which is made up of 23 different pneumococcal capsular polysaccharides. In this animal model, antibody-forming cell responses to 21 of 23 individual polysaccharides in the vaccine were detected. The Pnu-Imune vaccine elicited goo...

journal_title：Infection and immunity

authors： Garg M,Subbarao B

更新日期：1992-06-01 00:00:00

abstract：:An attenuated Salmonella typhi Ty21a vaccine was administered to 18 infants and toddlers (less than or equal to 24 months old) to determine its safety and immunogenicity. The vaccination (10(9) CFU per dose, three doses) was well tolerated. However, after the vaccination there was no evidence of a humoral or cellular ...

journal_title：Infection and immunity

authors： Murphy JR,Grez L,Schlesinger L,Ferreccio C,Baqar S,Muñoz C,Wasserman SS,Losonsky G,Olson JG,Levine MM

更新日期：1991-11-01 00:00:00

abstract：:The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor involved in controlling several aspects of immune responses, including the activation and differentiation of specific T cell subsets and antigen-presenting cells, thought to be relevant in the context of experimental Trypanosoma cruzi infec...

journal_title：Infection and immunity

authors： Barroso A,Gualdrón-López M,Esper L,Brant F,Araújo RR,Carneiro MB,Ávila TV,Souza DG,Vieira LQ,Rachid MA,Tanowitz HB,Teixeira MM,Machado FS

更新日期：2016-09-19 00:00:00

abstract：:Antibodies to Escherichia coli O and K antigens were raised in rabbits by repeated immunizations with whole, Formalin-killed and, later, liver bacteria. The serum antibody levels were determined with the ammonium sulfate precipitation technique after radioiodinating the antigens. The K antigens had to be conjugated to...

journal_title：Infection and immunity

authors： Kaijser B,Ahlstedt S

更新日期：1977-08-01 00:00:00

abstract：:Legionella pneumophila is a bacterial pathogen that thrives in alveolar macrophages, causing a severe pneumonia. The virulence of L. pneumophila depends on its Dot/Icm type IV secretion system (T4SS), which delivers more than 300 effector proteins into the host, where they rewire cellular signaling to establish a repl...

journal_title：Infection and immunity

authors： Schroeder GN,Aurass P,Oates CV,Tate EW,Hartland EL,Flieger A,Frankel G

更新日期：2015-10-01 00:00:00

abstract：:During infection, the Legionnaires' disease bacterium, Legionella pneumophila, survives and multiplies within a specialized phagosome that is near neutral pH and does not fuse with host lysosomes. In order to understand the molecular basis of this organism's ability to control its intracellular fate, we have isolated ...

journal_title：Infection and immunity

authors： Wiater LA,Dunn K,Maxfield FR,Shuman HA

更新日期：1998-09-01 00:00:00

abstract：:The flavivirus dengue and the arenavirus Junin are both associated with a hemorrhagic shock syndrome in man. We have demonstrated the replication of these viruses in vitro in both rabbit and human endothelial cells by viral titers and immunofluorescent antibody studies. Rabbit endothelium established in continuous cul...

journal_title：Infection and immunity

authors： Andrews BS,Theofilopoulos AN,Peters CJ,Loskutoff DJ,Brandt WE,Dixon FJ

更新日期：1978-06-01 00:00:00

abstract：:Group A streptococci (GAS) are highly prevalent human pathogens whose primary ecological niche is the superficial epithelial layers of the throat and/or skin. Many GAS strains with a strong tendency to cause pharyngitis are distinct from strains that tend to cause impetigo; thus, genetic differences between them may c...

journal_title：Infection and immunity

authors： Rouchon CN,Ly AT,Noto JP,Luo F,Lizano S,Bessen DE

更新日期：2017-10-18 00:00:00

abstract：:Ocular inflammation is one of the consequences of infection with the protozoan parasite Toxoplasma gondii. Even if lesions are self-healing in immunocompetent persons, they pose a lifetime risk of reactivation and are a serious threat to vision. As there are virtually no immunological data on reactivating ocular toxop...

journal_title：Infection and immunity

authors： Rochet É,Brunet J,Sabou M,Marcellin L,Bourcier T,Candolfi E,Pfaff AW

更新日期：2015-05-01 00:00:00

abstract：:Experimental infection of mice with a virulent strain of Mycobacterium avium leads to a slowly progressive disease, which we have previously shown culminates in loss of gamma interferon (IFN-gamma) production by T lymphocytes and death of the animals approximately 40 weeks after infection. Here we investigated the cha...

journal_title：Infection and immunity

authors： Mannering SI,Cheers C

更新日期：2002-01-01 00:00:00

abstract：:Normal cell polarity protects epithelial cells against Pseudomonas aeruginosa invasion and cytotoxicity. Using epithelial cell clones with selective defects in sorting of membrane constituents, and using hepatocyte growth factor pretreatment, we found that polarized susceptibility to P. aeruginosa can be altered witho...

journal_title：Infection and immunity

authors： Fleiszig SM,Vallas V,Jun CH,Mok L,Balkovetz DF,Roth MG,Mostov KE

更新日期：1998-07-01 00:00:00

abstract：:Cell-mediated immune (CMI) responses and tumor necrosis factor alpha (TNF-alpha) have been shown to be essential in acquired protection against Cryptococcus neoformans. Induction of a protective anticryptococcal CMI response includes increases in dendritic cells (DC) and activated CD4(+) T cells in draining lymph node...

journal_title：Infection and immunity

authors： Bauman SK,Huffnagle GB,Murphy JW

更新日期：2003-01-01 00:00:00

abstract：:Cutaneous lesions of the human sexually transmitted genital ulcer disease chancroid are characterized by the presence of intraepidermal pustules, keratinocyte cytopathology, and epidermal and dermal erosion. These lesions are replete with neutrophils, macrophages, and CD4(+) T cells and contain very low numbers of cel...

journal_title：Infection and immunity

authors： San Mateo LR,Toffer KL,Orndorff PE,Kawula TH

更新日期：1999-09-01 00:00:00

abstract：:The ability of Toxoplasma gondii tachyzoites to differentiate into latent bradyzoite forms is essential for pathogenesis of clinical disease. We examined the effects of cyclic nucleotides on T. gondii bradyzoite differentiation in vitro. Differentiation of tachyzoites to bradyzoites was measured in an immunofluorescen...

journal_title：Infection and immunity

authors： Kirkman LA,Weiss LM,Kim K

更新日期：2001-01-01 00:00:00

abstract：:We examined the secretion of antimicrobial proteins and peptides into surgically isolated and continuously perfused segments of rat small intestine. Up to nine discrete antimicrobial molecules appeared in the intestinal perfusates following intravenous administration of bethanechol, a cholinergic agonist, or intralume...

journal_title：Infection and immunity

authors： Qu XD,Lloyd KC,Walsh JH,Lehrer RI

更新日期：1996-12-01 00:00:00

abstract：:Immunization of monkeys with the 82-kDa rhoptry protein (p82) of Plasmodium falciparum can protect them against a lethal blood stage challenge, and monoclonal antibodies to p82 inhibit parasite growth in vitro. The role that a p82-specific immune response might play in human immunity to the parasite is not known. To d...

journal_title：Infection and immunity

authors： Howard RF,Jensen JB,Franklin HL

更新日期：1993-07-01 00:00:00

abstract：:Vitamin E protects nonimmunized and immunized mice against fatal Diplococcus pneumoniae type I (DpI) infection. A dietary supplementation of 180 mg of dl-alpha-tocopheryl acetate per kg of diet increased survival of nonimmunized mice from 20 to 80% when challenged with 20 organisms, and of mice immunized with 0.5 ng o...

journal_title：Infection and immunity

authors： Heinzerling RH,Tengerdy RP,Wick LL,Lueker DC

更新日期：1974-12-01 00:00:00

abstract：:Pertussis toxin (PT), a virulence factor secreted by Bordetella pertussis, contributes to respiratory tract infection and disease caused by this pathogen. By comparing a wild-type (WT) B. pertussis strain to a mutant strain with an in-frame deletion of the ptx genes encoding PT (DeltaPT), we recently found that the la...

journal_title：Infection and immunity

authors： Carbonetti NH,Artamonova GV,Andreasen C,Dudley E,Mays RM,Worthington ZE

更新日期：2004-06-01 00:00:00

abstract：:Upon infection of a host, the pathogenic fungus Aspergillus fumigatus is attacked by the reactive oxygen species produced by phagocytic cells. Detoxification of hydrogen peroxide by catalases was proposed as a way to overcome this host response. A. fumigatus produces three active catalases; one is produced by conidia,...

journal_title：Infection and immunity

authors： Paris S,Wysong D,Debeaupuis JP,Shibuya K,Philippe B,Diamond RD,Latgé JP

更新日期：2003-06-01 00:00:00

abstract：:Cholera is an acute diarrheal disease that is caused by the gram-negative bacterium Vibrio cholerae. The low efficacy of currently available killed-whole-cell vaccines and the reactinogenicity coupled with potential reversion of live vaccines have thus far precluded widespread vaccination for the control of cholera. R...

journal_title：Infection and immunity

authors： Wu JY,Wade WF,Taylor RK

更新日期：2001-12-01 00:00:00

abstract：:The mechanism of in vitro synergistic lysis of sheep erythrocytes by Corynebacterium ovis and Corynebacterium equi was investigated. Hemolysis required (i) the action of phospholipase D from C. ovis, (ii) the action of an extracellular protein of C. equi, and (iii) Mg2+. Maximum lysis required imposition on the system...

journal_title：Infection and immunity

authors： Bernheimer AW,Linder R,Avigad LS

更新日期：1980-07-01 00:00:00

abstract：:The cell surface hydrophobicity of 10 pigmented and 4 nonpigmented clinical Serratia marcescens strains was studied, based on the ability of the strains to adhere to hydrocarbons and to polystyrene. The cell surface hydrophobicity depended greatly on growth temperature; all of the strains tested were adherent followin...

journal_title：Infection and immunity

authors： Rosenberg M,Blumberger Y,Judes H,Bar-Ness R,Rubinstein E,Mazor Y

更新日期：1986-03-01 00:00:00

abstract：:Polyamines such as putrescine, spermidine, and cadaverine are small, polycationic molecules that are required for optimal growth in all cells. The intracellular concentrations of these molecules are maintained by de novo synthesis and transport pathways. The human pathogen Streptococcus pneumoniae possesses a putative...

journal_title：Infection and immunity

authors： Ware D,Jiang Y,Lin W,Swiatlo E

更新日期：2006-01-01 00:00:00