Circulating promyelocytes and low levels of CD16 expression on polymorphonuclear leukocytes accompany early-onset periodontitis.

abstract：:Murine bone marrow-derived dendritic cells (DC) can phagocytose and process Salmonella enterica serovar Typhimurium for peptide presentation on major histocompatibility complex class I (MHC-I) and MHC-II molecules. To investigate if a serovar Typhimurium encounter with DC induces maturation and downregulates their abi...

journal_title：Infection and immunity

authors： Svensson M,Johansson C,Wick MJ

更新日期：2000-11-01 00:00:00

abstract：:A group of insertion mutants was used to define the genes of plasmid pDC5 required for the expression of mannose-resistant fimbriae. Minicell experiments identified four polypeptides (71,000, 45,000, 27,000, and 17,000 daltons) concerned with fimbrial production, the smallest of these being the fimbrial subunit. The a...

journal_title：Infection and immunity

authors： Clegg S,Pierce JK

更新日期：1983-12-01 00:00:00

abstract：:An immunological assay utilizing double-diffusion principles was developed for identification of Pseudomonas aeruginosa mutants deficient in toxin A. Mutations were chemically induced, and mutants were isolated from P. aeruginosa strain PA103. Quantitative assays, both enzymatic and immunological, indicated that five ...

journal_title：Infection and immunity

authors： Ohman DE,Sadoff JC,Iglewski BH

更新日期：1980-06-01 00:00:00

abstract：:This study has demonstrated the extreme sensitivity of Chlamydia trachomatis growing in McCoy cells to small changes in external amino acid supply. In the absence of cycloheximide, a decrease in the amino acid concentration of medium to 75% of control values was sufficient to induce the growth of enlarged chlamydial f...

journal_title：Infection and immunity

authors： Harper A,Pogson CI,Jones ML,Pearce JH

更新日期：2000-03-01 00:00:00

abstract：:Among a number of laboratory strains of Listeria monocytogenes used in experimental infection, strain LO28 is highly capable of inducing robust beta interferon (IFN-β) production in infected macrophages. In this study, we investigated the molecular mechanism of the IFN-β-inducing ability of LO28 by comparing it with t...

journal_title：Infection and immunity

authors： Yamamoto T,Hara H,Tsuchiya K,Sakai S,Fang R,Matsuura M,Nomura T,Sato F,Mitsuyama M,Kawamura I

更新日期：2012-07-01 00:00:00

abstract：:The diarrheagenic pathogen enteropathogenic Escherichia coli (EPEC) is responsible for significant infant mortality and morbidity, particularly in developing countries. EPEC pathogenesis relies on a type III secretion system-mediated transfer of virulence effectors into host cells. EPEC modulates host cell survival an...

journal_title：Infection and immunity

authors： Roxas JL,Koutsouris A,Viswanathan VK

更新日期：2007-05-01 00:00:00

abstract：:Changes in the structural components of the Streptococcus pyogenes membrane between exponential and early stationary phases of growth are reported. The overall protein composition ranged from 70 to 73% of the dry weight of the membranes, irrespective of the phase of growth from which they were isolated. Amino acid ana...

journal_title：Infection and immunity

authors： van de Rijn I,Kessler RE

更新日期：1979-12-01 00:00:00

abstract：:Vibrio cholerae accessory colonization factor genes (acfA, B, C, and D) are required for efficient intestinal colonization. Expression of acf genes is under the control of a regulatory cascade that also directs the synthesis of cholera toxin and proteins involved in the biogenesis of the toxin-coregulated pilus. The g...

journal_title：Infection and immunity

authors： Everiss KD,Hughes KJ,Kovach ME,Peterson KM

更新日期：1994-08-01 00:00:00

abstract：:Relapsing fever (RF) is a spirochetal infection characterized by relapses of a febrile illness and spirochetemia due to the sequential appearance and disappearance of isogenic serotypes in the blood. The only difference between isogenic serotypes is the variable major outer membrane lipoprotein. In the absence of spec...

journal_title：Infection and immunity

authors： Sethi N,Sondey M,Bai Y,Kim KS,Cadavid D

更新日期：2006-11-01 00:00:00

abstract：:Mycoplasma pneumoniae is a leading, worldwide cause of death and disability due to pneumonia. Mycoplasma pulmonis infection in mice is an invaluable model for the study of host defenses against respiratory mycoplasmas in vivo. C3H/HeN mice are much more susceptible to acute inflammatory lung disease due to M. pulmonis...

journal_title：Infection and immunity

authors： Cartner SC,Simecka JW,Lindsey JR,Cassell GH,Davis JK

更新日期：1995-10-01 00:00:00

abstract：:Mutation of retS (rtsM) of Pseudomonas aeruginosa strain PA103 reduces its virulence in both ocular and respiratory murine models of infection. In vitro, retS mutants exhibit loss of the ExsA-regulated type III secretion system (TTSS), reduced twitching motility, and a decrease in association with, invasion of, and su...

journal_title：Infection and immunity

authors： Zolfaghar I,Evans DJ,Ronaghi R,Fleiszig SM

更新日期：2006-07-01 00:00:00

abstract：:Neutrophils are the first cells to infiltrate to the site of Leishmania promastigote infection, and these cells help to reduce parasite burden shortly after infection is initiated. Several clinical reports indicate that neutrophil recruitment is sustained over the course of leishmaniasis, and amastigote-laden neutroph...

journal_title：Infection and immunity

authors： Carlsen ED,Hay C,Henard CA,Popov V,Garg NJ,Soong L

更新日期：2013-11-01 00:00:00

abstract：:Nonopsonic invasion of mononuclear phagocytes by Mycobacterium tuberculosis is likely important in the establishment of a primary infection in the lung. M. tuberculosis binds to a variety of phagocyte receptors, of which the mannose receptor and complement receptor type 3 (CR3) may support nonopsonic binding. CR3, a b...

journal_title：Infection and immunity

authors： Cywes C,Godenir NL,Hoppe HC,Scholle RR,Steyn LM,Kirsch RE,Ehlers MR

更新日期：1996-12-01 00:00:00

abstract：:Species-specific antibody epitopes within several major immunoreactive protein orthologs of Ehrlichia species have recently been identified and molecularly characterized. In this study, dominant B-cell epitopes within the acidic (pI 5.35) ankyrin repeat-containing 200-kDa major immunoreactive protein (gp200) of Ehrlic...

journal_title：Infection and immunity

authors： Nethery KA,Doyle CK,Zhang X,McBride JW

更新日期：2007-10-01 00:00:00

abstract：:Two distinct and complementary pathways, one mediated by perforin and the other dependent upon CD95 (Fas), effect cell-mediated cytotoxicity. We examined the relative roles of these pathways in host defenses against the intracellular bacterial pathogen Listeria monocytogenes by using murine listeriosis as a model syst...

journal_title：Infection and immunity

authors： Jensen ER,Glass AA,Clark WR,Wing EJ,Miller JF,Gregory SH

更新日期：1998-09-01 00:00:00

abstract：:Infection of inbred mouse strains with Borrelia burgdorferi results in the development of experimental Lyme arthritis. The degree of arthritic pathology has been suggested to correlate with the level of spirochete burden within tissues. To investigate this further, we infected resistant DBA/2 (DBA) and susceptible C3H...

journal_title：Infection and immunity

authors： Brown CR,Reiner SL

更新日期：1998-05-01 00:00:00

abstract：:Most patients with juvenile periodontitis manifest serum antibodies, sometimes at very high titers, to antigens of Actinobacillus actinomycetemcomitans, but the antigens inducing the immune response have been only partly characterized. We separated A. actinomycetemcomitans serotype b cells into protein, lipopolysaccha...

journal_title：Infection and immunity

authors： Page RC,Sims TJ,Engel LD,Moncla BJ,Bainbridge B,Stray J,Darveau RP

更新日期：1991-10-01 00:00:00

abstract：:We describe here a Sprague-Dawley rat model for chronic osteomyelitis. Staphylococcus aureus and sodium morrhuate were implanted by either microdrilling or direct needle injection into the tibiae of rats. Of 107 rats, 87 (81%) developed osteomyelitis when a high-speed drill was used for implantation, and 27 (51%) of 5...

journal_title：Infection and immunity

authors： Rissing JP,Buxton TB,Weinstein RS,Shockley RK

更新日期：1985-03-01 00:00:00

abstract：:Comparisons of the course of coccidioidomycosis in two strains of inbred mice established that BALB/c mice are significantly more susceptible to pulmonary infection with Coccidioides immitis than are DBA/2 mice. The susceptibility of BALB/c mice does not reside in their inability to mount a delayed-type hypersensitivi...

journal_title：Infection and immunity

authors： Cox RA,Kennell W,Boncyk L,Murphy JW

更新日期：1988-01-01 00:00:00

abstract：:Streptococcus pneumoniae is a major cause of illness and death in children in developing countries. In these children, zinc deficiency is associated with an increased risk of acute respiratory tract infections, which can be reduced by daily zinc administration. Severe infections decrease zinc levels in plasma and may ...

journal_title：Infection and immunity

authors： Strand TA,Hollingshead SK,Julshamn K,Briles DE,Blomberg B,Sommerfelt H

更新日期：2003-04-01 00:00:00

abstract：:Klebsiella pneumoniae is a leading cause of both community-acquired and nosocomial gram-negative-bacterial pneumonia. A further clinical complication of pulmonary K. pneumoniae infection is dissemination of bacteria from the lung into the peripheral blood, resulting in bacteremia concurrent with the localized pulmonar...

journal_title：Infection and immunity

authors： Moore TA,Perry ML,Getsoian AG,Newstead MW,Standiford TJ

更新日期：2002-11-01 00:00:00

abstract：:Escherichia coli O157:H7 is an important pathogen of humans. Cattle are most frequently identified as the primary source of infection, and therefore, reduction in E. coli O157:H7 prevalence in cattle by vaccination represents an attractive strategy for reducing the incidence of human disease. H7 flagella have been imp...

journal_title：Infection and immunity

authors： McNeilly TN,Naylor SW,Mahajan A,Mitchell MC,McAteer S,Deane D,Smith DG,Low JC,Gally DL,Huntley JF

更新日期：2008-06-01 00:00:00

abstract：:A chemically defined medium developed for Neisseria gonorrhoeae was modified to support the growth of Campylobacter jejuni and Campylobacter coli. A total of 76 isolates of C. jejuni and 14 isolates of C. coli were tested on this medium, which was designated Campylobacter defined medium (CDM), over a 3-month period. A...

journal_title：Infection and immunity

authors： Tenover FC,Knapp JS,Patton C,Plorde JJ

更新日期：1985-05-01 00:00:00

abstract：:Monoclonal antibody MASC1-MR9 of isotype immunoglobulin M was generated in LOU/C rats by immunization with heat-killed Salmonella thompson (serogroup C1, O-antigen 6,7 lipopolysaccharide) bacteria which had been further enriched for O-antigen by coating with homologous lipopolysaccharide. Eight monoclonal antibodies w...

journal_title：Infection and immunity

authors： Nnalue NA,Weintraub A,Lindberg AA

更新日期：1991-01-01 00:00:00

abstract：:The intracellular pathogen Listeria monocytogenes replicates mainly in resting macrophages and hepatocytes residing in infected tissues. Both innate and acquired resistance strongly depend on activation of listericidal capacities of macrophages by gamma interferon (IFN-gamma) produced by natural killer cells and T lym...

journal_title：Infection and immunity

authors： Szalay G,Hess J,Kaufmann SH

更新日期：1995-08-01 00:00:00

abstract：:Protamines (salmine prepared from sperm DNA of salmon and clupeine from herring sperm), which are basic peptides rich in arginine, were found to inhibit the proteolytic activity of arginine-specific cysteine protease (RC-protease) from Porphyromonas gingivalis. Lineweaver-Burk plot analysis revealed that the protamine...

journal_title：Infection and immunity

authors： Kontani M,Amano A,Nakamura T,Nakagawa I,Kawabata S,Hamada S

更新日期：1999-09-01 00:00:00

abstract：:Vibrio cholerae is the causative bacteria of the diarrheal disease cholera, but it also persists in aquatic environments, where it displays an expression profile that is distinct from that during infection. Upon entry into the host, a tightly regulated circuit coordinates the induction of two major virulence factors: ...

journal_title：Infection and immunity

authors： Hay AJ,Yang M,Xia X,Liu Z,Hammons J,Fenical W,Zhu J

更新日期：2016-12-29 00:00:00

abstract：:Four monoclonal antibodies against Escherichia coli J5 were studied. Each of these monoclonal antibodies reacted with purified lipopolysaccharides from E. coli J5, the deep rough mutant Salmonella minnesota Re595, Agrobacterium tumefaciens, and Pseudomonas aeruginosa PAO1 as well as with the purified lipid A of P. aer...

journal_title：Infection and immunity

authors： Mutharia LM,Crockford G,Bogard WC Jr,Hancock RE

更新日期：1984-09-01 00:00:00

abstract：:Performing patch-clamp experiments on human macrophages, we show that the K(+) channel MaxiK is activated by lipopolysaccharide, peptidoglycan, and interleukin-1. Cytokine production initiated by several Toll-like receptor (TLR) ligands and by interleukin-1 is inhibited by MaxiK blockade. This provides evidence for fu...

journal_title：Infection and immunity

authors： Scheel O,Papavlassopoulos M,Blunck R,Gebert A,Hartung T,Zähringer U,Seydel U,Schromm AB

更新日期：2006-07-01 00:00:00

abstract：:Yersinia pestis causes a rapid, lethal disease referred to as plague. Y. pestis actively inhibits the innate immune system to generate a noninflammatory environment during early stages of infection to promote colonization. The ability of Y. pestis to create this early noninflammatory environment is in part due to the ...

journal_title：Infection and immunity

authors： Pulsifer AR,Vashishta A,Reeves SA,Wolfe JK,Palace SG,Proulx MK,Goguen J,Bodduluri SR,Haribabu B,Uriarte SM,Lawrenz MB

更新日期：2020-02-20 00:00:00