Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

abstract：:Streptococcus pneumoniae infection leads to multifold increases in sialyltransferase, galactosyltransferase, alpha 2-fucosyltransferase, and alpha 3-fucosyltransferase activity of rat liver. Such changes may reflect an increased demand for glycosylation of acute-phase proteins synthesized and secreted by the liver dur...

journal_title：Infection and immunity

authors： Canonico PG,Little JS,Powanda MC,Bostian KA,Beisel WR

更新日期：1980-07-01 00:00:00

abstract：:The pathogenesis of Staphylococcus aureus infections is influenced by multiple virulence factors that are expressed under variable conditions, and this has complicated the design of an effective vaccine. Clinical trials that targeted the capsule or clumping factor A (ClfA) failed to protect the recipients against stap...

journal_title：Infection and immunity

authors： Tuchscherr LP,Buzzola FR,Alvarez LP,Lee JC,Sordelli DO

更新日期：2008-12-01 00:00:00

abstract：:Tick saliva has potent immunomodulatory properties. In arthropod-borne diseases, this effect is largely used by microorganisms to increase their pathogenicity and to evade host immune responses. We show that in Lyme borreliosis, tick salivary gland extract and a tick saliva protein, Salp15, inhibit in vitro keratinocy...

journal_title：Infection and immunity

authors： Marchal C,Schramm F,Kern A,Luft BJ,Yang X,Schuijt TJ,Hovius JW,Jaulhac B,Boulanger N

更新日期：2011-02-01 00:00:00

abstract：:A clinically isolated strain of polymorphonuclear leukocyte (PMN)-resistant Pseudomonas was found to produce an extracellular substance (PMN inhibitor) that inhibits the phagocytic and killing activities of PMN. The PMN inhibitor was purified from culture filtrates by precipitation with (NH4)2SO4 and chromatography on...

journal_title：Infection and immunity

authors： Nonoyama S,Kojo H,Mine Y,Nishida M,Goto S,Kuwahara S

更新日期：1979-05-01 00:00:00

abstract：:Increased incidence of bovine tuberculosis (TB) in the United Kingdom caused by infection with Mycobacterium bovis is a cause of considerable economic loss to farmers and the government. The Eurasian badger (Meles meles) represents a wildlife source of recurrent M. bovis infections of cattle in the United Kingdom, and...

journal_title：Infection and immunity

authors： Clark S,Cross ML,Nadian A,Vipond J,Court P,Williams A,Hewinson RG,Aldwell FE,Chambers MA

更新日期：2008-08-01 00:00:00

abstract：:Numerous studies have reported that asialo-GM(1), gangliotetraosylceramide, or moieties serve as epithelial cell receptors for Pseudomonas aeruginosa. Usually this interaction is confirmed with antibodies to asialo-GM(1). However, few, if any, of these reports have evaluated the binding of fresh clinical isolates of P...

journal_title：Infection and immunity

authors： Schroeder TH,Zaidi T,Pier GB

更新日期：2001-02-01 00:00:00

abstract：:Lactoperoxidase catalyzes the oxidation of thiocyanate by hydrogen peroxide into hypothiocyanite, a reaction which can protect bacterial and mammalian cells from killing by hydrogen peroxide. The present study demonstrates, however, that lactoperoxidase in the presence of thiocyanate can actually potentiate the bacter...

journal_title：Infection and immunity

authors： Carlsson J,Edlund MB,Hänström L

更新日期：1984-06-01 00:00:00

abstract：:Experiments were conducted in which rhesus monkeys were infected with mumps virus by inoculation into the parotid gland. Virus was isolated from buccal swab specimens from animals up to 6 days after inoculation. Immunofluorescence staining for mumps antigen was positive, and infectious virus was recovered from tissue ...

journal_title：Infection and immunity

authors： Flanagan TD,Andrada JA,Barron AL,Witebsky E

更新日期：1971-05-01 00:00:00

abstract：:Borrelia burgdorferi, a causative agent of Lyme borreliosis, is a zoonotic pathogen that survives in nutrient-limited environments within a tick, prior to transmission to its mammalian host. Survival under these prolonged nutrient-limited conditions is thought to be similar to survival during stationary phase, which i...

journal_title：Infection and immunity

authors： Fazzino L,Tilly K,Dulebohn DP,Rosa PA

更新日期：2015-12-01 00:00:00

abstract：:A protein antigen called TR-o was isolated from supernatant of a sonically treated Reiter treponeme. The isolation procedure included anion-exchange chromatography on Whatman DE-52, hydrophobic interaction chromatography on decyl agarose, and finally gel filtration on Ac-A-22 Ultrogel. The fractionations were monitore...

journal_title：Infection and immunity

authors： Petersen CS,Pedersen NS,Axelsen NH

更新日期：1982-03-01 00:00:00

abstract：:A major virulence factor of group A streptococci is M protein, a surface-exposed fibrillar molecule of which there exist more than 80 distinct serological types. Antigenic variability resides largely in the amino-terminal region of M protein, whereas the carboxy-terminal half of the molecule is highly conserved among ...

journal_title：Infection and immunity

authors： Bessen D,Fischetti VA

更新日期：1988-10-01 00:00:00

abstract：:A method for stimulating sensitized lymphocytes by inactivated herpes simplex virus was established by using cultures of washed whole blood cells. The development of the immune response of herpes simplex virus-infected guinea pigs was examined at different times in the 4-month period after infection. Humoral and cellu...

journal_title：Infection and immunity

authors： Scriba M

更新日期：1974-09-01 00:00:00

abstract：:Pulmonary washings from rabbits were freed of cells and added to the monolayers of homologous alveolar macrophages (AM). At 1 h after incubation with the pulmonary washings, many more cells adhered to glass, spread out, and showed enhanced Nitro Blue Tetrazolium reduction. The maximal effect of the pulmonary washings ...

journal_title：Infection and immunity

authors： Ando M,Suga M,Shima K,Sugimoto M,Tokuomi H

更新日期：1978-05-01 00:00:00

abstract：:Previous studies have demonstrated that both Ixodes scapularis saliva and Borrelia burgdorferi antigens modulated lymphokines and monokines in vitro. The studies presented here were designed to delineate the role of I. scapularis and B. burgdorferi in modulation of the host immune response in vivo. Infestation of C3H/...

journal_title：Infection and immunity

authors： Zeidner N,Mbow ML,Dolan M,Massung R,Baca E,Piesman J

更新日期：1997-08-01 00:00:00

abstract：:Pneumolysin (PLY), an important virulence factor of Streptococcus pneumoniae, is known to exert various effects on the host immune cells, including cytokine induction, in addition to its known cytolytic activity as a member of the thiol-activated cytolysins. It is of interest to determine whether cytolytic activity is...

journal_title：Infection and immunity

authors： Baba H,Kawamura I,Kohda C,Nomura T,Ito Y,Kimoto T,Watanabe I,Ichiyama S,Mitsuyama M

更新日期：2002-01-01 00:00:00

abstract：:The two enteropathogens Yersinia pseudotuberculosis and Yersinia enterocolitica penetrate eukaryotic cells in vitro through invasin, a surface-exposed protein. In contrast, Yersinia pestis, the causative agent of plague, is unable to enter mammalian cell lines, although the inv gene is present on its chromosome. Altho...

journal_title：Infection and immunity

authors： Simonet M,Riot B,Fortineau N,Berche P

更新日期：1996-01-01 00:00:00

abstract：:Interaction of bacteria with mucosal surfaces can modulate the production of proinflammatory cytokines and adhesion molecules produced by epithelial cells. Previously, we showed that expression of interleukin-8 (IL-8) and intercellular adhesion molecule 1 (ICAM-1) by gingival epithelial cells increases following inter...

journal_title：Infection and immunity

authors： Huang GT,Kim D,Lee JK,Kuramitsu HK,Haake SK

更新日期：2001-03-01 00:00:00

abstract：:Phagocytosis and mechanisms of killing of Aspergillus fumigatus conidia by murine alveolar macrophages (AM), which are the main phagocytic cells of the innate immunity of the lung, were investigated. Engulfment of conidia by murine AM lasts 2 h. Killing of A. fumigatus conidia by AM begins after 6 h of phagocytosis. S...

journal_title：Infection and immunity

authors： Philippe B,Ibrahim-Granet O,Prévost MC,Gougerot-Pocidalo MA,Sanchez Perez M,Van der Meeren A,Latgé JP

更新日期：2003-06-01 00:00:00

abstract：:We have characterized the natural immune responses to the 19-kDa domain of merozoite surface protein 1 in individuals from an area of western Kenya in which malaria is holoendemic. We used the three known natural variant forms of the yeast-expressed recombinant 19-kDa fragment that are referred to as the E-KNG, Q-KNG,...

journal_title：Infection and immunity

authors： Shi YP,Sayed U,Qari SH,Roberts JM,Udhayakumar V,Oloo AJ,Hawley WA,Kaslow DC,Nahlen BL,Lal AA

更新日期：1996-07-01 00:00:00

abstract：:Polymicrobial intra-abdominal infections (IAIs) are a significant cause of morbidity and mortality, particularly when fungal pathogens are involved. Our experimental murine model of IAI involving intraperitoneal inoculation of Candida albicans and Staphylococcus aureus results in synergistic lethality (∼80%) due to ex...

journal_title：Infection and immunity

authors： Ikeh MAC,Fidel PL Jr,Noverr MC

更新日期：2018-06-21 00:00:00

abstract：:Two fragments with molecular weights of 111,000 (fragment I) and 59,000 (fragment II) were separated from each other by gel filtration of dithiothreitol and urea-treated, trypsinized derivative toxin (molecular weight, 170,000) of the proteolytic Okra strain of Clostridium botulinum type B on a column of Sephadex G-20...

journal_title：Infection and immunity

authors： Kozaki S,Miyazaki S,Sakaguchi G

更新日期：1977-12-01 00:00:00

abstract：:Protective immunity in mice to the infective third-stage larvae (L3) of Strongyloides stercoralis was shown to be dependent on immunoglobulin M (IgM), complement activation, and granulocytes. The objectives of the present study were to determine whether IgG was also a protective antibody isotype and to define the spec...

journal_title：Infection and immunity

authors： Ligas JA,Kerepesi LA,Galioto AM,Lustigman S,Nolan TJ,Schad GA,Abraham D

更新日期：2003-12-01 00:00:00

abstract：:Monoclonal antibodies were raised against a bactericidal protein fraction that was purified from an extract of bovine neutrophil granules and that was previously shown (A. Savoini, R. Marzari, L. Dolzani, D. Serranò, G. Graziosi, R. Gennaro, and D. Romeo, Antimicrob. Agents Chemother. 26:405-407, 1984) to inhibit bact...

journal_title：Infection and immunity

authors： Marzari R,Scaggiante B,Skerlavaj B,Bittolo M,Gennaro R,Romeo D

更新日期：1988-08-01 00:00:00

abstract：:Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that other mechanisms of vir...

journal_title：Infection and immunity

authors： McClelland EE,Perrine WT,Potts WK,Casadevall A

更新日期：2005-10-01 00:00:00

abstract：:Peptidoglycans of organisms belonging to the strictly anaerobic family Bacteroidaceae were investigated for the presence of lanthionine. Different procedures for the quantitation of lanthionine were compared. Performic acid and peroxide oxidation procedures on 35S-labeled peptidoglycan from Fusobacterium nucleatum Fev...

journal_title：Infection and immunity

authors： Vasstrand EN,Jensen HB,Miron T,Hofstad T

更新日期：1982-04-01 00:00:00

abstract：:We evaluated sexual recombination in the apicomplexan parasite Theileria parva using genome-wide marker analysis of haploid sporozoite populations obtained from infected Rhipicephalus appendiculatus ticks. Analysis of 231 parasite clones derived by in vitro infection of bovine lymphocytes revealed 48 distinct combinat...

journal_title：Infection and immunity

authors： Katzer F,Ngugi D,Oura C,Bishop RP,Taracha EL,Walker AR,McKeever DJ

更新日期：2006-10-01 00:00:00

abstract：:Attachment of Mycobacterium avium subsp. paratuberculosis to host tissue and penetration of mucosal surfaces are pivotal events in the pathogenesis of Johne's disease. Fibronectin (FN) binding is required for attachment and internalization of several mycobacteria by epithelial cells in vitro. The objective of this stu...

journal_title：Infection and immunity

authors： Secott TE,Lin TL,Wu CC

更新日期：2001-04-01 00:00:00

abstract：:The Lyme disease spirochete, Borrelia burgdorferi, is introduced into human hosts via tick bites. Among the cell types present in the skin which may initially contact spirochetes are mast cells. Since spirochetes are known to activate a variety of cell types in vitro, we tested whether B. burgdorferi spirochetes could...

journal_title：Infection and immunity

authors： Talkington J,Nickell SP

更新日期：1999-03-01 00:00:00

abstract：:Heterogeneic autoantibodies against axonal neurofilament proteins of mature mouse neurons grown in vitro were detected by the indirect immunofluorescence technique in 12.7% (9 of 71) of the sera from nonhuman primates infected with kuru, in 14.5% (17 of 117) and 4% (1 of 25), respectively, of the sera from nonhuman pr...

journal_title：Infection and immunity

authors： Aoki T,Gibbs CJ Jr,Sotelo J,Gajdusek DC

更新日期：1982-10-01 00:00:00

abstract：:The combining sites of type 1 fimbrial lectins of various species of enterobacteria were studied by measuring the inhibitory activity of linear and branched oligosaccharides and several glycosides of D-mannose on the agglutination of yeast cells by the organisms. The results showed that all five strains of Escherichia...

journal_title：Infection and immunity

authors： Firon N,Ofek I,Sharon N

更新日期：1984-03-01 00:00:00