Inhibitory effect of Pseudomonas aeruginosa on the phagacytic and killing activities of rabbit polymorphonuclear leukocytes: purification and characterization of an inhibitor of polymorphonuclear leukocyte function.

abstract：:The interaction of purified human fibrinogen with Aspergillus fumigatus conidia was investigated by immunofluorescence and electron microscopy and binding assays with radiolabeled proteins. We described the localization of the binding sites on the A. fumigatus conidia and on the fibrinogen molecule and determined the ...

journal_title：Infection and immunity

authors： Annaix V,Bouchara JP,Larcher G,Chabasse D,Tronchin G

更新日期：1992-05-01 00:00:00

abstract：:Lipid X, a precursor in the biosynthesis of lipid A, has been claimed to possess most of the immunostimulatory activity but none of the toxicity of endotoxin. However, recent work shows that synthetic lipid X can be contaminated with small amounts of N,O-acylated disaccharide-1-phosphate (H. Aschauer, A. Grob, J. Hild...

journal_title：Infection and immunity

authors： Lam C,Hildebrandt J,Schütze E,Rosenwirth B,Proctor RA,Liehl E,Stütz P

更新日期：1991-07-01 00:00:00

abstract：:Mannan (MAN) extracted from Candida albicans 20A was investigated for its potential as an antigen in the detection of cell-mediated immunity (CMI) in vivo and in vitro and for its ability to modulate CMI when administered intravenously (i.v.). CBA/J mice were either immunized as adults by the cutaneous inoculation of ...

journal_title：Infection and immunity

authors： Domer JE,Garner RE,Befidi-Mengue RN

更新日期：1989-03-01 00:00:00

abstract：:The triggering receptor expressed on myeloid cell type 1 (TREM-1) is a cell surface molecule that has been identified on both human and murine polymorphonuclear neutrophils and mature monocytes. The activation of TREM-1 in the presence of microbial components amplifies the inflammatory response and may be responsible ...

journal_title：Infection and immunity

authors： Gibot S,Buonsanti C,Massin F,Romano M,Kolopp-Sarda MN,Benigni F,Faure GC,Béné MC,Panina-Bordignon P,Passini N,Lévy B

更新日期：2006-05-01 00:00:00

abstract：:Heart and muscle tissues appear to be specific target organs for the in vivo inhibition of protein synthesis by diphtheria toxin. ...

journal_title：Infection and immunity

authors： Bowman CG,Imhoff JG,Bonventre PF

更新日期：1970-11-01 00:00:00

abstract：:Humans infected with the dimorphic fungus Blastomyces dermatitidis develop strong T-lymphocyte responses to WI-1, an immunodominant antigen that has been shown to elicit protective immunity in mice. In the present study, the T-cell epitopes of WI-1 and human leukocyte antigen (HLA) restricting elements that display th...

journal_title：Infection and immunity

authors： Chang WL,Audet RG,Aizenstein BD,Hogan LH,DeMars RI,Klein BS

更新日期：2000-02-01 00:00:00

abstract：:We previously identified a cell wall-associated protein from Fusobacterium nucleatum, a Gram-negative bacterium of the oral cavity, that induces human beta defensin 2 (hBD-2) in primary human oral epithelial cells (HOECs) and designated it FAD-I (Fusobacterium-associated defensin inducer). Here, we report differential...

journal_title：Infection and immunity

authors： Bhattacharyya S,Ghosh SK,Shokeen B,Eapan B,Lux R,Kiselar J,Nithianantham S,Young A,Pandiyan P,McCormick TS,Weinberg A

更新日期：2016-04-22 00:00:00

abstract：:To study responses to Mycobacterium leprae antigens, we developed an in vitro model system in which latex particles coated with M. leprae sonic extract (MLSON) antigen were presented to monocytes. Uptake and oxidative response as measured by superoxide production to these antigens were investigated. Phagocytosis of ML...

journal_title：Infection and immunity

authors： Hasan RS,Dockrell HM,Jamil S,Chiang TJ,Hussain R

更新日期：1993-09-01 00:00:00

abstract：:Macrophage recognition of Salmonella enterica serovar Typhimurium leads to a cascade of signaling events, including the activation of Src family and Syk kinases and the production of reactive oxygen species (ROS), which are critical for host innate defense during early stages of bacterial infection. ROS production dep...

journal_title：Infection and immunity

authors： Charles JF,Humphrey MB,Zhao X,Quarles E,Nakamura MC,Aderem A,Seaman WE,Smith KD

更新日期：2008-06-01 00:00:00

abstract：:An immunosuppressed rat model of Pneumocystis carinii pneumonia is described that utilizes simple, noninvasive intratracheal (i.t.) inoculation of cryopreserved parasites and results in development of severe P. carinii pneumonia within 5 weeks. This is an improvement over the most commonly used models of P. carinii pn...

journal_title：Infection and immunity

authors： Boylan CJ,Current WL

更新日期：1992-04-01 00:00:00

abstract：:To determine whether an ongoing response to Leishmania major would affect the response to a non-cross-reacting, non-leishmanial antigen, susceptible BALB/c mice and resistant C3H mice were infected with L. major parasites expressing Escherichia coli beta-galactosidase (beta-GAL); this parasite was designated L. major-...

journal_title：Infection and immunity

authors： Chakkalath HR,Siddiqui AA,Shankar AH,Dobson DE,Beverley SM,Titus RG

更新日期：2000-02-01 00:00:00

abstract：:The genetic determinants of the 120-kDa cytotoxin of Actinobacillus pleuropneumoniae serotype 2 were isolated from a lambda DNA library by a plaque immunoblot technique. Expression of the 120-kDa polypeptide was confirmed by Western immunoblot analysis of infected Escherichia coli cell lysates, which were shown to be ...

journal_title：Infection and immunity

authors： MacDonald J,Rycroft AN

更新日期：1992-07-01 00:00:00

abstract：:Beta-1,2-linked mannosides (beta-Mans) are believed to contribute to Candida albicans virulence. The presence of beta-Mans has been chemically established for two molecules (phosphopeptidomannan [PPM] and phospholipomannan) that are noncovalently linked to the cell wall, where they correspond to specific epitopes. How...

journal_title：Infection and immunity

authors： Fradin C,Slomianny MC,Mille C,Masset A,Robert R,Sendid B,Ernst JF,Michalski JC,Poulain D

更新日期：2008-10-01 00:00:00

abstract：:Helicobacter mustelae, like Helicobacter pylori, possesses two flagellin proteins, FlaA and FlaB. Isogenic mutant strains of H. mustelae have been constructed by disruption of the flaA or flaB gene with a kanamycin resistance cassette or by introduction of both a kanamycin and a chloramphenicol resistance gene to prod...

journal_title：Infection and immunity

authors： Andrutis KA,Fox JG,Schauer DB,Marini RP,Li X,Yan L,Josenhans C,Suerbaum S

更新日期：1997-05-01 00:00:00

abstract：:The mechanisms of immunity to salmonellae conferred by immunization with live vaccines were studied by adoptive transfer using the mouse-virulent strain Salmonella typhimurium C5 and innately susceptible BALB/c (ltys) mice. This organism cannot establish a sublethal infection in naive BALB/c mice. Animals immunized 2 ...

journal_title：Infection and immunity

authors： Mastroeni P,Villarreal-Ramos B,Hormaeche CE

更新日期：1993-09-01 00:00:00

abstract：:The complete nucleotide sequence of a 612-base-pair DNA fragment containing the gene for the major fimbrial subunit of CS3 of enterotoxigenic Escherichia coli is presented. A possible promoter region, a ribosome-binding site, and two potential signal peptidase cleavage sites are indicated. Unlike the best-studied fimb...

journal_title：Infection and immunity

authors： Boylan M,Smyth CJ,Scott JR

更新日期：1988-12-01 00:00:00

abstract：:Infection of inbred mouse strains with Borrelia burgdorferi results in the development of experimental Lyme arthritis. The degree of arthritic pathology has been suggested to correlate with the level of spirochete burden within tissues. To investigate this further, we infected resistant DBA/2 (DBA) and susceptible C3H...

journal_title：Infection and immunity

authors： Brown CR,Reiner SL

更新日期：1998-05-01 00:00:00

abstract：:Studies were carried out to determine whether treatment of mice with the synthetic adjuvant muramyl dipeptide afforded any resistance to infection with the obligate intracellular protozoan Toxoplasma gondii. Marked resistance to lethal challenge infection was observed in CBA but not C57BL/6 mice pretreated with muramy...

journal_title：Infection and immunity

authors： Krahenbuhl JL,Sharma SD,Ferraresi RW,Remington JS

更新日期：1981-02-01 00:00:00

abstract：:Analysis of the specificity of bactericidal antibodies in normal, convalescent, and postvaccination human sera is important in understanding human immunity to meningococcal infections and can aid in the design of an effective group B vaccine. A collection of human sera, including group C and group B convalescent-phase...

journal_title：Infection and immunity

authors： Schmiel DH,Moran EE,Keiser PB,Brandt BL,Zollinger WD

更新日期：2011-10-01 00:00:00

abstract：:The human gastric pathogen Helicobacter pylori modifies host cholesterol via glycosylation and incorporates the glycosylated cholesterol into its membrane; however, the benefits of cholesterol to H. pylori are largely unknown. We speculated that cholesterol in the H. pylori membrane might alter the susceptibility of t...

journal_title：Infection and immunity

authors： Trainor EA,Horton KE,Savage PB,Testerman TL,McGee DJ

更新日期：2011-01-01 00:00:00

abstract：:The mouse humoral immune response toward native or detergent-extracted outer membrane vesicles (NOMVs and DOMVs, respectively) from Neisseria meningitidis was determined after intranasal immunization. Both preparations elicited high frequencies of NOMV-specific antibody-forming cells (AFCs) locally in the nasal associ...

journal_title：Infection and immunity

authors： Guthrie T,Wong SY,Liang B,Hyland L,Hou S,Høiby EA,Andersen SR

更新日期：2004-05-01 00:00:00

abstract：:Our previous studies identified two iron-regulated cytoplasmic membrane proteins of 32 and 36 kDa expressed by both Staphylococcus epidermidis and Staphylococcus aureus. In this study we show by Triton X-114 phase partitioning and tritiated palmitic acid labelling that these proteins are lipoproteins which are anchore...

journal_title：Infection and immunity

authors： Cockayne A,Hill PJ,Powell NB,Bishop K,Sims C,Williams P

更新日期：1998-08-01 00:00:00

abstract：:Rabbit endogenous pyrogens were of about the same molecular size, but showed considerable heterogeneity of their isoelectric points. We attempted to show that this heterogeneity was attributable to variable glycosylation of a single polypeptide chain. When peritoneal exudate cells were stimulated to make pyrogens in t...

journal_title：Infection and immunity

authors： Murphy PA,Cebula TA,Windle BE

更新日期：1981-10-01 00:00:00

abstract：:Groups of mice were immunized either subcutaneously or intranasally with purified Brucella melitensis lipopolysaccharide (LPS) or with LPS as a noncovalent complex with Neisseria meningitidis group B outer membrane protein (LPS-GBOMP). Control mice were inoculated with sterile saline. Two doses of vaccine were given 4...

journal_title：Infection and immunity

authors： Bhattacharjee AK,Izadjoo MJ,Zollinger WD,Nikolich MP,Hoover DL

更新日期：2006-10-01 00:00:00

abstract：:Fourteen strains of Escherichia coli were tested for ability to cause infective endocarditis in rabbits prepared by prior placement of an intracardiac catheter. Strains that were resistant to the bactericidal action of serum caused E. coli endocarditis in 91.4% of rabbits, whereas serum-sensitive strains usually faile...

journal_title：Infection and immunity

authors： Durack DT,Beeson PB

更新日期：1977-04-01 00:00:00

abstract：:The ability of Streptococcus salivarius strain TOVE-R to inhibit the ecological emergence of virulent representatives of the most prevalent human mutans streptococci on the teeth of specific pathogen-free Osborne-Mendel rats was studied. Rats which were infected by TOVE-R, or either S. mutans 10449S or S. sobrinus 671...

journal_title：Infection and immunity

authors： Tanzer JM,Kurasz AB,Clive J

更新日期：1985-07-01 00:00:00

abstract：:We reexamined the binding specificity of the Shiga-like toxin variant associated with porcine edema disease, SLT2e, which is reported to be more cytotoxic for Vero cells than for HeLa cells, by using receptor-deficient cells and a liposomal insertion system for purified glycolipids. We found that SLT2e preferentially ...

journal_title：Infection and immunity

authors： Keusch GT,Jacewicz M,Acheson DW,Donohue-Rolfe A,Kane AV,McCluer RH

更新日期：1995-03-01 00:00:00

abstract：:Vibrio cholerae O1 has two biotypes, El Tor and Classical, and the latter is now presumed to be extinct in nature. Under carbohydrate-rich growth conditions, El Tor biotype strains produce the neutral fermentation end product 2,3-butanediol (2,3-BD), which prevents accumulation of organic acids from mixed acid ferment...

journal_title：Infection and immunity

authors： Bari W,Song YJ,Yoon SS

更新日期：2011-08-01 00:00:00

abstract：:Mucin glycoproteins are secreted in large amounts by the intestinal epithelium and constitute an efficient component of innate immune defenses to promote homeostasis and protect against enteric pathogens. In this study, our objective was to investigate how the bacterial enteropathogen Shigella flexneri, which causes b...

journal_title：Infection and immunity

authors： Sperandio B,Fischer N,Joncquel Chevalier-Curt M,Rossez Y,Roux P,Robbe Masselot C,Sansonetti PJ

更新日期：2013-10-01 00:00:00

abstract：:Isolates of Thermoplasma acidophilum were divided into serological groups based on immunodiffusion studies of solubilized-membrane preparations. ...

journal_title：Infection and immunity

authors： Bohlool BB,Brock TD

更新日期：1974-07-01 00:00:00