Immunodiffusion analysis of membranes of Thermoplasma acidophilum.

abstract：:Cyclic dimeric GMP (c-di-GMP), a bacterial second messenger, is known to regulate bacterial biofilm and sessility. Replication of an obligatory intracellular pathogen, Ehrlichia chaffeensis, is characterized by formation of bacterial aggregates called morulae inside membrane-bound inclusions. When E. chaffeensis matur...

journal_title：Infection and immunity

authors： Kumagai Y,Matsuo J,Cheng Z,Hayakawa Y,Rikihisa Y

更新日期：2011-10-01 00:00:00

abstract：:Oxygenated fatty acids, or oxylipins, play an essential role in physiological signaling and developmental processes in animals, plants, and fungi. Previous characterization of three Aspergillus fumigatus dioxygenases (PpoA, PpoB, and PpoC), similar in sequence to mammalian cyclooxygenases, showed that PpoA is responsi...

journal_title：Infection and immunity

authors： Dagenais TR,Chung D,Giles SS,Hull CM,Andes D,Keller NP

更新日期：2008-07-01 00:00:00

abstract：:A dextranase preparation (AD17) partially purified from a culture liquor of Spicaria violacea strain IFO 6120 significantly inhibited the formation of artifcial dental plaque on a steel wire or on an extracted tooth surface. Changes in the surface morphology of Streptococcus mutans cells due to AD17 action were studie...

journal_title：Infection and immunity

authors： Hamada S,Mizuno J,Murayama Y,Ooshima Y,Masuda N

更新日期：1975-12-01 00:00:00

abstract：:Guinea pig peritoneal or alveolar macrophages were inoculated with Mycoplasma pneumoniae cells. Extracellular mycoplasms were killed by complement treatment, and the effect of macrophage action on the number of the remaining viable mycoplasmas was observed. The complement killing was to some extent inhibited by the pr...

journal_title：Infection and immunity

authors： Erb P,Bredt W

更新日期：1979-07-01 00:00:00

abstract：:Legionella pneumophila is the predominant cause of Legionnaires' disease in the United States and Europe, while Legionella longbeachae is the common cause of the disease in Western Australia. Although clinical manifestations by both intracellular pathogens are very similar, recent studies have shown that phagosome bio...

journal_title：Infection and immunity

authors： Asare R,Santic M,Gobin I,Doric M,Suttles J,Graham JE,Price CD,Abu Kwaik Y

更新日期：2007-04-01 00:00:00

abstract：:Arg-gingipain (Rgp) and Lys-gingipain (Kgp) are Porphyromonas gingivalis cysteine proteinases implicated as major virulence factors in pathologies of periodontitis. We purified a 660-kDa cell-associated gingipain complex existing as a homodimer of two catalytically active monomers which comprises their catalytic and a...

journal_title：Infection and immunity

authors： Takii R,Kadowaki T,Baba A,Tsukuba T,Yamamoto K

更新日期：2005-02-01 00:00:00

abstract：:The zoopathogenic fungus Histoplasma capsulatum requires iron for growth. Intracellular growth of the fungus within mouse peritoneal macrophages is inhibited by recombinant murine gamma interferon (IFN-gamma). Such treatment of mouse peritoneal macrophages induces a marked downshift in transferrin receptors. We tested...

journal_title：Infection and immunity

authors： Lane TE,Wu-Hsieh BA,Howard DH

更新日期：1991-07-01 00:00:00

abstract：:Serum was necessary for optimal phagocytosis of Aspergillus fumigatus spores by human leukocytes, and its opsonic capacity was greatly diminished by heat inactivation (56 C, 30 min). A germination assay, described in this report, was developed to study the fate of phagocytized spores. After incubation for 3 hr with no...

journal_title：Infection and immunity

authors： Lehrer RI,Jan RG

更新日期：1970-04-01 00:00:00

abstract：:Minicells are small, anucleate cells resulting from aberrant cell divisions at the polar ends of bacilli. We have isolated minicell-producing mutant strains of Shigella flexneri 2a (MC-I) and Shigella dysenteriae 1 (MC-V) after mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine. Microscopically, broth cultures of M...

journal_title：Infection and immunity

authors： Gemski P,Griffin DE

更新日期：1980-10-01 00:00:00

abstract：:A procedure was developed to purify dermonecrotic toxin (DNT) from a sonic extract of a serotype D strain of Pasteurella multocida. Sonic extract containing DNT was applied to a DEAE-Sephacel column and eluted by a linear gradient of NaCl. Upon rechromatographing, fractions with dermonecrotic activity for guinea pigs ...

journal_title：Infection and immunity

authors： Nakai T,Sawata A,Tsuji M,Samejima Y,Kume K

更新日期：1984-11-01 00:00:00

abstract：:The adipocytokine leptin links nutritional status to immune function. Leptin signaling protects from amebiasis, but the molecular mechanism is not understood. We developed an in vitro model of ameba-host cell interaction to test the hypothesis that leptin prevents ameba-induced apoptosis in host epithelial cells. We d...

journal_title：Infection and immunity

authors： Marie CS,Verkerke HP,Paul SN,Mackey AJ,Petri WA Jr

更新日期：2012-05-01 00:00:00

abstract：:Levels of the serum opsonin mannan-binding lectin (MBL) were directly correlated with the probability of developing visceral leishmaniasis. Monocytes infected with MBL-opsonized Leishmania chagasi promastigotes secreted higher levels of tumor necrosis factor alpha and interleukin-6 than cells infected with nonopsonize...

journal_title：Infection and immunity

authors： Santos IK,Costa CH,Krieger H,Feitosa MF,Zurakowski D,Fardin B,Gomes RB,Weiner DL,Harn DA,Ezekowitz RA,Epstein JE

更新日期：2001-08-01 00:00:00

abstract：:We previously reported that two surface-exposed high-molecular-weight proteins, HMW1 and HMW2, expressed by a prototypic strain of nontypeable Haemophilus influenzae (NTHI) mediate attachment to human epithelial cells. These proteins are members of a family of highly immunogenic proteins common to most nontypeable Hae...

journal_title：Infection and immunity

authors： Barenkam SJ,St Geme JW 3rd

更新日期：1996-08-01 00:00:00

abstract：:Two weeks after mice had been infected in the footpad with cells of Nocardia brasiliensis, immunoglobulin and C3 deposits were observed in tissue from the inoculation site. Both immunoglobulin and C3 were found in the actinomycotic granules that characterize the mycetoma and in the surrounding inflammatory zones, in w...

journal_title：Infection and immunity

authors： Conde C,Mancilla R,Fresan M,Ortiz-Ortiz L

更新日期：1983-06-01 00:00:00

abstract：:The mechanism by which Helicobacter pylori, which has little or no invasive activity, induces gastric-tissue inflammation and injury has not been well characterized. We have previously demonstrated that water-extracted proteins of H. pylori are capable of activating human monocytes by a lipopolysaccharide (LPS)-indepe...

journal_title：Infection and immunity

authors： Pérez-Pérez GI,Shepherd VL,Morrow JD,Blaser MJ

更新日期：1995-04-01 00:00:00

abstract：:Colony variants of Neisseria gonorrhoeae differ in their interactions with eucaryotic cells. When gonococci were cultivated with HeLa cell monolayers, the opacity phenotype (Op) became increasingly dominant in the subpopulation of organisms which adhered to the HeLa cells. Once bound, Op organisms displayed very low l...

journal_title：Infection and immunity

authors： Bessen D,Gotschlich EC

更新日期：1986-10-01 00:00:00

abstract：:Vibrio cholerae V86 El Tor Inaba caused experimental cholera in germfree ICR suckling mice. Sucklings born of gnotobiotic mothers monoassociated with the same strain were completely protected against live oral homologous challenge. ...

journal_title：Infection and immunity

authors： Shimamura T,Tazume S,Hashimoto K,Sasaki S

更新日期：1981-10-01 00:00:00

abstract：:Mycoplasma pneumoniae is a leading, worldwide cause of death and disability due to pneumonia. Mycoplasma pulmonis infection in mice is an invaluable model for the study of host defenses against respiratory mycoplasmas in vivo. C3H/HeN mice are much more susceptible to acute inflammatory lung disease due to M. pulmonis...

journal_title：Infection and immunity

authors： Cartner SC,Simecka JW,Lindsey JR,Cassell GH,Davis JK

更新日期：1995-10-01 00:00:00

abstract：:A solid-phase radioimmunoassay, applying whole Mycobacterium leprae as antigen and radiolabeled protein A from Staphylococcus aureus as antibody-detecting reagent, was used for the determination of specific immunoglobulin G (IgG) and IgM antibody responses in leprosy patients. High IgG anti-M. leprae antibody levels w...

journal_title：Infection and immunity

authors： Touw J,Langendijk EM,Stoner GL,Belehu A

更新日期：1982-06-01 00:00:00

abstract：:Enteroaggregative Escherichia coli (EAEC) is an emerging cause of diarrheal illness. Clinical data suggest that diarrhea caused by EAEC is predominantly secretory in nature, but the responsible enterotoxin has not been described. Work from our laboratories has implicated a ca. 108-kDa protein as a heat-labile enteroto...

journal_title：Infection and immunity

authors： Eslava C,Navarro-García F,Czeczulin JR,Henderson IR,Cravioto A,Nataro JP

更新日期：1998-07-01 00:00:00

abstract：:Lymphocyte blastogenesis assays and immunoblotting were used to investigate and compare murine B-cell responses to preparations of extracellular membrane blebs (BAg) and spirochetes (Ag) of Borrelia burgdorferi. Immunoblotting BAg, Ag, and medium control preparations with serum from naive and infected C57BL/10 mice re...

journal_title：Infection and immunity

authors： Whitmire WM,Garon CF

更新日期：1993-04-01 00:00:00

abstract：:Hamster trachea organ cultres were shown to consume measurable amounts of oxygen when incubated in a closed micro-chamber. Several simple and complex media were evaluated, and the optimal system involved incubating 2 to 4 mg of tracheal tissue in Tyrodes balanced salt solution at 37 C for 60 min, with oxygen activity ...

journal_title：Infection and immunity

authors： Gabridge MG

更新日期：1975-09-01 00:00:00

abstract：:The American opossum is the only experimental animal that regularly develops bacterial endocarditis spontaneously. There was no relation between the ability of opossums to clear bacteria from the bloodstream and the subsequent development of endocarditis. ...

journal_title：Infection and immunity

authors： Musher DM,Richie Y

更新日期：1974-06-01 00:00:00

abstract：:Borrelia burgdorferi resembles gram-negative bacteria in having both cellular and outer membranes. We previously showed that a lipopolysaccharide (LPS)-like material could be extracted from B. burgdorferi with phenol-chloroform-petroleum ether (PCP). The PCP extract of B. burgdorferi exhibited biological activity in s...

journal_title：Infection and immunity

authors： Katona LI,Beck G,Habicht GS

更新日期：1992-12-01 00:00:00

abstract：:Mucosal exposure to Escherichia coli elicits an inflammatory response in the urinary tract. Interleukin-6 (IL-6) is secreted into the urine, and polymorphonuclear leukocytes (PMNLs) are recruited to the site of infection. This study analyzed the ability of mucosally administered bacterial components to activate IL-6 a...

journal_title：Infection and immunity

authors： Linder H,Engberg I,Hoschützky H,Mattsby-Baltzer I,Svanborg C

更新日期：1991-12-01 00:00:00

abstract：:The effect of bile on the expression of cholera toxin (CT) and the major subunit of the toxin-coregulated pilus (TcpA) and on motility was examined in the Vibrio cholerae O1 classical-biotype strains 0395 and 569B. Although the motility of the cells increased significantly in the presence of bile, transcription of the...

journal_title：Infection and immunity

authors： Gupta S,Chowdhury R

更新日期：1997-03-01 00:00:00

abstract：:Mucosa-associated invariant T (MAIT) cells are an innate-like T cell subset in mammals that recognize microbial vitamin B metabolites presented by the evolutionarily conserved major histocompatibility complex class I (MHC I)-related molecule, MR1. Emerging data suggest that MAIT cells may be an attractive target for v...

journal_title：Infection and immunity

authors： Vorkas CK,Levy O,Skular M,Li K,Aubé J,Glickman MS

更新日期：2020-12-15 00:00:00

abstract：:Natural killer (NK) cells are critically involved in the early immune response against various intracellular pathogens, including Coxiella burnetii and Chlamydia psittaciChlamydia-infected NK cells functionally mature, induce cellular immunity, and protect themselves by killing the bacteria in secreted granules. Here,...

journal_title：Infection and immunity

authors： Matthiesen S,Zaeck L,Franzke K,Jahnke R,Fricke C,Mauermeir M,Finke S,Lührmann A,Knittler MR

更新日期：2020-10-19 00:00:00

abstract：:Streptococcus pneumoniae contains an inhibitor of human neutrophil elastase. The agent does not inhibit other proteases, including neutrophil cathepsin G and pancreatic elastase. It is active in the presence of insoluble elastin as well as synthetic elastase substrates. The inhibitor is present in the pneumococcal cel...

journal_title：Infection and immunity

authors： Vered M,Simon SR,Janoff A

更新日期：1985-07-01 00:00:00

abstract：:A total of 133 Listeria monocytogenes isolates were characterized by ribotyping and allelic analysis of the virulence genes hly, actA, and inlA to uncover linkages between independent phylogenetic and specific virulence markers. PCR-restriction fragment length polymorphisms revealed 8 hly, 11 inl4, and 2 actA alleles....

journal_title：Infection and immunity

authors： Wiedmann M,Bruce JL,Keating C,Johnson AE,McDonough PL,Batt CA

更新日期：1997-07-01 00:00:00