Interaction of Aspergillus fumigatus Spores with Human Leukocytes and Serum.

abstract：:Despite the autotransporter (AT) moniker, AT secretion appears to involve the function of periplasmic chaperones. We identified four periplasmic proteins that specifically bound to plasmid-encoded toxin (Pet), an AT produced by enteroaggregative Escherichia coli (EAEC). These proteins include the 17-kDa Skp chaperone ...

journal_title：Infection and immunity

authors： Tapia-Pastrana G,Chavez-Dueñas L,Lanz-Mendoza H,Teter K,Navarro-García F

更新日期：2012-07-01 00:00:00

abstract：:Strain differences have been postulated to explain the observation that group B Streptococcus type III (GBS III) late-onset disease occurs in only a fraction of colonized infants. To determine the distribution of type-specific polysaccharide antigen (Ag) in GBS III, Ag was measured by rocket immunoelectrophoresis in b...

journal_title：Infection and immunity

authors： Klegerman ME,Boyer KM,Papierniak CK,Levine L,Gotoff SP

更新日期：1984-04-01 00:00:00

abstract：:Helicobacter pylori mutants deficient in 6-phosphogluconate dehydratase (6PGD) were constructed. Colonization densities were lower and minimum infectious doses were higher for mutant strains than for wild-type strains. In spite of better colonization, however, wild-type strains did not displace the mutant in cocoloniz...

journal_title：Infection and immunity

authors： Wanken AE,Conway T,Eaton KA

更新日期：2003-05-01 00:00:00

abstract：:Splenic lymphocytes from cytomegalovirus-infected mice lost their in vitro proliferative responses to cytomegalovirus antigen within 3 h after in vivo treatment with antilymphocyte globulin and prednisolone. The response was inhibited when the agents were administered separately or together, and inhibition persisted t...

journal_title：Infection and immunity

authors： Mattsson DM,Howard RJ,Balfour HH Jr

更新日期：1980-12-01 00:00:00

abstract：:The listeriolysin gene from a weakly hemolytic but virulent strain of Listeria monocytogenes serotype 1/2a was cloned in Escherichia coli K-12. Recombinants were identified on the basis of their cross-reactivities to hyperimmune antisera raised against streptolysin O and listeriolysin. Low levels of hemolytic activity...

journal_title：Infection and immunity

authors： Leimeister-Wächter M,Chakraborty T

更新日期：1989-08-01 00:00:00

abstract：:The effects of pathologically relevant concentrations (0.38 to 12.5 microM) of the proinflammatory, Pseudomonas aeruginosa-derived pigment 1-hydroxyphenazine (1-hp) on Ca2+ metabolism and intracellular cyclic AMP (cAMP) in N-formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP; 1 microM)-activated human neutrophils, as w...

journal_title：Infection and immunity

authors： Ramafi G,Anderson R,Theron A,Feldman C,Taylor GW,Wilson R,Cole PJ

更新日期：1999-10-01 00:00:00

abstract：:Mice were rendered deficient in B-cell activity by treatment with anti-mu antibody from birth. These animals were then infected intranasally with murine Chlamydia trachomatis (murine pneumonitis agent [MoPn]). They produced neither local nor systemic antibody to MoPn but had intact delayed-type hypersensitivity to MoP...

journal_title：Infection and immunity

authors： Williams DM,Grubbs B,Schachter J

更新日期：1987-10-01 00:00:00

abstract：:Pneumolysin (PLY), an important virulence factor of Streptococcus pneumoniae, is known to exert various effects on the host immune cells, including cytokine induction, in addition to its known cytolytic activity as a member of the thiol-activated cytolysins. It is of interest to determine whether cytolytic activity is...

journal_title：Infection and immunity

authors： Baba H,Kawamura I,Kohda C,Nomura T,Ito Y,Kimoto T,Watanabe I,Ichiyama S,Mitsuyama M

更新日期：2002-01-01 00:00:00

abstract：:Lipid extracts derived from a group A Streptococcus, when preincubated with tumor cells before inoculation, were shown to prevent completely the development of Ehrlich ascites tumor in mice. ...

journal_title：Infection and immunity

authors： Kigoshi S

更新日期：1971-05-01 00:00:00

abstract：:Neisseria gonorrhoeae is generally considered to be an obligate aerobe; it can, however, grow in the absence of oxygen by anaerobic respiration by using nitrite as a terminal electron acceptor. The outer membrane protein compositions of aerobically and anaerobically grown N. gonorrhoeae strains were compared by one- a...

journal_title：Infection and immunity

authors： Clark VL,Campbell LA,Palermo DA,Evans TM,Klimpel KW

更新日期：1987-06-01 00:00:00

abstract：:Attaching and effacing adhesion to epithelial cells is a pathognomonic feature of infection by both enteropathogenic Escherichia coli (EPEC) and certain strains of verocytotoxin-producing E. coli (VTEC). EPEC adhesion to tissue culture epithelial cells results in activation of the phosphatidylinositol pathway, with el...

journal_title：Infection and immunity

authors： Ismaili A,Philpott DJ,Dytoc MT,Sherman PM

更新日期：1995-09-01 00:00:00

abstract：:Mice given Mycobacterium tuberculosis bacilli via the respiratory route succumbed much sooner to infection than mice given 1,000 times more bacilli via the intravenous route. Vaccination provided increased protection to an M. tuberculosis challenge infection; however, mice infected via the respiratory route remained m...

journal_title：Infection and immunity

authors： North RJ,LaCourse R,Ryan L

更新日期：1999-04-01 00:00:00

abstract：:The Salmonella typhimurium gene for Mn-cofactored superoxide dismutase (sodA) was cloned by complementation of an Escherichia coli sodA sodB mutant for growth on minimal medium. Sequence analysis revealed an open reading frame of 618 bp encoding a polypeptide with 97% identity to E. coli SodA. A S. typhimurium sodA mu...

journal_title：Infection and immunity

authors： Tsolis RM,Bäumler AJ,Heffron F

更新日期：1995-05-01 00:00:00

abstract：:The immune response to the mycobacterial 65-kDa heat shock protein (hsp65) is considered an important event in the induction of adjuvant arthritis (AA) in rats; this induction probably occurs through a molecular mimicry mechanism involving cross-reactivity against the rat homolog hsp60. To analyze the role of mammalia...

journal_title：Infection and immunity

authors： López-Guerrero JA,López-Bote JP,Ortiz MA,Gupta RS,Páez E,Bernabeu C

更新日期：1993-10-01 00:00:00

abstract：:The ability of a pathogen to evade neutrophil phagocytic killing mechanisms is critically important for dissemination and establishment of a systemic infection. Understanding how pathogens overcome these innate defenses is essential for the development of optimal therapeutic strategies for invasive infections. CpsY is...

journal_title：Infection and immunity

authors： Allen JP,Neely MN

更新日期：2012-05-01 00:00:00

abstract：:Salivary proline-rich proteins (PRPs), which were purified from parotid saliva, were adsorbed onto 15-nm-diameter gold particles to visualize specific binding of the salivary molecules to Actinomyces viscosus type 1 fimbriae. Negatively stained preparations incubated with PRP-gold conjugates but not bovine serum album...

journal_title：Infection and immunity

authors： Leung KP,Nesbitt WE,Fischlschweiger W,Hay DI,Clark WB

更新日期：1990-06-01 00:00:00

abstract：:Bacterial tyrosine kinases and their cognate protein tyrosine phosphatases are best known for regulating the biosynthesis of polysaccharides. Moreover, their roles in the stress response, DNA metabolism, cell division, and virulence have also been documented. The aim of this study was to investigate the pathogenicity ...

journal_title：Infection and immunity

authors： Ferreira AS,Silva IN,Fernandes F,Pilkington R,Callaghan M,McClean S,Moreira LM

更新日期：2015-02-01 00:00:00

abstract：:Immunity to pneumococcal colonization in mice by exposure to live or killed pneumococci has been shown to be antibody independent but dependent on CD4+ T cells. Here we show that intranasal immunization with pneumococcal proteins (pneumococcal surface protein C, adhesin A, and a pneumolysoid) can elicit a similar mech...

journal_title：Infection and immunity

authors： Basset A,Thompson CM,Hollingshead SK,Briles DE,Ades EW,Lipsitch M,Malley R

更新日期：2007-11-01 00:00:00

abstract：:Pathogenic leptospires have the ability to survive and disseminate to multiple organs after penetrating the host. Several pathogens, including spirochetes, have been shown to express surface proteins that interact with the extracellular matrix (ECM). This adhesin-mediated binding process seems to be a crucial step in ...

journal_title：Infection and immunity

authors： Barbosa AS,Abreu PA,Neves FO,Atzingen MV,Watanabe MM,Vieira ML,Morais ZM,Vasconcellos SA,Nascimento AL

更新日期：2006-11-01 00:00:00

abstract：:Antibody to Pseudomonas aeruginosa exotoxin was detected in human sera by using a cytotoxicity-neutralization assay. Serum antitoxin was present in high titer in all 14 patients who recovered from serious pseudomonas infections (log2 of 50% neutralization titer, mean +/- standard deviation = 6.0 +/- 1.2). In contrast,...

journal_title：Infection and immunity

authors： Pollack M,Callahan LT 3rd,Taylor NS

更新日期：1976-10-01 00:00:00

abstract：:Attention has recently been focused on immunoglobulin A1 (IgA1) protease production as a possible virulence factor of bacteria implicated in meningitis and gonorrhea. This report demonstrates that suspected principal etiological agents in destructive periodontal disease include bacteria capable of degrading IgA1, IgA2...

journal_title：Infection and immunity

authors： Kilian M

更新日期：1981-12-01 00:00:00

abstract：:The adherence of Treponema denticola GM-1, TD-4, and MS25 to human gingival fibroblasts (HGFs) was studied to serve as an introduction to investigations into the interactions of these oral bacteria with human host cells. Under both aerobic (5% CO2) and anaerobic (85% N2 plus 10% H2 plus 5% CO2) environments, the inter...

journal_title：Infection and immunity

authors： Weinberg A,Holt SC

更新日期：1990-06-01 00:00:00

abstract：:The mechanism of adsorption of the Streptococcus mutans enzymes responsible for the synthesis of insoluble dextran-levan to the S. mutans cell-wall binding sites has been studied. Certain characteristics of these binding sites are presented. The adsorption of these enzymes to the cell surface occurred rapidly without ...

journal_title：Infection and immunity

authors： Mukasa H,Slade HD

更新日期：1974-02-01 00:00:00

abstract：:Since we previously observed a remarkable decrease in the numbers of T cells in the Peyer's patches of the small intestines in C57BL/6 mice following peroral infection with Toxoplasma gondii, we performed studies to examine the mechanism(s) whereby this decrease in numbers of the T cells occurs. We found that apoptoti...

journal_title：Infection and immunity

authors： Liesenfeld O,Kosek JC,Suzuki Y

更新日期：1997-11-01 00:00:00

abstract：:Surface proteins in gram-positive bacteria are frequently required for virulence, and many are attached to the cell wall by sortase enzymes. Bacteria frequently encode more than one sortase enzyme and an even larger number of potential sortase substrates that possess an LPXTG-type cell wall sorting signal. In order to...

journal_title：Infection and immunity

authors： Comfort D,Clubb RT

更新日期：2004-05-01 00:00:00

abstract：:Infectious agents are often considered potential triggers of chronic inflammatory disease, including autoimmunity; however, direct evidence is usually lacking. Here we show that following control of acute infection of mice with the myotropic Colombiana strain of Trypanosoma cruzi, parasites persisted in tissue at low ...

journal_title：Infection and immunity

authors： Roffê E,Marino APMP,Weaver J,Wan W,de Araújo FF,Hoffman V,Santiago HC,Murphy PM

更新日期：2016-03-24 00:00:00

abstract：:Escherichia coli C25 maintained population levels of 10(9) to 10(10) per g of cecum and translocated to 100% of the middle mesenteric lymph nodes in gnotobiotic mice monoassociated with E. coli C25. Intragastric inoculation of these mice with the cecal contents from specific-pathogen-free mice reduced the population l...

journal_title：Infection and immunity

authors： Berg RD

更新日期：1980-09-01 00:00:00

abstract：:Actinobacillus pleuropneumoniae, the causative agent of swine pleuropneumonia, secretes a hemolytic activity which is thought to be a factor involved in the pathogenesis of the disease. The biosynthesis of hemolysin by serotype 1 strain 4074 was strongly dependent on the activity of free Ca2+ in the growth medium. At ...

journal_title：Infection and immunity

authors： Frey J,Nicolet J

更新日期：1988-10-01 00:00:00

abstract：:Various factors affecting the aggregation of Actinomyces naeslundii strain 12104 were studied. When the pH of glucose-supplemented growth medium fell below 5.5, the cells aggregated and formed microbial masses which tenaciously adhered to the culture vessels. When the organism was cultured in the same medium in the ab...

journal_title：Infection and immunity

authors： Miller CH,Palenik CJ,Stamper KE

更新日期：1978-09-01 00:00:00

abstract：:The screening of several inbred strains of mice suggested that the capacity of their spleen cells to respond to the mitogenic effect of lipopolysaccharide (LPS) of gram-negative bacteria was correlated with their resistance to intraperitoneal infection with Salmonella typhimurium. An infection of LPS into mice caused ...

journal_title：Infection and immunity

authors： von Jeney N,Günther E,Jann K

更新日期：1977-01-01 00:00:00