Degradation of immunoglobulins A2, A2, and G by suspected principal periodontal pathogens.

abstract：:A previously undescribed, immunoreactive, membranous spherule outer wall (SOW) fraction produced by Coccidioides immitis (strains 634 and 735) grown in culture was isolated. Both this fraction and intact spherules were reactive with sera from coccidioidomycosis patients, as demonstrated by immunofluorescence microscop...

journal_title：Infection and immunity

authors： Cole GT,Seshan KR,Franco M,Bukownik E,Sun SH,Hearn VM

更新日期：1988-10-01 00:00:00

abstract：:Neonatal animals are generally very susceptible to infection with bacterial pathogens. However, we recently reported that neonatal mice are highly resistant to orogastric infection with Yersinia enterocolitica. Here, we show that proinflammatory responses greatly exceeding those in adults arise very rapidly in the mes...

journal_title：Infection and immunity

authors： Siefker DT,Echeverry A,Brambilla R,Fukata M,Schesser K,Adkins B

更新日期：2014-02-01 00:00:00

abstract：:Legionella pneumophila multiplied rapidly in guinea pig and rat alveolar macrophages but failed to grow when phagocytic activity was inhibited by pretreatment with 0.5 or 1.0 microgram of cytochalasin D per ml. Attachment was not inhibited by cytochalasin D. No extracellular multiplication occurred when L. pneumophila...

journal_title：Infection and immunity

authors： Elliott JA,Winn WC Jr

更新日期：1986-01-01 00:00:00

abstract：:Burkholderia cenocepacia strain K56-2 typically has rough colony morphology on agar medium; however, shiny colony variants (shv) can appear spontaneously. These shv all had a minimum of 50% reduction in biomass formation and were generally avirulent in an alfalfa seedling infection model. Three shv-K56-2 S15, K56-2 S7...

journal_title：Infection and immunity

authors： Bernier SP,Nguyen DT,Sokol PA

更新日期：2008-01-01 00:00:00

abstract：:This work evaluated the kinetics of events that occur in the placenta of Calomys callosus after Toxoplasma gondii infection. Animals on the first day of pregnancy (dop) and virgin nonpregnant females were perorally infected with 20 cysts of T. gondii strain ME49. After 100 days of infection, the virgin animals were ma...

journal_title：Infection and immunity

authors： Ferro EA,Silva DA,Bevilacqua E,Mineo JR

更新日期：2002-12-01 00:00:00

abstract：:Type IV pili (Tfp) of gram-negative species share many characteristics, including a common architecture and conserved biogenesis pathway. Much less is known about the regulation of Tfp expression in response to changing environmental conditions. We investigated the diversity of Tfp regulatory systems by searching for ...

journal_title：Infection and immunity

authors： Boekema BK,Van Putten JP,Stockhofe-Zurwieden N,Smith HE

更新日期：2004-02-01 00:00:00

abstract：:Newly hatched chicks were vaccinated orally with a genetically defined Salmonella enteritidis aroA candidate, strain CVL30. In chickens immunized with 10(5) or 10(9) CFU and challenged by the intravenous route with 10(8) CFU of S. enteritidis 109 Nalr at 8 weeks old, there were similar reductions in colonization of th...

journal_title：Infection and immunity

authors： Cooper GL,Venables LM,Woodward MJ,Hormaeche CE

更新日期：1994-11-01 00:00:00

abstract：:Toxoplasma gondii is an obligate intracellular parasite that resides in the cytoplasm of its host in a unique membrane-bound vacuole known as the parasitophorous vacuole (PV). The membrane surrounding the parasite is remodeled by the dense granules, secretory organelles that release an array of proteins into the vacuo...

journal_title：Infection and immunity

authors： Rome ME,Beck JR,Turetzky JM,Webster P,Bradley PJ

更新日期：2008-11-01 00:00:00

abstract：:The mechanism of adsorption of the Streptococcus mutans enzymes responsible for the synthesis of insoluble dextran-levan to the S. mutans cell-wall binding sites has been studied. Certain characteristics of these binding sites are presented. The adsorption of these enzymes to the cell surface occurred rapidly without ...

journal_title：Infection and immunity

authors： Mukasa H,Slade HD

更新日期：1974-02-01 00:00:00

abstract：:The immunopathology of Chagas' disease was studied in the experimental model of chronic infection in C57BL/10JT or mice. Sublethal infection with Trypanosoma cruzi, Y strain, induced specific antibodies and a delayed hypersensitivity response to parasite antigens. Mice developed chronic chagasic myocarditis but not sk...

journal_title：Infection and immunity

authors： Mortatti RC,Maia LC,de Oliveira AV,Munk ME

更新日期：1990-11-01 00:00:00

abstract：:Neisseria meningitidis crosses the blood-brain barrier (BBB) following the activation of the β2-adrenergic receptor by the type IV pili (TFP). Two components of the type IV pili recruit the β2-adrenergic receptor, the major pilin PilE and the minor pilin PilV. Here, we report that a strain deleted of PilX, one of the ...

journal_title：Infection and immunity

authors： Brissac T,Mikaty G,Duménil G,Coureuil M,Nassif X

更新日期：2012-09-01 00:00:00

abstract：:Capsular types 5 and 8, which account for about 70% of Staphylococcus aureus strains isolated from the blood of patients, resisted in vitro phagocytosis by human polymorphonuclear leukocytes (PMN). Antisera and monoclonal antibody to type 5 and 8 capsular polysaccharides (CPS) induced type-specific in vitro phagocytos...

journal_title：Infection and immunity

authors： Karakawa WW,Sutton A,Schneerson R,Karpas A,Vann WF

更新日期：1988-05-01 00:00:00

abstract：:Current efforts to develop plague vaccines focus on LcrV, a polypeptide that resides at the tip of type III secretion needles. LcrV-specific antibodies block Yersinia pestis type III injection of Yop effectors into host immune cells, thereby enabling phagocytes to kill the invading pathogen. Earlier work reported that...

journal_title：Infection and immunity

authors： Miller NC,Quenee LE,Elli D,Ciletti NA,Schneewind O

更新日期：2012-04-01 00:00:00

abstract：:In this study, the efficacy of bactericidal/permeability-increasing protein (BPI) was assessed in a rat model of chronic otitis media with effusion. BPI injection prevented disturbance of the mucociliary clearance system of the middle ear. Hence, it is postulated that BPI can be a new therapy for chronic otitis media ...

journal_title：Infection and immunity

authors： Nell MJ,Koerten HK,Grote JJ

更新日期：2000-05-01 00:00:00

abstract：:Erythrocytic malaria parasites degrade hemoglobin as a principal source of amino acids for parasite protein synthesis. We have previously shown that a Plasmodium falciparum trophozoite cysteine proteinase, now termed falcipain, is required for hemoglobin degradation, and we have hypothesized that this proteinase is re...

journal_title：Infection and immunity

authors： Salas F,Fichmann J,Lee GK,Scott MD,Rosenthal PJ

更新日期：1995-06-01 00:00:00

abstract：:Feto-placental infections represent a major cause of pregnancy complications, and yet the underlying molecular and cellular mechanisms of vertical transmission are poorly understood. Listeria monocytogenes, a facultative intracellular pathogen, is one of a group of pathogens that are known to cause feto-placental infe...

journal_title：Infection and immunity

authors： Bakardjiev AI,Stacy BA,Fisher SJ,Portnoy DA

更新日期：2004-01-01 00:00:00

abstract：:We developed an in vitro model to study the temperature-regulated cytotoxicity and intracellular growth of Mycobacterium haemophilum in cultured human epithelial and endothelial cells. M. haemophilum associated with human epithelial and endothelial cells at similar rates when incubated at 33 and 37 degrees C, but only...

journal_title：Infection and immunity

authors： Fischer LJ,Quinn FD,White EH,King CH

更新日期：1996-01-01 00:00:00

abstract：:Strains H37Ra and H37Rv, attenuated and virulent variants, respectively, of the original human strain H37 of Mycobacterium tuberculosis, were used to infect cultures of mouse peritoneal macrophages. Bacterial viability of each strain was assessed over a 2-week period, and the cellular response to H37Ra during the firs...

journal_title：Infection and immunity

authors： Hart PD,Armstrong JA

更新日期：1974-10-01 00:00:00

abstract：:K99 prepared by acid precipitation hemagglutinated guinea pig erythrocytes, whereas K99 prepared by chromatography on diethylaminoethyl-Sephadex did not. K99 purified by either procedure hemagglutinated horse erythrocytes. K99 prepared by acid precipitation contained a second antigen not presnet in the K99 prepared by...

journal_title：Infection and immunity

authors： Isaacson RE

更新日期：1978-11-01 00:00:00

abstract：:Clostridium botulinum neurotoxins (BoNTs) are the most toxic proteins for humans. The current clostridial-derived vaccines against BoNT intoxication have limitations including production and accessibility. Conditions were established to express the soluble receptor binding domain (heavy-chain receptor [HCR]) of BoNT s...

journal_title：Infection and immunity

authors： Baldwin MR,Tepp WH,Pier CL,Bradshaw M,Ho M,Wilson BA,Fritz RB,Johnson EA,Barbieri JT

更新日期：2005-10-01 00:00:00

abstract：:The chromosomal iroBCDEN gene cluster first described for Salmonella enterica is involved in the uptake of catecholate-type siderophore compounds. An orthologous gene cluster has recently been detected in Escherichia coli strains which cause extraintestinal disease. This E. coli iroBCDEN gene cluster has an impact on ...

journal_title：Infection and immunity

authors： Sorsa LJ,Dufke S,Heesemann J,Schubert S

更新日期：2003-06-01 00:00:00

abstract：:Binding of radiolabeled human fibrinogen and aggregated beta-microglobulin was measured in 60 strains of beta-hemolytic group B streptococci. Positive fibrinogen binding was detected in seven of the strains. Six of the group B strains showed an uptake of aggregated beta 2-microglobulin. Four individual strains carried...

journal_title：Infection and immunity

authors： Schönbeck C,Björck L,Kronvall G

更新日期：1981-03-01 00:00:00

abstract：:Treatment of Rickettsia prowazekii-infected L929 cells with gamma interferon (IFN-gamma) immediately after infection altered the lipid metabolism of the host cells as determined by measurement of phospholipid hydrolysis and oleic acid incorporation into phospholipids and neutral lipids. At 48 h postinfection, there wa...

journal_title：Infection and immunity

authors： Winkler HH,Day L,Daugherty R,Turco J

更新日期：1993-08-01 00:00:00

abstract：:The mechanism by which recombinant murine gamma interferon (rMuIFN-gamma) and bacterial lipopolysaccharide (LPS) activate mouse resident splenic macrophages to inhibit the intracellular growth of the fungus Histoplasma capsulatum was examined. Growth inhibition depended on L-arginine metabolism. The growth inhibitory ...

journal_title：Infection and immunity

authors： Lane TE,Wu-Hsieh BA,Howard DH

更新日期：1994-05-01 00:00:00

abstract：:In order to further understand Epstein-Barr virus (EBV)-lymphocyte interactions, we investigated a chain of events including: (i) EBV binding to human lymphocyte subpopulations; (ii) the earliest appearance of EBV-determined nuclear antigen (EBNA) in the lymphocytes after EBV infection; and (iii) establishment of cont...

journal_title：Infection and immunity

authors： Menezes J,Jondal M,Leibold W,Dorval G

更新日期：1976-02-01 00:00:00

abstract：:Group A streptococcal pyrogenic exotoxins A, B, and C (also known as scarlet fever toxins and erythrogenic toxins) were evaluated for relatedness to another streptococcus-derived lymphocyte mitogen, blastogen A. Streptococcal pyrogenic exotoxin A and blastogen A were immunologically cross-reactive and shared the same ...

journal_title：Infection and immunity

authors： Schlievert PM,Gray ED

更新日期：1989-06-01 00:00:00

abstract：:Nonopsonic invasion of mononuclear phagocytes by Mycobacterium tuberculosis is likely important in the establishment of a primary infection in the lung. M. tuberculosis binds to a variety of phagocyte receptors, of which the mannose receptor and complement receptor type 3 (CR3) may support nonopsonic binding. CR3, a b...

journal_title：Infection and immunity

authors： Cywes C,Godenir NL,Hoppe HC,Scholle RR,Steyn LM,Kirsch RE,Ehlers MR

更新日期：1996-12-01 00:00:00

abstract：:Amastigotes obtained from spleens of mice infected with different strains of Trypanosoma cruzi were examined for their ability to invade macrophages and L929 cells and to initiate infection in mice. Both types of cells were readily invaded by organisms of the strains Y, MR, and Tulahuen. Organisms of the CL strain wer...

journal_title：Infection and immunity

authors： McCabe RE,Remington JS,Araujo FG

更新日期：1984-11-01 00:00:00

abstract：:Mycobacterium marinum grows at an optimal temperature of 33 degrees C, far lower than that for M. tuberculosis. Consequently, M. marinum infection of mammals is restricted largely to the cooler surfaces of the body, such as the extremities, but it causes a systemic infection in a large number of poikilothermic animals...

journal_title：Infection and immunity

authors： Ramakrishnan L,Valdivia RH,McKerrow JH,Falkow S

更新日期：1997-02-01 00:00:00

abstract：:Contributions of the alternative sigma factor sigmaB to Listeria monocytogenes infection were investigated using strains bearing null mutations in sigB, prfA, or inlA or in selected inlA or prfA promoter regions. The DeltaP4inlA strain, which has a deletion in the sigmaB-dependent P4inlA promoter, and the DeltasigB st...

journal_title：Infection and immunity

authors： Garner MR,Njaa BL,Wiedmann M,Boor KJ

更新日期：2006-02-01 00:00:00