The innate immune response to Salmonella enterica serovar Typhimurium by macrophages is dependent on TREM2-DAP12.

abstract：:The effects of heat and chemical inactivation on the antigenicity and immunogenicity of Vibrio cholerae 1418 in rabbits were studied. V. cholerae 1418 was inactivated with heat and chemical inactivants (phenol or Formalin) alone or in combination. Enzyme-linked immunoassay systems employing whole cells of V. cholerae ...

journal_title：Infection and immunity

authors： Cryz SJ Jr,Fürer E,Germanier R

更新日期：1982-10-01 00:00:00

abstract：:Inactivated Marek's disease virus-infected chicken kidney cells and inactivated MSB-1 lymphoblastoid Marek's disease tumor cells were used to immunize chickens as virus- and tumor-associated antigens, respectively. Immune and nonimmune birds were then challenged by exposure to live virulent Marek's disease virus. Both...

journal_title：Infection and immunity

authors： Murthy KK,Calnek BW

更新日期：1979-11-01 00:00:00

abstract：:Adoptive immunity is poorly expressed in normal syngeneic mice. This phenomenon was studied by using experimental antituberculosis immunity as a model system representing pure cell-mediated immunity. Expression of adoptive immunity was facilitated by pretreating recipients with sublethal ionizing radiation (500 rads) ...

journal_title：Infection and immunity

authors： Lefford MJ

更新日期：1983-07-01 00:00:00

abstract：:We have identified a Crp/Fnr-like transcriptional regulator of Streptococcus pyogenes that when inactivated attenuates virulence. The gene, named srv for streptococcal regulator of virulence, encodes a 240-amino-acid protein with 53% amino acid similarity to PrfA, a transcriptional activator of virulence in Listeria m...

journal_title：Infection and immunity

authors： Reid SD,Montgomery AG,Musser JM

更新日期：2004-03-01 00:00:00

abstract：:Encapsulation of soluble protein antigens in liposomes was previously shown to result in processing of antigen via the major histocompatibility complex class I pathway, as evidenced by costaining of the trans-Golgi region of murine bone marrow-derived macrophages (BMs) by fluorophore-labeled liposomal antigen and by a...

journal_title：Infection and immunity

authors： Richards RL,Rao M,Wassef NM,Glenn GM,Rothwell SW,Alving CR

更新日期：1998-06-01 00:00:00

abstract：:Clostridium difficile toxins A and B (TcdA and TcdB) are the causative agents of antibiotic-associated pseudomembranous colitis. Mucosal mast cells play a crucial role in the inflammatory processes underlying this disease. We studied the direct effects of TcdA and TcdB on the human mast cell line HMC-1 with respect to...

journal_title：Infection and immunity

authors： Meyer GK,Neetz A,Brandes G,Tsikas D,Butterfield JH,Just I,Gerhard R

更新日期：2007-08-01 00:00:00

abstract：:Metastatic infection after hematogenous dissemination of Candida species is presumably dependent on the fungus traversing the vascular endothelium. An in vitro model of the earliest events of metastatic Candida infection was developed with whole vascular strips. Freshly obtained porcine blood vessels were secured in a...

journal_title：Infection and immunity

authors： Klotz SA,Drutz DJ,Harrison JL,Huppert M

更新日期：1983-10-01 00:00:00

abstract：:Neisseria meningitidis is a human-specific pathogen and leading cause of meningitis and septicemia. Factor H binding protein (fHbp), a virulence factor which protects N. meningitidis from innate immunity by binding the human complement regulator factor H (fH) with high affinity, is also a key antigen in vaccines being...

journal_title：Infection and immunity

authors： van der Veen S,Johnson S,Jongerius I,Malik T,Genovese A,Santini L,Staunton D,Ufret-Vincenty RL,Pickering MC,Lea SM,Tang CM

更新日期：2014-03-01 00:00:00

abstract：:Stimulation of the rabbit reticuloendothelial system with viable Mycobacterium bovis (strain BCG), and other agents, had no effect on the development of syphilitic lesions after intradermal or intravenous inoculation with graded doses of Treponema pallidum (virulent Nichol's strain; mean infective doses less than 10)....

journal_title：Infection and immunity

authors： Graves SR,Johnson RC

更新日期：1975-11-01 00:00:00

abstract：:Gamma interferon (IFN-gamma) is produced in response to circulating lipopolysaccharide (LPS) and contributes to the lethality of endotoxic shock. To address the cellular source of IFN-gamma production in vivo, T cells and B cells were magnetically purified from C57BL/6 mouse spleens 5 h following endotoxin injection. ...

journal_title：Infection and immunity

authors： Heinzel FP,Rerko RM,Ling P,Hakimi J,Schoenhaut DS

更新日期：1994-10-01 00:00:00

abstract：:A high-molecular-weight, immunogenic form of the lipopolysaccharide O side chain of Pseudomonas aeruginosa Fisher immunotype 4 (type 4, International Antigenic Typing System 1, Lanyi O:6) was isolated and characterized. Analysis by nuclear magnetic resonance spectroscopy confirmed the structural similarity of this hig...

journal_title：Infection and immunity

authors： Pier GB,Pollack M

更新日期：1989-02-01 00:00:00

abstract：:The region of DNA encoding the mannose-fucose-resistant hemagglutinin (MFRHA) of Vibrio cholerae O1 has been localized, and the nucleotide sequence has been determined. The region contains a single open reading frame encoding 230 amino acids, corresponding to a protein of 26.9 kDa. The N terminus of this protein is at...

journal_title：Infection and immunity

authors： Franzon VL,Barker A,Manning PA

更新日期：1993-07-01 00:00:00

abstract：:Cell-mediated immunity plays an important role in immunity to the pathogenic fungus Cryptococcus neoformans. However, the antigen specificity of the T-cell response to C. neoformans remains largely unknown. In this study, we used two approaches to determine the antigen specificity of the T-cell response to C. neoforma...

journal_title：Infection and immunity

authors： Lindell DM,Ballinger MN,McDonald RA,Toews GB,Huffnagle GB

更新日期：2006-08-01 00:00:00

abstract：:The comparative immunogenicity of the two cross-reacting group 6 pneumococcal capsular polysaccharides, type 6A(6) and type 6B(26), was studied with hyperimmune rabbit typing antisera and with sera from adult volunteers injected with polyvalent pneumococcal vaccines containing either 50 mug of type 6A (U.S. designatio...

journal_title：Infection and immunity

authors： Robbins JB,Lee CJ,Rastogi SC,Schiffman G,Henrichsen J

更新日期：1979-12-01 00:00:00

abstract：:Protective immunity to Plasmodium falciparum malaria acquired after natural exposure is largely antibody mediated. IgG-specific P. falciparum EMP1 (PfEMP1) proteins on the infected erythrocyte surface are particularly important. The transient antibody responses and the slowly acquired protective immunity probably refl...

journal_title：Infection and immunity

authors： Ampomah P,Stevenson L,Ofori MF,Barfod L,Hviid L

更新日期：2014-05-01 00:00:00

abstract：:Guinea pig and mouse peritoneal macrophages in culture transport glucose by a specific, saturable system with characteristics compatible with facilitated diffusion. Phagocytosis of killed staphylococci or polystyrene latex spheres results in a significant increase in uptake of 2-deoxy-d-glucose. Reciprocal plot analys...

journal_title：Infection and immunity

authors： Bonventre PF,Mukkada AJ

更新日期：1974-12-01 00:00:00

abstract：:Helicobacter pylori is an important human pathogen that causes gastritis and is strongly associated with gastric ulcers, gastric adenocarcinomas, and mucosa-associated lymphoid tissue lymphomas. In response to H. pylori, interleukin-8 (IL-8) is secreted from host cells to attract components of the innate and adaptive ...

journal_title：Infection and immunity

authors： Torok AM,Bouton AH,Goldberg JB

更新日期：2005-03-01 00:00:00

abstract：:Rabbit-specific enteropathogenic Escherichia coli (REPEC) is an attaching and effacing pathogen of young rabbits. Using signature-tagged mutagenesis, we identified several known colonization factors of REPEC as well as a gene predicted to encode a novel autotransporter protein. This novel gene was termed rpeA for REPE...

journal_title：Infection and immunity

authors： Leyton DL,Adams LM,Kelly M,Sloan J,Tauschek M,Robins-Browne RM,Hartland EL

更新日期：2007-09-01 00:00:00

abstract：:The predominant gram-positive bacteria in 47 fecal specimens from 10 healthy men were studied by microscopic and cultural counts, by the characterization and tentative identification of isolates, and by the use of fluorescein isothiocyanate (FITC)-conjugated globulins prepared using some of the isolates. Gram-positive...

journal_title：Infection and immunity

authors： Gossling J,Slack JM

更新日期：1974-04-01 00:00:00

abstract：:Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that other mechanisms of vir...

journal_title：Infection and immunity

authors： McClelland EE,Perrine WT,Potts WK,Casadevall A

更新日期：2005-10-01 00:00:00

abstract：:Susceptibility to Coccidioides spp. varies widely in humans and other mammals and also among individuals within a species. Among strains of mice with various susceptibilities, immunohistopathology revealed that C57BL/6 mice were highly susceptible to the disease following intranasal infection, DBA/2n mice were interme...

journal_title：Infection and immunity

authors： Shubitz LF,Dial SM,Perrill R,Casement R,Galgiani JN

更新日期：2008-12-01 00:00:00

abstract：:The effect of iron concentration during growth on the physicochemical surface properties of the colonial variants of Neisseria gonorrhoeae has been assessed by aqueous two-phase partitioning in a dextran-polyethyleneglycol system containing positively charged trimethylamino-polyethyleneglycol or hydrophobic polyethyle...

journal_title：Infection and immunity

authors： Magnusson KE,Kihlstrom E,Norqvist A,Davies J,Normark S

更新日期：1979-11-01 00:00:00

abstract：:Pathogenic leptospires have the ability to survive and disseminate to multiple organs after penetrating the host. Several pathogens, including spirochetes, have been shown to express surface proteins that interact with the extracellular matrix (ECM). This adhesin-mediated binding process seems to be a crucial step in ...

journal_title：Infection and immunity

authors： Barbosa AS,Abreu PA,Neves FO,Atzingen MV,Watanabe MM,Vieira ML,Morais ZM,Vasconcellos SA,Nascimento AL

更新日期：2006-11-01 00:00:00

abstract：:Lipoteichoic acids (LTAs) belong to the immunostimulatory class of molecules of gram-positive bacteria (GPB). Previous investigations showed that the macrophage scavenger receptor (SR), a glycosylated trimeric transmembrane protein, binds directly to many GPB, possibly via LTA. SR binding to other ligands is dependent...

journal_title：Infection and immunity

authors： Greenberg JW,Fischer W,Joiner KA

更新日期：1996-08-01 00:00:00

abstract：:Evidence showing that neutrophils play a protective role in the host response to infection by different intracellular parasites has been published in the past few years. We assessed this issue with regard to the infection of mice with Mycobacterium tuberculosis. We found a chronic recruitment of neutrophils to the inf...

journal_title：Infection and immunity

authors： Pedrosa J,Saunders BM,Appelberg R,Orme IM,Silva MT,Cooper AM

更新日期：2000-02-01 00:00:00

abstract：:Beta-1,2-linked mannosides (beta-Mans) are believed to contribute to Candida albicans virulence. The presence of beta-Mans has been chemically established for two molecules (phosphopeptidomannan [PPM] and phospholipomannan) that are noncovalently linked to the cell wall, where they correspond to specific epitopes. How...

journal_title：Infection and immunity

authors： Fradin C,Slomianny MC,Mille C,Masset A,Robert R,Sendid B,Ernst JF,Michalski JC,Poulain D

更新日期：2008-10-01 00:00:00

abstract：:An established cell line (Vero) defective in interferon production was used to evaluate the role of interferon in chronic rubella virus infections of cell cultures. Inoculation of Vero cells with a low multiplicity of virus resulted in the development of carrier cultures which had the characteristics of a regulated in...

journal_title：Infection and immunity

authors： Mifune K,Desmyter J,Rawls WE

更新日期：1970-08-01 00:00:00

abstract：:Pathogenic strains of Yersinia spp. inject a set of Yop effector proteins into eukaryotic cells by using a plasmid-encoded type III secretion system. In this study, we analyzed the inflammatory response of human umbilical vein endothelial cells (HUVECs) after infection with different Yersinia enterocolitica strains. W...

journal_title：Infection and immunity

authors： Denecker G,Tötemeyer S,Mota LJ,Troisfontaines P,Lambermont I,Youta C,Stainier I,Ackermann M,Cornelis GR

更新日期：2002-07-01 00:00:00

abstract：:gamma delta T cells have variously been implicated in the protection against, and the pathogenesis of, malaria, but few studies have examined the gamma delta T-cell response to malaria in African children, who suffer the large majority of malaria-associated morbidity and mortality. This is unfortunate, since available...

journal_title：Infection and immunity

authors： Hviid L,Kurtzhals JA,Adabayeri V,Loizon S,Kemp K,Goka BQ,Lim A,Mercereau-Puijalon O,Akanmori BD,Behr C

更新日期：2001-05-01 00:00:00

abstract：:Salivary proline-rich proteins (PRPs), which were purified from parotid saliva, were adsorbed onto 15-nm-diameter gold particles to visualize specific binding of the salivary molecules to Actinomyces viscosus type 1 fimbriae. Negatively stained preparations incubated with PRP-gold conjugates but not bovine serum album...

journal_title：Infection and immunity

authors： Leung KP,Nesbitt WE,Fischlschweiger W,Hay DI,Clark WB

更新日期：1990-06-01 00:00:00