Effect of chemical and heat inactivation on the antigenicity and immunogenicity of Vibrio cholerae.

abstract：:This study examined apoptotic cell death associated with Shiga-like toxin (Stx)-producing Escherichia coli. Renal cortices from three children with postenteropathic hemolytic-uremic syndrome (HUS) and from mice infected with E. coli O157:H7 and pediatric renal tubular epithelial cells stimulated with Stx and E. coli O...

journal_title：Infection and immunity

authors： Karpman D,Håkansson A,Perez MT,Isaksson C,Carlemalm E,Caprioli A,Svanborg C

更新日期：1998-02-01 00:00:00

abstract：:A protein antigen called TR-o was isolated from supernatant of a sonically treated Reiter treponeme. The isolation procedure included anion-exchange chromatography on Whatman DE-52, hydrophobic interaction chromatography on decyl agarose, and finally gel filtration on Ac-A-22 Ultrogel. The fractionations were monitore...

journal_title：Infection and immunity

authors： Petersen CS,Pedersen NS,Axelsen NH

更新日期：1982-03-01 00:00:00

abstract：:Cryptococcus neoformans laccase expression during murine infection was investigated in lung tissue by immunohistochemistry and immunogold electron microscopy. Laccase was detected in the fungal cell cytoplasm, cell wall, and capsule in vivo. The amount of laccase found in different sites varied as a function of the ti...

journal_title：Infection and immunity

authors： Garcia-Rivera J,Tucker SC,Feldmesser M,Williamson PR,Casadevall A

更新日期：2005-05-01 00:00:00

abstract：:Antimicrobial peptides play an important role in host defense against Vibrio cholerae Generally, the V. cholerae O1 classical biotype is polymyxin B (PB) sensitive and El Tor is relatively resistant. Detection of classical biotype traits like the production of classical cholera toxin and PB sensitivity in El Tor strai...

journal_title：Infection and immunity

authors： Samanta P,Mandal RS,Saha RN,Shaw S,Ghosh P,Dutta S,Ghosh A,Imamura D,Morita M,Ohnishi M,Ramamurthy T,Mukhopadhyay AK

更新日期：2020-04-20 00:00:00

abstract：:Recent studies have shown that children with blood group A have increased susceptibility to enterotoxigenic Escherichia coli (ETEC) diarrhea and that Lewis blood group "a" antigen (Le(a)) may be a candidate receptor for ETEC colonization factor (CF) antigen I (CFA/I) fimbriae. Based on these findings, we have attempte...

journal_title：Infection and immunity

authors： Ahmed T,Lundgren A,Arifuzzaman M,Qadri F,Teneberg S,Svennerholm AM

更新日期：2009-05-01 00:00:00

abstract：:The fucose-mannose ligand (FML) complex of Leishmania donovani is a promising vaccine candidate against murine and canine visceral leishmaniasis, and its main component is a 36-kDa nucleoside hydrolase (NH36). In this study, we tested the immune response and protection induced by the purified FML, the recombinant NH36...

journal_title：Infection and immunity

authors： Aguilar-Be I,da Silva Zardo R,Paraguai de Souza E,Borja-Cabrera GP,Rosado-Vallado M,Mut-Martin M,García-Miss Mdel R,Palatnik de Sousa CB,Dumonteil E

更新日期：2005-02-01 00:00:00

abstract：:In this study we used Escherichia coli strain F11(P155) of porcine origin. The heat-stable enterotoxin (ST) was produced with a batch fermentor under agitation (500 rpm) and forced aeration (5 liters/min) in Casamino Acids yeast extract medium containing 0.2% glucose. The pH varied from 7.2 to 7.8. The maximum amount ...

journal_title：Infection and immunity

authors： Lallier R,Lariviere S,St-Pierre S

更新日期：1980-05-01 00:00:00

abstract：:Sendai virus is one of the more prevalent and serious virus infections of rodents. Infection was found in 66% of the mouse, 63% of the rat, 83% of the hamster, and 44% of the guinea pig colonies examined. Twenty-four inbred and outbred strains of mice were tested for their sensitivity to lethal Sendai virus infection....

journal_title：Infection and immunity

authors： Parker JC,Whiteman MD,Richter CB

更新日期：1978-01-01 00:00:00

abstract：:The three most abundant extracellular proteins of Mycobacterium tuberculosis, the 30-, 32-, and 16-kDa major extracellular proteins, are particularly promising vaccine candidates. We have mapped T-cell epitopes of these three proteins in outbred guinea pigs by immunizing the animals with each protein and assaying sple...

journal_title：Infection and immunity

authors： Lee BY,Horwitz MA

更新日期：1999-05-01 00:00:00

abstract：:Campylobacter jejuni is a microaerobic bacterium that produces an acute, self-limiting, watery or bloody diarrhea in humans. Little is known about how C. jejuni causes disease or even what specific capabilities it requires for survival in vivo. The enzyme, superoxide dismutase (SOD), which catalyzes the breakdown of s...

journal_title：Infection and immunity

authors： Pesci EC,Cottle DL,Pickett CL

更新日期：1994-07-01 00:00:00

abstract：:P.69 pertactin (P.69 Prn), an adhesion molecule from the causative agent of pertussis, Bordetella pertussis, is present in cellular and most acellular vaccines that are currently used worldwide. Although both humoral immunity and cellular immunity directed against P.69 Prn have been implicated in protective immune mec...

journal_title：Infection and immunity

authors： Stenger RM,Poelen MC,Moret EE,Kuipers B,Bruijns SC,Hoogerhout P,Hijnen M,King AJ,Mooi FR,Boog CJ,van Els CA

更新日期：2009-02-01 00:00:00

abstract：:It was demonstrated that complement-coated sheep erythrocytes bind to Candida albicans cells grown in serum-free RPMI 1640 medium. Testing of purified complement components proved that iC3b and C3d were responsible for the reaction, whereas C3b and C3b-H reacted only slightly if at all. Binding occurred only to C. alb...

journal_title：Infection and immunity

authors： Heidenreich F,Dierich MP

更新日期：1985-11-01 00:00:00

abstract：:Rabbit endogenous pyrogens were of about the same molecular size, but showed considerable heterogeneity of their isoelectric points. We attempted to show that this heterogeneity was attributable to variable glycosylation of a single polypeptide chain. When peritoneal exudate cells were stimulated to make pyrogens in t...

journal_title：Infection and immunity

authors： Murphy PA,Cebula TA,Windle BE

更新日期：1981-10-01 00:00:00

abstract：:Controversy persists over the role that the capsular polysaccharide plays in the pathogenesis of Staphylococcus aureus infections. To address this issue, we compared the mouse virulence of S. aureus Reynolds and capsule-defective mutant strains cultivated under conditions of high or low capsule expression. Strain Reyn...

journal_title：Infection and immunity

authors： Thakker M,Park JS,Carey V,Lee JC

更新日期：1998-11-01 00:00:00

abstract：:Some species of the genus Mycoplasma code for the arginine deiminase pathway (ADI), which enables these bacteria to produce ATP from arginine by the successive reaction of three enzymes: arginine deiminase (ArcA), ornithine carbamoyltransferase (ArcB), and carbamate kinase (ArcC). It so far appears that independently ...

journal_title：Infection and immunity

authors： Rechnitzer H,Rottem S,Herrmann R

更新日期：2013-10-01 00:00:00

abstract：:Four mouse monoclonal antibodies have been developed which react with Mycobacterium tuberculosis antigen 5. Each of these monoclonal antibodies has been used to prepare immunoabsorbents, and antigen has been isolated from unheated M. tuberculosis H37Ra culture filtrate by affinity chromatography with these absorbents....

journal_title：Infection and immunity

authors： Daniel TM,Gonchoroff NJ,Katzmann JA,Olds GR

更新日期：1984-07-01 00:00:00

abstract：:This study was designed to define the lipopolysaccharide (LPS) sensitivity of aged mice in terms of lethality and cytokine production and to determine down-regulating responses of corticosterone and interleukin 10 (IL-10). The 50% lethal doses of LPS in young (6- to 7-week-old) and aged (98- to 102-week-old) mice were...

journal_title：Infection and immunity

authors： Tateda K,Matsumoto T,Miyazaki S,Yamaguchi K

更新日期：1996-03-01 00:00:00

abstract：:Staphylococcal enterotoxins A through D (SEA through SED) and toxic shock syndrome toxin-1 display superantigen properties, i.e., they stimulate a great fraction of T cells expressing certain T-cell receptor V beta sequences. Using a newly established rat model of septic Staphylococcus aureus arthritis, we have recent...

journal_title：Infection and immunity

authors： Bremell T,Tarkowski A

更新日期：1995-10-01 00:00:00

abstract：:Previous studies have reported that human vascular endothelial cells lack the membrane-bound lipopolysaccharide (LPS) receptor, CD14 (mCD14). By optimizing assay conditions, including the selection of anti-CD14 monoclonal antibody, we now demonstrate that human umbilical vein endothelial cells (HUVEC) express CD14 on ...

journal_title：Infection and immunity

authors： Jersmann HP,Hii CS,Hodge GL,Ferrante A

更新日期：2001-01-01 00:00:00

abstract：:We have investigated the role of lipoteichoic acid in mediating the adherence of different serotypes of group B streptococci to human adult and neonatal epithelial cells. Pretreatment of neonatal buccal and vaginal epithelial cells with lipoteichoic acid, but not with deacylated lipoteichoic acid, induced a marked inh...

journal_title：Infection and immunity

authors： Teti G,Tomasello F,Chiofalo MS,Orefici G,Mastroeni P

更新日期：1987-12-01 00:00:00

abstract：:Resurgence is a major concern after malaria elimination. After the initiation of the elimination program on Aneityum Island in 1991, microscopy showed that Plasmodium falciparum disappeared immediately, whereas P. vivax disappeared from 1996 onward, until P. vivax cases were reported in January 2002. By conducting mal...

journal_title：Infection and immunity

authors： Kaneko A,Chaves LF,Taleo G,Kalkoa M,Isozumi R,Wickremasinghe R,Perlmann H,Takeo S,Tsuboi T,Tachibana S,Kimura M,Björkman A,Troye-Blomberg M,Tanabe K,Drakeley C

更新日期：2014-01-01 00:00:00

abstract：:Strain TG is a plasmidless exfoliative toxin (ET) producer. Strain ER201 contains a plasmid, whose loss had no apparent effect on ET production. The plasmid of ER201 was almost identical in size to the plasmid from strain UT0007, which carries an ET determinant. ...

journal_title：Infection and immunity

authors： Rosenblum ED,Tyrone S

更新日期：1976-11-01 00:00:00

abstract：:Gamma interferon (IFN-gamma)-activated macrophages use an alternative processing mechanism to present Salmonella antigens to CD8(+) T lymphocytes. This pathway involves processing of antigen in a vacuolar compartment followed by secretion and loading of antigenic peptides to major histocompatibility complex class I (M...

journal_title：Infection and immunity

authors： Rosales-Reyes R,Alpuche-Aranda C,Ramírez-Aguilar Mde L,Castro-Eguiluz AD,Ortiz-Navarrete V

更新日期：2005-07-01 00:00:00

abstract：:Two glucosyltransferase genes from Streptococcus mutans GS-5, gtfB and gtfC, have been previously isolated and sequenced in this laboratory. In the present communication a third gtf gene, gtfD, was isolated and characterized. Isolation of the gene involved a novel procedure utilizing the integration plasmid pVA891. A ...

journal_title：Infection and immunity

authors： Hanada N,Kuramitsu HK

更新日期：1989-07-01 00:00:00

abstract：:Antiprotein monoclonal antibodies derived from mice inoculated with Rickettsia rickettsii heated at 56 degrees C for 15 min are of two types: one is type specific for epitopes denatured by moderate temperatures, and the other is specific for epitopes resistant to 100 degrees C for 5 min. The heat-resistant epitopes ar...

journal_title：Infection and immunity

authors： Anacker RL,McDonald GA,List RH,Mann RE

更新日期：1987-03-01 00:00:00

abstract：:Antigens were extracted from a virulent isolate of Pasteurella multocida (serotype 3, 12, 15:D) with potassium thiocyanate, and a vaccine was prepared. Pasteurella-free rabbits were vaccinated intranasally and intraconjuctivally twice with a 2-week interval and challenged intranasally with the homologous P. multocida ...

journal_title：Infection and immunity

authors： Ringler DH,Peter GK,Chrisp CE,Keren DF

更新日期：1985-09-01 00:00:00

abstract：:Escherichia coli strains that cause nonbloody diarrhea in infants are known to present three distinct patterns of adherence to epithelial cells, namely, localized (LA), diffuse (DA), and aggregative (AA) adherence. Strains with LA (typical Enteropathogenic Escherichia coli [EPEC]) are well recognized as a cause of sec...

journal_title：Infection and immunity

authors： Scaletsky IC,Pedroso MZ,Oliva CA,Carvalho RL,Morais MB,Fagundes-Neto U

更新日期：1999-07-01 00:00:00

abstract：:A large-scale DNA vaccination trial was performed with sheep to investigate whether an antigen targeted by CTLA-4 enhanced and accelerated the humoral immune response. Vaccination with genetically detoxified phospholipase D (DeltaPLD) has been shown to be effective, at least partially, against Corynebacterium pseudotu...

journal_title：Infection and immunity

authors： Chaplin PJ,De Rose R,Boyle JS,McWaters P,Kelly J,Tennent JM,Lew AM,Scheerlinck JP

更新日期：1999-12-01 00:00:00

abstract：:Members of the babesial rhoptry-associated protein 1 (RAP-1) family express surface-exposed B-cell epitopes and are candidate antigens for vaccine development. The relationship between rap-1 genomic polymorphism and surface-exposed B-cell epitope expression was analyzed by comparison of biological clones of Mexico str...

journal_title：Infection and immunity

authors： Suarez CE,McElwain TF,Echaide I,Torioni de Echaide S,Palmer GH

更新日期：1994-08-01 00:00:00

abstract：:Vibrio cholerae neuraminidase (NANase) is hypothesized to act synergistically with cholera toxin (CT) and increase the severity of a secretory response by increasing the binding and penetration of CT to enterocytes. To test this hypothesis, the NANase gene (nanH) from V. cholerae Ogawa 395 was first cloned and sequenc...

journal_title：Infection and immunity

authors： Galen JE,Ketley JM,Fasano A,Richardson SH,Wasserman SS,Kaper JB

更新日期：1992-02-01 00:00:00