Laccase expression in murine pulmonary Cryptococcus neoformans infection.

abstract：:A hybridoma produced by the polyethylene glycol fusion of the NS-1 variant of the P3x63Ag8 BALB/c plasmacytoma to splenocytes harvested from a BALB/c mouse immunized with whole gonococci was found to be producing antibody to a common region on gonococcal lipopolysaccharide (LPS). Enzyme-linked immunosorbent assay inhi...

journal_title：Infection and immunity

authors： Apicella MA,Bennett KM,Hermerath CA,Roberts DE

更新日期：1981-12-01 00:00:00

abstract：:The role of type 1 pili in promoting bladder colonization was examined by constructing two mutant strains of a clinical Escherichia coli isolate. One mutant was isogenic to the parental strain save for a lesion in a gene required for pilus receptor binding; the other mutant was isogenic save for a lesion in the gene e...

journal_title：Infection and immunity

authors： Keith BR,Maurer L,Spears PA,Orndorff PE

更新日期：1986-09-01 00:00:00

abstract：:Monoclonal antibodies against 12 of the 17 IATS serotype strains of Pseudomonas aeruginosa were produced. Eighty-seven hybridoma clones were isolated, and the antibodies secreted were found to be reactive with both Formalin-fixed whole cells and purified lipopolysaccharide of homologous strains in enzyme-linked immuno...

journal_title：Infection and immunity

authors： Lam JS,MacDonald LA,Lam MY,Duchesne LG,Southam GG

更新日期：1987-05-01 00:00:00

abstract：:The Syrian golden hamster (Mesocricetus auratus) is uniquely susceptible to a variety of intracellular pathogens and is an excellent model for a number of human infectious diseases. The molecular basis for this high level of susceptibility is unknown, and immunological studies related to this model have been limited b...

journal_title：Infection and immunity

authors： Melby PC,Tryon VV,Chandrasekar B,Freeman GL

更新日期：1998-05-01 00:00:00

abstract：:Guinea pigs sensitized by repeated skin testing with potent, merthiolated coccidioidin, equal to Smith standard, exhibited erythema, edema, and an induration-like reaction to intradermal injection of the preparation. No statistically significant migration inhibition of peritoneal exudate macrophages from these animals...

journal_title：Infection and immunity

authors： Sinski JT,Reed GL,Kelley LM,LeFebvre R

更新日期：1973-02-01 00:00:00

abstract：:Hydroxystilbamidine (HSB) is a potent suppressor of the plaque-forming cell response of mice injected with heterologous erythrocytes. HSB, given in varying doses and injection schedules, suppressed both the primary and secondary immune responses to bovine serum albumin. Apparently the effect is not simply a toxic effe...

journal_title：Infection and immunity

authors： Folds JD,Orlando G,Spitznagel JK

更新日期：1975-03-01 00:00:00

abstract：:Tuberculosis remains a leading killer worldwide, and new approaches for its treatment and prevention are urgently needed. This effort will benefit greatly from a better understanding of gene regulation in Mycobacterium tuberculosis, particularly with respect to this pathogen's response to its host environment. We exam...

journal_title：Infection and immunity

authors： Purkayastha A,McCue LA,McDonough KA

更新日期：2002-03-01 00:00:00

abstract：:The unique permissiveness of A/J mouse macrophages for replication of Legionella pneumophila is caused by a deficiency in the Nod-like receptor (NLR) protein and intracellular sensor for L. pneumophila flagellin (Naip5). The signaling pathways and proteins activated by Naip5 sensing in macrophages were investigated. T...

journal_title：Infection and immunity

authors： Fortier A,Doiron K,Saleh M,Grinstein S,Gros P

更新日期：2009-11-01 00:00:00

abstract：:A high-molecular-weight, immunogenic form of the lipopolysaccharide O side chain of Pseudomonas aeruginosa Fisher immunotype 4 (type 4, International Antigenic Typing System 1, Lanyi O:6) was isolated and characterized. Analysis by nuclear magnetic resonance spectroscopy confirmed the structural similarity of this hig...

journal_title：Infection and immunity

authors： Pier GB,Pollack M

更新日期：1989-02-01 00:00:00

abstract：:A veronal buffer extract of Salmonella typhi was used as the reference antigen and its corresponding rabbit antiserum as the reference antibody in crossed immunoelectrophoresis to analyze antibodies in sera obtained from typhoid patients and carriers. Four precipitating antibodies were regularly detected. Three were a...

journal_title：Infection and immunity

authors： Chau PY,Wan KC,Tsang RS

更新日期：1984-03-01 00:00:00

abstract：:We used an in vitro opsonophagocytic killing assay to measure the functional activity of antibody directed at the mucoid exopolysaccharide (MEP) antigen expressed by Pseudomonas aeruginosa strains isolated from cystic fibrosis patients. Rabbit antibodies raised to purified MEP were able to mediate phagocytic killing i...

journal_title：Infection and immunity

authors： Ames P,DesJardins D,Pier GB

更新日期：1985-08-01 00:00:00

abstract：:Bacillary angiomatosis (BA), one of the many clinical manifestations resulting from infection with the facultative intracellular bacterium Bartonella henselae, is characterized by angiogenic lesions. Macrophages have been identified as important effector cells contributing to the angiogenic process during B. henselae ...

journal_title：Infection and immunity

authors： McCord AM,Burgess AW,Whaley MJ,Anderson BE

更新日期：2005-09-01 00:00:00

abstract：:Oral or intravenous inoculation of previously unexposed juvenile and adult ferrets with Campylobacter jejuni uniformly resulted in intestinal colonization lasting 2 to 12 days. Disease varied from mild to moderate diarrhea, which resolved in 2 to 3 days. Orally infected animals developed agglutinin titers of 8 to 256 ...

journal_title：Infection and immunity

authors： Bell JA,Manning DD

更新日期：1990-06-01 00:00:00

abstract：:The yields of exotoxin A in Pseudomonas aeruginosa cultures were influenced by the concentration of iron in the culture media. When the iron concentration of the culture media was increased from 0.05 to 1.5 microgram/ml, there was at least a 90% decrease in exotoxin A (measured both by enzymatic activity and by mouse ...

journal_title：Infection and immunity

authors： Bjorn MJ,Iglewski BH,Ives SK,Sadoff JC,Vasil ML

更新日期：1978-03-01 00:00:00

abstract：:A substance with potent decomplementation activity was isolated from staphylococcal culture supernatants by polyethylene glycol precipitation, DEAE-ion-exchange and Sephacryl chromatography, and preparative sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The purified substance exhibited all the characterist...

journal_title：Infection and immunity

authors： Bhakdi S,Muhly M

更新日期：1985-01-01 00:00:00

abstract：:Urinary tract infections (UTIs) are among the most common infectious diseases of humans, with Escherichia coli responsible for >80% of all cases. One extreme of UTI is asymptomatic bacteriuria (ABU), which occurs as an asymptomatic carrier state that resembles commensalism. To understand the evolution and molecular me...

journal_title：Infection and immunity

authors： Beatson SA,Ben Zakour NL,Totsika M,Forde BM,Watts RE,Mabbett AN,Szubert JM,Sarkar S,Phan MD,Peters KM,Petty NK,Alikhan NF,Sullivan MJ,Gawthorne JA,Stanton-Cook M,Nhu NT,Chong TM,Yin WF,Chan KG,Hancock V,Ussery DW

更新日期：2015-05-01 00:00:00

abstract：:During the process of phagocytosis, human leukocytes emit a burst of luminescence which can be measured in a liquid scintillation spectrometer. The enzyme superoxide dismutase, which removes superoxide anions (O(2.)), inhibited this chemiluminescence by 70% at a concentration of 100 mug/ml. The enzyme did not inhibit ...

journal_title：Infection and immunity

authors： Webb LS,Keele BB Jr,Johnston RB Jr

更新日期：1974-06-01 00:00:00

abstract：:Entamoeba histolytica virulence is related to a number of amebic components (lectins, cysteine proteinases, and amebapore) and host factors, such as intestinal bacterial flora. Trophozoites are selective in their interactions with bacteria, and the parasite recognition of glycoconjugates plays an important role in ame...

journal_title：Infection and immunity

authors： Padilla-Vaca F,Ankri S,Bracha R,Koole LA,Mirelman D

更新日期：1999-05-01 00:00:00

abstract：:A rapid and reproducible method of bacteriocin typing is described based on leakage of ultraviolet light-absorbing material (UVAM), detectable in supernatants of bacteriocin-sensitive cultures, by means of a spectrophotometer. The prerequisites for reproducible results, with nonsignificant fluctuations in standard err...

journal_title：Infection and immunity

authors： Farkas-Himsley H,Pagel A

更新日期：1977-04-01 00:00:00

abstract：:(DBA/N[female] X CBA/2[male])F1 males have been reported to be deficient in producing antibodies against a number of antigens, including carbohydrates (I. Scher, Adv. Immunol. 35:1-71, 1982). We show that F1 male mice, in contrast to females, made less lipopolysaccharide (LPS)-specific antibodies after immunization wi...

journal_title：Infection and immunity

authors： Zweerink HJ,Gammon MC,Hutchison CF,Jackson JJ,Pier GB,Puckett JM,Sewell TJ,Sigal NH

更新日期：1988-05-01 00:00:00

abstract：:In the present study, we have investigated the evolution and impact on virulence of a 350-kb genomic duplication present in the most recently evolved members of the Mycobacterium tuberculosis East Asian lineage. In a mouse model of infection, comparing HN878 subclones HN878-27 (no duplication) and HN878-45 (with the 3...

journal_title：Infection and immunity

authors： Domenech P,Rog A,Moolji JU,Radomski N,Fallow A,Leon-Solis L,Bowes J,Behr MA,Reed MB

更新日期：2014-07-01 00:00:00

abstract：:Conventional dendritic cells (cDCs) are critical for protection against pulmonary infection with the opportunistic fungal pathogen Cryptococcus neoformans; however, the role of plasmacytoid dendritic cells (pDCs) is unknown. We show for the first time that murine pDCs have direct activity against C. neoformans via rea...

journal_title：Infection and immunity

authors： Hole CR,Leopold Wager CM,Mendiola AS,Wozniak KL,Campuzano A,Lin X,Wormley FL Jr

更新日期：2016-08-19 00:00:00

abstract：:Malaria infection caused by Plasmodium parasites continues to cause enormous morbidity and mortality in areas where it is endemic, and there is no licensed vaccine capable of inducing sterile protection. Hyperimmunization with attenuated whole sporozoites can induce sterile protective immune responses targeting preery...

journal_title：Infection and immunity

authors： Billman ZP,Seilie AM,Murphy SC

更新日期：2016-07-21 00:00:00

abstract：:Active immunization of mice with high doses of heat-killed and autoclaved vaccine of unencapsulated strains of Staphylococcus aureus, which was grown in brain heart infusion media, protected against challenge with the Smith diffuse strain of Staphylococcus aureus. These organisms were capable of absorbing the protecti...

journal_title：Infection and immunity

authors： Yoshida K,Ichiman Y,Otomo T

更新日期：1975-11-01 00:00:00

abstract：:FMS-like tyrosine kinase-3 ligand (Flt3L) is a dendritic cell (DC) growth and differentiation factor with potential in antitumor therapies and antibacterial immunization strategies. However, the effect of systemic Flt3L treatment on lung-protective immunity against bacterial infection is incompletely defined. Here, we...

journal_title：Infection and immunity

authors： Brumshagen C,Maus R,Bischof A,Ueberberg B,Bohling J,Osterholzer JJ,Ogunniyi AD,Paton JC,Welte T,Maus UA

更新日期：2012-12-01 00:00:00

abstract：:Most children and adults living in areas where the endemicity of Plasmodium falciparum malaria is high have significantly elevated levels of both total immunoglobulin E (IgE) and IgE antimalarial antibodies in blood. This elevation is highest in patients with cerebral malaria, suggesting a pathogenic role for this imm...

journal_title：Infection and immunity

authors： Perlmann P,Perlmann H,Flyg BW,Hagstedt M,Elghazali G,Worku S,Fernandez V,Rutta AS,Troye-Blomberg M

更新日期：1997-01-01 00:00:00

abstract：:Pseudomonas aeruginosa invades various epithelial cell types in vitro and in vivo. The P. aeruginosa genome possesses a gene (flhA) which encodes a protein that is believed to be part of the export apparatus for flagellum assembly and which is homologous to invA of Salmonella spp. Because invA is required for invasion...

journal_title：Infection and immunity

authors： Fleiszig SM,Arora SK,Van R,Ramphal R

更新日期：2001-08-01 00:00:00

abstract：:Adherence to fibrinogen and fibronectin plays a crucial role in Staphylococcus aureus experimental endocarditis. Previous genetic studies have shown that infection and carriage isolates do not systematically differ in their virulence-related genes, including genes conferring adherence, such as clfA and fnbA. We set ou...

journal_title：Infection and immunity

authors： Ythier M,Entenza JM,Bille J,Vandenesch F,Bes M,Moreillon P,Sakwinska O

更新日期：2010-04-01 00:00:00

abstract：:Staphylococcus aureus is a pathogen often found in pneumonia and sepsis. In the context of the resistance of this organism to conventional antibiotics, an understanding of the regulation of natural endogenous antimicrobial molecules is of paramount importance. Previous studies have shown that both human and mouse airw...

journal_title：Infection and immunity

authors： McMichael JW,Maxwell AI,Hayashi K,Taylor K,Wallace WA,Govan JR,Dorin JR,Sallenave JM

更新日期：2005-06-01 00:00:00

abstract：:Recent studies have established the importance of neutrophils in innate resistance to Listeria monocytogenes infection in mice. The purpose of this study was to determine the importance of neutrophils in acquired resistance to L. monocytogenes infection. Previously immunized mice that were depleted of neutrophils by a...

journal_title：Infection and immunity

authors： Czuprynski CJ,Brown JF,Wagner RD,Steinberg H

更新日期：1994-11-01 00:00:00